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  • Jiake Xu
Short survey

Connecting Versatile lncRNAs with Heterogeneous Nuclear Ribonucleoprotein K and Pathogenic Disorders

Zhu, S., Wang, Z. & Xu, J., 1 Sep 2019, In : Trends in Biochemical Sciences. 44, 9, p. 733-736 4 p.

Research output: Contribution to journalShort survey

1 Citation (Scopus)

Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)

Zhao, D., Zhang, F., Wang, B., Liu, B., Li, L., Kim, S. Y., Goodman, S. B., Hernigou, P., Cui, Q., Lineaweaver, W. C., Xu, J., Drescher, W. R. & Qin, L., Mar 2020, In : Journal of Orthopaedic Translation. 21, p. 100-110 11 p.

Research output: Contribution to journalShort survey

Open Access
4 Citations (Scopus)
Review article

Advanced Genetic Approaches in Discovery and Characterization of Genes Involved With Osteoporosis in Mouse and Human

Yuan, J., Tickner, J., Mullin, B. H., Zhao, J., Zeng, Z., Morahan, G. & Xu, J., 2 Apr 2019, In : Frontiers in Genetics. 10, 13 p., 288.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Angiogenic factors in bone local environment

Chim, S., Tickner, J., Chow, S. T., Kuek, V., Guo, B., Zhang, G., Rosen, V., Erber, W. & Xu, J., 2013, In : Cytokine and Growth Factor Reviews. 24, 3, p. 297-310

Research output: Contribution to journalReview article

128 Citations (Scopus)

Bioreactor Design for Tendon/Ligament Engineering

Wang, T., Gardiner, B., Lin, Z., Rubenson, J., Kirk, T. B., Wang, A., Xu, J., Smith, D., Lloyd, D. & Zheng, M., 2013, In : Tissue Engineering Part B: Reviews. 19, 2, p. 1-14

Research output: Contribution to journalReview article

44 Citations (Scopus)

Chondromodulin-1 in health, osteoarthritis, cancer, and heart disease

Zhu, S., Qiu, H., Bennett, S., Kuek, V., Rosen, V., Xu, H. & Xu, J., Nov 2019, In : Cellular and Molecular Life Sciences. 76, 22, p. 4493-4502

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Current research on pharmacologic and regenerative therapies for osteoarthritis

Zhang, W., Ouyang, H., Dass, C. R. & Xu, J., 1 Mar 2016, In : Bone Research. 4, p. 1-14 14 p., 15040 .

Research output: Contribution to journalReview article

Open Access
140 Citations (Scopus)

EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis

Hong, G., Kuek, V., Shi, J., Zhou, L., Han, X., He, W., Tickner, J., Qiu, H., Wei, Q. & Xu, J., 1 Nov 2018, In : Journal of Cellular Physiology. 233, 11, p. 8526-8537 12 p.

Research output: Contribution to journalReview article

Open Access
File
10 Citations (Scopus)
250 Downloads (Pure)

Emerging Trend in the Pharmacotherapy of Osteoarthritis

Zhang, W., Robertson, W. B., Zhao, J., Chen, W. & Xu, J., 2 Jul 2019, In : Frontiers in Endocrinology. 10, 9 p., 431.

Research output: Contribution to journalReview article

Open Access
10 Citations (Scopus)

Endothelial cells produce angiocrine factors to regulate bone and cartilage via versatile mechanisms

Zhu, S., Bennett, S., Kuek, V., Xiang, C., Xu, H., Rosen, V. & Xu, J., 1 May 2020, In : Theranostics. 10, 13, p. 5957-5965 9 p.

Research output: Contribution to journalReview article

Open Access

Introduction: Understanding the signalling mechanisms in molecular physiology and diseases

Liu, J-P. & Xu, J., 1 Aug 2012, In : Clinical and Experimental Pharmacology and Physiology. 39, 8, p. 658-660

Research output: Contribution to journalReview article

Massage alleviates delayed onset muscle soreness after strenuous exercise: A systematic review and meta-analysis

Guo, J., Li, L., Gong, Y., Zhu, R., Xu, J., Zou, J. & Chen, X., 27 Sep 2017, In : Frontiers in Physiology. 8, 747.

