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Author

  • Markus Schlaich
Article

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Lambert, E. A., Sari, C. I., Eikelis, N., Nestel, P. J., Phillips, S. E., Hering, D., Karapanagiotidis, S., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Apr 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 4, p. 1544-1550 7 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Association between the sympathetic firing pattern and anxiety level in patients with the metabolic syndrome and elevated blood pressure

Lambert, E., Dawood, T., Straznicky, N., Sari, C., Schlaich, M., Esler, M. & Lambert, G., Mar 2010, In : Journal of Hypertension. 28, 3, p. 543-550 8 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)

Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., Hilgers, K. F. & Schmieder, R. E., Jun 2011, In : Pharmacogenetics and Genomics. 21, 6, p. 347-349 3 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Blood pressure screening during the May Measurement Month 2017 programme in Vietnam-South-East Asia and Australasia

Van Minh, H., Viet, N. L., Sinh, C. T., Hung, P. N., Mong Ngoc, N. T., Hung, N. V., Son, T. K., Đong, N. T., Thang, Đ. C., Tien, H. A., Tuan, H. C., Beaney, T., Xia, X., Poulter, N. R. & Schlaich, M. P., Apr 2019, In : European Heart Journal Supplements. 21, Suppl D, p. D127-D129

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-based renal denervation in normotensive sheep

McArdle, Z., Pontes, R. B., Yao, S. T., Lankadeva, Y. R., Singh, R. R., Hood, S. G., Schlaich, M. P., May, C. N. & Booth, L. C., 1 Aug 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 317, 2, p. R319-R327

Research output: Contribution to journalArticle

1 Citation (Scopus)

Catheter-based renal denervation: the next chapter begins

Mahfoud, F., Schlaich, M., Böhm, M., Esler, M. & Lüscher, T. F., 14 Dec 2018, In : European Heart Journal. 39, 47, p. 4144-4149 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage

Singh, R. R., Sajeesh, V., Booth, L. C., McArdle, Z., May, C. N., Head, G. A., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 28 Feb 2017, In : Journal of the American College of Cardiology. 69, 8, p. 951-964 14 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months

Symplicity HTN-1 Investigators & Schlaich, M., May 2011, In : Hypertension. 57, 5, p. 911-7 7 p.

Research output: Contribution to journalArticle

698 Citations (Scopus)

Change in sympathetic nerve firing pattern associated with dietary weight loss in the metabolic syndrome

Lambert, E., Straznicky, N. E., Dawood, T., Ika-Sari, C., Grima, M., Esler, M. D., Schlaich, M. P. & Lambert, G. W., Dec 2011, In : Frontiers in Physiology. 2, 52.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Comparison of commonly used questionnaires to identify obstructive sleep apnea in a high-risk population

Kee, K., Dixon, J., Shaw, J., Vulikh, E., Schlaich, M., Kaye, D. M., Zimmet, P. & Naughton, M. T., 15 Dec 2018, In : Journal of clinical sleep medicine. 14, 12, p. 2057-2064 8 p.

Research output: Contribution to journalArticle

Device-based antihypertensive therapy: Therapeutic modulation of the autonomic nervous system

Krum, H., Sobotka, P., Mahfoud, F., Böhm, M., Esler, M. & Schlaich, M., 18 Jan 2011, In : Circulation. 123, 2, p. 209-215 7 p.

Research output: Contribution to journalArticle

Open Access
126 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Effect of pupil dilation with tropicamide on retinal vascular caliber

Frost, S., Gregory, C., Robinson, L., Yu, S., Xiao, D., Mehdizadeh, M., Burnham, S., Dehghani, C., Vignarajan, J., Kanagasingam, Y., Schlaich, M. P. & Prentice, D., 3 Jul 2019, In : Ophthalmic Epidemiology. 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effect of renal denervation on kidney function in patients with chronic kidney disease

Hering, D., Marusic, P., Duval, J., Sata, Y., Head, G. A., Denton, K. M., Burrows, S., Walton, A. S., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 93-97 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
96 Citations (Scopus)

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 10 May 2011, In : Circulation. 123, 18, p. 1940-1946 7 p.

