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  • Jiake Xu
Short survey

Connecting Versatile lncRNAs with Heterogeneous Nuclear Ribonucleoprotein K and Pathogenic Disorders

Zhu, S., Wang, Z. & Xu, J., 1 Sep 2019, In : Trends in Biochemical Sciences. 44, 9, p. 733-736 4 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)

Zhao, D., Zhang, F., Wang, B., Liu, B., Li, L., Kim, S. Y., Goodman, S. B., Hernigou, P., Cui, Q., Lineaweaver, W. C., Xu, J., Drescher, W. R. & Qin, L., Mar 2020, In : Journal of Orthopaedic Translation. 21, p. 100-110 11 p.

Research output: Contribution to journalShort survey

Open Access
4 Citations (Scopus)
Review article

Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human

Yuan, J., Tickner, J., Mullin, B. H., Zhao, J., Zeng, Z., Morahan, G. & Xu, J., 2 Apr 2019, In : Frontiers in Genetics. 10, 13 p., 288.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease

Zhu, S., Qiu, H., Bennett, S., Kuek, V., Rosen, V., Xu, H. & Xu, J., Nov 2019, In : Cellular and Molecular Life Sciences. 76, 22, p. 4493-4502

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Current research on pharmacologic and regenerative therapies for osteoarthritis

Zhang, W., Ouyang, H., Dass, C. R. & Xu, J., 1 Mar 2016, In : Bone Research. 4, p. 1-14 14 p., 15040 .

Research output: Contribution to journalReview article

Open Access
145 Citations (Scopus)

EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis

Hong, G., Kuek, V., Shi, J., Zhou, L., Han, X., He, W., Tickner, J., Qiu, H., Wei, Q. & Xu, J., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8526-8537 12 p.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
307 Downloads (Pure)

Emerging Trend in the Pharmacotherapy of Osteoarthritis

Zhang, W., Robertson, W. B., Zhao, J., Chen, W. & Xu, J., 2 Jul 2019, In : Frontiers in Endocrinology. 10, 9 p., 431.

Research output: Contribution to journalReview article

Open Access
12 Citations (Scopus)

Endothelial cells produce angiocrine factors to regulate bone and cartilage via versatile mechanisms

Zhu, S., Bennett, S., Kuek, V., Xiang, C., Xu, H., Rosen, V. & Xu, J., 1 May 2020, In : Theranostics. 10, 13, p. 5957-5965 9 p.

Research output: Contribution to journalReview article

Open Access

Massage alleviates delayed onset muscle soreness after strenuous exercise: A systematic review and meta-analysis

Guo, J., Li, L., Gong, Y., Zhu, R., Xu, J., Zou, J. & Chen, X., 27 Sep 2017, In : Frontiers in Physiology. 8, 747.

Research output: Contribution to journalReview article

Open Access
11 Citations (Scopus)

MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases

Li, H., Zhai, Z., Qu, X., Xu, J., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 422-431 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Molecular structure, expression, and functional role of Clec11a in skeletal biology and cancers

Wang, M., Guo, J., Zhang, L., Kuek, V., Xu, J. & Zou, J., 1 Oct 2020, In : Journal of Cellular Physiology. 235, 10, p. 6357-6365 9 p.

Research output: Contribution to journalReview article

Molecular structure and differential function of choline kinases CHKα and CHKβ in musculoskeletal system and cancer

Chen, X., Qiu, H., Wang, C., Yuan, Y., Tickner, J., Xu, J. & Zou, J., Feb 2017, In : Cytokine and Growth Factor Reviews. 33, p. 65-72 8 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
295 Downloads (Pure)

Molecular structure and the role of high-temperature requirement protein 1 in skeletal disorders and cancers

Li, Y., Yuan, J., Rothzerg, E., Wu, X., Xu, H., Zhu, S. & Xu, J., 22 Dec 2019, In : Cell Proliferation. e12746.

