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  • 2018
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  • 2010

Author

  • Markus Schlaich
Article

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

Esler, M. D., Krum, H., Sobotka, P. A., Schlaich, M. P., Schmieder, R. E., Böhm, M., Mahfoud, F., Sievert, H., Wunderlich, N., Rump, L. C., Vonend, O., Uder, M., Lobo, M., Caulfield, M., Erglis, A., Azizi, M., Sapoval, M., Thambar, S., Persu, A., Renkin, J. & 24 others, Schunkert, H., Weil, J., Hoppe, U. C., Walton, T., Scheinert, D., Binder, T., Januszewicz, A., Witkowski, A., Ruilope, L. M., Whitbourn, R., Bruck, H., Downes, M., Lüscher, T. F., Jardine, A. G., Webster, M. W., Zeller, T., Sadowski, J., Bartus, K., Straley, C. A., Barman, N. C., Lee, D. P., Witteles, R. M., Bhalla, V. & Massaro, J. M., 4 Dec 2010, In : The Lancet. 376, 9756, p. 1903-1909 7 p.

Research output: Contribution to journalArticle

1689 Citations (Scopus)

Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial

Stoiber, L., Mahfoud, F., Zamani, S. M., Lapinskas, T., Böhm, M., Ewen, S., Kulenthiran, S., Schlaich, M. P., Esler, M. D., Hammer, T., Stensæth, K. H., Pieske, B., Dreysse, S., Fleck, E., Kühne, T., Kelm, M., Stawowy, P. & Kelle, S., 1 Aug 2018, In : Clinical Research in Cardiology. 107, 8, p. 642-652 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2 Citations (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2

Matthews, V. B., Elliot, R. H., Rudnicka, C., Hricova, J., Herat, L. & Schlaich, M. P., 1 Oct 2017, In : Journal of Hypertension. 35, 10, p. 2059–2068

Research output: Contribution to journalArticle

45 Citations (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Booth, L. C., Schlaich, M. P., Nishi, E. E., Yao, S. T., Xu, J., Ramchandra, R., Lambert, G. W. & May, C. N., 1 Jul 2015, In : International Journal of Cardiology. 190, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
75 Downloads (Pure)

Soluble vascular endothelial growth factor receptor-1 is reduced in patients with resistant hypertension after renal denervation

Eikelis, N., Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Sata, Y., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : Journal of Human Hypertension. 31, 4, p. 248-252 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
249 Citations (Scopus)

Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Krum, H., Narkiewicz, K., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 2014, In : Hypertension. 64, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Sympathetic activation and endothelial dysfunction in polycystic ovary syndrome are not explained by either obesity or insulin resistance

Lambert, E. A., Teede, H., Sari, C. I., Jona, E., Shorakae, S., Woodington, K., Hemmes, R., Eikelis, N., Straznicky, N. E., De Courten, B., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Dec 2015, In : Clinical Endocrinology. 83, 6, p. 812-819 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Sympathetic and vascular dysfunction in adult patients with Fontan circulation

Lambert, E., D'Udekem, Y., Cheung, M., Sari, C. I., Inman, J., Ahimastos, A., Eikelis, N., Pathak, A., King, I., Grigg, L., Schlaich, M. & Lambert, G., 20 Aug 2013, In : International Journal of Cardiology. 167, 4, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

27 Citations (Scopus)

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
140 Citations (Scopus)

Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects

Straznicky, N. E., Lambert, E. A., Nestel, P. J., McGrane, M. T., Dawood, T., Schlaich, M. P., Masuo, K., Eikelis, N., De Courten, B., Mariani, J. A., Esler, M. D., Socratous, F., Chopra, R., Sari, C. I., Paul, E. & Lambert, G. W., 2010, In : Diabetes. 59, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

Open Access
70 Citations (Scopus)

Sympathetic Response and Outcomes Following Renal Denervation in Patients With Chronic Heart Failure: 12-Month Outcomes From the Symplicity HF Feasibility Study

Hopper, I., Gronda, E., Hoppe, U. C., Rundqvist, B., Marwick, T. H., Shetty, S., Hayward, C., Lambert, T., Hering, D., Esler, M., Schlaich, M., Walton, A., Airoldi, F., Brandt, M. C., Cohen, S. A., Reiters, P. & Krum, H., 1 Sep 2017, In : Journal of Cardiac Failure. 23, 9, p. 702-707 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The effect of renal denervation on plasma adipokine profile in patients with treatment resistant hypertension

Eikelis, N., Hering, D., Marusic, P., Duval, J., Hammond, L. J., Walton, A. S., Lambert, E. A., Esler, M. D., Lambert, G. W. & Schlaich, M. P., 30 May 2017, In : Frontiers in Physiology. 8, MAY, 369.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The metalloproteinase ADAM28 promotes metabolic dysfunction in mice

Herat, L., Rudnicka, C., Okada, Y., Mochizuki, S., Schlaich, M. & Matthews, V., 21 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 12 p., 884.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Karapanagiotidis, S., Wong, C., Eikelis, N., Richards, K. L., Lee, G., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P. & Lambert, E. A., 1 Feb 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 2

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
Open Access
File
6 Citations (Scopus)
440 Downloads (Pure)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

5 Citations (Scopus)
Abstract/Meeting Abstract

Transvenous carotid body ablation for resistant hypertension: main results of a multicentre safety and proof-of-principle cohort study

Schlaich, M., Schultz, C., Shetty, S., Hering, D., Worthley, S., Delacroix, S., Reddy, V., Sievert, H., Zeller, T., Noory, E., Boehm, M., Mahfoud, F., Malek, F., Kmonicek, P. & Neuzil, P., Aug 2018, In : European Heart Journal. 39, p. 267-267 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract