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  • Mark Nicol
2018

Tuberculin skin test conversion and primary progressive tuberculosis disease in the first 5 years of life: a birth cohort study from Cape Town, South Africa

Martinez, L., le Roux, D. M., Barnett, W., Stadler, A., Nicol, M. P. & Zar, H. J., 1 Jan 2018, In : The Lancet Child & Adolescent Health. 2, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Tuberculosis eradication: renewed commitment and global investment required

Cox, H. & Nicol, M. P., 1 Mar 2018, In : The Lancet Infectious Diseases. 18, 3, p. 228-229 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Khonga, M. & Nicol, M. P., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 6-8 3 p.

Research output: Contribution to journalComment/debate

8 Citations (Scopus)

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Dorman, S. E., Schumacher, S. G., Alland, D., Nabeta, P., Armstrong, D. T., King, B., Hall, S. L., Chakravorty, S., Cirillo, D. M., Tukvadze, N., Bablishvili, N., Stevens, W., Scott, L., Rodrigues, C., Kazi, M. I., Joloba, M., Nakiyingi, L., Nicol, M. P., Ghebrekristos, Y., Anyango, I. & 12 others, Murithi, W., Dietze, R., Lyrio Peres, R., Skrahina, A., Auchynka, V., Chopra, K. K., Hanif, M., Liu, X., Yuan, X., Boehme, C. C., Ellner, J. J. & Denkinger, C. M., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Open Access
163 Citations (Scopus)
2019

Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile

Naudé, P. J. W., Claassen-Weitz, S., Gardner-Lubbe, S., Botha, G., Kaba, M., Zar, H. J., Nicol, M. P. & Stein, D. J., 22 Nov 2019, In : Acta Neuropsychiatrica. p. 1-31 31 p.

Research output: Contribution to journalArticle

Open Access
File
45 Downloads (Pure)

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center

Van Hoving, D. J., Lahri, S., Lategan, H. J., Nicol, M. P., Maartens, G. & Meintjes, G., 1 May 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 1, p. e10-e14

Research output: Contribution to journalArticle

2 Citations (Scopus)

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Schutz, C., Barr, D., Andrade, B. B., Shey, M., Ward, A., Janssen, S., Burton, R., Wilkinson, K. A., Sossen, B., Fukutani, K. F., Nicol, M., Maartens, G., Wilkinson, R. J. & Meintjes, G., Jul 2019, In : PLoS Medicine. 16, 7, p. e1002840

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

Kerkhoff, A. D., Sossen, B., Schutz, C., Reipold, E. I., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Nicol, M. P., Meintjes, G., Denkinger, C. M. & Broger, T., 7 Nov 2019, In : The European Respiratory Journal.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis

Di Tanna, G. L., Raza Khaki, A., Theron, G., McCarthy, K., Cox, H., Mupfumi, L., Trajman, A., Sodai Zijenah, L., Mason, P., Bandason, T., Durovni, B., Bara, W., Hoelscher, M., Clowes, P., Mangu, C., Chanda, D., Pym, A., Mwaba, P., Cobelens, F., Nicol, M. P. & 4 others, Dheda, K., Churchyard, G., Fielding, K. & Metcalfe, J. Z., 1 Feb 2019, In : The Lancet Global Health. 7, 2, p. e191-e199

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
1 Citation (Scopus)

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

Schutz, C., Ward, A., Burton, R., Nicol, M. P., Blumenthal, U., Meintjes, G. & Kerkhoff, A. D., 28 Aug 2019, In : Southern African Journal of HIV Medicine. 20, 1, 10 p., 978.

