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  • Mark Nicol
2017

Carriage of extended-spectrum beta-lactamase-producing enterobacteriaceae in HIV-infected children in Zimbabwe

Wilmore, S. M. S., Kranzer, K., Williams, A., Makamure, B., Nhidza, A. F., Mayini, J., Bandason, T., Metcalfe, J., Nicol, M. P., Balakrishnan, I., Ellington, M. J., Woodford, N., Hopkins, S., McHugh, T. D. & Ferrand, R. A., 1 May 2017, In : Journal of Medical Microbiology. 66, 5, p. 609-615 7 p., 000474.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2016

Highly sensitive sequence specific qPCR detection of Mycobacterium tuberculosis complex in respiratory specimens

Reed, J. L., Walker, Z. J., Basu, D., Allen, V., Nicol, M. P., Kelso, D. M. & McFall, S. M., 1 Dec 2016, In : Tuberculosis. 101, p. 114-124 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
2018

Characterisation of STEC and other diarrheic E. coli isolated on CHROMagar™STEC at a tertiary referral hospital, Cape Town

Kalule, J. B., Keddy, K. H. & Nicol, M. P., 8 Jun 2018, In : BMC Microbiology. 18, 1, 55.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2017

Diagnostic accuracy of two multiplex real-Time polymerase chain reaction assays for the diagnosis of meningitis in children in a resource-limited setting

Khumalo, J., Nicol, M., Hardie, D., Muloiwa, R., Mteshana, P. & Bamford, C., 1 Mar 2017, In : PLoS One. 12, 3, e0173948.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
2016

Incidence and diagnosis of pertussis in South African children hospitalized with lower respiratory tract infection

Muloiwa, R., Dube, F. S., Nicol, M. P., Zar, H. J. & Hussey, G. D., 10 Mar 2016, In : Pediatric Infectious Disease Journal. 35, 6, p. 611-616 6 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2019

Longitudinal Population Dynamics of Staphylococcus aureus in the Nasopharynx During the First Year of Life

Abdulgader, S. M., Robberts, L., Ramjith, J., Nduru, P. M., Dube, F., Gardner-Lubbe, S., Zar, H. J. & Nicol, M. P., 15 Mar 2019, In : Frontiers in Genetics. 10, 10 p., 198.

Research output: Contribution to journalArticle

Open Access

Nasopharyngeal carriage of antimicrobial-resistant pneumococci in an intensively sampled South African birth cohort

Manenzhe, R., Moodley, C., Abdulgader, S. M., Robberts, F. J. L., Zar, H. J., Nicol, M. P. & Dube, F. S., 27 Mar 2019, In : Frontiers in Microbiology. 10, 10 p., 610.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2020

'SILVAMP TB LAM' rapid urine tuberculosis test predicts mortality in hospitalized HIV patients in South Africa

Sossen, B., Broger, T., Kerkhoff, A. D., Schutz, C., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Wilkinson, R. J., Barr, D. A., Nicol, M. P., Denkinger, C. M. & Meintjes, G., 9 Jan 2020, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Research output: Contribution to journalReview article

Open Access

Diagnostic limitations of clinical case definitions of pertussis in infants and children with severe lower respiratory tract infection

Muloiwa, R., Nicol, M. P., Hussey, G. D. & Zar, H. J., 17 Jul 2020, In : PLoS One. 15, 7, p. e0235703

Research output: Contribution to journalArticle

Open Access
2018

Xpert MTB/RIF Ultra: a gamechanger for tuberculous meningitis?

Khonga, M. & Nicol, M. P., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 6-8 3 p.

Research output: Contribution to journalComment/debate

8 Citations (Scopus)
2016

Aetiology of childhood pneumonia in a well vaccinated South African birth cohort: A nested case-control study of the Drakenstein Child Health Study

Zar, H. J., Barnett, W., Stadler, A., Gardner-Lubbe, S., Myer, L. & Nicol, M. P., 1 Jun 2016, In : The Lancet Respiratory Medicine. 4, 6, p. 463-472 10 p.

Research output: Contribution to journalArticle

Open Access
63 Citations (Scopus)

Analytical and clinical evaluation of the epistem genedrive assay for detection of mycobacterium tuberculosis

Shenai, S., Armstrong, D. T., Valli, E., Dolinger, D. L., Nakiyingi, L., Dietze, R., Dalcolmo, M. P., Nicol, M. P., Zemanay, W., Manabe, Y., Hadad, D. J., Marques-Rodrigues, P., Palaci, M., Peres, R. L., Gaeddert, M., Armakovitch, S., Nonyane, B. A. S., Denkinger, C. M., Banada, P., Joloba, M. L. & 4 others, Ellner, J., Boehme, C., Alland, D. & Dorman, S. E., 1 Apr 2016, In : Journal of Clinical Microbiology. 54, 4, p. 1051-1057 7 p.

