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  • 2017
  • 2016
  • 2014
  • 2013

Author

  • Markus Schlaich
Article

ADAM19: A novel target for metabolic syndrome in humans and mice

Weerasekera, L., Rudnicka, C., Sang, Q. X., Curran, J. E., Johnson, M. P., Moses, E. K., Göring, H. H. H., Blangero, J., Hricova, J., Schlaich, M. & Matthews, V. B., 7 Feb 2017, In : Mediators of Inflammation. 2017, 9 p., 7281986.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 9 Jul 2013, In : Circulation. 128, 2, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
217 Citations (Scopus)

Anatomical and procedural determinants of catheter-based renal denervation

Ewen, S., Ukena, C., Lüscher, T. F., Bergmann, M., Blankestijn, P. J., Blessing, E., Cremers, B., Dörr, O., Hering, D., Kaiser, L., Nef, H., Noory, E., Schlaich, M., Sharif, F., Sudano, I., Vogel, B., Voskuil, M., Zeller, T., Tzafriri, A. R., Edelman, E. R. & 4 others, Lauder, L., Scheller, B., Böhm, M. & Mahfoud, F., 1 Oct 2016, In : Cardiovascular Revascularization Medicine. 17, 7, p. 474-479 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism

Marques, F. Z., Eikelis, N., Bayles, R. G., Lambert, E. A., Straznicky, N. E., Hering, D., Esler, M. D., Head, G. A., Barton, D. A., Schlaich, M. P. & Lambert, G. W., 1 Jan 2017, In : Molecular Psychiatry. 22, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage

Singh, R. R., Sajeesh, V., Booth, L. C., McArdle, Z., May, C. N., Head, G. A., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 28 Feb 2017, In : Journal of the American College of Cardiology. 69, 8, p. 951-964 14 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study

Malan, L., Hamer, M., Von Känel, R., Schlaich, M., Reimann, M., Frasure-Smith, N., Lambert, G. W., Vilser, W., Harvey, B. H., Steyn, F. & Malan, N. T., 2016, In : Nitric Oxide - Biology and Chemistry. 55-56, p. 10-17

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Chronic kidney disease: Role of sympathetic nervous system activation and potential benefits of renal denervation

Hering, D., Esler, M. D. & Schlaich, M. P., 2013, In : EuroIntervention. 9, p. R127-R135

Research output: Contribution to journalArticle

26 Citations (Scopus)

Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Reimann, M., Steyn, H. S., Schutte, R., Smith, W., Van Rooyen, J. M., Fourie, C. M. T. & Malan, N. T., 30 Sep 2013, In : International Journal of Cardiology. 168, 2, p. 999-1005 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Defensive coping facilitates higher blood pressure and early sub-clinical structural vascular disease via alterations in heart rate variability: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G., Ziemssen, T., Reimann, M., Frasure-Smith, N., Amirkhan, J. H., Schutte, R., van Rooyen, J. M., Mels, C. M., Fourie, C. M. T., Uys, A. S. & Malan, N. T., 1 Apr 2013, In : Atherosclerosis. 227, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: A double-blind, randomized, crossover trial

De Courten, B., De Courten, M. P. J., Soldatos, G., Dougherty, S. L., Straznicky, N., Schlaich, M., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., Cooper, M. E., Schalkwijk, C. G., Walker, K. Z. & Forbes, J. M., 1 Jun 2016, In : American Journal of Clinical Nutrition. 103, 6, p. 1426-1433 8 p.

Research output: Contribution to journalArticle

Open Access
56 Citations (Scopus)

Dyslipidemia is associated with sympathetic nervous activation and impaired endothelial function in young females

Lambert, E., Straznicky, N., Sari, C. I., Eikelis, N., Hering, D., Head, G., Dixon, J., Esler, M., Schlaich, M. & Lambert, G., 1 Feb 2013, In : American Journal of Hypertension. 26, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)

Effect of renal denervation on kidney function in patients with chronic kidney disease

Hering, D., Marusic, P., Duval, J., Sata, Y., Head, G. A., Denton, K. M., Burrows, S., Walton, A. S., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 93-97 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
96 Citations (Scopus)

Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: The sympathetic activity and ambulatory blood pressure in Africans study

Reimann, M., Hamer, M., Malan, N. T., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Boeger, R. H. & Malan, L., 2013, In : Psychosomatic Medicine. 75, 8, p. 751-758 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of Moxonidine and Low-Calorie Diet: Cardiometabolic Benefits from Combination of Both Therapies

Lambert, E. A., Sari, C. I., Eikelis, N., Phillips, S. E., Grima, M., Straznicky, N. E., Dixon, J. B., Esler, M., Schlaich, M. P., Head, G. A. & Lambert, G. W., 1 Nov 2017, In : Obesity. 25, 11, p. 1894-1902 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Endothelial function in healthy young individuals is associated with dietary consumption of saturated fat

Lambert, E. A., Phillips, S., Belski, R., Tursunalieva, A., Eikelis, N., Sari, C. I., Dixon, J. B., Straznicky, N., Grima, M., Head, G. A., Schlaich, M. & Lambert, G. W., 9 Nov 2017, In : Frontiers in Physiology. 8, November, 876.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Feasibility of catheter-based renal nerve ablation and effects on sympathetic nerve activity and blood pressure in patients with end-stage renal disease

