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  • 2017
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  • 2011

Author

  • Markus Schlaich
Article

ADAM19: A novel target for metabolic syndrome in humans and mice

Weerasekera, L., Rudnicka, C., Sang, Q. X., Curran, J. E., Johnson, M. P., Moses, E. K., Göring, H. H. H., Blangero, J., Hricova, J., Schlaich, M. & Matthews, V. B., 7 Feb 2017, In : Mediators of Inflammation. 2017, 9 p., 7281986.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Ambulatory blood pressure monitoring

National Heart Foundation and High Blood Pressure Research Council of Australia Ambulatory Blood Pressure Monitoring Consensus Committee, Nov 2011, In : Australian Family Physician. 40, 11, p. 877-880 4 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Anatomical and procedural determinants of catheter-based renal denervation

Ewen, S., Ukena, C., Lüscher, T. F., Bergmann, M., Blankestijn, P. J., Blessing, E., Cremers, B., Dörr, O., Hering, D., Kaiser, L., Nef, H., Noory, E., Schlaich, M., Sharif, F., Sudano, I., Vogel, B., Voskuil, M., Zeller, T., Tzafriri, A. R., Edelman, E. R. & 4 others, Lauder, L., Scheller, B., Böhm, M. & Mahfoud, F., 1 Oct 2016, In : Cardiovascular Revascularization Medicine. 17, 7, p. 474-479 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

A polymorphism in the norepinephrine transporter gene is associated with affective and cardiovascular disease through a microRNA mechanism

Marques, F. Z., Eikelis, N., Bayles, R. G., Lambert, E. A., Straznicky, N. E., Hering, D., Esler, M. D., Head, G. A., Barton, D. A., Schlaich, M. P. & Lambert, G. W., 1 Jan 2017, In : Molecular Psychiatry. 22, 1, p. 134-141 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Arterial norepinephrine concentration is inversely and independently associated with insulin clearance in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Lambert, E. A., Sari, C. I., Eikelis, N., Nestel, P. J., Phillips, S. E., Hering, D., Karapanagiotidis, S., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Apr 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 4, p. 1544-1550 7 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Association of (pro)renin receptor gene polymorphism with blood pressure in Caucasian men

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P., Hilgers, K. F. & Schmieder, R. E., Jun 2011, In : Pharmacogenetics and Genomics. 21, 6, p. 347-349 3 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage

Singh, R. R., Sajeesh, V., Booth, L. C., McArdle, Z., May, C. N., Head, G. A., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 28 Feb 2017, In : Journal of the American College of Cardiology. 69, 8, p. 951-964 14 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
166 Citations (Scopus)

Catheter-based renal sympathetic denervation for resistant hypertension: durability of blood pressure reduction out to 24 months

Symplicity HTN-1 Investigators & Schlaich, M., May 2011, In : Hypertension. 57, 5, p. 911-7 7 p.

Research output: Contribution to journalArticle

695 Citations (Scopus)

Change in sympathetic nerve firing pattern associated with dietary weight loss in the metabolic syndrome

Lambert, E., Straznicky, N. E., Dawood, T., Ika-Sari, C., Grima, M., Esler, M. D., Schlaich, M. P. & Lambert, G. W., Dec 2011, In : Frontiers in Physiology. 2, 52.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Chronic depression symptoms and salivary NOx are associated with retinal vascular dysregulation: The SABPA study

Malan, L., Hamer, M., Von Känel, R., Schlaich, M., Reimann, M., Frasure-Smith, N., Lambert, G. W., Vilser, W., Harvey, B. H., Steyn, F. & Malan, N. T., 2016, In : Nitric Oxide - Biology and Chemistry. 55-56, p. 10-17

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Device-based antihypertensive therapy: Therapeutic modulation of the autonomic nervous system

Krum, H., Sobotka, P., Mahfoud, F., Böhm, M., Esler, M. & Schlaich, M., 18 Jan 2011, In : Circulation. 123, 2, p. 209-215 7 p.

Research output: Contribution to journalArticle

Open Access
124 Citations (Scopus)

Device-based approaches for renal nerve ablation for hypertension and beyond

Thorp, A. A. & Schlaich, M., 8 Jul 2015, In : Frontiers in Physiology. 6, p. 1-13 13 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: A double-blind, randomized, crossover trial

De Courten, B., De Courten, M. P. J., Soldatos, G., Dougherty, S. L., Straznicky, N., Schlaich, M., Sourris, K. C., Chand, V., Scheijen, J. L. J. M., Kingwell, B. A., Cooper, M. E., Schalkwijk, C. G., Walker, K. Z. & Forbes, J. M., 1 Jun 2016, In : American Journal of Clinical Nutrition. 103, 6, p. 1426-1433 8 p.