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)
2017

Utility of second-generation line probe assay (Hain MTBDRplus) directly on 2-month sputum specimens for monitoring tuberculosis treatment response

Rockwood, N., Wojno, J., Ghebrekristos, Y., Nicol, M. P., Meintjes, G. & Wilkinson, R. J., 1 May 2017, In : Journal of Clinical Microbiology. 55, 5, p. 1508-1515 8 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)
2018

Accuracy of Xpert Mtb/Rif Ultra for the Diagnosis of Pulmonary Tuberculosis in Children

Nicol, M. P., Workman, L., Prins, M., Bateman, L., Ghebrekristos, Y., Mbhele, S., Denkinger, C. M. & Zar, H. J., Oct 2018, In : Pediatric Infectious Disease Journal. 37, 10, p. E261-E263 3 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2016

Current knowledge and future research directions on fecal bacterial patterns and their association with asthma

Claassen-Weitz, S., Wiysonge, C. S., Machingaidze, S., Thabane, L., Horsnell, W. G. C., Zar, H. J., Nicol, M. P. & Kaba, M., 1 Jan 2016, In : Frontiers in Microbiology. 7, JUN, 838.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa

Dube, F. S., Kaba, M., Robberts, F. J. L., Tow, L. A., Lubbe, S., Zar, H. J. & Nicol, M. P., 24 Oct 2016, In : BMC Infectious Diseases. 16, 1, 12 p., 597.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
2019

Guidance for Studies Evaluating the Accuracy of Sputum-Based Tests to Diagnose Tuberculosis

Schumacher, S. G., Wells, W. A., Nicol, M. P., Steingart, K. R., Theron, G., Dorman, S. E., Pai, M., Churchyard, G., Scott, L., Stevens, W., Nabeta, P., Alland, D., Weyer, K., Denkinger, C. M. & Gilpin, C., 8 Oct 2019, In : The Journal of infectious diseases. 220, S3, p. S99-S107

Research output: Contribution to journalArticle

2017

Development of a real-time PCR assay and comparison to CHROMagar (TM) STEC to screen for Shiga toxin-producing Escherichia coli in stool, Cape Town, South Africa

Kalule, J. B., Keddy, K. H., Smith, A., Nicol, M. P. & Robberts, L., 14 Dec 2017, In : African journal of laboratory medicine. 6, 1, 8 p., 609.

Research output: Contribution to journalArticle

Open Access
2019
9 Citations (Scopus)

Influence of Socio-Economic and Psychosocial Profiles on the Human Breast Milk Bacteriome of South African Women

Ojo-Okunola, A., Claassen-Weitz, S., Mwaikono, K. S., Gardner-Lubbe, S., Stein, D. J., Zar, H. J., Nicol, M. P. & du Toit, E., 20 Jun 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Prevalence and antibiotic susceptibility patterns of enteric bacterial pathogens in human and non-human sources in an urban informal settlement in Cape Town, South Africa

Kalule, J. B., Smith, A. M., Vulindhlu, M., Tau, N. P., Nicol, M. P., Keddy, K. H. & Robberts, L., 6 Nov 2019, In : BMC Microbiology. 19, 1, 244.

Research output: Contribution to journalArticle

Open Access
2020

The Determinants of the Human Milk Metabolome and Its Role in Infant Health

Ojo-Okunola, A., Cacciatore, S., Nicol, M. P. & du Toit, E., 20 Feb 2020, In : Metabolites. 10, 2

Research output: Contribution to journalReview article

Open Access
2018

Xpert MTB/RIF Ultra for detection of Mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study

Dorman, S. E., Schumacher, S. G., Alland, D., Nabeta, P., Armstrong, D. T., King, B., Hall, S. L., Chakravorty, S., Cirillo, D. M., Tukvadze, N., Bablishvili, N., Stevens, W., Scott, L., Rodrigues, C., Kazi, M. I., Joloba, M., Nakiyingi, L., Nicol, M. P., Ghebrekristos, Y., Anyango, I. & 12 others, Murithi, W., Dietze, R., Lyrio Peres, R., Skrahina, A., Auchynka, V., Chopra, K. K., Hanif, M., Liu, X., Yuan, X., Boehme, C. C., Ellner, J. J. & Denkinger, C. M., 1 Jan 2018, In : The Lancet Infectious Diseases. 18, 1, p. 76-84 9 p.

