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Author

  • Mark Nicol

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

RSV Global Epidemiology Network & RESCEU Investigators, Aug 2019, In : The Lancet Global Health. 7, 8, p. E1031-E1045 15 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Shi, T., McAllister, D. A., O'Brien, K. L., Simoes, E. A. F., Madhi, S. A., Gessner, B. D., Polack, F. P., Balsells, E., Acacio, S., Aguayo, C., Alassani, I., Ali, A., Antonio, M., Awasthi, S., Awori, J. O., Azziz-Baumgartner, E., Baggett, H. C., Baillie, V. L., Balmaseda, A., Barahona, A. & 102 others, Basnet, S., Bassat, Q., Basualdo, W., Bigogo, G., Bont, L., Breiman, R. F., Brooks, W. A., Broor, S., Bruce, N., Bruden, D., Buchy, P., Campbell, S., Carosone-Link, P., Chadha, M., Chipeta, J., Chou, M., Clara, W., Cohen, C., de Cuellar, E., Dang, D. A., Dash-yandag, B., Deloria-Knoll, M., Dherani, M., Eap, T., Ebruke, B. E., Echavarria, M., de Freitas Lázaro Emediato, C. C., Fasce, R. A., Feikin, D. R., Feng, L., Gentile, A., Gordon, A., Goswami, D., Goyet, S., Groome, M., Halasa, N., Hirve, S., Homaira, N., Howie, S. R. C., Jara, J., Jroundi, I., Kartasasmita, C. B., Khuri-Bulos, N., Kotloff, K. L., Krishnan, A., Libster, R., Lopez, O., Lucero, M. G., Lucion, F., Lupisan, S. P., Marcone, D. N., McCracken, J. P., Mejia, M., Moisi, J. C., Montgomery, J. M., Moore, D. P., Moraleda, C., Moyes, J., Munywoki, P., Mutyara, K., Nicol, M. P., Nokes, D. J., Nymadawa, P., da Costa Oliveira, M. T., Oshitani, H., Pandey, N., Paranhos-Baccalà, G., Phillips, L. N., Picot, V. S., Rahman, M., Rakoto-Andrianarivelo, M., Rasmussen, Z. A., Rath, B. A., Robinson, A., Romero, C., Russomando, G., Salimi, V., Sawatwong, P., Scheltema, N., Schweiger, B., Scott, J. A. G., Seidenberg, P., Shen, K., Singleton, R., Sotomayor, V., Strand, T. A., Sutanto, A., Sylla, M., Tapia, M. D., Thamthitiwat, S., Thomas, E. D., Tokarz, R., Turner, C., Venter, M., Waicharoen, S., Wang, J., Watthanaworawit, W., Yoshida, L. M., Yu, H., Zar, H. J., Campbell, H. & Nair, H., 2 Sep 2017, In : The Lancet. 390, 10098, p. 946-958 13 p.

Research output: Contribution to journalArticle

Open Access
427 Citations (Scopus)

Genome sequence for shiga toxin- producing Escherichia coli O26: H11, associated with a cluster of hemolytic- uremic syndrome cases in South Africa, 2017

Smith, A. M., Bosco, K. J., Nicol, M. P., Kleynhans, J., McCulloch, M., Duze, S. T., Ismail, A., Allam, M., Tau, N. P. & Keddy, K. H., 1 Sep 2017, In : Genome Announcements. 5, 38, e00989-17.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

Breen, M. S., Wingo, A. P., Koen, N., Donald, K. A., Nicol, M., Zar, H. J., Ressler, K. J., Buxbaum, J. D. & Stein, D. J., 1 Oct 2018, In : Brain, Behavior, and Immunity. 73, p. 320-330 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis

Nabeta, P., Seshadri, P., Havumaki, J., Mbhele, S., Hendricks, L., Perkins, M. D., Nicol, M. P. & Denkinger, C. M., 19 Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 115026.

Research output: Contribution to journalArticle

Open Access

Fecal carriage of Staphylococcus aureus in the hospital and community setting: A systematic review

Claassen-Weitz, S., Shittu, A. O., Ngwarai, M. R., Thabane, L., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, MAY, 449.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

Schutz, C., Ward, A., Burton, R., Nicol, M. P., Blumenthal, U., Meintjes, G. & Kerkhoff, A. D., 28 Aug 2019, In : Southern African Journal of HIV Medicine. 20, 1, 10 p., 978.

