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2019

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases (vol 9, 1864, 2018)

Blue Mountains Eye Study-GWAS Grp, NEIGHBORHOOD Consortium & Wellcome Trust Case Control, 8 Jan 2019, In : Nature Communications. 10, 3 p., 155.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Current state and future prospects of artificial intelligence in ophthalmology: a review

Hogarty, D. T., Mackey, D. A. & Hewitt, A. W., Jan 2019, In : Clinical and Experimental Ophthalmology. 47, 1, p. 128-139 12 p.

Research output: Contribution to journalReview article

Open Access
60 Downloads (Pure)

Differential stability of variant OPN1LW gene transcripts in myopic patients

Mountford, J. K., Davies, W. I. L., Griffiths, L. R., Yazar, S., Mackey, D. A. & Hunt, D. M., 1 Jan 2019, In : Molecular Vision. 25, p. 183-193 11 p.

Research output: Contribution to journalArticle

Open Access
File
Opsins
Genes
Nucleotides
Melanesia
RNA

Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

Spracklen, C. N., Karaderi, T., Yaghootkar, H., Schurmann, C., Fine, R. S., Kutalik, Z., Preuss, M. H., Lu, Y., Wittemans, L. B. L., Adair, L. S., Allison, M., Amin, N., Auer, P. L., Bartz, T. M., Blueher, M., Boehnke, M., Borja, J. B., Bork-Jensen, J., Broer, L., Chasman, D. I. & 84 othersChen, Y-D. I., Chirstofidou, P., Demirkan, A., van Duijn, C. M., Feitosa, M. F., Garcia, M. E., Graff, M., Grallert, H., Grarup, N., Guo, X., Haesser, J., Hansen, T., Harris, T. B., Highland, H. M., Hong, J., Ikram, M. A., Ingelsson, E., Jackson, R., Jousilahti, P., Kahonen, M., Kizer, J. R., Kovacs, P., Kriebel, J., Laakso, M., Lange, L. A., Lehtimaki, T., Li, J., Ruifang Li-Gao, Lind, L., Luan, J., Lyytikainen, L-P., MacGregor, S., Mackey, D. A., Mahajan, A., Mangino, M., Mannisto, S., McCarthy, M. I., McKnight, B., Medina-Gomez, C., Meigs, J. B., Molnos, S., Mook-Kanamori, D., Morris, A. P., de Mutsert, R., Nalls, M. A., Nedeljkovic, I., North, K. E., Pennell, C. E., Pradhan, A. D., Province, M. A., Raitakari, O. T., Raulerson, C. K., Reiner, A. P., Ridker, P. M., Ripatti, S., Roberston, N., Rotter, J. I., Salomaa, V., Sandoval-Zarate, A. A., Sitlani, C. M., Spector, T. D., Strauch, K., Stumvoll, M., Taylor, K. D., Thuesen, B., Toenjes, A., Uitterlinden, A. G., Venturini, C., Walker, M., Wang, C. A., Wang, S., Wareham, N. J., Willems, S. M., van Dijk, K. W., Wilson, J. G., Wu, Y., Yao, J., Young, K. L., Langenberg, C., Frayling, T. M., Kilpelainen, T. O., Lindgren, C. M., Loos, R. J. F. & Mohlke, K. L., 3 Jul 2019, In : American Journal of Human Genetics. 105, 1, p. 15-28 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Eye Injuries across history and the evolution of eye protection

Hoskin, A. K., Mackey, D. A., Keay, L., Agrawal, R. & Watson, S., 25 Mar 2019, In : Acta Ophthalmologica.

Research output: Contribution to journalArticle

Eye Injuries
History
Wounds and Injuries
Workplace
Publications
3 Citations (Scopus)

IMI - Myopia Genetics Report

CREAM Consortium, Feb 2019, In : Investigative ophthalmology & visual science. 60, 3, p. M89-M105 17 p.

Research output: Contribution to journalArticle

Open Access

Mobile touch screen device use and associations with musculoskeletal symptoms and visual health in a nationally representative sample of Singaporean adolescents

Toh, S. H., Coenen, P., Howie, E. K., Mukherjee, S., Mackey, D. A. & Straker, L. M., 3 Jun 2019, In : Ergonomics. 62, 6, p. 778-793 16 p.

