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  • 2017
  • 2015
  • 2014
  • 2011

Author

  • Markus Schlaich
Article

ADAM19: A novel target for metabolic syndrome in humans and mice

Weerasekera, L., Rudnicka, C., Sang, Q. X., Curran, J. E., Johnson, M. P., Moses, E. K., Göring, H. H. H., Blangero, J., Hricova, J., Schlaich, M. & Matthews, V. B., 7 Feb 2017, In : Mediators of Inflammation. 2017, 9 p., 7281986.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Ambulatory blood pressure monitoring

National Heart Foundation and High Blood Pressure Research Council of Australia Ambulatory Blood Pressure Monitoring Consensus Committee, Nov 2011, In : Australian Family Physician. 40, 11, p. 877-880 4 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism

Marques, F. Z., Eikelis, N., Bayles, R. G., Lambert, E. A., Straznicky, N. E., Hering, D., Esler, M. D., Head, G. A., Barton, D. A., Schlaich, M. P. & Lambert, G. W., 1 Jan 2017, In : Molecular Psychiatry. 22, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Lambert, E. A., Sari, C. I., Eikelis, N., Nestel, P. J., Phillips, S. E., Hering, D., Karapanagiotidis, S., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Apr 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 4, p. 1544-1550 7 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., Hilgers, K. F. & Schmieder, R. E., Jun 2011, In : Pharmacogenetics and Genomics. 21, 6, p. 347-349 3 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage

Singh, R. R., Sajeesh, V., Booth, L. C., McArdle, Z., May, C. N., Head, G. A., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 28 Feb 2017, In : Journal of the American College of Cardiology. 69, 8, p. 951-964 14 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months

Symplicity HTN-1 Investigators & Schlaich, M., May 2011, In : Hypertension. 57, 5, p. 911-7 7 p.

Research output: Contribution to journalArticle

698 Citations (Scopus)

Change in sympathetic nerve firing pattern associated with dietary weight loss in the metabolic syndrome

Lambert, E., Straznicky, N. E., Dawood, T., Ika-Sari, C., Grima, M., Esler, M. D., Schlaich, M. P. & Lambert, G. W., Dec 2011, In : Frontiers in Physiology. 2, 52.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Device-based antihypertensive therapy: Therapeutic modulation of the autonomic nervous system

Krum, H., Sobotka, P., Mahfoud, F., Böhm, M., Esler, M. & Schlaich, M., 18 Jan 2011, In : Circulation. 123, 2, p. 209-215 7 p.

Research output: Contribution to journalArticle

Open Access
126 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Effect of renal denervation on kidney function in patients with chronic kidney disease

Hering, D., Marusic, P., Duval, J., Sata, Y., Head, G. A., Denton, K. M., Burrows, S., Walton, A. S., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 93-97 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
96 Citations (Scopus)

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 10 May 2011, In : Circulation. 123, 18, p. 1940-1946 7 p.

Research output: Contribution to journalArticle

Open Access
465 Citations (Scopus)

Effects of Moxonidine and Low-Calorie Diet: Cardiometabolic Benefits from Combination of Both Therapies

Lambert, E. A., Sari, C. I., Eikelis, N., Phillips, S. E., Grima, M., Straznicky, N. E., Dixon, J. B., Esler, M., Schlaich, M. P., Head, G. A. & Lambert, G. W., 1 Nov 2017, In : Obesity. 25, 11, p. 1894-1902 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of renal sympathetic denervation on urinary sodium excretion in patients with resistant hypertension

Pöss, J., Ewen, S., Schmieder, R. E., Muhler, S., Vonend, O., Ott, C., Linz, D., Geisel, J., Rump, L. C., Schlaich, M., Böhm, M. & Mahfoud, F., 29 Aug 2015, In : Clinical Research in Cardiology. 104, 8, p. 672-678 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Endothelial function in healthy young individuals is associated with dietary consumption of saturated fat

Lambert, E. A., Phillips, S., Belski, R., Tursunalieva, A., Eikelis, N., Sari, C. I., Dixon, J. B., Straznicky, N., Grima, M., Head, G. A., Schlaich, M. & Lambert, G. W., 9 Nov 2017, In : Frontiers in Physiology. 8, November, 876.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals

Straznicky, N. E., Grima, M. T., Lambert, E. A., Eikelis, N., Dawood, T., Lambert, G. W., Nestel, P. J., Masuo, K., Sari, C. I., Chopra, R., Mariani, J. A. & Schlaich, M. P., 1 Mar 2011, In : Journal of Hypertension. 29, 3, p. 553-564 12 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

123 Citations (Scopus)

Folic acid treatment normalizes nos-dependence of vascular tone in the metabolic syndrome

Schneider, M. P., Schlaich, M. P., Harazny, J. M., Raff, U., Ritt, M., Ott, C. & Schmieder, R. E., May 2011, In : Obesity. 19, 5, p. 960-967 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men

Lambert, E., Lambert, G., Ika-Sari, C., Dawood, T., Lee, K., Chopra, R., Straznicky, N., Eikelis, N., Drew, S., Tilbrook, A., Dixon, J., Esler, M. & Schlaich, M. P., 1 Jul 2011, In : Hypertension. 58, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Health-related quality of life and blood pressure 12months after renal denervation