Research output: Contribution to journalArticle

Open Access
465 Citations (Scopus)

Effects of Moxonidine and Low-Calorie Diet: Cardiometabolic Benefits from Combination of Both Therapies

Lambert, E. A., Sari, C. I., Eikelis, N., Phillips, S. E., Grima, M., Straznicky, N. E., Dixon, J. B., Esler, M., Schlaich, M. P., Head, G. A. & Lambert, G. W., 1 Nov 2017, In : Obesity. 25, 11, p. 1894-1902 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry

Mahfoud, F., Böhm, M., Schmieder, R., Narkiewicz, K., Ewen, S., Ruilope, L., Schlaich, M., Williams, B., Fahy, M. & Mancia, G., 1 Nov 2019, In : European Heart Journal. 40, 42, p. 3474-3482 9 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Effects of renal sympathetic denervation on urinary sodium excretion in patients with resistant hypertension

Pöss, J., Ewen, S., Schmieder, R. E., Muhler, S., Vonend, O., Ott, C., Linz, D., Geisel, J., Rump, L. C., Schlaich, M., Böhm, M. & Mahfoud, F., 29 Aug 2015, In : Clinical Research in Cardiology. 104, 8, p. 672-678 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Endothelial function in healthy young individuals is associated with dietary consumption of saturated fat

Lambert, E. A., Phillips, S., Belski, R., Tursunalieva, A., Eikelis, N., Sari, C. I., Dixon, J. B., Straznicky, N., Grima, M., Head, G. A., Schlaich, M. & Lambert, G. W., 9 Nov 2017, In : Frontiers in Physiology. 8, November, 876.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals

Straznicky, N. E., Grima, M. T., Lambert, E. A., Eikelis, N., Dawood, T., Lambert, G. W., Nestel, P. J., Masuo, K., Sari, C. I., Chopra, R., Mariani, J. A. & Schlaich, M. P., 1 Mar 2011, In : Journal of Hypertension. 29, 3, p. 553-564 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

123 Citations (Scopus)

Folic acid treatment normalizes nos-dependence of vascular tone in the metabolic syndrome

Schneider, M. P., Schlaich, M. P., Harazny, J. M., Raff, U., Ritt, M., Ott, C. & Schmieder, R. E., May 2011, In : Obesity. 19, 5, p. 960-967 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men

Lambert, E., Lambert, G., Ika-Sari, C., Dawood, T., Lee, K., Chopra, R., Straznicky, N., Eikelis, N., Drew, S., Tilbrook, A., Dixon, J., Esler, M. & Schlaich, M. P., 1 Jul 2011, In : Hypertension. 58, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Health-related quality of life and blood pressure 12months after renal denervation

Lambert, G. W., Hering, D., Marusic, P., Thorp, A., Sata, Y., Lee, R., Duval, J., Hammond, L., Head, G. A., Esler, M. D., Lambert, E. A., Dixon, J. B., Dhar, A. K., Barton, D. A. & Schlaich, M., Nov 2015, In : Journal of Hypertension. 33, 11, p. 2350-2358 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Home blood pressuremonitoring: Australian Expert Consensus Statement

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2015, In : Journal of Hypertension. 33, 9, p. 1721-1728

Research output: Contribution to journalArticle

45 Citations (Scopus)

Inverse association between sympathetic nervous system activity and bone mass in middle aged overweight individuals

Lambert, E., Phillips, S., Tursunalieva, A., Eikelis, N., Sari, C., Dixon, J., Straznicky, N., Grima, M., Schlaich, M. & Lambert, G., Jun 2018, In : Bone. 111, p. 123-128 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

May measurement month 2017: An analysis of the blood pressure screening campaign results in Indonesia-south-east Asia and australAsia

Widyantoro, B., Situmorang, T. D., Turana, Y., Barack, R., Delliana, J., Roesli, R. M. A., Erwinanto, E., Hermiawaty, E., Kuncoro, A. S., Sofiatin, Y., Beaney, T., Xia, X., Poulter, N. R., Schlaich, M. P. & Santoso, A., 2019, In : European Heart Journal, Supplement. 21, p. D63-D65

