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Publication Year

  • 2020
  • 2019
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Author

  • Mark Nicol
Article

Improving the design of studies evaluating the impact of diagnostic tests for tuberculosis on health outcomes: a qualitative study of perspectives of diverse stakeholders

Ochodo, E. A., Naidoo, S., Schumacher, S., Steingart, K., Deeks, J., Cobelens, F., Bossuyt, P. M., Young, T. & Nicol, M. P., 21 Nov 2019, In : Wellcome Open Research. 4, p. 183

Research output: Contribution to journalArticle

Open Access

Incidence and diagnosis of pertussis in South African children hospitalized with lower respiratory tract infection

Muloiwa, R., Dube, F. S., Nicol, M. P., Zar, H. J. & Hussey, G. D., 10 Mar 2016, In : Pediatric Infectious Disease Journal. 35, 6, p. 611-616 6 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study

Vanker, A., Nduru, P. M., Barnett, W., Dube, F. S., Sly, P. D., Gie, R. P., Nicol, M. P. & Zar, H. J., Feb 2019, In : ERJ Open Research. 5, 1, 2 p.

Research output: Contribution to journalArticle

Open Access

Influence of Socio-Economic and Psychosocial Profiles on the Human Breast Milk Bacteriome of South African Women

Ojo-Okunola, A., Claassen-Weitz, S., Mwaikono, K. S., Gardner-Lubbe, S., Stein, D. J., Zar, H. J., Nicol, M. P. & du Toit, E., 20 Jun 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Integrating environmental health and genomics research in Africa: challenges and opportunities identified during a Human Heredity and Health in Africa (H3Africa) Consortium workshop

Joubert, B. R., Berhane, K., Chevrier, J., Collman, G., Eskenazi, B., Fobil, J., Hoyo, C., John, C. C., Kumie, A., Nicol, M., Ramsay, M., Smith, J., Steyn, A., Tshala-Katumbay, D. & McAllister, K., Aug 2019, In : Gates Open Research. 2, p. 159

Research output: Contribution to journalArticle

Open Access

Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: Phenotypic and genotypic analysis of isolates

GERMS-SA Surveillance Network & Nicol, M., 29 Sep 2017, In : BMC Infectious Diseases. 17, 1, 9 p., 656.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing

Manenzhe, R. I., Dube, F. S., Wright, M., Lennard, K., Zar, H. J., Mounaud, S., Nierman, W. C., Nicol, M. P. & Moodley, C., 2020, In : PLoS One. 15, 4, p. e0231887

Research output: Contribution to journalArticle

Open Access

Longitudinal characterization of nasopharyngeal colonization with Streptococcus pneumoniae in a South African birth cohort post 13-valent pneumococcal conjugate vaccine implementation

Dube, F. S., Ramjith, J., Gardner-Lubbe, S., Nduru, P., Robberts, F. J. L., Wolter, N., Zar, H. J. & Nicol, M. P., 1 Dec 2018, In : Scientific Reports. 8, 1, 12497.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Longitudinal Population Dynamics of Staphylococcus aureus in the Nasopharynx During the First Year of Life

Abdulgader, S. M., Robberts, L., Ramjith, J., Nduru, P. M., Dube, F., Gardner-Lubbe, S., Zar, H. J. & Nicol, M. P., 15 Mar 2019, In : Frontiers in Genetics. 10, 10 p., 198.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Management of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 3)

Reubenson, G., Avenant, T., Moore, D. P., Itzikowitz, G., Andronikou, S., Cohen, C., Green, R. J., Jeena, P., Masekela, R., Nicol, M. P., Pillay, A., Madhi, S. A., Zar, H. J. & Argent, A. C., Aug 2020, In : South African Medical Journal. 110, 8, p. 734-740 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Microbiological diagnosis of pulmonary tuberculosis in children by oral swab polymerase chain reaction

Nicol, M. P., Wood, R. C., Workman, L., Prins, M., Whitman, C., Ghebrekristos, Y., Mbhele, S., Olson, A., Jones-Engel, L. E., Zar, H. J. & Cangelosi, G. A., 25 Jul 2019, In : Scientific Reports. 9, 1, p. 10789

