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• Abstract/Meeting Abstract

  Loss of SLIRP is associated with poorer prognosis and increased invasion in colorectal cancer

  Candy, P. A., Colley, S. M., Phillips, M. R., Redfern, A. D., Wood, B. A. & Leedman, P. J., Jun 2018, In : Clinical Endocrinology. 89, p. 41-41 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• Article

  Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

  Hilton, H. N., Graham, J. D., Oakes, S. R., Silvestri, A., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, p. 8651-8664

  Research output: Contribution to journal › Article

  20 Citations (Scopus)

• ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-alpha

  Jowett, J. B. M., Okada, Y., Leedman, P., Curran, J. E., Johnson, M. P., Moses, E., Goring, H. H. H., Mochizuki, S., Blangero, J., Stone, L., Allen, H., Mitchell, C. & Matthews, V., 25 Sep 2012, In : Immunology and Cell Biology. 90, 10, p. 966-973

  Research output: Contribution to journal › Article

  Open Access

  File

  • human TNF protein
  • Metabolic Syndrome
  • Metalloproteases
  • Tumor Necrosis Factor-alpha
  • Macrophages
  12 Citations (Scopus)

  247 Downloads (Pure)

• Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort

  Bremner, A., Feddema, P., Leedman, P., Brown, S. J., Beilby, J., Lim, E., Wilson, S., O'Leary, P. & Walsh, J., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, 5, p. 1554-1562

  Research output: Contribution to journal › Article

  • Health Surveys
  • Longitudinal Studies
  • Thyroid Gland
  • Aging of materials
  • Bioactivity
  160 Citations (Scopus)

• A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

  Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A., Beilby, J., Leedman, P., Hattersley, A. T., Vaidya, B., Frayling, T., Evans, J., Timpson, N. J., Tobias, J. H., Walsh, J. & Dayan, C. M., 2011, In : European Journal of Endocrinology. 164, p. 773-780

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma

  Kabir, T. D., Ganda, C., Brown, R. M., Beveridge, D. J., Richardson, K. L., Chaturvedi, V., Candy, P., Epis, M., Wintle, L., Kalinowski, F., Kopp, C., Stuart, L. M., Yeoh, G. C., George, J. & Leedman, P. J., 1 Jan 2018, In : Hepatology. 67, 1, p. 216-231 16 p.

  Research output: Contribution to journal › Article

  • Sorafenib
  • MicroRNAs
  • Hepatocellular Carcinoma
  • Growth
  • Proto-Oncogene Proteins c-akt
  56 Citations (Scopus)

• Breast cancer prognosis predicted by nuclear receptor-coregulator networks

  Doan, T. B., Eriksson, N. A., Graham, D., Funder, J. W., Simpson, E. R., Kuczek, E. S., Clyne, C., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., Jul 2014, In : Molecular Oncology. 8, 5, p. 998-1013

  Research output: Contribution to journal › Article

  Open Access

  • Cytoplasmic and Nuclear Receptors
  • Breast Neoplasms
  • Breast
  • Neoplasms
  • Gene Expression
  14 Citations (Scopus)

• Clinical potential of microRNA-7 in cancer.

  Horsham, J., Kalinowski, F., Epis, M., Ganda, C., Brown, R. & Leedman, P., 2015, In : Journal of Clinical Medicine. 4, 9, p. 1668-1687

  Research output: Contribution to journal › Article

  Open Access

• Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides

  Yoga, Y. M. K., Traore, D. A. K., Sidiqi, M., Szeto, C., Pendini, N. R., Barker, A., Leedman, P., Wilce, J. A. & Wilce, M. C. J., 2012, In : Nucleic Acids Research. 40, p. 5101-5114

  Research output: Contribution to journal › Article

  Open Access
  25 Citations (Scopus)

• Direct in vivo comparison of [¹⁸F]PSMA-1007 with [⁶⁸Ga]Ga-PSMA-11 and [¹⁸F]AlF-PSMA-11 in mice bearing PSMA-expressing xenografts

  Ioppolo, J. A., Nezich, R. A., Richardson, K. L., Morandeau, L., Leedman, P. J. & Price, R. I., Jul 2020, In : Applied Radiation and Isotopes. 161, 109164.