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

May Measurement Month 2017: an analysis of blood pressure screening results worldwide

MMM Investigators, 1 Jul 2018, In : The Lancet Global Health. 6, 7, p. e736-e743

Research output: Contribution to journalArticle

Open Access
94 Citations (Scopus)

May Measurement Month 2017: an analysis of blood pressure screening results from Australia-South-East Asia and Australasia

Carnagarin, R., Fonseca, R., Brockman, D., Hering, D., Matthews, V., Mihailidou, A., Reid, C., Lee, R., Lambert, G. W., Burrell, L. M., Sharman, J. E., Xia, X., Poulter, N. R., Beaney, T., Islam, S. M. S., Carrington, M. & Schlaich, M., 24 Apr 2019, In : European Heart Journal Supplements. 21, Suppl. D, p. D14-D16

Research output: Contribution to journalArticle

Open Access

May measurement month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

MMM Investigators, 1 Jul 2019, In : European Heart Journal. 40, 25, p. 2006-2017 12 p.

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Multivariable Analysis of Patients With Severe Persistent Postprocedural Hypotension After Carotid Artery Stenting

Oshin, O., Varcoe, R., Wong, J., Burrows, S., Altaf, N., Schlaich, M., Weerasooriya, R., Gray, W., Deloose, K., Baumgartner, I. & Mwipatayi, B. P., 21 Aug 2019, In : Journal of Endovascular Therapy.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Muscle sympathetic nerve activity is associated with elements of the plasma lipidomic profile in young asian adults

Eikelis, N., Lambert, E. A., Phillips, S., Sari, C. I., Mundra, P. A., Weir, J. M., Huynh, K., Grima, M. T., Straznicky, N. E., Dixon, J. B., Schlaich, M. P., Meikle, P. J. & Lambert, G. W., 1 Jun 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 6, p. 2059-2068 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Neck circumference is associated with muscle sympathetic nerve activity in overweight and obese men but not women

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P., Phillips, S. E. & Lambert, E. A., 6 Apr 2017, In : Frontiers in Physiology. 8, APR, 203.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
230 Downloads (Pure)

New developments in the pathogenesis of obesity-induced hypertension

Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. & Jordan, J., 2015, In : Journal of Hypertension. 33, 8, p. 1499-1508

Research output: Contribution to journalArticle

50 Citations (Scopus)

Opposing effects of shear-mediated dilation and myogenic constriction on artery diameter in response to handgrip exercise in humans

Atkinson, C., Carter, H., Naylor, L., Dawson, E. A., Marusic, P., Hering, D., Schlaich, M., Thijssen, D. H. J. & Green, D. J., 15 Oct 2015, In : Journal of Applied Physiology. 119, 8, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
366 Downloads (Pure)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

430 Citations (Scopus)

Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Richards, K., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Jul 2015, In : Metabolism: clinical and experimental. 64, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

Esler, M., Lambert, E. & Schlaich, M., Dec 2010, In : Journal of Applied Physiology. 109, 6, p. 1996-1998 3 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Recurrent postural vasovagal syncope: Sympathetic nervous system phenotypes

Vaddadi, G., Guo, L., Esler, M., Socratous, F., Schlaich, M., Chopra, R., Eikelis, N., Lambert, G., Trauer, T. & Lambert, E., Oct 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Reduction in basal nitric oxide activity causes albuminuria

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. & Schmieder, R. E., Feb 2011, In : Diabetes. 60, 2, p. 572-576 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss

Straznicky, N. E., Grima, M. T., Sari, C. I., Lambert, E. A., Phillips, S. E., Eikelis, N., Kobayashi, D., Hering, D., Mariani, J. A., Dixon, J. B., Nestel, P. J., Karapanagiotidis, S., Schlaich, M. P. & Lambert, G. W., 22 Aug 2015, In : Cardiovascular Diabetology. 14, 1, 113.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Reinnervation following catheter-based radio-frequency renal denervation

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 20 Apr 2015, In : Experimental Physiology. 100, 5, p. 485-490 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)