Research output: Contribution to journalReview article

Open Access

Pathological mechanisms and therapeutic outlooks for arthrofibrosis

Usher, K. M., Zhu, S., Mavropalias, G., Carrino, J. A., Zhao, J. & Xu, J., 1 Dec 2019, In : Bone Research. 7, 1, 9.

Research output: Contribution to journalReview article

Open Access
10 Citations (Scopus)

Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease

Zhu, S., Kuek, V., Bennett, S., Xu, H., Rosen, V. & Xu, J., 14 May 2019, In : Cellular and Molecular Life Sciences. 76, 18, p. 3515-3523

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Rheumatoid arthritis: Pathological mechanisms and modern pharmacologic therapies

Guo, Q., Wang, Y., Xu, D., Nossent, J., Pavlos, N. J. & Xu, J., 1 Dec 2018, In : Bone Research. 6, 1, 16.

Research output: Contribution to journalReview article

Open Access
138 Citations (Scopus)

Roles of neurotrophins in skeletal tissue formation and healing

Su, Y. W., Zhou, X. F., Foster, B. K., Grills, B. L., Xu, J. & Xian, C. J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis

Tong, X., Chen, X., Zhang, S., Huang, M., Shen, X., Xu, J. & Zou, J., 2019, In : BioMed Research International. 2019, 8 p., 8171897.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

The emerging role of Hippo signaling pathway in regulating osteoclast formation

Yang, W., Han, W., Qin, A., Wang, Z., Xu, J. & Qian, Y., 1 Jun 2018, In : Journal of Cellular Physiology. 233, 6, p. 4606-4617 12 p.

Research output: Contribution to journalReview article

17 Citations (Scopus)

The emerging role of NPNT in tissue injury repair and bone homeostasis

Sun, Y., Kuek, V., Qiu, H., Tickner, J., Chen, L., Wang, H., He, W. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 1887-1894 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

The emerging roles of hnRNPK

Wang, Z., Qiu, H., He, J., Liu, L., Xue, W., Fox, A., Tickner, J. & Xu, J., 19 Sep 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Therapeutic potential and outlook of alternative medicine for osteoporosis

Wang, T., Liu, Q., Tjhioe, W., Zhao, J., Lu, A., Zhang, G., Tan, R. X., Zhou, M., Xu, J. & Feng, H. T., 1 Jul 2017, In : Current Drug Targets. 18, 9, p. 1051-1068 18 p.

Research output: Contribution to journalReview article

28 Citations (Scopus)

The role of glial cell line-derived neurotrophic factor family member artemin in neurological disorders and cancers

Zhu, S., Li, Y., Bennett, S., Chen, J., Weng, I. Z., Huang, L., Xu, H. & Xu, J., 1 Jul 2020, In : Cell Proliferation. 53, 7, e12860.

Research output: Contribution to journalReview article

Open Access

Zoledronic Acid: Pleiotropic Anti-tumor Mechanism and Therapeutic Outlook for Osteosarcoma

Ouyang, Z., Li, H., Zhai, Z., Xu, J., Dass, C. R., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 409-421 13 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
Article

A005, a novel inhibitor of phosphatidylinositol 3-kinase/mammalian target of rapamycin, prevents osteosarcoma-induced osteolysis

Lian, Z., Han, J., Huang, L., Wei, C., Fan, Y., Xu, J., Zhou, M., Feng, H., Liu, Q., Chen, L., Li, Z., Cheng, H., Yuan, G., Lin, X., Song, F., Su, Y., Wang, C., Huang, G., Qin, A., Song, Y. & 1 others, Yao, G., 1 Jan 2019, In : Carcinogenesis. 40, 2, p. E1-E13

Research output: Contribution to journalArticle

3 Citations (Scopus)

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Song, D., Cao, Z., Huang, S., Tickner, J., Li, N., Qiu, H., Chen, X., Wang, C., Chen, K., Sun, Y., Dong, S. & Xu, J., 1 Jun 2018, In : Journal of Cellular Biochemistry. 119, 6, p. 4826-4835 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
347 Downloads (Pure)