Research output: Contribution to journalArticle

Open Access
156 Citations (Scopus)
2017

Disseminated tuberculosis among hospitalised HIV patients in South Africa: A common condition that can be rapidly diagnosed using urine-based assays

Kerkhoff, A. D., Barr, D. A., Schutz, C., Burton, R., Nicol, M. P., Lawn, S. D. & Meintjes, G., 1 Dec 2017, In : Scientific Reports. 7, 1, 10931.

Research output: Contribution to journalArticle

Open Access
24 Citations (Scopus)
2016

Diagnostic Test Accuracy in Childhood Pulmonary Tuberculosis: A Bayesian Latent Class Analysis

Schumacher, S. G., Van Smeden, M., Dendukuri, N., Joseph, L., Nicol, M. P., Pai, M. & Zar, H. J., 1 Nov 2016, In : American Journal of Epidemiology. 184, 9, p. 690-700 11 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Tuberculosis diagnostics: State of the art and future directions

Pai, M., Nicol, M. P. & Boehme, C. C., 1 Jan 2016, In : Microbiology Spectrum. 4, 5, TBTB2-0019-2016.

Research output: Contribution to journalArticle

Open Access
28 Citations (Scopus)
2017

Remembering the basics: interventions to improve sputum collection for tuberculosis diagnosis

Centner, C. M. & Nicol, M. P., 1 Aug 2017, In : The Lancet Global Health. 5, 8, p. e728-e729

Research output: Contribution to journalComment/debate

The Influence of HIV on the Evolution of Mycobacterium tuberculosis

Koch, A. S., Brites, D., Stucki, D., Evans, J. C., Seldon, R., Heekes, A., Mulder, N., Nicol, M., Oni, T., Mizrahi, V., Warner, D. F., Parkhill, J., Gagneux, S., Martin, D. P. & Wilkinson, R. J., 1 Jul 2017, In : Molecular Biology and Evolution. 34, 7, p. 1654-1668 15 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Impact of point-of-care xpert MTB/RIF on tuberculosis treatment initiation: A cluster-randomized trial

Lessells, R. J., Cooke, G. S., McGrath, N., Nicol, M. P., Newell, M. L. & Godfrey-Faussett, P., 1 Oct 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 7, p. 901-910 10 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Childhood tuberculosis is associated with decreased abundance of T cell gene transcripts and impaired T cell function

Hemingway, C., Berk, M., Anderson, S. T., Wright, V. J., Hamilton, S., Eleftherohorinou, H., Kaforou, M., Goldgof, G. M., Hickman, K., Kampmann, B., Schoeman, J., Eley, B., Beatty, D., Pienaar, S., Nicol, M. P., Griffiths, M. J., Waddell, S. J., Newton, S. M., Coin, L. J., Relman, D. A. & 2 others, Montana, G. & Levin, M., 1 Nov 2017, In : PLoS One. 12, 11, e0185973.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: Phenotypic and genotypic analysis of isolates

GERMS-SA Surveillance Network & Nicol, M., 29 Sep 2017, In : BMC Infectious Diseases. 17, 1, 9 p., 656.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Improved method for collection of sputum for tuberculosis testing to ensure adequate sample volumes for molecular diagnostic testing

Fisher, M., Dolby, T., Surtie, S., Omar, G., Hapeela, N., Basu, D., DeWalt, A., Kelso, D., Nicol, M. & McFall, S., 1 Apr 2017, In : Journal of Microbiological Methods. 135, p. 35-40 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Delays and loss to follow-up before treatment of drug-resistant tuberculosis following implementation of Xpert MTB/RIF in South Africa: A retrospective cohort study

Cox, H., Dickson-Hall, L., Ndjeka, N., van’t Hoog, A., Grant, A., Cobelens, F., Stevens, W. & Nicol, M., 1 Feb 2017, In : PLoS Medicine. 14, 2, e1002238.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)
2016

How should tuberculosis molecular diagnostics be adapted for use in seriously ill HIV patients?

Nicol, M. P., 1 Dec 2016, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 16, 12, p. 1237-1239 3 p.

Research output: Contribution to journalEditorial

2019

Strengthening Diagnosis of Pulmonary Tuberculosis in Children: The Role of Xpert MTB/RIF Ultra

Zar, H. J. & Nicol, M. P., 1 Nov 2019, In : Pediatrics. 144, 5

Research output: Contribution to journalArticle

1 Citation (Scopus)

Improving the design of studies evaluating the impact of diagnostic tests for tuberculosis on health outcomes: a qualitative study of perspectives of diverse stakeholders

Ochodo, E. A., Naidoo, S., Schumacher, S., Steingart, K., Deeks, J., Cobelens, F., Bossuyt, P. M., Young, T. & Nicol, M. P., 21 Nov 2019, In : Wellcome Open Research. 4, p. 183

