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Author

  • Michael Millward
2019

A Phase Ib study to assess safety, tolerability, pharmacokinetics, and preliminary antitumor activity of sitravatinib in combination with tislelizumab in patients with advanced solid tumors

Goh, J., Gao, B., Markman, B., Gan, H., Voskoboynik, M., Wu, Y-L., Guo, J., Zhou, Q., Zhao, J., Chen, C., Qiu, J., Xu, Y., Yang, L. & Millward, M., Jul 2019, In : Cancer Research. 79, 13, 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2012
1 Citation (Scopus)
2020

A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer

Sullivan, R. J., Hollebecque, A., Flaherty, K. T., Shapiro, G. I., Rodon Ahnert, J., Millward, M. J., Zhang, W., Gao, L., Sykes, A., Willard, M. D., Yu, D., Schade, A. E., Crowe, K. A., Flynn, D. L., Kaufman, M. D., Henry, J. R., Peng, S. B., Benhadji, K. A., Conti, I., Gordon, M. S. & 2 others, Tiu, R. V. & Hong, D. S., 1 Feb 2020, In : Molecular Cancer Therapeutics. 19, 2, p. 460-467 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Implementation of next generation sequencing technology for somatic mutation detection in routine laboratory practice

Giardina, T., Robinson, C., Grieu-Iacopetta, F., Millward, M., Iacopetta, B., Spagnolo, D. & Amanuel, B., 1 Jun 2018, In : Pathology. 50, 4, p. 389-401 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2014

Patient perception of the benefit of a BRAF inhibitor in metastatic melanoma: Quality-of-life analyses of the BREAK-3 study comparing dabrafenib with dacarbazine

Grob, J. J. R., Amonkar, M. M., Martín-Algarra, S., Demidov, L. V., Goodman, V. L., Grotzinger, K. M., Haney, P., Kämpgen, E., Karaszewska, B., Mauch, C., Miller, J. H., Millward, M., Mirakhur, B., Rutkowski, P., Chiarion Sileni, V., Swann, S. & Hauschild, A., 2014, In : Annals of Oncology. 25, 7, p. 1428-1436

Research output: Contribution to journalArticle

32 Citations (Scopus)

Dose Selection, Pharmacokinetics, and Pharmacodynamics of BRAF inhibitor Dabrafenib (GSK2118436)

Falchook, G. S., Long, G. V., Kurzrock, R., Kim, K. B., Arkenau, H. T., Brown, M. P., Hamid, O., Infante, J. R., Millward, M., Pavlick, A., Chin, M. T., O'Day, S. J., Blackman, S. C., Curtis, C. M., Lebowitz, P., Ma, B., Ouellet, D. & Kefford, R. F., 1 Sep 2014, In : Clinical Cancer Reserach. 20, 17, p. 4449-4458

Research output: Contribution to journalArticle

36 Citations (Scopus)
2013
Open Access
9 Citations (Scopus)
2019

Circulating tumour DNA (ctDNA) as a biomarker in metachronous melanoma and colorectal cancer- a case report

Calapre, L., Warburton, L., Millward, M. & Gray, E. S., 14 Nov 2019, In : BMC Cancer. 19, 1, 1109.

Research output: Contribution to journalArticle

Open Access
2015

Equivocal ALK fluorescence in-situ hybridization (FISH) cases may benefit from ancillary ALK FISH probe testing

Selinger, C., Cooper, W., Lum, T., Mcneil, C., Morey, A., Waring, P., Amanuel, B., Millward, M., Peverall, J., Van Vliet, C., Christie, M., Tran, Y., Diakos, C., Pavlakis, N., Gill, A. J. & O'Toole, S., 2015, In : Histopathology. 67, 5, p. 654-663

Research output: Contribution to journalArticle

12 Citations (Scopus)

PG545 enhances anti-cancer activity of chemotherapy in ovarian models and increases surrogate biomarkers such as VEGF in preclinical and clinical plasma samples

Winterhoff, B., Freyer, L., Hammond, E., Giri, S. S., Mondal, S., Roy, D. K., Teoman, A., Mullany, S. A., Hoffmann, R., Von Bismarck, A., Chien, J., Block, M. S., Millward, M., Bampton, D., Dredge, K. & Shridhar, V., 2015, In : European Journal of Cancer. 51, 7, p. 879-892

Research output: Contribution to journalArticle

34 Citations (Scopus)
2013

Advances in personalized targeted treatment of metastatic melanoma and non-invasive tumor monitoring

Klinac, D., Gray, E. S., Millward, M. & Ziman, M., 2013, In : Frontiers in Oncology. 3, 54, p. 16pp

Research output: Contribution to journalReview article

Open Access
24 Citations (Scopus)
2017

Circulating tumour DNA (ctDNA) as a liquid biopsy for melanoma

Calapre, L., Warburton, L., Millward, M., Ziman, M. & Gray, E. S., 28 Sep 2017, In : Cancer Letters. 404, p. 62-69 8 p.

Research output: Contribution to journalShort survey

Open Access
52 Citations (Scopus)
2020

Role of Serum Vascular Endothelial Growth Factor (VEGF) as a Potential Biomarker of Response to Immune Checkpoint Inhibitor Therapy in Advanced Melanoma: Results of a Pilot Study

Khattak, M. A., Abed, A., Reid, A. L., McEvoy, A. C., Millward, M., Ziman, M. & Gray, E. S., 30 Jun 2020, In : Frontiers in Oncology. 10, 1041.

Research output: Contribution to journalArticle

Open Access
2014

Monitoring changes in circulating tumour cells as a prognostic indicator of overall survival and treatment response in patients with metastatic melanoma

Klinac, D., Gray, E. S., Freeman, J. B., Reid, A. L., Bowyer, S. E., Millward, M. & Ziman, M., 11 Jun 2014, In : BMC Cancer. 14, 1, p. 7pp

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
2012

Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines

Mahoney, S., Arfuso, F., Rogers, P., Hisheh, S., Brown, D., Millward, M. & Dharmarajan, A., 2012, In : Journal of Biosciences. 37, 1, p. 1-12

Research output: Contribution to journalArticle

13 Citations (Scopus)
2013

Phase i study of tremelimumab (CP-675 206) plus PF-3512676 (CPG 7909) in patients with melanoma or advanced solid tumours

Millward, M., Underhill, C., Lobb, S., Mcburnie, J., Meech, S. J., Gomez-Navarro, J., Marshall, M. A., Huang, B. & Mather, C. B., 2013, In : British Journal of Cancer. 108, 10, p. 1998-2004

Research output: Contribution to journalArticle

Open Access
45 Citations (Scopus)
2016

Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy

Bowyer, S., Prithviraj, P., Lorigan, P., Larkin, J., Mcarthur, G., Atkinson, V., Millward, M., Khou, M., Diem, S., Ramanujam, S., Kong, B., Liniker, E., Guminski, A., Parente, P., Andrews, M. C., Parakh, S., Cebon, J., Long, G. V., Carlino, M. S. & Klein, O., 2016, In : British Journal of Cancer. 114, 10, p. 1084-1089

Research output: Contribution to journalArticle

Open Access
56 Citations (Scopus)
2015

BRAF inhibitor dabrafenib in patients with metastatic BRAF-mutant thyroid cancer

Falchook, G., Millward, M., Hong, D., Naing, A., Piha-Paul, S. A., Waguespack, S. G., Cabanillas, M. E., Sherman, S. I., Ma, B., Curtis, M., Goodman, V. L. & Kurzrock, R., 2015, In : Thyroid. 25, 1, p. 71-77

Research output: Contribution to journalArticle

84 Citations (Scopus)
2014

Positive sentinel lymph node metastasis from a metastasis in Melanoma

Bowyer, S. E., Feeney, K. T. & Millward, M., 2014, In : Asia-Pacific Journal of Clinical Oncology. 10, 4, p. 376-377

Research output: Contribution to journalArticle

2012

Role of endobronchial ultrasound in diagnosis and molecular assessment of metastatic melanoma

Jennings, B. R., Millward, M., Amanuel, B., Mulrennan, S., Joosten, S. A. & Phillips, M. J., 2012, In : Respirology. 17, 17, p. 991-996

Research output: Contribution to journalArticle

11 Citations (Scopus)
2018

A Phase i study of the novel immunomodulatory agent PG545 (pixatimod) in subjects with advanced solid tumours

Dredge, K., Brennan, T. V., Hammond, E., Lickliter, J. D., Lin, L., Bampton, D., Handley, P., Lankesheer, F., Morrish, G., Yang, Y., Brown, M. P. & Millward, M., 1 Apr 2018, In : British Journal of Cancer. 118, 8, p. 1035-1041 7 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2012

Serological Biomarkers in Melanoma

Ziman, M., Millward, M., Pearce, R. & Lee, M., 1 Jan 2012, Diagnostic and Prognostic Biomarkers and Therapeutic Targets in Melanoma. Murphy, M. J. (ed.). United States: Springer Dordrecht Heidelberg New York, p. 195-208 14 p.

Research output: Chapter in Book/Conference paperChapter

Efficacy of erlotinib in patients with advanced Non-small-cell Lung Cancer (NSCLC): Analysis of the Australian subpopulation of the TRUST study

Boyer, M., Horwood, K., Pavlakis, N., De Souza, P., Millward, M., Stein, B., Johnston, M., Abell, F. & Rischin, D., 2012, In : Asia-Pacific Journal of Clinical Oncology. 8, p. 248-254

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

Immunotherapy in patients with concurrent solid organ transplant, HIV, and Hepatitis B and C

Rai, R., Ezeoke, O. M., McQuade, J. L., Zimmer, L., Koo, C., Park, J. J., Ardolino, L., Yip, D., Goldinger, S., Cohen, J. V., Millward, M., Atkinson, V., Kane, A. Y., Ascierto, P. A., Garbe, C., Gutzmer, R., Johnson, D. B., Hellman, M. D., Long, G. V. & Menzies, A. M., Sep 2017, In : Annals of Oncology. 28, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2020

Long-term outcomes in patients with BRAF V600-mutant metastatic melanoma receiving dabrafenib monotherapy: Analysis from phase 2 and 3 clinical trials

Hauschild, A., Ascierto, P. A., Schadendorf, D., Grob, J. J., Ribas, A., Kiecker, F., Dutriaux, C., Demidov, L. V., Lebbé, C., Rutkowski, P., Blank, C. U., Gutzmer, R., Millward, M., Kefford, R., Haas, T., D'Amelio, A., Gasal, E., Mookerjee, B. & Chapman, P. B., Jan 2020, In : European Journal of Cancer. 125, p. 114-120 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014
8 Citations (Scopus)
2013

Phase II study of the MEK1/MEK2 inhibitor trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor

Kim, K. B., Kefford, R., Pavlick, A. C., Infante, J. R., Ribas, A., Sosman, J. A., Fecher, L. A., Millward, M., Mcarthur, G. A., Hwu, P., Gonzalez, R., Ott, P. A., Long, G. V., Gardner, O. S., Ouellet, D., Xu, Y., Demarini, D. J., Le, N. T., Patel, K. & Lewis, K. D., 2013, In : Journal of Clinical Oncology. 31, 4, p. 482-489

Research output: Contribution to journalArticle

323 Citations (Scopus)
2019

Safety and antitumor activity of sitravatinib in combination with tislelizumab in patients with advanced solid tumors: Ovarian cancer cohort data

Gao, B., Goh, J., Markman, B., Voskoboynik, M., Gan, H. K., Coward, J., Palmieri, D., So, J., Meniawy, T., Chen, C., Xiang, X., Qiu, J., Xu, Y., Yang, L. & Millward, M., Dec 2019, In : Annals of Oncology. 30, 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2018

A Phase 1B Study of the Anti-PD-1 Monoclonal Antibody, Tislelizumab, in Combination with the Parp Inhibitor, Pamiparib, in Advanced Solid Tumors

Friedlander, M., Meniawy, T., Markman, B., Mileshkin, L. R., Harnett, P., Millward, M., Lundy, J., Freimund, A. E., Norris, C., Wu, J., Paton, V., Wang, L. & Gao, B., Aug 2018, In : Asia-Pacific Journal of Clinical Oncology. 14, p. 58-59 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients

McEvoy, A. C., Warburton, L., Al-Ogaili, Z., Celliers, L., Calapre, L., Pereira, M. R., Khattak, M. A., Meniawy, T. M., Millward, M., Ziman, M. & Gray, E. S., 9 Jul 2018, In : BMC Cancer. 18, 1, 726.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
2017

Liquid biopsies for diagnosis and prognosis of melanoma

Ziman, M., Gray, E., Millward, M., Meniawy, T., Khattak, A. & Zaenker, P., May 2017, In : Australasian Journal of Dermatology. 58, p. 26-27 3 p.

Research output: Contribution to journalAbstract/Meeting Abstract

A Phase II Trial of the Oral FGF Receptor Inhibitor AZD4547 as 2nd or 3rd Line Therapy in Malignant Pleural Mesothelioma - Trial in Progress

Lam, W-S., Lee, Y. C. G., Creaney, J., Muruganandan, S., Millward, M., Read, C. & Nowak, A., Jan 2017, In : Journal of Thoracic Oncology. 12, 1, p. S1087-S1087 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2015

Bleeding Small Intestine Pyogenic Granuloma on 18F-FDG PET/CT

Iravani, A., Law, A., Millward, M., Warner, M. & Sparrow, S., Nov 2015, In : Clinical Nuclear Medicine. 40, 11, p. 869-870 2 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pembrolizumab versus ipilimumab in advanced melanoma

Robert, C., Schachter, J., Long, G. V., Arance, A., Grob, J. J., Mortier, L., Daud, A., Carlino, M. S., McNeil, C., Lotem, M., Larkin, J., Lorigan, P., Neyns, B., Blank, C. U., Hamid, O., Mateus, C., Shapira-Frommer, R., Kosh, M., Zhou, H., Ibrahim, N. & 3 others, Ebbinghaus, S., Ribas, A. & Millward, M., 25 Jun 2015, In : New England Journal of Medicine. 372, 26, p. 2521-2532 12 p.

Research output: Contribution to journalArticle

Open Access
2807 Citations (Scopus)
2018

Anti-PD-1/PD-L1 immunotherapy in patients with solid organ transplant, HIV or hepatitis B/C infection

Tio, M., Rai, R., Ezeoke, O. M., McQuade, J. L., Zimmer, L., Khoo, C., Park, J. J., Spain, L., Turajlic, S., Ardolino, L., Yip, D., Goldinger, S. M., Cohen, J. V., Millward, M., Atkinson, V., Kane, A. Y., Ascierto, P. A., Garbe, C., Gutzmer, R., Johnson, D. B. & 5 others, Rizvi, H. A., Joshua, A. M., Hellmann, M. D., Long, G. V. & Menzies, A. M., Nov 2018, In : European Journal of Cancer. 104, p. 137-144 8 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)
2020

Longitudinal monitoring of ctDNA in patients with melanoma patients and brain metastases treated with immune checkpoint therapy

Lee, J. H., Menzies, A. M., Carlino, M. S., McEvoy, A. C., Sandhu, S., Weppler, A. M., Diefenbach, R. J., Dawson, S-J., Kefford, R. F., Millward, M. J., Al-Ogaili, Z., Tra, T., Gray, E. S., Wong, S. Q., Scolyer, R. A., Long, G. V. & Rizos, H., 22 Apr 2020, In : Clinical Cancer Reserach. PMID 32321716.