Amyloid β peptide enhances RANKL-induced osteoclast activation through NF-κB, ERK, and calcium oscillation signaling

Li, S., Yang, B., Teguh, D., Zhou, L., Xu, J. & Rong, L., 1 Oct 2016, In : International Journal of Molecular Sciences. 17, 10, 1683.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Analysis of circulating microRNAs aberrantly expressed in alcohol-induced osteonecrosis of femoral head

Hong, G., Han, X., He, W., Xu, J., Sun, P., Shen, Y., Wei, Q. & Chen, Z., 1 Dec 2019, In : Scientific Reports. 9, 1, 18926.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

A polyamidoamne dendrimer functionalized graphene oxide for DOX and MMP-9 shRNA plasmid co-delivery

Gu, Y., Guo, Y., Wang, C., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Jan 2017, In : Materials Science and Engineering C. 70, p. 572-585 14 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation

Chen, D., Ye, Z., Wang, C., Wang, Q., Wang, H., Kuek, V., Wang, Z., Qiu, H., Yuan, J., Kenny, J., Yang, F., He, J., Liu, Y., Wang, G., Zhang, M., Zhang, G., Wang, J., Chen, P. & Xu, J., Sep 2020, In : Pharmacological Research. 159, 104944.

Research output: Contribution to journalArticle

Artesunate inhibits RANKL-induced osteoclastogenesis and bone resorption in vitro and prevents LPS-induced bone loss in vivo

Wei, C. M., Liu, Q., Song, F. M., Lin, X. X., Su, Y. J., Xu, J., Huang, L., Zong, S. H. & Zhao, J. M., 1 Jan 2018, In : Journal of Cellular Physiology. 233, 1, p. 476-485 10 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca2+–NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

Zeng, X., Zhang, Y., Wang, S., Wang, K., Tao, L., Zou, M., Chen, N., Xu, J., Liu, S. & Li, X., 15 Jan 2017, In : Biochemical Pharmacology. 124, p. 57-68 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways

Hong, G., Zhou, L., Han, X., Sun, P., Chen, Z., He, W., Tickner, J., Chen, L., Shi, X. & Xu, J., 27 Mar 2020, In : Frontiers in Pharmacology. 11, 331.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-kappa B signaling pathways

He, L., Hong, G., Zhou, L., Zhang, J., Fang, J., He, W., Tickner, J., Han, X., Zhao, L. & Xu, J., Apr 2019, In : Journal of Cellular Physiology. 234, 4, p. 4267-4276 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Asperpyrone A attenuates RANKL-induced osteoclast formation through inhibiting NFATc1, Ca2+ signalling and oxidative stress

Chen, X., Wang, C., Qiu, H., Yuan, Y., Chen, K., Cao, Z., Xiang Tan, R., Tickner, J., Xu, J. & Zou, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8269-8279 11 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis

Jin, H., Wang, Q., Chen, K., Xu, K., Pan, H., Chu, F., Ye, Z., Wang, Z., Tickner, J., Qiu, H., Wang, C., Kenny, J., Xu, H., Wang, T. & Xu, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8355-8368 14 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
5 Citations (Scopus)

Bajijiasu abrogates osteoclast differentiation via the suppression of RANKL signaling pathways through NF-κB and NFAT

Hong, G., Zhou, L., Shi, X., He, W., Wang, H., Wei, Q., Chen, P., Qi, L., Tickner, J., Lin, L. & Xu, J., 19 Jan 2017, In : International Journal of Molecular Sciences. 18, 1, 12 p., 203.

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways

Wei, J., Li, Y., Liu, Q., Lan, Y., Wei, C., Tian, K., Wu, L., Lin, C., Xu, J., Zhao, J. & Yang, Y., 7 Jul 2020, In : Frontiers in Pharmacology. 11, 1025.