Research output: Contribution to journalArticle

Open Access

Epidemiology and aetiology of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 1)

Moore, D. P., Green, R. J., Cohen, C., Itzikowitz, G., Andronikou, S., Argent, A. C., Avenant, T., Jeena, P., Masekela, R., Nicol, M. P., Pillay, A., Reubenson, G., Madhi, S. A. & Zar, H. J., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 583-587 5 p.

Research output: Contribution to journalArticle

Open Access

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis

Di Tanna, G. L., Raza Khaki, A., Theron, G., McCarthy, K., Cox, H., Mupfumi, L., Trajman, A., Sodai Zijenah, L., Mason, P., Bandason, T., Durovni, B., Bara, W., Hoelscher, M., Clowes, P., Mangu, C., Chanda, D., Pym, A., Mwaba, P., Cobelens, F., Nicol, M. P. & 4 others, Dheda, K., Churchyard, G., Fielding, K. & Metcalfe, J. Z., 1 Feb 2019, In : The Lancet Global Health. 7, 2, p. e191-e199

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Drug-resistant tuberculosis patient care journeys in South Africa: a pilot study using routine laboratory data

Hill, J., Dickson-Hall, L., Grant, A. D., Grundy, C., Black, J., Kielmann, K., Mlisana, K., Mitrani, L., Loveday, M., Moshabela, M., Le Roux, S., Jassat, W., Nicol, M. & Cox, H., 1 Jan 2020, In : International Journal of Tuberculosis & Lung Disease. 24, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Open Access

Distinct patterns in human milk microbiota and fatty acid profiles across specific geographic locations

Kumar, H., du Toit, E., Kulkarni, A., Aakko, J., Linderborg, K. M., Zhang, Y., Nicol, M. P., Isolauri, E., Yang, B., Collado, M. C. & Salminen, S., 13 Oct 2016, In : Frontiers in Microbiology. 7, OCT, 1619.

Research output: Contribution to journalArticle

Open Access
76 Citations (Scopus)

Disseminated tuberculosis among hospitalised HIV patients in South Africa: A common condition that can be rapidly diagnosed using urine-based assays

Kerkhoff, A. D., Barr, D. A., Schutz, C., Burton, R., Nicol, M. P., Lawn, S. D. & Meintjes, G., 1 Dec 2017, In : Scientific Reports. 7, 1, 10931.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)

Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region

Tomasicchio, M., Limberis, J., van der Merwe, R., Jacobson, R., Meldau, R., Theron, G., Nicol, M., Warren, R. & Dheda, K., 1 Jul 2020, In : International Journal of Infectious Diseases. 96, p. 240-243

Research output: Contribution to journalArticle

Open Access

Diagnostic Test Accuracy in Childhood Pulmonary Tuberculosis: A Bayesian Latent Class Analysis

Schumacher, S. G., Van Smeden, M., Dendukuri, N., Joseph, L., Nicol, M. P., Pai, M. & Zar, H. J., 1 Nov 2016, In : American Journal of Epidemiology. 184, 9, p. 690-700 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

Kerkhoff, A. D., Sossen, B., Schutz, C., Reipold, E. I., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Nicol, M. P., Meintjes, G., Denkinger, C. M. & Broger, T., 7 Nov 2019, In : The European Respiratory Journal.

Research output: Contribution to journalEditorial

Diagnostic limitations of clinical case definitions of pertussis in infants and children with severe lower respiratory tract infection

Muloiwa, R., Nicol, M. P., Hussey, G. D. & Zar, H. J., 17 Jul 2020, In : PLoS One. 15, 7, p. e0235703

Research output: Contribution to journalArticle

Open Access

Diagnostic accuracy of two multiplex real-Time polymerase chain reaction assays for the diagnosis of meningitis in children in a resource-limited setting

Khumalo, J., Nicol, M., Hardie, D., Muloiwa, R., Mteshana, P. & Bamford, C., 1 Mar 2017, In : PLoS One. 12, 3, e0173948.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Diagnostic accuracy of three urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients

Broger, T., Nicol, M., Sigal, G., Gotuzzo, E., Zimmer, A. J., Surtie, S., Caceres-Nakiche, T., Mantsoki, A., Reipold, E. I., Székely, R., Tsionsky, M., van Heerden, J., Plisova, T., Chikamatsu, K., Lowary, T. L., Pinter, A., Mitarai, S., Moreau, E., Schumacher, S. G. & Denkinger, C. M., 21 Jul 2020, In : The Journal of clinical investigation.

