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• Review article

  A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2018, In : Frontiers of Medicine. 5, 135.

  Research output: Contribution to journal › Review article

  Open Access

  • Microbiota
  • Obesity
  • Dysbiosis
  • Noncommunicable Diseases
  • Maternal Age
  45 Citations (Scopus)

• A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)

• Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  42 Citations (Scopus)

• Measurement of androgen and estrogen concentrations in cord blood: Accuracy, biological interpretation, and applications to understanding human behavioral development

  Hollier, L. P., Keelan, J., Hickey, M., Maybery, M. & Whitehouse, A., 2014, In : Frontiers in Endocrinology. 5, MAY, p. 64

  Research output: Contribution to journal › Review article

  Open Access
  38 Citations (Scopus)

• Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)

• Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)

• Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  59 Citations (Scopus)

• Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)

• Role of Wnt signalling in early pregnancy

  Nayeem, S., Arfuso, F., Dharmarajan, A. & Keelan, J., 2014, In : Reproduction, Fertility and Development. accepted 5 August 2014, published online 5 September 2014, p. doi: 10.1071/RD14079

  Research output: Contribution to journal › Review article
  10 Citations (Scopus)

• Toll-like receptor-4: A new target for preterm labour pharmacotherapies?

  Robertson, S. A., Wahid, H. H., Chin, P. Y., Hutchinson, M. R., Moldenhauer, L. M. & Keelan, J. A., 2018, In : Current Pharmaceutical Design. 24, 9, p. 960-973

  Research output: Contribution to journal › Review article

  • Premature Obstetric Labor
  • Toll-Like Receptor 4
  • Premature Birth
  • Drug Therapy
  • Uterine Cervical Diseases
  9 Citations (Scopus)
• Literature review

  Strategies to prevent preterm birth

  Newnham, J., Dickinson, J., Hart, R., Pennell, C., Arrese, C. & Keelan, J., 2014, In : Frontiers in Immunology. 5, p. 1-12

  Research output: Contribution to journal › Literature review

  Open Access
  50 Citations (Scopus)
• Letter

  ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)

• Letter to the editor: “Fatty acids and placental transport: Insight or in vitro artifact?”

  Keelan, J., 2014, In : American Journal of Physiology - Cell Physiology. 307, 11, p. C1068

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)

• Re-analysis of the association between perinatal androgens and postnatal head circumference growth

  Whitehouse, A., Maybery, M., Hart, R., Sloboda, D. M., Newnham, J., Stanley, F., Hickey, M. & Keelan, J., 2014, In : Developmental Medicine and Child Neurology. 56, p. 1025

  Research output: Contribution to journal › Letter

• Re-analysis of the association between perinatal androgens and pragmatic language ability

  Whitehouse, A., Maybery, M., Hart, R., Mattes, E., Newnham, J., Sloboda, D. M., Keelan, J. & Hickey, M., 2014, In : Psychoneuroendocrinology. 49, p. 32-33

  Research output: Contribution to journal › Letter

  1 Citation (Scopus)
• Edited book/Anthology

  Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology
• Conference paper

  Amniotic fluid cytokine concentrations at 2nd trimester amniocentesis and pregnancy outcomes in Australian and Chinese cohorts

  Li, S., Feng, Z., Payne, M., Jie, L., Doherty, D., Biyun, X., Lenan, L., Yihua, Z., Dickinson, J., Keelan, J., Yali, H. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 244A

  Research output: Chapter in Book/Conference paper › Conference paper

• Detection of bacterial DNA in amniotic fluid. Is there an association with elevated cytokine levels and pregnancy outcome?

  Payne, M., Li, S., Doherty, D., Keelan, J. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 112A

  Research output: Chapter in Book/Conference paper › Conference paper

• In vitro maturation (IVM) with a freeze-all embryo protocol may benefit patients with polycystic ovarian syndrome (PCOS)

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, E. & Hart, R., 2014, American Society for Reproductive Medicine. United States: Elsevier, Vol. 102. p. e201

  Research output: Chapter in Book/Conference paper › Conference paper

• Maternal-amniotic-fetal azithromycin pharmacokinetics in a sheep model of second trimester pregnancy

  Kemp, M., Keelan, J., Miura, Y., Payne, M., Saito, M., Clarke, M., Stock, S., Spiller, B., Watts, R., Yaegashi, N., Jobe, AH. & Newnham, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 240A

  Research output: Chapter in Book/Conference paper › Conference paper

• Maternal intravenous treatment with either azithromycin or solithromycin clears Ureaplasma from the amniotic fluid in an ovine model of intrauterine infection

  Miura, Y., Payne, M., Keelan, J., Noe, A., Carter, S., Watts, R., Spiller, B., Jobe, A., Stock, S., Newnham, J. & Kemp, M., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 249A

  Research output: Chapter in Book/Conference paper › Conference paper

• Role of secreted Wnt signaling inhibitors in cross-talk between trophoblast and decidual cells in co-culture

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 294-5A

  Research output: Chapter in Book/Conference paper › Conference paper

• TAK1 inhibition for the prevention of inflammation-induced preterm birth

  Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Targeting inflammatory pathways with intra-amniotic CSAIDs for the prevention of preterm birth

  Ireland, D., Stinson, L., Charles, A., Kemp, M., Newnham, E. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

  Research output: Chapter in Book/Conference paper › Conference paper

• Whole blood flow cytometric analysis of Ureaplasma-stimulated T-cells from pregnant women

  Ireland, D., Friedland, Y. D., Lee-Pullen, T. F., Payne, M. & Keelan, J., 2014, Reproductive Sciences. United States: SAGE Publications Ltd, Vol. 21. p. 237A