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Multicenter Study of the Accuracy of the BD MAX™ MDR-TB Assay for Detection of Mycobacterium tuberculosis Complex and Mutations Associated with Resistance to Rifampin and Isoniazid

Shah, M., Paradis, S., Betz, J., Beylis, N., Bharadwaj, R., Caceres, T., Gotuzzo, E., Joloba, M., Mave, V., Nakiyingi, L., Nicol, M. P., Pradhan, N., King, B., Armstrong, D., Knecht, D., Maus, C. E., Cooper, C. K., Dorman, S. E. & Manabe, Y. C., 27 Sep 2019, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalArticle

Open Access
File

Nasopharyngeal carriage of antimicrobial-resistant pneumococci in an intensively sampled South African birth cohort

Manenzhe, R., Moodley, C., Abdulgader, S. M., Robberts, F. J. L., Zar, H. J., Nicol, M. P. & Dube, F. S., 27 Mar 2019, In : Frontiers in Microbiology. 10, 10 p., 610.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study

Broger, T., Sossen, B., du Toit, E., Kerkhoff, A. D., Schutz, C., Ivanova Reipold, E., Ward, A., Barr, D. A., Macé, A., Trollip, A., Burton, R., Ongarello, S., Pinter, A., Lowary, T. L., Boehme, C., Nicol, M. P., Meintjes, G. & Denkinger, C. M., 30 May 2019, In : The Lancet Infectious Diseases. 10 p.

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

Optimizing 16S rRNA gene profile analysis from low biomass nasopharyngeal and induced sputum specimens

Claassen-Weitz, S., Gardner-Lubbe, S., Mwaikono, K. S., du Toit, E., Zar, H. J. & Nicol, M. P., 12 May 2020, In : BMC Microbiology. 20, 1, 26 p., 113.

Research output: Contribution to journalArticle

Open Access

Optimizing Tuberculosis Diagnosis in Human Immunodeficiency Virus-Infected Inpatients Meeting the Criteria of Seriously Ill in the World Health Organization Algorithm

Griesel, R., Stewart, A., van der Plas, H., Sikhondze, W., Rangaka, M. X., Nicol, M. P., Kengne, A. P., Mendelson, M. & Maartens, G., 6 Nov 2017, In : Clinical Infectious Diseases. 66, 9, p. 1419-1426 8 p.

Research output: Contribution to journalArticle

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa

Kalule, J. B., Smith, A. M., Vulindhlu, M., Tau, N. P., Nicol, M. P., Keddy, K. H. & Robberts, L., 6 Nov 2019, In : BMC Microbiology. 19, 1, 244.

Research output: Contribution to journalArticle

Open Access

Prevention of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 4)

Zar, H. J., Moore, D. P., Andronikou, S., Argent, A. C., Avenant, T., Cohen, C., Green, R. J., Itzikowitz, G., Jeena, P., Nicol, M. P., Pillay, A., Reubenson, G., Masekela, R. & Madhi, S. A., Aug 2020, In : South African Medical Journal. 110, 8, p. 741-746 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Proteomic comparison of three clinical diarrhoeagenic drug-resistant Escherichia coli isolates grown on CHROMagar™STEC media

Kalule, J. B., Fortuin, S., Calder, B., Robberts, L., Keddy, K. H., Nel, A. J. M., Garnett, S., Nicol, M., Warner, D. F., Soares, N. C. & Blackburn, J. M., 30 May 2018, In : Journal of Proteomics. 180, p. 25-35 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Recent developments in the diagnosis of drug-resistant tuberculosis

Nicol, M. P. & Cox, H., 1 Jan 2019, In : Microbiology Australia. 40, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

Regulatory T cells and pro-inflammatory responses predominate in children with tuberculosis

Whittaker, E., Nicol, M., Zar, H. J. & Kampmann, B., 25 Apr 2017, In : Frontiers in Immunology. 8, APR, 448.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa

Dube, F. S., Kaba, M., Robberts, F. J. L., Tow, L. A., Lubbe, S., Zar, H. J. & Nicol, M. P., 24 Oct 2016, In : BMC Infectious Diseases. 16, 1, 12 p., 597.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Serologic Responses in Childhood Pulmonary Tuberculosis

Nonyane, B. A. S., Nicol, M. P., Andreas, N. J., Rimmele, S., Schneiderhan-Marra, N., Workman, L. J., Perkins, M. D., Joos, T., Broger, T., Ellner, J. J., Alland, D., Kampmann, B., Dorman, S. E. & Zar, H. J., 1 Jan 2018, In : Pediatric Infectious Disease Journal. 37, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra

Zar, H. J. & Nicol, M. P., 1 Nov 2019, In : Pediatrics. 144, 5

Research output: Contribution to journalArticle

1 Citation (Scopus)

The Influence of DNA Extraction and Lipid Removal on Human Milk Bacterial Profiles

Ojo-Okunola, A., Claassen-Weitz, S., Mwaikono, K. S., Gardner-Lubbe, S., Zar, H. J., Nicol, M. P. & du Toit, E., 15 May 2020, In : Methods and protocols. 3, 2

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

The Influence of HIV on the Evolution of Mycobacterium tuberculosis

Koch, A. S., Brites, D., Stucki, D., Evans, J. C., Seldon, R., Heekes, A., Mulder, N., Nicol, M., Oni, T., Mizrahi, V., Warner, D. F., Parkhill, J., Gagneux, S., Martin, D. P. & Wilkinson, R. J., 1 Jul 2017, In : Molecular Biology and Evolution. 34, 7, p. 1654-1668 15 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Tuberculin skin test conversion and primary progressive tuberculosis disease in the first 5 years of life: a birth cohort study from Cape Town, South Africa

Martinez, L., le Roux, D. M., Barnett, W., Stadler, A., Nicol, M. P. & Zar, H. J., 1 Jan 2018, In : The Lancet Child & Adolescent Health. 2, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)

Tuberculosis Diagnosis in Children Using Xpert Ultra on Different Respiratory Specimens

Zar, H. J., Workman, L. J., Prins, M., Bateman, L. J., Mbhele, S. P., Whitman, C. B., Denkinger, C. M. & Nicol, M. P., 15 Dec 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 12, p. 1531-1538

Research output: Contribution to journalArticle

11 Citations (Scopus)

Tuberculosis diagnostics: State of the art and future directions

Pai, M., Nicol, M. P. & Boehme, C. C., 1 Jan 2016, In : Microbiology Spectrum. 4, 5, TBTB2-0019-2016.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

Utility of second-generation line probe assay (Hain MTBDRplus) directly on 2-month sputum specimens for monitoring tuberculosis treatment response

Rockwood, N., Wojno, J., Ghebrekristos, Y., Nicol, M. P., Meintjes, G. & Wilkinson, R. J., 1 May 2017, In : Journal of Clinical Microbiology. 55, 5, p. 1508-1515 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations?

Hanifa, Y., Toro Silva, S., Karstaedt, A., Sahid, F., Charalambous, S., Chihota, V. N., Churchyard, G. J., von Gottberg, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Stevens, W., Fielding, K. L. & Grant, A. D., 1 Feb 2019, In : International Journal of Tuberculosis & Lung Disease. 23, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Dorman, S. E., Schumacher, S. G., Alland, D., Nabeta, P., Armstrong, D. T., King, B., Hall, S. L., Chakravorty, S., Cirillo, D. M., Tukvadze, N., Bablishvili, N., Stevens, W., Scott, L., Rodrigues, C., Kazi, M. I., Joloba, M., Nakiyingi, L., Nicol, M. P., Ghebrekristos, Y., Anyango, I. & 12 others, Murithi, W., Dietze, R., Lyrio Peres, R., Skrahina, A., Auchynka, V., Chopra, K. K., Hanif, M., Liu, X., Yuan, X., Boehme, C. C., Ellner, J. J. & Denkinger, C. M., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Open Access
165 Citations (Scopus)
Comment/debate