Research output: Contribution to journalArticle

Touch screens
Smartphones
Health
adolescent
Equipment and Supplies
2 Citations (Scopus)

Myocilin Gene Gln368Ter Variant Penetrance and Association With Glaucoma in Population-Based and Registry-Based Studies

Han, X., Souzeau, E., Ong, J-S., An, J., Siggs, O. M., Bunion, K. P., Best, S., Goldberg, I., Healey, P. R., Graham, S. L., Ruddle, J. B., Mills, R. A., Landers, J., Galanopoulos, A., White, A. J. R., Casson, R., Mackey, D. A., Hewitt, A. W., Gharahkhani, P., Craig, J. E. & 1 othersMacGregor, S., Jan 2019, In : JAMA Ophthalmology. 137, 1, p. 28-35 8 p.

Research output: Contribution to journalArticle

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (vol 9, 4774, 2018)

Melanoma GWAS Consortium, 14 Jan 2019, In : Nature Communications. 10, 3 p., 299.

Research output: Contribution to journalComment/debate

Open Access
2 Citations (Scopus)

Prevalence of FOXC1 Variants in Individuals with a Suspected Diagnosis of Primary Congenital Glaucoma

Siggs, O. M., Souzeau, E., Pasutto, F., Dubowsky, A., Smith, J. E. H., Taranath, D., Pater, J., Rait, J. L., Narita, A., Mauri, L., Del Longo, A., Reis, A., Chappell, A., Kearns, L. S., Staffieri, S. E., Elder, J. E., Ruddle, J. B., Hewitt, A. W., Burdon, K. P., Mackey, D. A. & 1 othersCraig, J. E., 1 Apr 2019, In : JAMA Ophthalmology. 137, 4, p. 348-355 8 p.

Research output: Contribution to journalArticle

Glaucoma
Exome
Genetic Heterogeneity
Multiplex Polymerase Chain Reaction
Ophthalmology

Repurposing blue laser autofluorescence to measure ocular sun exposure

Lingham, G., Burton, A., Brown, H. A., Huynh, E., Yazar, S., Coroneo, M. T. & Mackey, D. A., May 2019, In : Clinical and Experimental Ophthalmology. p. 445-452 8 p.

Research output: Contribution to journalArticle

Solar System
Lasers
Ophthalmoscopes
Pterygium
Western Australia

Seeing the impact of the Glaucoma Inheritance Study in Tasmania after 25 years

Mackey, D. A., Craig, J. E. & Hewitt, A. W., Jul 2019, In : Clinical and Experimental Ophthalmology. 47, 5, p. 677-679 3 p.

Research output: Contribution to journalLetter

The challenge of an adequate outcome in trials for genetic eye disease such as Leber hereditary optic neuropathy

Mackey, D. A. & Kearns, L. S., Aug 2019, In : Clinical and Experimental Ophthalmology. 47, 6, p. 704-705 2 p.

Research output: Contribution to journalEditorial

The relationship between optic disc parameters and female reproductive factors in young women

Lee, S. S. Y., Yazar, S., Pasquale, L. R., Sanfilippo, P. G., Hewitt, A. W., Hickey, M., Skinner, R. & Mackey, D. A., May 2019, In : Asia-Pacific Journal of Ophthalmology. 8, 3, p. 224-228 5 p.

Research output: Contribution to journalArticle

Optic Disk
Contraceptive Agents
Glaucoma
Menarche
Parity

Traumatic hyphaema in children: a retrospective and prospective study of outcomes at an Australian paediatric centre

Richards, M. D., Barnes, K., Yardley, A. M. E., Hanman, K., Lam, G. C. & Mackey, D. A., 1 Jan 2019, In : BMJ Open Ophthalmology. 4, 1, e000215.

Research output: Contribution to journalArticle

Open Access
Hyphema
Retrospective Studies
Prospective Studies
Pediatrics
Wounds and Injuries
2 Citations (Scopus)
105 Downloads (Pure)

Vitamin D and its pathway genes in myopia: Systematic review and meta-analysis

Tang, S. M., Lau, T., Rong, S. S., Yazar, S., Chen, L. J., Mackey, D. A., Lucas, R. M., Pang, C. P. & Yam, J. C., 1 Jan 2019, In : British Journal of Ophthalmology. 103, 1, p. 8-17

Research output: Contribution to journalReview article

Open Access
File
Myopia
Vitamin D
Meta-Analysis
Genes
Odds Ratio
2018

119 loci influencing intraocular pressure provide new insight into primary open angle glaucoma susceptibility and age of onset.