Research output: Contribution to journalArticle

Open Access

Global patterns in monthly activity of influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus: a systematic analysis

RSV Global Epidemiology Network & RESCEU Investigators, Aug 2019, In : The Lancet Global Health. 7, 8, p. E1031-E1045 15 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Guidance for Studies Evaluating the Accuracy of Sputum-Based Tests to Diagnose Tuberculosis

Schumacher, S. G., Wells, W. A., Nicol, M. P., Steingart, K. R., Theron, G., Dorman, S. E., Pai, M., Churchyard, G., Scott, L., Stevens, W., Nabeta, P., Alland, D., Weyer, K., Denkinger, C. M. & Gilpin, C., 8 Oct 2019, In : The Journal of infectious diseases. 220, S3, p. S99-S107

Research output: Contribution to journalArticle

1 Citation (Scopus)

Improving the design of studies evaluating the impact of diagnostic tests for tuberculosis on health outcomes: a qualitative study of perspectives of diverse stakeholders

Ochodo, E. A., Naidoo, S., Schumacher, S., Steingart, K., Deeks, J., Cobelens, F., Bossuyt, P. M., Young, T. & Nicol, M. P., 21 Nov 2019, In : Wellcome Open Research. 4, p. 183

Research output: Contribution to journalArticle

Open Access

Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study

Vanker, A., Nduru, P. M., Barnett, W., Dube, F. S., Sly, P. D., Gie, R. P., Nicol, M. P. & Zar, H. J., Feb 2019, In : ERJ Open Research. 5, 1, 2 p.

Research output: Contribution to journalArticle

Open Access

Influence of Socio-Economic and Psychosocial Profiles on the Human Breast Milk Bacteriome of South African Women

Ojo-Okunola, A., Claassen-Weitz, S., Mwaikono, K. S., Gardner-Lubbe, S., Stein, D. J., Zar, H. J., Nicol, M. P. & du Toit, E., 20 Jun 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Integrating environmental health and genomics research in Africa: challenges and opportunities identified during a Human Heredity and Health in Africa (H3Africa) Consortium workshop

Joubert, B. R., Berhane, K., Chevrier, J., Collman, G., Eskenazi, B., Fobil, J., Hoyo, C., John, C. C., Kumie, A., Nicol, M., Ramsay, M., Smith, J., Steyn, A., Tshala-Katumbay, D. & McAllister, K., Aug 2019, In : Gates Open Research. 2, p. 159

Research output: Contribution to journalArticle

Open Access

Longitudinal Population Dynamics of Staphylococcus aureus in the Nasopharynx During the First Year of Life

Abdulgader, S. M., Robberts, L., Ramjith, J., Nduru, P. M., Dube, F., Gardner-Lubbe, S., Zar, H. J. & Nicol, M. P., 15 Mar 2019, In : Frontiers in Genetics. 10, 10 p., 198.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Microbiological diagnosis of pulmonary tuberculosis in children by oral swab polymerase chain reaction

Nicol, M. P., Wood, R. C., Workman, L., Prins, M., Whitman, C., Ghebrekristos, Y., Mbhele, S., Olson, A., Jones-Engel, L. E., Zar, H. J. & Cangelosi, G. A., 25 Jul 2019, In : Scientific Reports. 9, 1, p. 10789

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Multicenter Study of the Accuracy of the BD MAX™ MDR-TB Assay for Detection of Mycobacterium tuberculosis Complex and Mutations Associated with Resistance to Rifampin and Isoniazid

Shah, M., Paradis, S., Betz, J., Beylis, N., Bharadwaj, R., Caceres, T., Gotuzzo, E., Joloba, M., Mave, V., Nakiyingi, L., Nicol, M. P., Pradhan, N., King, B., Armstrong, D., Knecht, D., Maus, C. E., Cooper, C. K., Dorman, S. E. & Manabe, Y. C., 27 Sep 2019, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalArticle

Nasopharyngeal carriage of antimicrobial-resistant pneumococci in an intensively sampled South African birth cohort

Manenzhe, R., Moodley, C., Abdulgader, S. M., Robberts, F. J. L., Zar, H. J., Nicol, M. P. & Dube, F. S., 27 Mar 2019, In : Frontiers in Microbiology. 10, 10 p., 610.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study

Broger, T., Sossen, B., du Toit, E., Kerkhoff, A. D., Schutz, C., Ivanova Reipold, E., Ward, A., Barr, D. A., Macé, A., Trollip, A., Burton, R., Ongarello, S., Pinter, A., Lowary, T. L., Boehme, C., Nicol, M. P., Meintjes, G. & Denkinger, C. M., 30 May 2019, In : The Lancet Infectious Diseases. 10 p.