Research output: Contribution to journalArticle

Open Access
2020

Longitudinal changes in the nasopharyngeal resistome of South African infants using shotgun metagenomic sequencing

Manenzhe, R. I., Dube, F. S., Wright, M., Lennard, K., Zar, H. J., Mounaud, S., Nierman, W. C., Nicol, M. P. & Moodley, C., 2020, In : PLoS One. 15, 4, p. e0231887

Research output: Contribution to journalArticle

Open Access
2018

Longitudinal characterization of nasopharyngeal colonization with Streptococcus pneumoniae in a South African birth cohort post 13-valent pneumococcal conjugate vaccine implementation

Dube, F. S., Ramjith, J., Gardner-Lubbe, S., Nduru, P., Robberts, F. J. L., Wolter, N., Zar, H. J. & Nicol, M. P., 1 Dec 2018, In : Scientific Reports. 8, 1, 12497.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Gene expression in cord blood links genetic risk for neurodevelopmental disorders with maternal psychological distress and adverse childhood outcomes

Breen, M. S., Wingo, A. P., Koen, N., Donald, K. A., Nicol, M., Zar, H. J., Ressler, K. J., Buxbaum, J. D. & Stein, D. J., 1 Oct 2018, In : Brain, Behavior, and Immunity. 73, p. 320-330 11 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

HIV-exposure, early life feeding practices and delivery mode impacts on faecal bacterial profiles in a South African birth cohort

Claassen-Weitz, S., Gardner-Lubbe, S., Nicol, P., Botha, G., Mounaud, S., Shankar, J., Nierman, W. C., Mulder, N., Budree, S., Zar, H. J., Nicol, M. P. & Kaba, M., 1 Dec 2018, In : Scientific Reports. 8, 1, 5078.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)
2019

Recent developments in the diagnosis of drug-resistant tuberculosis

Nicol, M. P. & Cox, H., 1 Jan 2019, In : Microbiology Australia. 40, 2, p. 82-86 5 p.

Research output: Contribution to journalArticle

False rifampicin resistant results using Xpert MTB/RIF on urine samples in hospitalised HIV-infected patients

Schutz, C., Ward, A., Burton, R., Nicol, M. P., Blumenthal, U., Meintjes, G. & Kerkhoff, A. D., 28 Aug 2019, In : Southern African Journal of HIV Medicine. 20, 1, 10 p., 978.

Research output: Contribution to journalArticle

Open Access
2020

Diagnostic accuracy of the Xpert MTB/Rif Ultra for tuberculosis adenitis

Antel, K., Oosthuizen, J., Malherbe, F., Louw, V. J., Nicol, M. P., Maartens, G. & Verburgh, E., 13 Jan 2020, In : BMC Infectious Diseases. 20, 1, p. 33

Research output: Contribution to journalArticle

Open Access

Diagnosis of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 2)

Zar, H. J., Moore, D. P., Itzikowitz, G., Green, R. J., Argent, A. C., Avenant, T., Cohen, C., Jeena, P., Masekela, R., Pillay, A., Reubenson, G., Madhi, S. A., Andronikou, S. & Nicol, M. P., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 588-593 6 p.

Research output: Contribution to journalArticle

Epidemiology and aetiology of community-acquired pneumonia in children: South African Thoracic Society guidelines (part 1)

Moore, D. P., Green, R. J., Cohen, C., Itzikowitz, G., Andronikou, S., Argent, A. C., Avenant, T., Jeena, P., Masekela, R., Nicol, M. P., Pillay, A., Reubenson, G., Madhi, S. A. & Zar, H. J., Jul 2020, In : SAMJ South African Medical Journal. 110, 7, p. 583-587 5 p.

Research output: Contribution to journalArticle

Open Access
2017

Optimizing Tuberculosis Diagnosis in Human Immunodeficiency Virus-Infected Inpatients Meeting the Criteria of Seriously Ill in the World Health Organization Algorithm

Griesel, R., Stewart, A., van der Plas, H., Sikhondze, W., Rangaka, M. X., Nicol, M. P., Kengne, A. P., Mendelson, M. & Maartens, G., 6 Nov 2017, In : Clinical Infectious Diseases. 66, 9, p. 1419-1426 8 p.

Research output: Contribution to journalArticle

2019

Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

Kerkhoff, A. D., Sossen, B., Schutz, C., Reipold, E. I., Trollip, A., Moreau, E., Schumacher, S. G., Burton, R., Ward, A., Nicol, M. P., Meintjes, G., Denkinger, C. M. & Broger, T., 7 Nov 2019, In : The European Respiratory Journal.

Research output: Contribution to journalEditorial