Research output: Contribution to journalReview article

Open Access
10 Citations (Scopus)

MicroRNAs as Potential Targets for Treatment of Osteoclast-Related Diseases

Li, H., Zhai, Z., Qu, X., Xu, J., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 422-431 10 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

MiR-214 is an important regulator of the musculoskeletal metabolism and disease

Sun, Y., Kuek, V., Liu, Y., Tickner, J., Yuan, Y., Chen, L., Zeng, Z., Shao, M., He, W. & Xu, J., Jan 2019, In : Journal of Cellular Physiology. 234, 1, p. 231-245 15 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

Molecular structure, expression, and functional role of Clec11a in skeletal biology and cancers

Wang, M., Guo, J., Zhang, L., Kuek, V., Xu, J. & Zou, J., 1 Oct 2020, In : Journal of Cellular Physiology. 235, 10, p. 6357-6365 9 p.

Research output: Contribution to journalReview article

Molecular structure and differential function of choline kinases CHKα and CHKβ in musculoskeletal system and cancer

Chen, X., Qiu, H., Wang, C., Yuan, Y., Tickner, J., Xu, J. & Zou, J., Feb 2017, In : Cytokine and Growth Factor Reviews. 33, p. 65-72 8 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
287 Downloads (Pure)

Molecular structure and the role of high-temperature requirement protein 1 in skeletal disorders and cancers

Li, Y., Yuan, J., Rothzerg, E., Wu, X., Xu, H., Zhu, S. & Xu, J., 22 Dec 2019, In : Cell Proliferation. e12746.

Research output: Contribution to journalReview article

Open Access

Pathological mechanisms and therapeutic outlooks for arthrofibrosis

Usher, K. M., Zhu, S., Mavropalias, G., Carrino, J. A., Zhao, J. & Xu, J., 1 Dec 2019, In : Bone Research. 7, 1, 9.

Research output: Contribution to journalReview article

Open Access
7 Citations (Scopus)

Protein Cytl1: its role in chondrogenesis, cartilage homeostasis, and disease

Zhu, S., Kuek, V., Bennett, S., Xu, H., Rosen, V. & Xu, J., 14 May 2019, In : Cellular and Molecular Life Sciences. 76, 18, p. 3515-3523

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

Rheumatoid arthritis: Pathological mechanisms and modern pharmacologic therapies

Guo, Q., Wang, Y., Xu, D., Nossent, J., Pavlos, N. J. & Xu, J., 1 Dec 2018, In : Bone Research. 6, 1, 16.

Research output: Contribution to journalReview article

Open Access
126 Citations (Scopus)

Roles of neurotrophins in skeletal tissue formation and healing

Su, Y. W., Zhou, X. F., Foster, B. K., Grills, B. L., Xu, J. & Xian, C. J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 2133-2145 13 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis

Tong, X., Chen, X., Zhang, S., Huang, M., Shen, X., Xu, J. & Zou, J., 2019, In : BioMed Research International. 2019, 8 p., 8171897.

Research output: Contribution to journalReview article

Open Access
2 Citations (Scopus)

The emerging role of Hippo signaling pathway in regulating osteoclast formation

Yang, W., Han, W., Qin, A., Wang, Z., Xu, J. & Qian, Y., 1 Jun 2018, In : Journal of Cellular Physiology. 233, 6, p. 4606-4617 12 p.

Research output: Contribution to journalReview article

15 Citations (Scopus)

The emerging role of NPNT in tissue injury repair and bone homeostasis

Sun, Y., Kuek, V., Qiu, H., Tickner, J., Chen, L., Wang, H., He, W. & Xu, J., 1 Mar 2018, In : Journal of Cellular Physiology. 233, 3, p. 1887-1894 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

The emerging roles of hnRNPK

Wang, Z., Qiu, H., He, J., Liu, L., Xue, W., Fox, A., Tickner, J. & Xu, J., 19 Sep 2019, In : Journal of Cellular Physiology.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Therapeutic potential and outlook of alternative medicine for osteoporosis

Wang, T., Liu, Q., Tjhioe, W., Zhao, J., Lu, A., Zhang, G., Tan, R. X., Zhou, M., Xu, J. & Feng, H. T., 1 Jul 2017, In : Current Drug Targets. 18, 9, p. 1051-1068 18 p.

Research output: Contribution to journalReview article

24 Citations (Scopus)

The role of glial cell line-derived neurotrophic factor family member artemin in neurological disorders and cancers

Zhu, S., Li, Y., Bennett, S., Chen, J., Weng, I. Z., Huang, L., Xu, H. & Xu, J., 1 Jul 2020, In : Cell Proliferation. 53, 7, e12860.