Research output: Contribution to journalArticle

Open Access
55 Citations (Scopus)

Effect of renal denervation on kidney function in patients with chronic kidney disease

Hering, D., Marusic, P., Duval, J., Sata, Y., Head, G. A., Denton, K. M., Burrows, S., Walton, A. S., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : International Journal of Cardiology. 232, p. 93-97 5 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
96 Citations (Scopus)

Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: A pilot study

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 10 May 2011, In : Circulation. 123, 18, p. 1940-1946 7 p.

Research output: Contribution to journalArticle

Open Access
465 Citations (Scopus)

Effects of Moxonidine and Low-Calorie Diet: Cardiometabolic Benefits from Combination of Both Therapies

Lambert, E. A., Sari, C. I., Eikelis, N., Phillips, S. E., Grima, M., Straznicky, N. E., Dixon, J. B., Esler, M., Schlaich, M. P., Head, G. A. & Lambert, G. W., 1 Nov 2017, In : Obesity. 25, 11, p. 1894-1902 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Effects of renal sympathetic denervation on urinary sodium excretion in patients with resistant hypertension

Pöss, J., Ewen, S., Schmieder, R. E., Muhler, S., Vonend, O., Ott, C., Linz, D., Geisel, J., Rump, L. C., Schlaich, M., Böhm, M. & Mahfoud, F., 29 Aug 2015, In : Clinical Research in Cardiology. 104, 8, p. 672-678 7 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Endothelial function in healthy young individuals is associated with dietary consumption of saturated fat

Lambert, E. A., Phillips, S., Belski, R., Tursunalieva, A., Eikelis, N., Sari, C. I., Dixon, J. B., Straznicky, N., Grima, M., Head, G. A., Schlaich, M. & Lambert, G. W., 9 Nov 2017, In : Frontiers in Physiology. 8, November, 876.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)

Exercise augments weight loss induced improvement in renal function in obese metabolic syndrome individuals

Straznicky, N. E., Grima, M. T., Lambert, E. A., Eikelis, N., Dawood, T., Lambert, G. W., Nestel, P. J., Masuo, K., Sari, C. I., Chopra, R., Mariani, J. A. & Schlaich, M. P., 1 Mar 2011, In : Journal of Hypertension. 29, 3, p. 553-564 12 p.

Research output: Contribution to journalArticle

62 Citations (Scopus)

First report of the global SYMPLICITY registry on the effect of renal artery denervation in patients with uncontrolled hypertension

Böhm, M., Mahfoud, F., Ukena, C., Hoppe, U. C., Narkiewicz, K., Negoita, M., Ruilope, L., Schlaich, M., Schmieder, R. E., Whitbourn, R., Williams, B., Zeymer, U., Zirlik, A. & Mancia, G., 2015, In : Hypertension. 65, 4, p. 766-774

Research output: Contribution to journalArticle

122 Citations (Scopus)

Folic acid treatment normalizes nos-dependence of vascular tone in the metabolic syndrome

Schneider, M. P., Schlaich, M. P., Harazny, J. M., Raff, U., Ritt, M., Ott, C. & Schmieder, R. E., May 2011, In : Obesity. 19, 5, p. 960-967 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Ghrelin modulates sympathetic nervous system activity and stress response in lean and overweight men

Lambert, E., Lambert, G., Ika-Sari, C., Dawood, T., Lee, K., Chopra, R., Straznicky, N., Eikelis, N., Drew, S., Tilbrook, A., Dixon, J., Esler, M. & Schlaich, M. P., 1 Jul 2011, In : Hypertension. 58, 1, p. 43-50 8 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Guideline for the diagnosis and management of hypertension in adults — 2016

Gabb, G. M., Mangoni, A., Anderson, C. S., Cowley, D., Dowden, J. S., Golledge, J., Hankey, G. J., Howes, F. S., Leckie, L., Perkovic, V., Schlaich, M., Zwar, N. A., Medley, T. L. & Arnolda, L., 18 Jul 2016, In : Medical Journal of Australia. 205, 2, p. 85-89

Research output: Contribution to journalArticle

Open Access
128 Citations (Scopus)

Health-related quality of life and blood pressure 12months after renal denervation