Research output: Contribution to journalArticle

Open Access
32 Citations (Scopus)

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa

Kalule, J. B., Smith, A. M., Vulindhlu, M., Tau, N. P., Nicol, M. P., Keddy, K. H. & Robberts, L., 6 Nov 2019, In : BMC Microbiology. 19, 1, 244.

Research output: Contribution to journalArticle

Open Access

Recent developments in the diagnosis of drug-resistant tuberculosis

Nicol, M. P. & Cox, H., 1 Jan 2019, In : Microbiology Australia. 40, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra

Zar, H. J. & Nicol, M. P., 1 Nov 2019, In : Pediatrics. 144, 5

Research output: Contribution to journalArticle

1 Citation (Scopus)

Tuberculosis Diagnosis in Children Using Xpert Ultra on Different Respiratory Specimens

Zar, H. J., Workman, L. J., Prins, M., Bateman, L. J., Mbhele, S. P., Whitman, C. B., Denkinger, C. M. & Nicol, M. P., 15 Dec 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 12, p. 1531-1538

Research output: Contribution to journalArticle

11 Citations (Scopus)

Variation in the observed effect of Xpert MTB/RIF testing for tuberculosis on mortality: A systematic review and analysis of trial design considerations

Ochodo, E. A., Kalema, N., Schumacher, S., Steingart, K., Young, T., Mallett, S., Deeks, J., Cobelens, F., Bossuyt, P. M., Nicol, M. P. & Cattamanchi, A., 2019, In : Wellcome Open Research. 4, p. 173

Research output: Contribution to journalReview article

Open Access

What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations?

Hanifa, Y., Toro Silva, S., Karstaedt, A., Sahid, F., Charalambous, S., Chihota, V. N., Churchyard, G. J., von Gottberg, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Stevens, W., Fielding, K. L. & Grant, A. D., 1 Feb 2019, In : International Journal of Tuberculosis & Lung Disease. 23, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2020

Accuracy of a novel urine test, Fujifilm SILVAMP TB LAM, for the diagnosis of pulmonary tuberculosis in children

Nicol, M. P., Schumacher, S. G., Workman, L., Broger, T., Baard, C., Prins, M., Bateman, L., du Toit, E., van Heerden, J., Szekely, R., Zar, H. J. & Denkinger, C. M., 6 Aug 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalArticle

Advances in the diagnosis of pulmonary tuberculosis in children

Nicol, M. P. & Zar, H. J., 25 May 2020, In : Paediatric Respiratory Reviews.

Research output: Contribution to journalReview article

"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa

Furin, J., Loveday, M., Hlangu, S., Dickson-Hall, L., le Roux, S., Nicol, M. & Cox, H., 17 Jan 2020, In : BMC Public Health. 20, 1, 76.

Research output: Contribution to journalArticle

Open Access

Chronic lung disease in children and adolescents with HIV: a case–control study

the BREATHE Clinical Trial Team, 1 Jan 2020, In : Tropical Medicine and International Health.

Research output: Contribution to journalArticle

Composition of gut microbiota of children and adolescents with perinatal HIV infection taking antiretroviral therapy in Zimbabwe

Breathe Study Team, 14 Jan 2020, In : The Journal of infectious diseases. 221, 3, p. 483-492

Research output: Contribution to journalArticle

Open Access
File
2 Downloads (Pure)

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 2 Mar 2020, In : BMC Infectious Diseases. 20, 1, p. 187

Research output: Contribution to journalLetter

Open Access

Diagnosis of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 2)

Zar, H. J., Moore, D. P., Itzikowitz, G., Green, R. J., Argent, A. C., Avenant, T., Cohen, C., Jeena, P., Masekela, R., Pillay, A., Reubenson, G., Madhi, S. A., Andronikou, S. & Nicol, M. P., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 588-593 6 p.