Craig, J. E., Hewitt, A. W., Mackey, D., Graham, S. L., Healey, P. R., White, A. J. R., Landers, J., Casson, R., Souzeau, E., Burdon, K. P., Gharahkhani, P. & MacGregor, S., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p., 1177.

Research output: Contribution to journalAbstract/Meeting Abstract

2 Citations (Scopus)

Analysis combining correlated glaucoma traits identifies five new risk loci for open-angle glaucoma

Gharahkhani, P., Burdon, K. P., Cooke Bailey, J. N., Hewitt, A. W., Law, M. H., Pasquale, L. R., Kang, J. H., Haines, J. L., Souzeau, E., Zhou, T., Siggs, O. M., Landers, J., Awadalla, M., Sharma, S., Mills, R. A., Ridge, B., Lynn, D., Casson, R., Graham, S. L., Goldberg, I. & 45 othersWhite, A., Healey, P. R., Grigg, J., Lawlor, M., Mitchell, P., Ruddle, J., Coote, M., Walland, M., Best, S., Vincent, A., Gale, J., Radfordsmith, G., Whiteman, D. C., Montgomery, G. W., Martin, N. G., MacKey, D. A., Wiggs, J. L., MacGregor, S., Craig, J. E., Allingham, R. R., Brilliant, M., Budenz, D. L., Fingert, J. H., Gaasterland, D., Gaasterland, T., Hark, L., Hauser, M., Igo, R. P., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Moroi, S., Pericak-Vance, M., Realini, A., Rhee, D., Richards, J. E., Ritch, R., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Wollstein, G. & Zack, D. J., 1 Dec 2018, In : Scientific Reports. 8, 1, 3124.

Research output: Contribution to journalArticle

Open Access
Open Angle Glaucoma
Glaucoma
Genome-Wide Association Study
Eye Diseases
Chromosome Mapping

An update of the prevalence of myopia in an older Australian population

Mackey, D., Lingham, G., Lee, S., Hunter, M., Wood, D., Hewitt, A. W., Mitchell, P., Taylor, H. R. & Yazar, S., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p., 3954.

Research output: Contribution to journalAbstract/Meeting Abstract

A POLYGENIC RISK SCORE THAT PREDICTS FAMILIAL GENETIC RISK IN GLAUCOMA

Hassall, M. M., Qassim, A., Han, X., Souzeau, E., Goldberg, I., Healey, P. R., Graham, S. L., Ruddle, J., Casson, R. J., Mackey, D. A., Hewitt, A., MacGregor, S. & Craig, J. E., Nov 2018, In : Clinical and Experimental Ophthalmology. 46, p. 64-65 2 p., S2504.

