Find Research outputs

Search results

• Article

  Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function

  Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

  Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Haritunians, T., Jostins, L., Latiano, A., Mathew, C. G., Montgomery, G. W., Prescott, N. J., Rotter, J. I., Schumm, P., Sharma, Y., Simms, L. A., Taylor, K. D., Whiteman, D., Wijmenga, C., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Bunning, C., Cohen, A., Colombel, J-F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S. L., Halfvarson, J., Hommes, D., Hugot, J-P., Laukens, D., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D. D., Regueiro, M., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A. H., Stokkers, P. C. F., Torkvist, L., Kullak-Ublick, G., Walters, T., Targan, S. R., Brant, S. R., Rioux, J. D., D'Amato, M., Weersma, R., Kutharthasan, S., Griffiths, A. M., Mansfield, J. C., Vermeire, S., Duerr, R. H., Silverberg, M. S., Satsangi, J., Schreiber, S., Cho, J. H., Annese, V., Hakonarson, H. & Parkes, M., 2011, In : PLoS Genetics. 7, 1, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  349 Citations (Scopus)

• Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study

  Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193

  Research output: Contribution to journal › Article
  99 Citations (Scopus)

• Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study

  Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606

  Research output: Contribution to journal › Article

  • Patient Acceptance of Health Care
  • Ulcerative Colitis
  • Health Care Costs
  • Observational Studies
  • Cross-Sectional Studies
  64 Citations (Scopus)

• Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis

  Ng, Y. L., Klopcic, B., Lloyd, F., Forrest, C., Greene, W. & Lawrance, I., 2013, In : PLoS One. 8, 10, p. 8pp

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• Serologic antibodies in relation to outcome in postoperative Crohn's disease

  Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, Selby, W., Bell, S. J., Brown, S. J. & Connell, W. R., 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.

  Research output: Contribution to journal › Article

  • Crohn Disease
  • Recurrence
  • Antibodies
  • Anti-Idiotypic Antibodies
  • Bacterial Antibodies
  9 Citations (Scopus)

• SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer

  Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  45 Citations (Scopus)

• The multidisciplinary team

  Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17

  Research output: Contribution to journal › Article
  2 Citations (Scopus)

• Topical agents for idiopathic distal colitis and proctitis

  Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43

  Research output: Contribution to journal › Article
  19 Citations (Scopus)

• Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

  Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.

  Research output: Contribution to journal › Article

  Open Access

  • vitamin D
  • Microbiota
  • microbiome
  • Vitamin D
  • colitis
  14 Citations (Scopus)

• Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD

  Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371

  Research output: Contribution to journal › Article

  8 Citations (Scopus)

• Vedolizumab as induction and maintenance therapy for Crohn's disease

  GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.

  Research output: Contribution to journal › Article

  • vedolizumab
  • Crohn Disease
  • Placebos
  • Therapeutics
  • Nasopharyngitis
  1048 Citations (Scopus)

• Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford

  Pulusu, S. S. R., Srinivasan, A., Krishnaprasad, K., Cheng, D., Begun, J., Keung, C., van Langenberg, D., Thin, L., Mogilevski, T., De Cruz, P., Radford-Smith, G., Flanagan, E., Bell, S., Kashkooli, S., Sparrow, M. P., Ghaly, S., Bampton, P. A., Sawyer, E., Connor, S., Rizvi, Q-U-A. & 4 others, Andrews, J. M., Mahy, G., Chivers, P. & Lawrance, I., 14 Aug 2020, In : World Journal of Gastroenterology. 26, 30, p. 4428-4441

  Research output: Contribution to journal › Article

  Open Access

  • vedolizumab
  • Ulcerative Colitis
  • integrin beta7
  • Integrin alpha4
  • Antibodies, Monoclonal, Humanized

• Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission

  Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Crohn Disease
  • Vitamin D
  • Vitamin D-Binding Protein
  • Inflammation
  • 25-hydroxyvitamin D

• What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

  Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258

  Research output: Contribution to journal › Article

  Open Access

  • Inflammatory Bowel Diseases
  • Tumor Necrosis Factor-alpha
  • Mercaptopurine
  • Physicians
  • Mycophenolic Acid
  9 Citations (Scopus)
• Conference presentation/ephemera

  A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis

  Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.

  Research output: Contribution to conference › Conference presentation/ephemera
• Editorial

  Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements

  Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.

  Research output: Contribution to journal › Editorial

  Open Access
  33 Citations (Scopus)
• Letter

  PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease

  Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)
• Review article

  Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program

  Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465

  Research output: Contribution to journal › Review article

• Dysplasia and colorectal cancer surveillance in inflammatory bowel disease

  Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Colorectal Neoplasms
  • Mesalamine
  • Needs Assessment
  • Chemoprevention
  9 Citations (Scopus)

• Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome

  Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.

  Research output: Contribution to journal › Review article

  • Ultraviolet Rays
  • Microbiota
  • Inflammatory Bowel Diseases
  • Vitamin D
  • Gastrointestinal Microbiome
  1 Citation (Scopus)

• Mechanisms of initiation and progression of intestinal fibrosis in IBD

  Latella, G., Di Gregorio, J., Flati, V., Rieder, F. & Lawrance, I., 2014, In : Scandinavian Journal of Gastroenterology. 50, p. 53-65

  Research output: Contribution to journal › Review article
  78 Citations (Scopus)

• Microbiota and management of inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140

  Research output: Contribution to journal › Review article
  3 Citations (Scopus)

• Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984

  Research output: Contribution to journal › Review article
  5 Citations (Scopus)

• Preventing infective complications in inflammatory bowel disease

  Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698

  Research output: Contribution to journal › Review article

  Open Access

  • Inflammatory Bowel Diseases
  • Opportunistic Infections
  • Physicians
  • Biological Factors
  • Patient Education
  9 Citations (Scopus)

• Prevention of cancer in IBD - A balancing act

  Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Inflammation
  • Immunosuppression
  • Lymphoma
  • Colorectal Neoplasms
  7 Citations (Scopus)

• Prevention of cancer in IBD – a balancing act

  Lawrance, I., Sep 2013, In : Minerva Gastroenterologica e Dietologica.

  Research output: Contribution to journal › Review article

• Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD

  Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165

  Research output: Contribution to journal › Review article

  • Colitis
  • Inflammatory Bowel Diseases
  • Fibrosis
  • Education
  • Tissue Inhibitor of Metalloproteinases
  96 Citations (Scopus)

• The importance of validating proposed genetic profiles in IBD

  Lawrance, I., May 2014, In : Journal of Internal Medicine.

  Research output: Contribution to journal › Review article

• The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases

  Grosse, C. S. J., Christophersen, C. T., Devine, A. & Lawrance, I. C., 3 Mar 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 3, p. 137-145 9 p.

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Diet
  • Symbiosis
  • Diet Therapy
  • Expert Testimony
  2 Citations (Scopus)

• The role of vitamin D in gastrointestinal inflammation

  Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923

  Research output: Contribution to journal › Review article

  • Vitamin D
  • Inflammation
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Adaptive Immunity
  26 Citations (Scopus)