Research output: Contribution to journalArticle

Open Access

Biocompatibility and cellular uptake mechanisms of poly(N -isopropylacrylamide) in different cells

Guo, Z., Li, S., Wang, C., Xu, J., Kirk, B., Wu, J., Liu, Z. & Xue, W., 1 Jan 2017, In : Journal of Bioactive and Compatible Polymers. 32, 1, p. 17-31 15 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Biocompatible hyperbranched polyglycerol modified β-cyclodextrin derivatives for docetaxel delivery

Xu, Z., Zhang, Y., Hu, Q., Tang, Q., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Feb 2017, In : Materials Science and Engineering C. 71, p. 965-972 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cajaninstilbene acid inhibits osteoporosis through suppressing osteoclast formation and RANKL-induced signaling pathways

Sun, Y., Liu, Y., He, W., Wang, C., Tickner, J., Kuek, V., Zhou, C., Wang, H., Zou, X., Hong, Z., Yang, F., Shao, M., Chen, L. & Xu, J., 1 Jul 2019, In : Journal of Cellular Physiology. 234, 7, p. 11792-11804 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Calmodulin interacts with Rab3D and modulates osteoclastic bone resorption

Zhu, S., Chim, S. M., Cheng, T., Ang, E., Ng, B., Lim, B., Chen, K., Qiu, H., Tickner, J., Xu, H., Pavlos, N. & Xu, J., 29 Nov 2016, In : Scientific Reports. 6, p. 1-9

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Carnosic acid inhibits inflammation response and joint destruction on osteoclasts, fibroblast-like synoviocytes, and collagen-induced arthritis rats

Liu, M., Zhou, X., Zhou, L., Liu, Z., Yuan, J., Cheng, J., Zhao, J., Wu, L., Li, H., Qiu, H. & Xu, J., 1 Aug 2018, In : Journal of Cellular Physiology. 233, 8, p. 6291-6303 13 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Cepharanthine suppresses osteoclast formation by modulating the nuclear factor-κB and nuclear factor of activated T-cell signaling pathways

Lin, X., Song, F., Zhou, L., Wang, Z., Wei, C., Xu, J., Zhao, J. & Liu, Q., 1 Feb 2019, In : Journal of Cellular Biochemistry. 120, 2, p. 1990-1996 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
64 Downloads (Pure)

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

Mullin, B., Tickner, J., Zhu, K., Kenny, J., Mullin, S., Brown, S. J., Dudbridge, F., Pavlos, N., Mocarski, E. S., Walsh, J. P., Xu, J. & Wilson, S., 26 Mar 2020, In : Genome Biology. 21, 1, 80.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

CHIP/Stub1 regulates the Warburg effect by promoting degradation of PKM2 in ovarian carcinoma

Shang, Y., He, J., Wang, Y., Feng, Q., Zhang, Y., Guo, J., Li, J., Li, S., Wang, Y., Yan, G., Ren, F., Shi, Y., Xu, J., Zeps, N., Zhai, Y., He, D. & Chang, Z., 20 Jul 2017, In : Oncogene. 36, 29, p. 4191-4200 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Cistanche deserticola polysaccharide attenuates osteoclastogenesis and bone resorption via inhibiting RANKL signaling and reactive oxygen species production

Song, D., Cao, Z., Liu, Z., Tickner, J., Qiu, H., Wang, C., Chen, K., Wang, Z., Dong, S. & Xu, J., 1 Dec 2018, In : Journal of Cellular Physiology. 233, 12, p. 9674-9684 11 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
164 Downloads (Pure)

Conditional Knockout of PKC-δ in Osteoclasts Favors Bone Mass Accrual in Males Due to Decreased Osteoclast Function

Li, S., He, T., Wu, D., Zhang, L., Chen, R., Liu, B., Yuan, J., Tickner, J., Qin, A., Xu, J. & Rong, L., 9 Jun 2020, In : Frontiers in Cell and Developmental Biology. 8, 450.

Research output: Contribution to journalArticle

Open Access