Research output: Contribution to journalAbstract/Meeting Abstract

1 Citation (Scopus)
Blindness
Schizophrenia
Population
Cortical Blindness
Western Australia
2 Citations (Scopus)

Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

Iglesias, A. I., Mishra, A., Vitart, V., Bykhovskaya, Y., Höhn, R., Springelkamp, H., Cuellar-Partida, G., Gharahkhani, P., Bailey, J. N. C., Willoughby, C. E., Li, X., Yazar, S., Nag, A., Khawaja, A. P., Polašek, O., Siscovick, D., Mitchell, P., Tham, Y. C., Haines, J. L., Kearns, L. S. & 124 othersHayward, C., Shi, Y., Van Leeuwen, E. M., Taylor, K. D., Wang, J. J., Rochtchina, E., Attia, J., Scott, R., Holliday, E. G., Baird, P. N., Xie, J., Inouye, M., Viswanathan, A., Sim, X., Bonnemaijer, P., Rotter, J. I., Martin, N. G., Zeller, T., Mills, R. A., Staffieri, S. E., Jonas, J. B., Schmidtmann, I., Boutin, T., Kang, J. H., Lucas, S. E. M., Wong, T. Y., Beutel, M. E., Wilson, J. F., Allingham, R. R., Brilliant, M. H., Budenz, D. L., Christen, W. G., Fingert, J., Friedman, D. S., Gaasterland, D., Gaasterland, T., Hauser, M. A., Kraft, P., Lee, R. K., Lichter, P. R., Liu, Y., Loomis, S. J., Moroi, S. E., Pericak-Vance, M. A., Realini, A., Richards, J. E., Schuman, J. S., Scott, W. K., Singh, K., Sit, A. J., Vollrath, D., Weinreb, R. N., Wollstein, G., Zack, D. J., Zhang, K., Donnelly, P., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A., Jankowski, J., Markus, H. S., Mathew, C. G., Palmer, C. N. A., Plomin, R., Rautanen, A., Sawcer, S. J., Trembath, R. C., Wood, N. W., Spencer, C. C. A., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, R., Strange, A., Su, Z., Vukcevic, D., Langford, C., Hunt, S. E., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, S. J., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, O. T., Liddle, J., Potter, S. C., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Uitterlinden, A. G., Vithana, E. N., Foster, P. J., Hysi, P. G., Hewitt, A. W., Khor, C. C., Pasquale, L. R., Montgomery, G. W., Klaver, C. C. W., Aung, T., Pfeiffer, N., MacKey, D. A., Hammond, C. J., Cheng, C. Y., Craig, J. E., Rabinowitz, Y. S., Wiggs, J. L., Burdon, K. P., Van Duijn, C. M. & MacGregor, S., 1 Dec 2018, In : Nature Communications. 9, 1, 1864.

Research output: Contribution to journalArticle

Open Access
eye diseases
Eye Diseases
genome
Genome-Wide Association Study
Keratoconus
Open Access

Does including colour-blind men enhance search and rescue teams?

Crewe, J. M., Brown, H., Fyfe, D. & Mackey, D. A., 1 Sep 2018, In : Clinical and Experimental Ophthalmology. 46, 7, p. 817-818 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Expression QTL analysis of glaucoma endophenotypes in the Norfolk Island isolate provides evidence that immune-related genes are associated with optic disc size

Fang Kho, P., Lea, R. A., Benton, M. C., Eccles, D., Haupt, L. M., Hewitt, A. W., Sherwin, J. C., Mackey, D. A. & Griffiths, L. R., 1 Jan 2018, In : Journal of Human Genetics. 63, 1, p. 83-87 5 p.

Research output: Contribution to journalArticle

Melanesia
Endophenotypes
Optic Disk
Glaucoma
Genes
27 Citations (Scopus)

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

CREAM, 23andMe Research Team & UK Biobank Eye and Vision Consortium, 1 Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

Research output: Contribution to journalArticle

Open Access
Refractive Errors
Genome-Wide Association Study
Meta-Analysis
Light
Retina
16 Citations (Scopus)

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

Hysi, P. G., Valdes, A. M., Liu, F., Furlotte, N. A., Evans, D. M., Bataille, V., Visconti, A., Hemani, G., McMahon, G., Ring, S. M., Smith, G. D., Duffy, D. L., Zhu, G., Gordon, S. D., Medland, S. E., Lin, B. D., Willemsen, G., Jan Hottenga, J., Vuckovic, D., Girotto, G. & 24 othersGandin, I., Sala, C., Concas, M. P., Brumat, M., Gasparini, P., Toniolo, D., Cocca, M., Robino, A., Yazar, S., Hewitt, A. W., Chen, Y., Zeng, C., Uitterlinden, A. G., Ikram, M. A., Hamer, M. A., Van Duijn, C. M., Nijsten, T., MacKey, D. A., Falchi, M., Boomsma, D. I., Martin, N. G., Hinds, D. A., Kayser, M. & Spector, T. D., 1 May 2018, In : Nature Genetics. 50, 5, p. 652-656 5 p.

Research output: Contribution to journalArticle

Open Access
Hair Color
Genome-Wide Association Study
Hair
Meta-Analysis
Melanins
2 Citations (Scopus)

Genome-wide association study identifies a susceptibility locus for comitant esotropia and suggests a parent-of-origin effect

Strabismus Genetics Research Consortium, 1 Aug 2018, In : Investigative Ophthalmology and Visual Science. 59, 10, p. 4054-4064 11 p.