  Research output: Contribution to journal › Article

  • mice
  • tumors
  • magnetohydrodynamic stability
  • bones
  • tracers
  2 Citations (Scopus)

• ETS1 induces transforming growth factor β signaling and promotes epithelial-to-mesenchymal transition in prostate cancer cells

  Australian Prostate Cancer BioResource, Jan 2019, In : Journal of Cellular Biochemistry. 120, 1, p. 848-860 13 p.

  Research output: Contribution to journal › Article

  • Epithelial-Mesenchymal Transition
  • Transforming Growth Factors
  • Cells
  • Prostate
  • Tumors
  6 Citations (Scopus)

• Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

  Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

  Research output: Contribution to journal › Article

  Open Access

  • Disintegrins
  • Metalloproteases
  • Prostatic Neoplasms
  • Biomarkers
  • PC-3 Cells
  6 Citations (Scopus)

• Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease

  Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M. & 98 others, Plia, M. G., Sala, C., Voelker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jorgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Raeikkoenen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., Den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Voelzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., Feb 2014, In : PLoS Genetics. 10, 2, p. 1-13 13 p., e1004123.

  Research output: Contribution to journal › Article

  Open Access
  98 Citations (Scopus)

• Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

  Schneider, C., Feller, M., Bauer, D. C., Collet, T. H., daCosta, B. R., Auer, R., Peeters, R. P., Brown, S. J., Bremner, A. P., O’Leary, P. C., Feddema, P., Leedman, P. J., Aujesky, D., Walsh, J. P. & Rodondi, N., 1 Apr 2018, In : PLoS One. 13, 4, e0196631.

  Research output: Contribution to journal › Article

  Open Access

  • Thyroid Gland
  • Reference Values
  • prediction
  • Testing
  • testing
  11 Citations (Scopus)

• Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines

  Price, K., Tsykin, A., Giles, K., Sladic, R. T., Epis, M., Ganss, R., Goodall, G. J. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 427, p. 343-348

  Research output: Contribution to journal › Article
  29 Citations (Scopus)

• microRNA-7: a tumor suppressor miRNA with therapeutic potential

  Kalinowski, F., Brown, R., Ganda, C., Giles, K. M., Epis, M., Horsham, J. & Leedman, P., Sep 2014, In : International Journal of Biochemistry and Cell Biology. 54, p. 312-317

  Research output: Contribution to journal › Article

  • Tumors
  • MicroRNAs
  • Neoplasms
  • Physiology
  • Untranslated RNA
  79 Citations (Scopus)

• microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-?B

  Giles, K., Brown, R. A., Ganda, C., Podgorny, M., Candy, P., Wintle, L. C., Richardson, K. L., Kalinowski, F. C., Stuart, L. M., Epis, M. R., Haass, N. K., Herlyn, M. & Leedman, P. J., 2016, In : Oncotarget. 7, 22, p. 31663-31680 18 p.

  Research output: Contribution to journal › Article

  Open Access

  • MicroRNAs
  • Melanoma
  • Cell Proliferation
  • Neoplasm Metastasis
  • ErbB Receptors
  46 Citations (Scopus)

• miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion

  Thomson, D., Giles, K., Maleki, S., Mreich, E., Wheeler, H., Leedman, P., Biggs, M., Cook, R., Little, N., Robinson, B., Mcdonald, K. & Fowler, A., 2011, In : European Journal of Cancer. 47, 6, p. 953-963

  Research output: Contribution to journal › Article
  99 Citations (Scopus)

• miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

  Epis, M. R., Giles, K. M., Beveridge, D. J., Richardson, K. L., Candy, P. A., Stuart, L. M., Bentel, J., Cohen, R. J. & Leedman, P. J., 2017, In : Oncotarget. 8, 33, p. 55116-55134 19 p.