Schlaich, M. P., Bart, B., Hering, D., Walton, A., Marusic, P., Mahfoud, F., Böhm, M., Lambert, E. A., Krum, H., Sobotka, P. A., Schmieder, R. E., Ika-Sari, C., Eikelis, N., Straznicky, N., Lambert, G. W. & Esler, M. D., 3 Oct 2013, In : International Journal of Cardiology. 168, 3, p. 2214-2220 7 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Guideline for the diagnosis and management of hypertension in adults — 2016

Gabb, G. M., Mangoni, A., Anderson, C. S., Cowley, D., Dowden, J. S., Golledge, J., Hankey, G. J., Howes, F. S., Leckie, L., Perkovic, V., Schlaich, M., Zwar, N. A., Medley, T. L. & Arnolda, L., 18 Jul 2016, In : Medical Journal of Australia. 205, 2, p. 85-89

Research output: Contribution to journalArticle

Open Access
134 Citations (Scopus)

Higher heart rate increases risk of diabetes among men: The Australian Diabetes Obesity and Lifestyle (AusDiab) study

Grantham, N. M., Magliano, D. J., Tanamas, S. K., Söderberg, S., Schlaich, M. P. & Shaw, J. E., Apr 2013, In : Diabetic Medicine. 30, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

How to measure home blood pressure: Recommendations for healthcare professionals and patients

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2016, In : Australian Family Physician. 45, 1, p. 31-34

Research output: Contribution to journalArticle

10 Citations (Scopus)

Impact of nurse-mediated management on achieving blood pressure goal levels in primary care: Insights from the Valsartan Intensified Primary carE Reduction of Blood Pressure Study

Carrington, M. J., Jennings, G. L., Harris, M., Nelson, M., Schlaich, M., Stocks, N. P., Burrell, L. M., Amerena, J., De Looze, F. J., Swemmer, C. H., Kurstjens, N. P. & Stewart, S., 2016, In : European Journal of Cardiovascular Nursing. 15, 6, p. 409-416

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
22 Citations (Scopus)

International expert consensus statement: Percutaneous transluminal renal denervation for the treatment of resistant hypertension

Schlaich, M. P., Schmieder, R. E., Bakris, G., Blankestijn, P. J., Böhm, M., Campese, V. M., Francis, D. P., Grassi, G., Hering, D., Katholi, R., Kjeldsen, S., Krum, H., Mahfoud, F., Mancia, G., Messerli, F. H., Narkiewicz, K., Parati, G., Rocha-Singh, K. J., Ruilope, L. M., Rump, L. C. & 8 others, Sica, D. A., Sobotka, P. A., Tsioufis, C., Vonend, O., Weber, M. A., Williams, B., Zeller, T. & Esler, M. D., 3 Dec 2013, In : Journal of the American College of Cardiology. 62, 22, p. 2031-2045 15 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Muscle sympathetic nerve activity is associated with elements of the plasma lipidomic profile in young asian adults

Eikelis, N., Lambert, E. A., Phillips, S., Sari, C. I., Mundra, P. A., Weir, J. M., Huynh, K., Grima, M. T., Straznicky, N. E., Dixon, J. B., Schlaich, M. P., Meikle, P. J. & Lambert, G. W., 1 Jun 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 6, p. 2059-2068 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Neck circumference is associated with muscle sympathetic nerve activity in overweight and obese men but not women

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P., Phillips, S. E. & Lambert, E. A., 6 Apr 2017, In : Frontiers in Physiology. 8, APR, 203.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
230 Downloads (Pure)

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

430 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rationale and design of a large registry on renal denervation: The Global SYMPLICITY registry

Böhm, M., Mahfoud, F., Ukena, C., Bauer, A., Fleck, E., Hoppe, U. C., Kintscher, U., Narkiewicz, K., Negoita, M., Ruilope, L., Rump, L. C., Schlaich, M., Schmieder, R., Sievert, H., Weil, J., Williams, B., Zeymer, U. & Mancia, G., Aug 2013, In : EuroIntervention. 9, 4, p. 484-492 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Duval, J., Lee, R., Sata, Y., Krum, H., Lambert, E., Peter, K., Head, G., Lambert, G., Esler, M. D. & Schlaich, M., 1 Jan 2016, In : International Journal of Cardiology. 202, p. 388-393 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Renal artery denervation for treatment of patients with self-reported obstructive sleep apnea and resistant hypertension: Results from the Global SYMPLICITY Registry

Linz, D., Mancia, G., Mahfoud, F., Narkiewicz, K., Ruilope, L., Schlaich, M., Kindermann, I., Schmieder, R. E., Ewen, S., Williams, B. & Bohm, M., 2017, In : Journal of Hypertension. 35, 1, p. 148-153 6 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

Zaldivia, M. T. K., Rivera, J., Hering, D., Marusic, P., Sata, Y., Lim, B., Eikelis, N., Lee, R., Lambert, G. W., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Eisenhardt, S. U., Flierl, U., Schlaich, M. P. & Peter, K., 1 Feb 2017, In : Hypertension. 69, 2, p. 323-331 9 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
252 Downloads (Pure)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2 Citations (Scopus)

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2

Matthews, V. B., Elliot, R. H., Rudnicka, C., Hricova, J., Herat, L. & Schlaich, M. P., 1 Oct 2017, In : Journal of Hypertension. 35, 10, p. 2059–2068

Research output: Contribution to journalArticle

48 Citations (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)