Research output: Contribution to journalArticle

Open Access
Esotropia
Genome-Wide Association Study
Odds Ratio
Meta-Analysis
Strabismus
11 Citations (Scopus)

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

Warrington, N. M., Shevroja, E., Hemani, G., Hysi, P. G., Jiang, Y., Auton, A., Boer, C. G., Mangino, M., Wang, C. A., Kemp, J. P., McMahon, G., Medina-Gomez, C., Hickey, M., Trajanoska, K., Wolke, D., Ikram, M. A., Montgomery, G. W., Felix, J. F., Wright, M. J., Mackey, D. A. & 11 othersJaddoe, V. W., Martin, N. G., Tung, J. Y., Smith, G. D., Pennell, C. E., Spector, T. D., van Meurs, J., Rivadeneira, F., Medland, S. E., Evans, D. M. & The 23and Me Research Team, . M. R. T., 1 Jun 2018, In : Human Molecular Genetics. 27, 11, p. 2025-2038 14 p.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Fingers
Testosterone
Biomarkers
Sample Size
8 Citations (Scopus)

Genome-wide association study identifies seven novel susceptibility loci for primary open-angle glaucoma

Japan Glaucoma Society Omics Group (JGS-OG) & NEIGHBORHOOD Consortium, 15 Apr 2018, In : Human Molecular Genetics. 27, 8, p. 1486-1496 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Primary Open Angle Glaucoma
Blindness
Epidermal Growth Factor Receptor
Glaucoma

GENOME-WIDE ASSOCIATION STUDY OF INTRAOCULAR PRESSURE IN 133,492 PEOPLE UNCOVERS NEW PATHWAYS TO GLAUCOMA AND IMPROVES DISEASE PREDICTION

Hewitt, A., MacGregor, S., Ong, J. S., An, J., Han, X., Zhou, T., Law, M., Souzeau, E., Burdon, K., Gharahkhani, P., Mackey, D. & Craig, J., Nov 2018, In : Clinical and Experimental Ophthalmology. 46, p. 37-37 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

7 Citations (Scopus)

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

MacGregor, S., Ong, J-S., An, J., Han, X., Zhou, T., Siggs, O. M., Law, M. H., Souzeau, E., Sharma, S., Lynn, D. J., Beesley, J., Sheldrick, B., Mills, R. A., Landers, J., Ruddle, J. B., Graham, S. L., Healey, P. R., White, A. J. R., Casson, R. J., Best, S. & 12 othersGrigg, J. R., Goldberg, I., Powell, J. E., Whiteman, D. C., Radford-Smith, G. L., Martin, N. G., Montgomery, G. W., Burdon, K. P., Mackey, D. A., Gharahkhani, P., Craig, J. E. & Hewitt, A. W., Aug 2018, In : Nature Genetics. 50, 8, p. 1067-+ 9 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

Int Glaucoma Genetics Consortium, NEIGHBORHOOD Consortium & Mackey, D. A., Jan 2018, In : PLoS Genetics. 14, 1, 24 p., 1007145.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
156 Downloads (Pure)
Open Access
File
Retinal Vessels
Angiography
Optical tomography
Optical Coherence Tomography
Image quality
1 Citation (Scopus)

Investigating the long-term impact of a childhood sun-exposure intervention, with a focus on eye health: protocol for the Kidskin-Young Adult Myopia Study

Lingham, G., Milne, E., Cross, D., English, D. R., Johnston, R. S., Lucas, R. M., Yazar, S. & Mackey, D. A., 31 Jan 2018, In : BMJ Open. 8, 1, p. e020868

Research output: Contribution to journalArticle

Open Access
Myopia
Solar System
Young Adult
Health
Social Media
1 Citation (Scopus)

Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis

De Smit, E., Lukowski, S. W., Anderson, L., Senabouth, A., Dauyey, K., Song, S., Wyse, B., Wheeler, L., Chen, C. Y., Cao, K., Wong Ten Yuen, A., Shuey, N., Clarke, L., Lopez Sanchez, I., Hung, S. S. C., Pébay, A., Mackey, D. A., Brown, M. A., Hewitt, A. W. & Powell, J. E., 23 Jul 2018, In : BMC Medical Genomics. 11, 1, 61.

Research output: Contribution to journalArticle

Open Access
Giant Cell Arteritis
Biomarkers
Phenotype
Transcriptome
Genes

LOW VITAMIN D LEVELS ARE NOT ASSOCIATED WITH REFRACTIVE ERROR IN MIDDLE-AGED AND OLDER WESTERN AUSTRALIAN ADULTS

Lingham, G., Yazar, S., Lucas, R. M., Walsh, J. P., Zhu, K., Hunter, M., Lim, E. M., Cooke, B. R. & Mackey, D. A., Nov 2018, In : Clinical and Experimental Ophthalmology. 46, p. 31-32 2 p., S1003.