Research output: Contribution to journalArticle

2017

Survey of practices around pharmaceutical company funding for continuing professional development among medical oncologists and trainees in Australia

Lee, Y. C., Kroon, R., Koczwara, B., Haines, I., Francis, K., Millward, M., Kefford, R., Olver, I. & Mileshkin, L., 1 Aug 2017, In : Internal Medicine Journal. 47, 8, p. 888-893 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Real-world efficacy and toxicity of combined nivolumab and ipilimumab in patients with metastatic melanoma

Parakh, S., Randhawa, M., Nguyen, B., Warburton, L., Hussain, M. A., Cebon, J., Millward, M., Yip, D. & Ali, S., 13 Nov 2018, In : Asia–Pacific Journal of Clinical Oncology.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2014

Tecemotide (L-BLP25) versus placebo after chemoradiotherapy for stage III non-small-cell lung cancer (START): A randomised, double-blind, phase 3 trial

Butts, C., Socinski, M. A., Mitchell, P. L., Thatcher, N., Havel, L., Krzakowski, M., Nawrocki, S., Ciuleanu, T. E., Bosquée, L., Trigo, J. M., Spira, A., Tremblay, L., Nyman, J., Ramlau, R., Wickart-Johansson, G., Ellis, P., Gladkov, O., Pereira, J. R., Eberhardt, W. E. E., Helwig, C. & 3 others, Schröder, A., Shepherd, F. A. & Millward, M., 1 Jan 2014, In : LANCET ONCOLOGY. 15, 1, p. 59-68 10 p., PMID 24331154.

Research output: Contribution to journalArticle

266 Citations (Scopus)
2020

A comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma

Nguyen, B., Meehan, K., Pereira, M. R., Mirzai, B., Lim, S. H., Leslie, C., Clark, M., Sader, C., Friedland, P., Lindsay, A., Tang, C., Millward, M., Gray, E. S. & Lim, A. M., 1 Dec 2020, In : Scientific Reports. 10, 1, 6083.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2017

Isolation and detection of circulating tumour cells from metastatic melanoma patients using a slanted spiral microfluidic device

Aya-Bonilla, C. A., Marsavela, G., Freeman, J. B., Lomma, C., Frank, M. H., Khattak, M. A., Meniawy, T. M., Millward, M., Warkiani, M. E., Gray, E. S. & Ziman, M., 15 Sep 2017, In : Oncotarget. 8, 40, p. 67355-67368 14 p.

Research output: Contribution to journalArticle

Open Access

Treatment of ALK-rearranged non-small cell lung cancer: A review of the landscape and approach to emerging patterns of treatment resistance in the Australian context

Itchins, M., Chia, P. L., Hayes, S. A., Howell, V. M., Gill, A. J., Cooper, W. A., John, T., Mitchell, P., Millward, M., Clarke, S. J., Solomon, B. & Pavlakis, N., 1 Aug 2017, In : Asia-Pacific Journal of Clinical Oncology. 13, p. 3-13 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2020

Detection and prognostic role of heterogeneous populations of melanoma circulating tumour cells

Aya-Bonilla, C. A., Morici, M., Hong, X., McEvoy, A. C., Sullivan, R. J., Freeman, J., Calapre, L., Khattak, M. A., Meniawy, T., Millward, M., Ziman, M. & Gray, E. S., 31 Mar 2020, In : British Journal of Cancer. 122, 7, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

2015
35 Citations (Scopus)
2019

PD-L1 Expression on Circulating Tumor Cells May Be Predictive of Response to Pembrolizumab in Advanced Melanoma: Results from a Pilot Study

Khattak, M. A., Reid, A., Freeman, J., Pereira, M., McEvoy, A., Lo, J., Frank, M. H., Meniawy, T., Didan, A., Spencer, I., Amanuel, B., Millward, M., Ziman, M. & Gray, E., 5 Dec 2019, In : The Oncologist.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2014

Wnt Antagonist, Secreted Frizzled-Related Protein 4 (sFRP4), Increases Chemotherapeutic Response of Glioma Stem-Like Cells

Warrier, S., Balu, S. K., Kumar, A., Millward, M. & Dharmarajan, A., 2014, In : Oncology Research. 21, p. 93-102

Research output: Contribution to journalArticle

41 Citations (Scopus)
2017

Clinical and therapeutic implications of BRAF mutation heterogeneity in metastatic melanoma

Mesbah Ardakani, N., Leslie, C., Grieu-Iacopetta, F., Lam, W. S., Budgeon, C., Millward, M. & Amanuel, B., 1 Mar 2017, In : Pigment Cell and Melanoma Research. 30, 2, p. 233-242

Research output: Contribution to journalArticle

9 Citations (Scopus)