  Research output: Chapter in Book/Conference paper › Conference paper
• Article

  Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

  Hollier, L. P., Keelan, J., Jamnadass, E., Maybery, M., Hickey, M. & Whitehouse, A., Feb 2015, In : Early Human Development. 91, 2, p. 111-117 7 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Umbilical Cord
  • Androgens
  • Estrogens
  • Fetal Blood
  • Testosterone
  37 Citations (Scopus)

  505 Downloads (Pure)

• Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

  Keelan, J., Mattes, E., Tan, H., Dinan, A., Newnham, J., Whitehouse, A., Jacoby, P. & Hickey, M., 20 Aug 2012, In : PLoS One. 7, 8, p. e42827.1-10

  Research output: Contribution to journal › Article

  Open Access

  • Fetal Blood
  • Androgens
  • Obstetrics
  • Testosterone
  • Mothers
  54 Citations (Scopus)

• Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

  Beaudry-Richard, A., Nadeau-Vallée, M., Prairie, É., Maurice, N., Heckel, É., Nezhady, M., Pundir, S., Madaan, A., Boudreault, A., Hou, X., Quiniou, C., Sierra, E. M., Beaulac, A., Lodygensky, G., Robertson, S. A., Keelan, J., Adams-Waldorf, K., Olson, D. M., Rivera, J. C., Lubell, W. D. & 3 others, Joyal, J. S., Bouchard, J. F. & Chemtob, S., 8 Aug 2018, In : Scientific Reports. 8, 1, 11875.

  Research output: Contribution to journal › Article

  Open Access

  • Interleukin-1
  • Inflammation
  • Chorioamnionitis
  • Hyperoxia
  • Retinal Vessels
  8 Citations (Scopus)

• A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)

  Payne, M. S., Newnham, J. P., Doherty, D. A., Furfaro, L. L., Pendal, N. L., Loh, D. E. & Keelan, J. A., 27 Aug 2020, In : American Journal of Obstetrics and Gynecology.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Vagina
  • Premature Birth
  • Ureaplasma
  • Lactobacillus

• Ceramide biosynthesis and metabolism in trophoblast syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Molecular and Cellular Endocrinology. 362, p. 48 - 59

  Research output: Contribution to journal › Article
  11 Citations (Scopus)

• Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Wang, C., Newnham, J. & Pennell, C., Nov 2015, In : Journal of Reproductive Immunology. 112, p. 1-10 10 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Gingival Crevicular Fluid
  • Periodontal Diseases
  • Pregnancy Outcome
  • Pregnancy
  • Interleukin-1
  17 Citations (Scopus)

  376 Downloads (Pure)

• Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  7 Citations (Scopus)

• Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

  Stinson, L., Hallingström, M., Barman, M., Viklund, F., Keelan, J., Kacerovsky, M., Payne, M. & Jacobsson, B., 24 Mar 2020, In : Frontiers in Microbiology. 11, 415.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Amniotic Fluid
  • rRNA Genes
  • DNA Contamination
  • Technology
  4 Citations (Scopus)

• Comparison of Meconium DNA extraction methods for use in microbiome studies

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 20 Feb 2018, In : Frontiers in Microbiology. 9, FEB, 270.

  Research output: Contribution to journal › Article

  Open Access

  • Meconium
  • Microbiota
  • DNA
  • Bacterial DNA
  • Polymerase Chain Reaction
  16 Citations (Scopus)

• Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)

• Development of a model for functional studies of ABCG2 (breast cancer resistance protein) efflux employing a standard BeWo clone (B24)

  Keelan, J. & Crowe, A., 2012, In : Assay and Drug Development Technologies. 10, p. 476 - 484

  Research output: Contribution to journal › Article
  4 Citations (Scopus)

• Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  38 Citations (Scopus)

• Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  284 Downloads (Pure)

• Effects of cytokine-suppressive anti-inflammatory drugs on inflammatory activation in ex vivo human and ovine fetal membranes

  Stinson, L., Ireland, D., Kemp, M., Payne, M., Stock, S., Newnham, J. & Keelan, J., 1 Mar 2014, In : Reproduction. 147, 3, p. 313-320

  Research output: Contribution to journal › Article

  Open Access

  File

  • Extraembryonic Membranes
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Sheep
  • Dinoprostone
  • Anti-Inflammatory Agents
  19 Citations (Scopus)

  308 Downloads (Pure)

• Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

  Yang, H., Sun, C., Fan, Z., Tian, X., Yan, L., Du, L., Liu, Y., Chen, C., Liang, X., Anderson, GJ., Keelan, J., Zhao, Y. & Nie, G., 2012, In : Scientific Reports. 2, p. 847 - 854

  Research output: Contribution to journal › Article

  Open Access
  88 Citations (Scopus)

• Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)

• Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice

  Yang, H., Du, L., Tian, X., Fan, Z., Sun, C., Liu, Y., Keelan, J. & Nie, G., 2014, In : Toxicology Letters. 230, 1, p. 10-18

  Research output: Contribution to journal › Article

  • Gold nanoparticles
  • Toxicity
  • Gold
  • Nanoparticles
  • Gestational Age
  35 Citations (Scopus)

• Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)

• Fetal Testosterone, Socio-Emotional Engagement and Language Development

  Farrant, B., Mattes, E., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Infant and Child Development. 22, 2, p. 119-132

  Research output: Contribution to journal › Article
  9 Citations (Scopus)

• High-resolution melt PCR analysis for genotyping of Ureaplasma parvum isolates directly from clinical samples

  Payne, M. S., Tabone, T., Kemp, M. W., Keelan, J. A., Spiller, O. B. & Newnham, J. P., Feb 2014, In : Journal of Clinical Microbiology. 52, 2, p. 599-606 8 p.

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  20 Citations (Scopus)

• IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)

• Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)