Current knowledge and future research directions on fecal bacterial patterns and their association with asthma

Claassen-Weitz, S., Wiysonge, C. S., Machingaidze, S., Thabane, L., Horsnell, W. G. C., Zar, H. J., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, JUN, 838.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Genome sequence for shiga toxin- producing Escherichia coli O26: H11, associated with a cluster of hemolytic- uremic syndrome cases in South Africa, 2017

Smith, A. M., Bosco, K. J., Nicol, M. P., Kleynhans, J., McCulloch, M., Duze, S. T., Ismail, A., Allam, M., Tau, N. P. & Keddy, K. H., 1 Sep 2017, In : Genome Announcements. 5, 38, e00989-17.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Preventing tuberculosis-related death in children with HIV

Tootla, H. D. & Nicol, M. P., 1 Feb 2018, In : The lancet. HIV. 5, 2, p. e62-e64

Research output: Contribution to journalComment/debate

Remembering the basics: interventions to improve sputum collection for tuberculosis diagnosis

Centner, C. M. & Nicol, M. P., 1 Aug 2017, In : The Lancet Global Health. 5, 8, p. e728-e729

Research output: Contribution to journalComment/debate

Treatment of bronchiectasis exacerbations in children: which antibiotic?

Zar, H. J. & Nicol, M. P., 6 Oct 2018, In : The Lancet. 392, 10154, p. 1169-1170 2 p.

Research output: Contribution to journalComment/debate

Tuberculosis eradication: renewed commitment and global investment required

Cox, H. & Nicol, M. P., 1 Mar 2018, In : The Lancet Infectious Diseases. 18, 3, p. 228-229 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Khonga, M. & Nicol, M. P., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 6-8 3 p.

Research output: Contribution to journalComment/debate

8 Citations (Scopus)
Editorial

Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

Kerkhoff, A. D., Sossen, B., Schutz, C., Reipold, E. I., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Nicol, M. P., Meintjes, G., Denkinger, C. M. & Broger, T., 7 Nov 2019, In : The European Respiratory Journal.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

How should tuberculosis molecular diagnostics be adapted for use in seriously ill HIV patients?

Nicol, M. P., 1 Dec 2016, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 16, 12, p. 1237-1239 3 p.

Research output: Contribution to journalEditorial

Key advances and remaining challenges in childhood and adolescent tuberculosis

Marais, B. J., Nicol, M. & Zar, H. J., 2020, In : Paediatric Respiratory Reviews.

Research output: Contribution to journalEditorial

Letter

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 2 Mar 2020, In : BMC Infectious Diseases. 20, 1, p. 187

Research output: Contribution to journalLetter

Open Access
Review article

Advances in the diagnosis of pneumonia in children

Zar, H. J., Andronikou, S. & Nicol, M. P., 26 Jul 2017, In : BMJ (Online). 358, j2739.

Research output: Contribution to journalReview article

19 Citations (Scopus)

Advances in the diagnosis of pulmonary tuberculosis in children

Nicol, M. P. & Zar, H. J., 25 May 2020, In : Paediatric Respiratory Reviews.

Research output: Contribution to journalReview article

Fecal carriage of Staphylococcus aureus in the hospital and community setting: A systematic review

Claassen-Weitz, S., Shittu, A. O., Ngwarai, M. R., Thabane, L., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, MAY, 449.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)

Human breast milk bacteriome in health and disease

Ojo-Okunola, A., Nicol, M. & du Toit, E., 3 Nov 2018, In : Nutrients. 10, 11, 1643.

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)

Precision medicine for drug-resistant tuberculosis in high-burden countries: is individualised treatment desirable and feasible?

Cox, H., Hughes, J., Black, J. & Nicol, M. P., 1 Sep 2018, In : The Lancet Infectious Diseases. 18, 9, p. e282-e287

Research output: Contribution to journalReview article

17 Citations (Scopus)