Research output: Contribution to journalArticle

Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 13 Jan 2020, In : BMC Infectious Diseases. 20, 1, p. 33

Research output: Contribution to journalArticle

Open Access

Diagnostic accuracy of lateral flow urine LAM assay for TB screening of adults with advanced immunosuppression attending routine HIV care in South Africa

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Karstaedt, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Sahid, F., Churchyard, G. J. & Grant, A. D., 1 Jun 2016, In : PLoS One. 11, 6, e0156866.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data

Broger, T., Nicol, M. P., Székely, R., Bjerrum, S., Sossen, B., Schutz, C., Opintan, J. A., Johansen, I. S., Mitarai, S., Chikamatsu, K., Kerkhoff, A. D., Macé, A., Ongarello, S., Meintjes, G., Denkinger, C. M. & Schumacher, S. G., May 2020, In : PLoS Medicine. 17, 5, p. e1003113

Research output: Contribution to journalArticle

Open Access

Diagnostic accuracy, incremental yield and prognostic value of Determine TB-LAM for routine diagnostic testing for tuberculosis in HIV-infected patients requiring acute hospital admission in South Africa: A prospective cohort

Lawn, S. D., Kerkhoff, A. D., Burton, R., Schutz, C., Boulle, A., Vogt, M., Gupta-Wright, A., Nicol, M. P. & Meintjes, G., 21 Mar 2017, In : BMC Medicine. 15, 1, 67.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)

Diagnosis of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 2)

Zar, H. J., Moore, D. P., Itzikowitz, G., Green, R. J., Argent, A. C., Avenant, T., Cohen, C., Jeena, P., Masekela, R., Pillay, A., Reubenson, G., Madhi, S. A., Andronikou, S. & Nicol, M. P., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 588-593 6 p.

Research output: Contribution to journalArticle

Development of a real-time PCR assay and comparison to CHROMagar (TM) STEC to screen for Shiga toxin-producing Escherichia coli in stool, Cape Town, South Africa

Kalule, J. B., Keddy, K. H., Smith, A., Nicol, M. P. & Robberts, L., 14 Dec 2017, In : African journal of laboratory medicine. 6, 1, 8 p., 609.

Research output: Contribution to journalArticle

Open Access

Development of a clinical prediction rule to diagnose Pneumocystis jirovecii pneumonia in the World Health Organization's algorithm for seriously ill HIV-infected patients

Maartens, G., Stewart, A., Griesel, R., Kengne, A. P., Dube, F., Nicol, M., Rangaka, M. X. & Mendelson, M., 2018, In : Southern African Journal of HIV Medicine. 19, 1, p. 851

Research output: Contribution to journalArticle

Open Access

Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study

Cox, H., Dickson-Hall, L., Ndjeka, N., van’t Hoog, A., Grant, A., Cobelens, F., Stevens, W. & Nicol, M., 1 Feb 2017, In : PLoS Medicine. 14, 2, e1002238.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)

Current knowledge and future research directions on fecal bacterial patterns and their association with asthma

Claassen-Weitz, S., Wiysonge, C. S., Machingaidze, S., Thabane, L., Horsnell, W. G. C., Zar, H. J., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, JUN, 838.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 2 Mar 2020, In : BMC Infectious Diseases. 20, 1, p. 187

Research output: Contribution to journalLetter

Open Access

Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe

Breathe Study Team, 14 Jan 2020, In : The Journal of infectious diseases. 221, 3, p. 483-492

Research output: Contribution to journalArticle

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Schutz, C., Barr, D., Andrade, B. B., Shey, M., Ward, A., Janssen, S., Burton, R., Wilkinson, K. A., Sossen, B., Fukutani, K. F., Nicol, M., Maartens, G., Wilkinson, R. J. & Meintjes, G., Jul 2019, In : PLoS Medicine. 16, 7, p. e1002840

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Chronic lung disease in children and adolescents with HIV: a case–control study

the BREATHE Clinical Trial Team, 1 Jan 2020, In : Tropical Medicine and International Health.

Research output: Contribution to journalArticle

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function

Hemingway, C., Berk, M., Anderson, S. T., Wright, V. J., Hamilton, S., Eleftherohorinou, H., Kaforou, M., Goldgof, G. M., Hickman, K., Kampmann, B., Schoeman, J., Eley, B., Beatty, D., Pienaar, S., Nicol, M. P., Griffiths, M. J., Waddell, S. J., Newton, S. M., Coin, L. J., Relman, D. A. & 2 others, Montana, G. & Levin, M., 1 Nov 2017, In : PLoS One. 12, 11, e0185973.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Characterisation of STEC and other diarrheic E. coli isolated on CHROMagar™STEC at a tertiary referral hospital, Cape Town

Kalule, J. B., Keddy, K. H. & Nicol, M. P., 8 Jun 2018, In : BMC Microbiology. 18, 1, 55.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Carriage of extended-spectrum beta-lactamase-producing enterobacteriaceae in HIV-infected children in Zimbabwe