Research output: Contribution to journalReview article

Open Access

Zoledronic Acid: Pleiotropic Anti-tumor Mechanism and Therapeutic Outlook for Osteosarcoma

Ouyang, Z., Li, H., Zhai, Z., Xu, J., Dass, C. R., Qin, A. & Dai, K., 2018, In : Current Drug Targets. 19, 5, p. 409-421 13 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)
Literature review

The role of SATB2 in skeletogenesis and human disease

Zhao, X., Qu, Z., Tickner, J., Xu, J., Dai, K. & Zhang, X., 2014, In : Cytokine and Growth Factor Reviews. 25, p. 35–44

Research output: Contribution to journalLiterature review

43 Citations (Scopus)
Letter

International Combined Orthopaedic Research Societies: A model for international collaboration to promote orthopaedic and musculoskeletal research

Miclau, T., Adachi, N., Antoniou, J., Baldini, N., Blunn, G., Boyd, S., Chang, JK., Grimm, B., Guo, X. E., Im, GI., Kim, SY., Korkusuz, F., Lee, OKS., Mccaskie, A., Richards, R. G., Shetty, G., Sivananthan, S., Tang, T., Xu, J. & Qin, L., 2014, In : Journal of Orthopaedic Translation. Online, p. 1-6

Research output: Contribution to journalLetter

Open Access
10 Citations (Scopus)
Conference paper

TAK1 inhibition for the prevention of inflammation-induced preterm birth

Ireland, D., Pugazhenthi, K., Xu, J. & Keelan, J., 2014, Annual Meeting of the Society for Gynecologic Investigation, Reprod Sci. United States: SAGE Publications Ltd, Vol. 21. p. 238A

Research output: Chapter in Book/Conference paperConference paper

Article

A005, a novel inhibitor of phosphatidylinositol 3-kinase/mammalian target of rapamycin, prevents osteosarcoma-induced osteolysis

Lian, Z., Han, J., Huang, L., Wei, C., Fan, Y., Xu, J., Zhou, M., Feng, H., Liu, Q., Chen, L., Li, Z., Cheng, H., Yuan, G., Lin, X., Song, F., Su, Y., Wang, C., Huang, G., Qin, A., Song, Y. & 1 others, Yao, G., 1 Jan 2019, In : Carcinogenesis. 40, 2, p. E1-E13

Research output: Contribution to journalArticle

2 Citations (Scopus)

Achyranthes bidentata polysaccharide suppresses osteoclastogenesis and bone resorption via inhibiting RANKL signaling

Song, D., Cao, Z., Huang, S., Tickner, J., Li, N., Qiu, H., Chen, X., Wang, C., Chen, K., Sun, Y., Dong, S. & Xu, J., 1 Jun 2018, In : Journal of Cellular Biochemistry. 119, 6, p. 4826-4835 10 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
330 Downloads (Pure)

A conceptual framework for computational models of Achilles tendon homeostasis

Smith, D., Rubenson, J., Lloyd, D., Zheng, M., Fernandez, J., Besier, T., Xu, J. & Gardiner, B., 2013, In : Wiley Interdisciplinary Reviews-Systems Biology and Medicine. 5, 5, p. 523-538

Research output: Contribution to journalArticle

21 Citations (Scopus)

A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation of microRNAs in osteoclasts

Liu, J., Dang, L., Li, D., Liang, C., He, X., Wu, H., Qian, A., Yang, Z., Au, D. W. T., Chiang, M. W. L., Zhang, B. T., Han, Q., Yue, K. K. M., Zhang, H., Lv, C., Pan, X., Xu, J., Bian, Z., Shang, P., Tan, W. & 4 others, Liang, Z., Guo, B., Lu, A. & Zhang, G., 2015, In : Biomaterials. 52, 1, p. 148-160

Research output: Contribution to journalArticle

39 Citations (Scopus)

Amyloid β peptide enhances RANKL-induced osteoclast activation through NF-κB, ERK, and calcium oscillation signaling

Li, S., Yang, B., Teguh, D., Zhou, L., Xu, J. & Rong, L., 1 Oct 2016, In : International Journal of Molecular Sciences. 17, 10, 1683.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Analysis of circulating microRNAs aberrantly expressed in alcohol-induced osteonecrosis of femoral head

Hong, G., Han, X., He, W., Xu, J., Sun, P., Shen, Y., Wei, Q. & Chen, Z., 1 Dec 2019, In : Scientific Reports. 9, 1, 18926.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Andrographolide inhibits ovariectomy-induced bone loss via the suppression of RANKL signaling pathways

Wang, T., Liu, Q., Zhou, L., Yuan, J., Lin, X., Zeng, R., Liang, X., Zhao, J. & Xu, J., 17 Nov 2015, In : International Journal of Molecular Sciences. 16, 11, p. 27470-27481 12 p.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

