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  • Mark Nicol
2020

"A very humiliating illness": a qualitative study of patient-centered Care for Rifampicin-Resistant Tuberculosis in South Africa

Furin, J., Loveday, M., Hlangu, S., Dickson-Hall, L., le Roux, S., Nicol, M. & Cox, H., 17 Jan 2020, In : BMC Public Health. 20, 1, 76.

Research output: Contribution to journalArticle

Open Access
2019

Clinical, microbiologic, and immunologic determinants of mortality in hospitalized patients with HIV-associated tuberculosis: A prospective cohort study

Schutz, C., Barr, D., Andrade, B. B., Shey, M., Ward, A., Janssen, S., Burton, R., Wilkinson, K. A., Sossen, B., Fukutani, K. F., Nicol, M., Maartens, G., Wilkinson, R. J. & Meintjes, G., Jul 2019, In : PLoS Medicine. 16, 7, p. e1002840

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2016

Tuberculosis diagnostics: State of the art and future directions

Pai, M., Nicol, M. P. & Boehme, C. C., 1 Jan 2016, In : Microbiology Spectrum. 4, 5, TBTB2-0019-2016.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)
2017

Optimizing Tuberculosis Diagnosis in Human Immunodeficiency Virus-Infected Inpatients Meeting the Criteria of Seriously Ill in the World Health Organization Algorithm

Griesel, R., Stewart, A., van der Plas, H., Sikhondze, W., Rangaka, M. X., Nicol, M. P., Kengne, A. P., Mendelson, M. & Maartens, G., 6 Nov 2017, In : Clinical Infectious Diseases. 66, 9, p. 1419-1426 8 p.

Research output: Contribution to journalArticle

2018

Blood and virus detection on barber clippers

Spengane, Z., Korsman, S., Mkentane, K., Davids, L. M., Zemanay, W., Africa, M., Mbhele, S., Nicol, M., Gumedze, F., Ngwanya, D. & Khumalo, N. P., 1 Apr 2018, In : South African Medical Journal. 108, 4, p. 278-282 5 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2020

Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing

Manenzhe, R. I., Dube, F. S., Wright, M., Lennard, K., Zar, H. J., Mounaud, S., Nierman, W. C., Nicol, M. P. & Moodley, C., 2020, In : PLoS One. 15, 4, p. e0231887

Research output: Contribution to journalArticle

Open Access
2016

Human brucellosis in South Africa: Public health and diagnostic pitfalls

Wojno, J. M., Moodley, C., Pienaar, J., Beylis, N., Jacobsz, L., Nicol, M. P., Rossouw, J. & Bamford, C., 1 Jan 2016, In : South African Medical Journal. 106, 9, p. 883-885 3 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2019

Brief Report: Real-World Performance and Interobserver Agreement of Urine Lipoarabinomannan in Diagnosing HIV-Associated Tuberculosis in an Emergency Center

Van Hoving, D. J., Lahri, S., Lategan, H. J., Nicol, M. P., Maartens, G. & Meintjes, G., 1 May 2019, In : Journal of acquired immune deficiency syndromes (1999). 81, 1, p. e10-e14

Research output: Contribution to journalArticle

Indoor air pollution and tobacco smoke exposure: impact on nasopharyngeal bacterial carriage in mothers and infants in an African birth cohort study

Vanker, A., Nduru, P. M., Barnett, W., Dube, F. S., Sly, P. D., Gie, R. P., Nicol, M. P. & Zar, H. J., Feb 2019, In : ERJ Open Research. 5, 1

Research output: Contribution to journalArticle

Open Access
2017

Improved method for collection of sputum for tuberculosis testing to ensure adequate sample volumes for molecular diagnostic testing

Fisher, M., Dolby, T., Surtie, S., Omar, G., Hapeela, N., Basu, D., DeWalt, A., Kelso, D., Nicol, M. & McFall, S., 1 Apr 2017, In : Journal of Microbiological Methods. 135, p. 35-40 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2020

Correction to: Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 2 Mar 2020, In : BMC Infectious Diseases. 20, 1, p. 187

Research output: Contribution to journalLetter

Open Access
2016

Incidence and diagnosis of pertussis in South African children hospitalized with lower respiratory tract infection

Muloiwa, R., Dube, F. S., Nicol, M. P., Zar, H. J. & Hussey, G. D., 10 Mar 2016, In : Pediatric Infectious Disease Journal. 35, 6, p. 611-616 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2018

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

Nicol, M. P., Workman, L., Prins, M., Bateman, L., Ghebrekristos, Y., Mbhele, S., Denkinger, C. M. & Zar, H. J., Oct 2018, In : Pediatric Infectious Disease Journal. 37, 10, p. E261-E263 3 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2020

First clinical assessment of a prototype assay to detect the enzymatic activity of β-lactamase as a marker for pulmonary tuberculosis

Nabeta, P., Seshadri, P., Havumaki, J., Mbhele, S., Hendricks, L., Perkins, M. D., Nicol, M. P. & Denkinger, C. M., 19 Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 115026.

Research output: Contribution to journalArticle

Open Access
2016

Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: A nested case-control study of the Drakenstein Child Health Study

Zar, H. J., Barnett, W., Stadler, A., Gardner-Lubbe, S., Myer, L. & Nicol, M. P., 1 Jun 2016, In : The Lancet Respiratory Medicine. 4, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

Open Access
62 Citations (Scopus)
2017

Utility of second-generation line probe assay (Hain MTBDRplus) directly on 2-month sputum specimens for monitoring tuberculosis treatment response

Rockwood, N., Wojno, J., Ghebrekristos, Y., Nicol, M. P., Meintjes, G. & Wilkinson, R. J., 1 May 2017, In : Journal of Clinical Microbiology. 55, 5, p. 1508-1515 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2018

Serologic Responses in Childhood Pulmonary Tuberculosis

Nonyane, B. A. S., Nicol, M. P., Andreas, N. J., Rimmele, S., Schneiderhan-Marra, N., Workman, L. J., Perkins, M. D., Joos, T., Broger, T., Ellner, J. J., Alland, D., Kampmann, B., Dorman, S. E. & Zar, H. J., 1 Jan 2018, In : Pediatric Infectious Disease Journal. 37, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

How should tuberculosis molecular diagnostics be adapted for use in seriously ill HIV patients?

Nicol, M. P., 1 Dec 2016, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 16, 12, p. 1237-1239 3 p.

Research output: Contribution to journalEditorial

2019

What causes symptoms suggestive of tuberculosis in HIV-positive people with negative initial investigations?

Hanifa, Y., Toro Silva, S., Karstaedt, A., Sahid, F., Charalambous, S., Chihota, V. N., Churchyard, G. J., von Gottberg, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Stevens, W., Fielding, K. L. & Grant, A. D., 1 Feb 2019, In : International Journal of Tuberculosis & Lung Disease. 23, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2020

Chronic lung disease in children and adolescents with HIV: a case–control study

the BREATHE Clinical Trial Team, 1 Jan 2020, In : Tropical Medicine and International Health.

Research output: Contribution to journalArticle

2019

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa

Kalule, J. B., Smith, A. M., Vulindhlu, M., Tau, N. P., Nicol, M. P., Keddy, K. H. & Robberts, L., 6 Nov 2019, In : BMC Microbiology. 19, 1, 244.

Research output: Contribution to journalArticle

Open Access
2018

Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Khonga, M. & Nicol, M. P., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 6-8 3 p.

Research output: Contribution to journalComment/debate

6 Citations (Scopus)
2019

Novel lipoarabinomannan point-of-care tuberculosis test for people with HIV: a diagnostic accuracy study

Broger, T., Sossen, B., du Toit, E., Kerkhoff, A. D., Schutz, C., Ivanova Reipold, E., Ward, A., Barr, D. A., Macé, A., Trollip, A., Burton, R., Ongarello, S., Pinter, A., Lowary, T. L., Boehme, C., Nicol, M. P., Meintjes, G. & Denkinger, C. M., 30 May 2019, In : The Lancet Infectious Diseases. 10 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)
2018

Tuberculin skin test conversion and primary progressive tuberculosis disease in the first 5 years of life: a birth cohort study from Cape Town, South Africa

Martinez, L., le Roux, D. M., Barnett, W., Stadler, A., Nicol, M. P. & Zar, H. J., 1 Jan 2018, In : The Lancet Child & Adolescent Health. 2, 1, p. 46-55 10 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
2019