Research output: Contribution to journalArticle

Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data

Broger, T., Nicol, M. P., Székely, R., Bjerrum, S., Sossen, B., Schutz, C., Opintan, J. A., Johansen, I. S., Mitarai, S., Chikamatsu, K., Kerkhoff, A. D., Macé, A., Ongarello, S., Meintjes, G., Denkinger, C. M. & Schumacher, S. G., May 2020, In : PLoS Medicine. 17, 5, p. e1003113

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 13 Jan 2020, In : BMC Infectious Diseases. 20, 1, p. 33

Research output: Contribution to journalArticle

Open Access

Diagnostic accuracy of three urine lipoarabinomannan tuberculosis assays in HIV-negative outpatients

Broger, T., Nicol, M., Sigal, G., Gotuzzo, E., Zimmer, A. J., Surtie, S., Caceres-Nakiche, T., Mantsoki, A., Reipold, E. I., Székely, R., Tsionsky, M., van Heerden, J., Plisova, T., Chikamatsu, K., Lowary, T. L., Pinter, A., Mitarai, S., Moreau, E., Schumacher, S. G. & Denkinger, C. M., 21 Jul 2020, In : The Journal of clinical investigation.

Research output: Contribution to journalArticle

Diagnostic limitations of clinical case definitions of pertussis in infants and children with severe lower respiratory tract infection

Muloiwa, R., Nicol, M. P., Hussey, G. D. & Zar, H. J., 17 Jul 2020, In : PLoS One. 15, 7, p. e0235703

Research output: Contribution to journalArticle

Open Access

Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region

Tomasicchio, M., Limberis, J., van der Merwe, R., Jacobson, R., Meldau, R., Theron, G., Nicol, M., Warren, R. & Dheda, K., 1 Jul 2020, In : International Journal of Infectious Diseases. 96, p. 240-243

Research output: Contribution to journalArticle

Open Access

Drug-resistant tuberculosis patient care journeys in South Africa: a pilot study using routine laboratory data

Hill, J., Dickson-Hall, L., Grant, A. D., Grundy, C., Black, J., Kielmann, K., Mlisana, K., Mitrani, L., Loveday, M., Moshabela, M., Le Roux, S., Jassat, W., Nicol, M. & Cox, H., 1 Jan 2020, In : International Journal of Tuberculosis & Lung Disease. 24, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Open Access

Epidemiology and aetiology of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 1)

Moore, D. P., Green, R. J., Cohen, C., Itzikowitz, G., Andronikou, S., Argent, A. C., Avenant, T., Jeena, P., Masekela, R., Nicol, M. P., Pillay, A., Reubenson, G., Madhi, S. A. & Zar, H. J., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 583-587 5 p.

Research output: Contribution to journalArticle

Open Access

First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis

Nabeta, P., Seshadri, P., Havumaki, J., Mbhele, S., Hendricks, L., Perkins, M. D., Nicol, M. P. & Denkinger, C. M., 19 Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 115026.

Research output: Contribution to journalArticle

Open Access

Key advances and remaining challenges in childhood and adolescent tuberculosis

Marais, B. J., Nicol, M. & Zar, H. J., 2020, In : Paediatric Respiratory Reviews.

Research output: Contribution to journalEditorial

Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing

Manenzhe, R. I., Dube, F. S., Wright, M., Lennard, K., Zar, H. J., Mounaud, S., Nierman, W. C., Nicol, M. P. & Moodley, C., 2020, In : PLoS One. 15, 4, p. e0231887

Research output: Contribution to journalArticle

Open Access

Management of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 3)

Reubenson, G., Avenant, T., Moore, D. P., Itzikowitz, G., Andronikou, S., Cohen, C., Green, R. J., Jeena, P., Masekela, R., Nicol, M. P., Pillay, A., Madhi, S. A., Zar, H. J. & Argent, A. C., Aug 2020, In : South African Medical Journal. 110, 8, p. 734-740 7 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Optimizing 16S rRNA gene profile analysis from low biomass nasopharyngeal and induced sputum specimens

Claassen-Weitz, S., Gardner-Lubbe, S., Mwaikono, K. S., du Toit, E., Zar, H. J. & Nicol, M. P., 12 May 2020, In : BMC Microbiology. 20, 1, 26 p., 113.

Research output: Contribution to journalArticle

Open Access

Prevention of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 4)

Zar, H. J., Moore, D. P., Andronikou, S., Argent, A. C., Avenant, T., Cohen, C., Green, R. J., Itzikowitz, G., Jeena, P., Nicol, M. P., Pillay, A., Reubenson, G., Masekela, R. & Madhi, S. A., Aug 2020, In : South African Medical Journal. 110, 8, p. 741-746 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)