Research output: Contribution to journalAbstract/Meeting Abstract

Mitochondrial DNA variation and disease susceptibility in primary open-angle glaucoma

Singh, L. N., Crowston, J. G., Lopez Sanchez, M. I. G., Van Bergen, N. J., Kearns, L. S., Hewitt, A. W., Yazar, S., Mackey, D. A., Wallace, D. C. & Trounce, I. A., 1 Sep 2018, In : Investigative Ophthalmology and Visual Science. 59, 11, p. 4598-4602 5 p.

Research output: Contribution to journalArticle

Open Access
Mitochondrial Diseases
Disease Susceptibility
Mitochondrial DNA
Endophenotypes
Mitochondrial Genes
6 Citations (Scopus)

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways

Melanoma GWAS Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 4774.

Research output: Contribution to journalArticle

Open Access
Nevi and Melanomas
loci
Nevus
Melanoma
genes
3 Citations (Scopus)
Pterygium
Melanoma
Skin
Western Australia
Registries

Single-cell profiling identifies key pathways expressed by iPSCs cultured in different commercial media

Daniszewski, M., Quan Nguyen, Chy, H. S., Singh, V., Crombie, D. E., Kulkarni, T., Liang, H. H., Sivakumaran, P., Lidgerwood, G. E., Hernandez, D., Conquest, A., Rooney, L. A., Chevalier, S., Andersen, S. B., Senabouth, A., Vickers, J. C., Mackey, D. A., Craig, J. E., Laslett, A. L., Hewitt, A. W. & 2 othersPowell, J. E. & Pebay, A., 28 Sep 2018, In : Iscience. 7, p. 30-39

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Testosterone pathway genetic polymorphisms in relation to primary open-angle glaucoma: An analysis in two large datasets

Australian and New Zealand Registry of Advanced Glaucoma (ANZRAG) Consortium, 1 Feb 2018, In : Investigative Ophthalmology and Visual Science. 59, 2, p. 629-636 8 p.

Research output: Contribution to journalArticle

Open Access
Genetic Polymorphisms
Testosterone
Genes
Single Nucleotide Polymorphism
Low Tension Glaucoma

The relationship between female reproductive factors and optic disc parameters in young female adults

Lee, S., Yazar, S., Pasquale, L. R., Sanfilippo, P., Hewitt, A. W., Hickey, M., Skinner, R. & Mackey, D., Jul 2018, In : Investigative ophthalmology & visual science. 59, 9, 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2 Citations (Scopus)
Retinal Vein
Retinal Vein Occlusion
Lasers
Randomized Controlled Trials
Macular Edema
2017
2 Citations (Scopus)

A genome-wide scan for microrna-related genetic variants associated with primary open-angle glaucoma

International Glaucoma Genetics Consortium (IGGC) & Mackey, D. A., 1 Oct 2017, In : Investigative Ophthalmology and Visual Science. 58, 12, p. 5368-5377 10 p.

Research output: Contribution to journalArticle

Open Access
MicroRNAs
Genome
Endophenotypes
Primary Open Angle Glaucoma
Genes
8 Citations (Scopus)

Angiopoietin-1 is required for Schlemm’s canal development in mice and humans

Thomson, B. R., Souma, T., Tompson, S. W., Onay, T., Kizhatil, K., Siggs, O. M., Feng, L., Whisenhunt, K. N., Yanovitch, T. L., Kalaydjieva, L., Azmanov, D. N., Finzi, S., Tanna, C. E., Hewitt, A. W., Mackey, D. A., Bradfield, Y. S., Souzeau, E., Javadiyan, S., Wiggs, J. L., Pasutto, F. & 6 othersLiu, X., John, S. W. M., Craig, J. E., Jin, J., Young, T. L. & Quaggin, S. E., 1 Dec 2017, In : Journal of Clinical Investigation. 127, 12, p. 4421-4436 16 p.

Research output: Contribution to journalArticle

Open Access
Angiopoietin-1
Angiopoietins
Glaucoma
Trabecular Meshwork
Aqueous Humor