Integrating environmental health and genomics research in Africa: challenges and opportunities identified during a Human Heredity and Health in Africa (H3Africa) Consortium workshop

Joubert, B. R., Berhane, K., Chevrier, J., Collman, G., Eskenazi, B., Fobil, J., Hoyo, C., John, C. C., Kumie, A., Nicol, M., Ramsay, M., Smith, J., Steyn, A., Tshala-Katumbay, D. & McAllister, K., Aug 2019, In : Gates Open Research. 2, p. 159

Research output: Contribution to journalArticle

Open Access
2017
Open Access
4 Citations (Scopus)
2018

Human breast milk bacteriome in health and disease

Ojo-Okunola, A., Nicol, M. & du Toit, E., 3 Nov 2018, In : Nutrients. 10, 11, 1643.

Research output: Contribution to journalReview article

Open Access
10 Citations (Scopus)
2019

Microbiological diagnosis of pulmonary tuberculosis in children by oral swab polymerase chain reaction

Nicol, M. P., Wood, R. C., Workman, L., Prins, M., Whitman, C., Ghebrekristos, Y., Mbhele, S., Olson, A., Jones-Engel, L. E., Zar, H. J. & Cangelosi, G. A., 25 Jul 2019, In : Scientific Reports. 9, 1, p. 10789

Research output: Contribution to journalArticle

Open Access
2020

Diagnostic accuracy of a novel tuberculosis point-of-care urine lipoarabinomannan assay for people living with HIV: A meta-analysis of individual in- and outpatient data

Broger, T., Nicol, M. P., Székely, R., Bjerrum, S., Sossen, B., Schutz, C., Opintan, J. A., Johansen, I. S., Mitarai, S., Chikamatsu, K., Kerkhoff, A. D., Macé, A., Ongarello, S., Meintjes, G., Denkinger, C. M. & Schumacher, S. G., May 2020, In : PLoS Medicine. 17, 5, p. e1003113

Research output: Contribution to journalArticle

Open Access
2017

Remembering the basics: interventions to improve sputum collection for tuberculosis diagnosis

Centner, C. M. & Nicol, M. P., 1 Aug 2017, In : The Lancet Global Health. 5, 8, p. e728-e729

Research output: Contribution to journalComment/debate

2019

Association of maternal prenatal psychological stressors and distress with maternal and early infant faecal bacterial profile

Naudé, P. J. W., Claassen-Weitz, S., Gardner-Lubbe, S., Botha, G., Kaba, M., Zar, H. J., Nicol, M. P. & Stein, D. J., 22 Nov 2019, In : Acta Neuropsychiatrica. p. 1-31 31 p.

Research output: Contribution to journalArticle

Open Access
File
33 Downloads (Pure)
2017

Advances in the diagnosis of pneumonia in children

Zar, H. J., Andronikou, S. & Nicol, M. P., 26 Jul 2017, In : BMJ (Online). 358, j2739.

Research output: Contribution to journalReview article

18 Citations (Scopus)
2016

Distinct patterns in human milk microbiota and fatty acid profiles across specific geographic locations

Kumar, H., du Toit, E., Kulkarni, A., Aakko, J., Linderborg, K. M., Zhang, Y., Nicol, M. P., Isolauri, E., Yang, B., Collado, M. C. & Salminen, S., 13 Oct 2016, In : Frontiers in Microbiology. 7, OCT, 1619.

Research output: Contribution to journalArticle

Open Access
71 Citations (Scopus)
2017

Carriage of extended-spectrum beta-lactamase-producing enterobacteriaceae in HIV-infected children in Zimbabwe

Wilmore, S. M. S., Kranzer, K., Williams, A., Makamure, B., Nhidza, A. F., Mayini, J., Bandason, T., Metcalfe, J., Nicol, M. P., Balakrishnan, I., Ellington, M. J., Woodford, N., Hopkins, S., McHugh, T. D. & Ferrand, R. A., 1 May 2017, In : Journal of Medical Microbiology. 66, 5, p. 609-615 7 p., 000474.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2017

Diagnostic accuracy of two multiplex real-Time polymerase chain reaction assays for the diagnosis of meningitis in children in a resource-limited setting