Lambert, G. W., Hering, D., Marusic, P., Thorp, A., Sata, Y., Lee, R., Duval, J., Hammond, L., Head, G. A., Esler, M. D., Lambert, E. A., Dixon, J. B., Dhar, A. K., Barton, D. A. & Schlaich, M., Nov 2015, In : Journal of Hypertension. 33, 11, p. 2350-2358 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Home blood pressuremonitoring: Australian Expert Consensus Statement

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2015, In : Journal of Hypertension. 33, 9, p. 1721-1728

Research output: Contribution to journalArticle

45 Citations (Scopus)

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
34 Citations (Scopus)

Muscle sympathetic nerve activity is associated with elements of the plasma lipidomic profile in young asian adults

Eikelis, N., Lambert, E. A., Phillips, S., Sari, C. I., Mundra, P. A., Weir, J. M., Huynh, K., Grima, M. T., Straznicky, N. E., Dixon, J. B., Schlaich, M. P., Meikle, P. J. & Lambert, G. W., 1 Jun 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 6, p. 2059-2068 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Neck circumference is associated with muscle sympathetic nerve activity in overweight and obese men but not women

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P., Phillips, S. E. & Lambert, E. A., 6 Apr 2017, In : Frontiers in Physiology. 8, APR, 203.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
230 Downloads (Pure)

New developments in the pathogenesis of obesity-induced hypertension

Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. & Jordan, J., 2015, In : Journal of Hypertension. 33, 8, p. 1499-1508

Research output: Contribution to journalArticle

50 Citations (Scopus)

Opposing effects of shear-mediated dilation and myogenic constriction on artery diameter in response to handgrip exercise in humans

Atkinson, C., Carter, H., Naylor, L., Dawson, E. A., Marusic, P., Hering, D., Schlaich, M., Thijssen, D. H. J. & Green, D. J., 15 Oct 2015, In : Journal of Applied Physiology. 119, 8, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
366 Downloads (Pure)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

430 Citations (Scopus)

Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Richards, K., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Jul 2015, In : Metabolism: clinical and experimental. 64, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Recurrent postural vasovagal syncope: Sympathetic nervous system phenotypes

Vaddadi, G., Guo, L., Esler, M., Socratous, F., Schlaich, M., Chopra, R., Eikelis, N., Lambert, G., Trauer, T. & Lambert, E., Oct 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Reduction in basal nitric oxide activity causes albuminuria

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. & Schmieder, R. E., Feb 2011, In : Diabetes. 60, 2, p. 572-576 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss

Straznicky, N. E., Grima, M. T., Sari, C. I., Lambert, E. A., Phillips, S. E., Eikelis, N., Kobayashi, D., Hering, D., Mariani, J. A., Dixon, J. B., Nestel, P. J., Karapanagiotidis, S., Schlaich, M. P. & Lambert, G. W., 22 Aug 2015, In : Cardiovascular Diabetology. 14, 1, 113.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Reinnervation following catheter-based radio-frequency renal denervation

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 20 Apr 2015, In : Experimental Physiology. 100, 5, p. 485-490 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 21 Feb 2015, In : Hypertension. 65, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Open Access
82 Citations (Scopus)

Relation between QT interval variability and cardiac sympathetic activity in hypertension

Baumert, M., Schlaich, M. P., Nalivaiko, E., Lambert, E., Sari, C. I., Kaye, D. M., Elser, M. D., Sanders, P. & Lambert, G., Apr 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 4

Research output: Contribution to journalArticle

71 Citations (Scopus)

Relevance of sympathetic nervous system activation in obesity and metabolic syndrome

Thorp, A. A. & Schlaich, M., 2015, In : Journal of Diabetes Research. 2015, p. 1-11

Research output: Contribution to journalArticle

Open Access
File
147 Citations (Scopus)
227 Downloads (Pure)

Renal artery denervation for treatment of patients with self-reported obstructive sleep apnea and resistant hypertension: Results from the Global SYMPLICITY Registry

Linz, D., Mancia, G., Mahfoud, F., Narkiewicz, K., Ruilope, L., Schlaich, M., Kindermann, I., Schmieder, R. E., Ewen, S., Williams, B. & Bohm, M., 2017, In : Journal of Hypertension. 35, 1, p. 148-153 6 p.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Renal denervation: A potential new treatment modality for polycystic ovary syndrome?

Schlaich, M. P., Straznicky, N., Grima, M., Ika-Sari, C., Dawood, T., Mahfoud, F., Lambert, E., Chopra, R., Socratous, F., Hennebry, S., Eikelis, N., Böhm, M., Krum, H., Lambert, G., Esler, M. D. & Sobotka, P. A., May 2011, In : Journal of Hypertension. 29, 5, p. 991-996 6 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Renal denervation and hypertension

Schlaich, M. P., Krum, H., Sobotka, P. A. & Esler, M. D., Jun 2011, In : American Journal of Hypertension. 24, 6, p. 635-642 8 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

Zaldivia, M. T. K., Rivera, J., Hering, D., Marusic, P., Sata, Y., Lim, B., Eikelis, N., Lee, R., Lambert, G. W., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Eisenhardt, S. U., Flierl, U., Schlaich, M. P. & Peter, K., 1 Feb 2017, In : Hypertension. 69, 2, p. 323-331 9 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
252 Downloads (Pure)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)