Lambert, G. W., Hering, D., Marusic, P., Thorp, A., Sata, Y., Lee, R., Duval, J., Hammond, L., Head, G. A., Esler, M. D., Lambert, E. A., Dixon, J. B., Dhar, A. K., Barton, D. A. & Schlaich, M., Nov 2015, In : Journal of Hypertension. 33, 11, p. 2350-2358 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Home blood pressuremonitoring: Australian Expert Consensus Statement

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2015, In : Journal of Hypertension. 33, 9, p. 1721-1728

Research output: Contribution to journalArticle

41 Citations (Scopus)

How to measure home blood pressure: Recommendations for healthcare professionals and patients

Sharman, J. E., Howes, F. S., Head, G. A., Mcgrath, B. P., Stowasser, M., Schlaich, M., Glasziou, P. & Nelson, M. R., 2016, In : Australian Family Physician. 45, 1, p. 31-34

Research output: Contribution to journalArticle

9 Citations (Scopus)

Impact of nurse-mediated management on achieving blood pressure goal levels in primary care: Insights from the Valsartan Intensified Primary carE Reduction of Blood Pressure Study

Carrington, M. J., Jennings, G. L., Harris, M., Nelson, M., Schlaich, M., Stocks, N. P., Burrell, L. M., Amerena, J., De Looze, F. J., Swemmer, C. H., Kurstjens, N. P. & Stewart, S., 2016, In : European Journal of Cardiovascular Nursing. 15, 6, p. 409-416

Research output: Contribution to journalArticle

3 Citations (Scopus)

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Muscle sympathetic nerve activity is associated with elements of the plasma lipidomic profile in young asian adults

Eikelis, N., Lambert, E. A., Phillips, S., Sari, C. I., Mundra, P. A., Weir, J. M., Huynh, K., Grima, M. T., Straznicky, N. E., Dixon, J. B., Schlaich, M. P., Meikle, P. J. & Lambert, G. W., 1 Jun 2017, In : Journal of Clinical Endocrinology and Metabolism. 102, 6, p. 2059-2068 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Neck circumference is associated with muscle sympathetic nerve activity in overweight and obese men but not women

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P., Phillips, S. E. & Lambert, E. A., 6 Apr 2017, In : Frontiers in Physiology. 8, APR, 203.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
226 Downloads (Pure)

New developments in the pathogenesis of obesity-induced hypertension

Kotsis, V., Nilsson, P., Grassi, G., Mancia, G., Redon, J., Luft, F., Schmieder, R., Engeli, S., Stabouli, S., Antza, C., Pall, D., Schlaich, M. & Jordan, J., 2015, In : Journal of Hypertension. 33, 8, p. 1499-1508

Research output: Contribution to journalArticle

50 Citations (Scopus)

Opposing effects of shear-mediated dilation and myogenic constriction on artery diameter in response to handgrip exercise in humans

Atkinson, C., Carter, H., Naylor, L., Dawson, E. A., Marusic, P., Hering, D., Schlaich, M., Thijssen, D. H. J. & Green, D. J., 15 Oct 2015, In : Journal of Applied Physiology. 119, 8, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
361 Downloads (Pure)

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

427 Citations (Scopus)

Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Richards, K., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Jul 2015, In : Metabolism: clinical and experimental. 64, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Recurrent postural vasovagal syncope: Sympathetic nervous system phenotypes

Vaddadi, G., Guo, L., Esler, M., Socratous, F., Schlaich, M., Chopra, R., Eikelis, N., Lambert, G., Trauer, T. & Lambert, E., Oct 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Reduction in basal nitric oxide activity causes albuminuria

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. & Schmieder, R. E., Feb 2011, In : Diabetes. 60, 2, p. 572-576 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss

Straznicky, N. E., Grima, M. T., Sari, C. I., Lambert, E. A., Phillips, S. E., Eikelis, N., Kobayashi, D., Hering, D., Mariani, J. A., Dixon, J. B., Nestel, P. J., Karapanagiotidis, S., Schlaich, M. P. & Lambert, G. W., 22 Aug 2015, In : Cardiovascular Diabetology. 14, 1, 113.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Reinnervation following catheter-based radio-frequency renal denervation

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 20 Apr 2015, In : Experimental Physiology. 100, 5, p. 485-490 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 21 Feb 2015, In : Hypertension. 65, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Open Access
80 Citations (Scopus)

Relation between QT interval variability and cardiac sympathetic activity in hypertension

Baumert, M., Schlaich, M. P., Nalivaiko, E., Lambert, E., Sari, C. I., Kaye, D. M., Elser, M. D., Sanders, P. & Lambert, G., Apr 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 4

Research output: Contribution to journalArticle

71 Citations (Scopus)