Khumalo, J., Nicol, M., Hardie, D., Muloiwa, R., Mteshana, P. & Bamford, C., 1 Mar 2017, In : PLoS One. 12, 3, e0173948.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Impact of point-of-care xpert MTB/RIF on tuberculosis treatment initiation: A cluster-randomized trial

Lessells, R. J., Cooke, G. S., McGrath, N., Nicol, M. P., Newell, M. L. & Godfrey-Faussett, P., 1 Oct 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 7, p. 901-910 10 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2016

Diagnostic accuracy of lateral flow urine LAM assay for TB screening of adults with advanced immunosuppression attending routine HIV care in South Africa

Hanifa, Y., Fielding, K. L., Chihota, V. N., Adonis, L., Charalambous, S., Karstaedt, A., McCarthy, K., Nicol, M. P., Ndlovu, N. T., Sahid, F., Churchyard, G. J. & Grant, A. D., 1 Jun 2016, In : PLoS One. 11, 6, e0156866.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2020

Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 13 Jan 2020, In : BMC Infectious Diseases. 20, 1, p. 33

Research output: Contribution to journalArticle

Open Access
2018

Development of a clinical prediction rule to diagnose Pneumocystis jirovecii pneumonia in the World Health Organization's algorithm for seriously ill HIV-infected patients

Maartens, G., Stewart, A., Griesel, R., Kengne, A. P., Dube, F., Nicol, M., Rangaka, M. X. & Mendelson, M., 2018, In : Southern African Journal of HIV Medicine. 19, 1, p. 851

Research output: Contribution to journalArticle

Open Access
2017

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study

Shi, T., McAllister, D. A., O'Brien, K. L., Simoes, E. A. F., Madhi, S. A., Gessner, B. D., Polack, F. P., Balsells, E., Acacio, S., Aguayo, C., Alassani, I., Ali, A., Antonio, M., Awasthi, S., Awori, J. O., Azziz-Baumgartner, E., Baggett, H. C., Baillie, V. L., Balmaseda, A., Barahona, A. & 102 others, Basnet, S., Bassat, Q., Basualdo, W., Bigogo, G., Bont, L., Breiman, R. F., Brooks, W. A., Broor, S., Bruce, N., Bruden, D., Buchy, P., Campbell, S., Carosone-Link, P., Chadha, M., Chipeta, J., Chou, M., Clara, W., Cohen, C., de Cuellar, E., Dang, D. A., Dash-yandag, B., Deloria-Knoll, M., Dherani, M., Eap, T., Ebruke, B. E., Echavarria, M., de Freitas Lázaro Emediato, C. C., Fasce, R. A., Feikin, D. R., Feng, L., Gentile, A., Gordon, A., Goswami, D., Goyet, S., Groome, M., Halasa, N., Hirve, S., Homaira, N., Howie, S. R. C., Jara, J., Jroundi, I., Kartasasmita, C. B., Khuri-Bulos, N., Kotloff, K. L., Krishnan, A., Libster, R., Lopez, O., Lucero, M. G., Lucion, F., Lupisan, S. P., Marcone, D. N., McCracken, J. P., Mejia, M., Moisi, J. C., Montgomery, J. M., Moore, D. P., Moraleda, C., Moyes, J., Munywoki, P., Mutyara, K., Nicol, M. P., Nokes, D. J., Nymadawa, P., da Costa Oliveira, M. T., Oshitani, H., Pandey, N., Paranhos-Baccalà, G., Phillips, L. N., Picot, V. S., Rahman, M., Rakoto-Andrianarivelo, M., Rasmussen, Z. A., Rath, B. A., Robinson, A., Romero, C., Russomando, G., Salimi, V., Sawatwong, P., Scheltema, N., Schweiger, B., Scott, J. A. G., Seidenberg, P., Shen, K., Singleton, R., Sotomayor, V., Strand, T. A., Sutanto, A., Sylla, M., Tapia, M. D., Thamthitiwat, S., Thomas, E. D., Tokarz, R., Turner, C., Venter, M., Waicharoen, S., Wang, J., Watthanaworawit, W., Yoshida, L. M., Yu, H., Zar, H. J., Campbell, H. & Nair, H., 2 Sep 2017, In : The Lancet. 390, 10098, p. 946-958 13 p.

Research output: Contribution to journalArticle

Open Access
404 Citations (Scopus)