  Research output: Contribution to journal › Article

  Open Access

  • Aurora Kinases
  • MicroRNAs
  • Prostatic Neoplasms
  • Carcinogenesis
  • Neoplasms
  14 Citations (Scopus)

• miR-331-3p regulates expression of neuropilin-2 in glioblastoma

  Epis, M., Giles, K., Candy, P., Webster, R. & Leedman, P., Jan 2014, In : Journal of Neuro-Oncology. 116, 1, p. 67-75

  Research output: Contribution to journal › Article

  Open Access

  • Neuropilin-2
  • Glioblastoma
  • Cell Line
  • Growth
  • Glioma
  51 Citations (Scopus)

• miRNA-7-5p inhibits melanoma cell migration and invasion

  Giles, K., Brown, R., Epis, M., Kalinowski, F. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 430, p. 706-710

  Research output: Contribution to journal › Article
  64 Citations (Scopus)

• Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes

  Singer, S., Zhao, R., Barsotti, A. M., Ouwehand, A., Fazollahi, M., Coutavas, E., Breuhahn, K., Neumann, O., Longerich, T., Pusterla, T., Powers, M. A., Giles, K., Leedman, P., Hess, J., Grunwald, D., Bussemaker, H. J., Singer, R. H., Schirmacher, P. & Prives, C., 2012, In : Molecular Cell. 48, p. 799-810

  Research output: Contribution to journal › Article

  Open Access
  43 Citations (Scopus)

• Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

  Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

  Research output: Contribution to journal › Article

  • Disintegrins
  • Metalloproteases
  • Prostatic Neoplasms
  • Pharmacology
  • Prostate
  9 Citations (Scopus)

• PRMT2 and RORy Expression Are Associated With Breast Cancer Survival Outcomes

  Oh, T. G., Bailey, P., Dray, E., Smith, A. G., Goode, J., Eriksson, N., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Clarke, C. L., Grimmond, S., Dowhan, D. H. & Muscat, G. E. O., 2014, In : Molecular Endocrinology. 28, p. 1166-1185

  Research output: Contribution to journal › Article

  27 Citations (Scopus)

• Protein arginine methyltransferase 6-dependent gene expression and splicing: association with breast cancer outcomes

  Dowhan, D. H., Harrison, M. J., Eriksson, N. A., Bailey, P., Pearen, M. A., Fuller, P. J., Funder, J. W., Simpson, E. R., Leedman, P., Tilley, W. D., Brown, M. A., Clarke, C. L. & Muscat, G. E. O., 2012, In : Endocrine-Related Cancer. 19, p. 509-526

  Research output: Contribution to journal › Article
  18 Citations (Scopus)

• Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7

  Kalinowski, F., Giles, K., Candy, P. A., Ali, A., Ganda, C., Epis, M., Webster, R. & Leedman, P., 24 Oct 2012, In : PLoS One. 7, p. 1-16

  Research output: Contribution to journal › Article

  Open Access

  • Erlotinib Hydrochloride
  • Head and Neck Neoplasms
  • ErbB Receptors
  • MicroRNAs
  • Untranslated Regions
  53 Citations (Scopus)

• Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of elF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells

  Epis, M., Giles, K., Kalinowski, F., Barker, A., Cohen, R. & Leedman, P., Oct 2012, In : Journal of Biological Chemistry. 287, p. 35251-35259

  Research output: Contribution to journal › Article

  Open Access

  • deoxyhypusine hydroxylase
  • Cells
  • Chemical activation
  • Prostatic Neoplasms
  • Enzymes
  40 Citations (Scopus)

• Sequence requirements for RNA binding by HuR and AUF1

  Barker, A., Epis, M., Porter, C. J., Hopkins, B. R., Wilce, M. C. J., Giles, K. & Leedman, P., 2012, In : Journal of Biochemistry. 151, p. 423-437

  Research output: Contribution to journal › Article
  43 Citations (Scopus)

• Significant association between thyroid hormones and erythrocyte indices in euthyroid subjects

  Bremner, A., Feddema, P., Joske, D., Leedman, P., O'Leary, P., Olynyk, J. & Walsh, J., 2012, In : Clinical Endocrinology. 76, p. 304-311

  Research output: Contribution to journal › Article
  35 Citations (Scopus)

• The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

  Brown, S. J., Bremner, A., Hadlow, N. C., Feddema, P., Leedman, P., O'Leary, P. & Walsh, J., Nov 2016, In : Clinical Endocrinology. 85, 5, p. 789-796