An overview of the regulation of bone remodelling at the cellular level

Kular, J., Tickner, J., Chim, S. & Xu, J., 2012, In : Clinical Biochemistry. 45, p. 863-873

Research output: Contribution to journalArticle

206 Citations (Scopus)

Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis

Duan, W., Wang, Q., Li, F., Xiang, C., Zhou, L., Xu, J., Feng, H. & Wei, X., 2014, In : Chinese Medical Journal. 127, p. 3932-3936

Research output: Contribution to journalArticle

2 Citations (Scopus)

A polyamidoamne dendrimer functionalized graphene oxide for DOX and MMP-9 shRNA plasmid co-delivery

Gu, Y., Guo, Y., Wang, C., Xu, J., Wu, J., Kirk, T. B., Ma, D. & Xue, W., 1 Jan 2017, In : Materials Science and Engineering C. 70, p. 572-585 14 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Aptamer-functionalized lipid nanoparticles targeting osteoblasts as a novel RNA interference-based bone anabolic strategy

Liang, C., Guo, B., Wu, H., Shao, N., Li, D., Liu, J., Dang, L., Wang, C., Li, H., Li, S., Lau, W. K., Cao, Y., Yang, Z., Lu, C., He, X., Au, D. W. T., Pan, X., Zhang, B. T., Zhang, H., Yue, K. & 11 others, Qian, A., Shang, P., Xu, J., Xiao, L., Bian, Z., Tan, W., Liang, Z., He, F., Zhang, L., Lu, A. & Zhang, G., 2015, In : Nature Medicine. 21, 3, p. 288-296

Research output: Contribution to journalArticle

134 Citations (Scopus)

Arctiin abrogates osteoclastogenesis and bone resorption via suppressing RANKL-induced ROS and NFATc1 activation

Chen, D., Ye, Z., Wang, C., Wang, Q., Wang, H., Kuek, V., Wang, Z., Qiu, H., Yuan, J., Kenny, J., Yang, F., He, J., Liu, Y., Wang, G., Zhang, M., Zhang, G., Wang, J., Chen, P. & Xu, J., Sep 2020, In : Pharmacological Research. 159, 104944.

Research output: Contribution to journalArticle

Artesunate inhibits RANKL-induced osteoclastogenesis and bone resorption in vitro and prevents LPS-induced bone loss in vivo

Wei, C. M., Liu, Q., Song, F. M., Lin, X. X., Su, Y. J., Xu, J., Huang, L., Zong, S. H. & Zhao, J. M., 1 Jan 2018, In : Journal of Cellular Physiology. 233, 1, p. 476-485 10 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Artesunate suppresses RANKL-induced osteoclastogenesis through inhibition of PLCγ1-Ca2+–NFATc1 signaling pathway and prevents ovariectomy-induced bone loss

Zeng, X., Zhang, Y., Wang, S., Wang, K., Tao, L., Zou, M., Chen, N., Xu, J., Liu, S. & Li, X., 15 Jan 2017, In : Biochemical Pharmacology. 124, p. 57-68 12 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways

Hong, G., Zhou, L., Han, X., Sun, P., Chen, Z., He, W., Tickner, J., Chen, L., Shi, X. & Xu, J., 27 Mar 2020, In : Frontiers in Pharmacology. 11, 331.

Research output: Contribution to journalArticle

Open Access

Asiaticoside, a component of Centella asiatica attenuates RANKL-induced osteoclastogenesis via NFATc1 and NF-kappa B signaling pathways

He, L., Hong, G., Zhou, L., Zhang, J., Fang, J., He, W., Tickner, J., Han, X., Zhao, L. & Xu, J., Apr 2019, In : Journal of Cellular Physiology. 234, 4, p. 4267-4276 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Asperpyrone A attenuates RANKL-induced osteoclast formation through inhibiting NFATc1, Ca2+ signalling and oxidative stress

Chen, X., Wang, C., Qiu, H., Yuan, Y., Chen, K., Cao, Z., Xiang Tan, R., Tickner, J., Xu, J. & Zou, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8269-8279 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis

Jin, H., Wang, Q., Chen, K., Xu, K., Pan, H., Chu, F., Ye, Z., Wang, Z., Tickner, J., Qiu, H., Wang, C., Kenny, J., Xu, H., Wang, T. & Xu, J., 1 Dec 2019, In : Journal of Cellular and Molecular Medicine. 23, 12, p. 8355-8368 14 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)