Wilmore, S. M. S., Kranzer, K., Williams, A., Makamure, B., Nhidza, A. F., Mayini, J., Bandason, T., Metcalfe, J., Nicol, M. P., Balakrishnan, I., Ellington, M. J., Woodford, N., Hopkins, S., McHugh, T. D. & Ferrand, R. A., 1 May 2017, In : Journal of Medical Microbiology. 66, 5, p. 609-615 7 p., 000474.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center

Van Hoving, D. J., Lahri, S., Lategan, H. J., Nicol, M. P., Maartens, G. & Meintjes, G., 1 May 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 1, p. e10-e14

Research output: Contribution to journalArticle

1 Citation (Scopus)

Blood and virus detection on barber clippers

Spengane, Z., Korsman, S., Mkentane, K., Davids, L. M., Zemanay, W., Africa, M., Mbhele, S., Nicol, M., Gumedze, F., Ngwanya, D. & Khumalo, N. P., 1 Apr 2018, In : South African Medical Journal. 108, 4, p. 278-282 5 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access
5 Citations (Scopus)

"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa

Furin, J., Loveday, M., Hlangu, S., Dickson-Hall, L., le Roux, S., Nicol, M. & Cox, H., 17 Jan 2020, In : BMC Public Health. 20, 1, 76.

Research output: Contribution to journalArticle

Open Access

A survey of tuberculosis infection control practices at the NIH/NIAID/DAIDS-supported clinical trial sites in low and middle income countries

HIV Network Coordinating (HANC) TB Diagnostic Laboratory Working Division of AIDS, National Institute of Allergy and Infectious Diseases, 10 Jun 2016, In : BMC Infectious Diseases. 16, 1, 7 p., 269.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile

Naudé, P. J. W., Claassen-Weitz, S., Gardner-Lubbe, S., Botha, G., Kaba, M., Zar, H. J., Nicol, M. P. & Stein, D. J., 22 Nov 2019, In : Acta Neuropsychiatrica. p. 1-31 31 p.

Research output: Contribution to journalArticle

Open Access
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Analytical and clinical evaluation of the epistem genedrive assay for detection of mycobacterium tuberculosis

Shenai, S., Armstrong, D. T., Valli, E., Dolinger, D. L., Nakiyingi, L., Dietze, R., Dalcolmo, M. P., Nicol, M. P., Zemanay, W., Manabe, Y., Hadad, D. J., Marques-Rodrigues, P., Palaci, M., Peres, R. L., Gaeddert, M., Armakovitch, S., Nonyane, B. A. S., Denkinger, C. M., Banada, P., Joloba, M. L. & 4 others, Ellner, J., Boehme, C., Alland, D. & Dorman, S. E., 1 Apr 2016, In : Journal of Clinical Microbiology. 54, 4, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Age-related waning of immune responses to BCG in healthy children supports the need for a booster dose of BCG in TB endemic countries

Whittaker, E., Nicol, M. P., Zar, H. J., Tena-Coki, N. G. & Kampmann, B., 1 Dec 2018, In : Scientific Reports. 8, 1, 15309.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: A nested case-control study of the Drakenstein Child Health Study

Zar, H. J., Barnett, W., Stadler, A., Gardner-Lubbe, S., Myer, L. & Nicol, M. P., 1 Jun 2016, In : The Lancet Respiratory Medicine. 4, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

Open Access
63 Citations (Scopus)

Advances in the diagnosis of pulmonary tuberculosis in children

Nicol, M. P. & Zar, H. J., 25 May 2020, In : Paediatric Respiratory Reviews.

Research output: Contribution to journalReview article

Advances in the diagnosis of pneumonia in children

Zar, H. J., Andronikou, S. & Nicol, M. P., 26 Jul 2017, In : BMJ (Online). 358, j2739.

Research output: Contribution to journalReview article

18 Citations (Scopus)

A clinical scoring system to prioritise investigation for tuberculosis among adults attending HIV clinics in South Africa

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Foster, N., Karstaedt, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Sinanovic, E., Sahid, F., Stevens, W., Vassall, A., Churchyard, G. J. & Grant, A. D., 1 Aug 2017, In : PLoS One. 12, 8, e0181519.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

Nicol, M. P., Workman, L., Prins, M., Bateman, L., Ghebrekristos, Y., Mbhele, S., Denkinger, C. M. & Zar, H. J., Oct 2018, In : Pediatric Infectious Disease Journal. 37, 10, p. E261-E263 3 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)