  Research output: Contribution to journal › Article

  Open Access

  • Iodide Peroxidase
  • Smoking
  • Sigmoid Colon
  • Antibodies
  • Linear Models
  22 Citations (Scopus)

• The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

  Epis, M., Barker, A. P., Giles, K., Beveridge, D. & Leedman, P., 2011, In : The Journal of Biological Chemistry. 286, 48, p. 41442-41454

  Research output: Contribution to journal › Article
  66 Citations (Scopus)

• Total RNA extraction from tissues for microRNA and target gene expression analysis: Not all kits are created equal

  Brown, R. A. M., Epis, M. R., Horsham, J. L., Kabir, T. D., Richardson, K. L. & Leedman, P. J., 16 Mar 2018, In : BMC Biotechnology. 18, 1, 16.

  Research output: Contribution to journal › Article

  Open Access

  • MicroRNAs
  • RNA
  • Gene Expression
  • Phenol
  • Chloroform
  27 Citations (Scopus)

• Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development

  Woo, A., Patry, C-A. A., Ghamari, A., Pregernig, G., Yuan, D., Zheng, K., Piers, T., Hibbs, M., Li, J. K., Fidalgo, M., Wang, J. Y., Lee, J-H., Leedman, P., Wang, J., Fraenkel, E. & Cantor, A. B., 27 Aug 2019, In : Blood advances. 3, 16, p. 2499-2511 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Erythroid Cells
  • Erythropoiesis
  • Transcription Factors
  • GATA1 Transcription Factor
  • Hypochromic microcytic Anemia
• Chapter

  Evaluation of microRNA delivery in vivo

  Brown, R. A. M., Richardson, K. L., Kalinowski, F. C., Epis, M. R., Horsham, J. L., Kabir, T. D., De Pinho, M. H., Beveridge, D. J., Stuart, L. M., Wintle, L. C. & Leedman, P. J., 2018, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 2nd ed. Humana Press, Vol. 1699. p. 155-178 24 p. (Methods in Molecular Biology; vol. 1699).

  Research output: Chapter in Book/Conference paper › Chapter

  • MicroRNAs
  • Oncogenes
  • Animal Structures
  • Neoplasms
  • Small Untranslated RNA
  8 Citations (Scopus)
• Letter

  A case of iatrogenic cushing syndrome and apparent mineralocorticoid excess presenting with accelerated hypertension and proteinuria

  Kong, W. Y., Leedman, P. & Irish, A., 2014, In : Internal Medicine Journal. 44, 9, p. 932-934

  Research output: Contribution to journal › Letter
• Other chapter contribution

  MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells

  Giles, K., Barker, A. P., Zhang, P., Epis, M. & Leedman, P., 2011, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 1st Edition ed. United States: Humana Press, p. 147-163

  Research output: Chapter in Book/Conference paper › Other chapter contribution

  30 Citations (Scopus)
• Review article

  Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology

  Brown, R. A. M., Richardson, K. L., Kabir, T. D., Trinder, D., Ganss, R. & Leedman, P. J., 9 Apr 2020, In : Frontiers in Oncology. 10, 476.

  Research output: Contribution to journal › Review article

  Open Access

  • Allergy and Immunology
  • Iron
  • Neoplasm Metastasis
  • Neoplasms
  • Iron Chelating Agents
  6 Citations (Scopus)

• MicroRNA-7: A miRNA with expanding roles in development and disease

  Horsham, J., Ganda, C., Kalinowski, F., Brown, R., Epis, M. & Leedman, P., 2015, In : International Journal of Biochemistry and Cell Biology. 69, p. 215-224

  Research output: Contribution to journal › Review article

  • MicroRNAs
  • mouse MIRN7 microRNA
  • Molecules
  • Health
  • Untranslated RNA
  47 Citations (Scopus)

• Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer

  Vos, P. D., Leedman, P. J., Filipovska, A. & Rackham, O., Oct 2019, In : Cellular and Molecular Life Sciences. 76, 19, p. 3745–3752

  Research output: Contribution to journal › Review article

  • RNA-Binding Proteins
  • MicroRNAs
  • Neoplasms
  • Synthetic Biology
  • RNA Stability
  12 Citations (Scopus)