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• Article

  A comparison of the endotoxin biosynthesis and protein oxidation pathways in the biogenesis of the outer membrane of Escherichia coli and Neisseria meningitidis

  Piek, S. & Kahler, C., 2012, In : Frontiers in Cellular and Infection Microbiology. 2, p. 1-23

  Research output: Contribution to journal › Article

  Open Access
  10 Citations (Scopus)

• Attachment and Invasion of Neisseria meningitidis to Host Cells Is Related to Surface Hydrophobicity, Bacterial Cell Size and Capsule

  Bartley, S., Tzeng, Y-L., Heel, K., Lee, C. W., Mowlaboccus, S., Seemann, T., Lu, W., Lin, Y-H., Ryan, C. S., Peacock, C., Stephens, D. S., Davies, J. K. & Kahler, C., 2013, In : PLoS One. 8, 2, p. 15pp

  Research output: Contribution to journal › Article

  Open Access

  File
  31 Citations (Scopus)

  461 Downloads (Pure)

• B Part of It protocol: A cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of Neisseria meningitidis in adolescents

  Marshall, H. S., McMillan, M., Koehler, A., Lawrence, A., Maclennan, J. M., Maiden, M. C. J., Ramsay, M., Ladhani, S. N., Trotter, C., Borrow, R., Finn, A., Sullivan, T., Richmond, P., Kahler, C. M., Whelan, J. & Vadivelu, K., 1 Jul 2018, In : BMJ Open. 8, 7, e020988.

  Research output: Contribution to journal › Article

  Open Access

  • 4CMenB vaccine
  • Neisseria meningitidis
  • South Australia
  • Students
  • Randomized Controlled Trials
  16 Citations (Scopus)

• Characterization of DsbD in Neisseria meningitidis

  Kumar, P., Sannigrahi, S., Scoullar, J., Kahler, C. & Tzeng, Y. L., 2011, In : Molecular Microbiology. 79, 6, p. 1557-1573

  Research output: Contribution to journal › Article

  • Neisseria meningitidis
  • Disulfides
  • Protein Folding
  • Electrophoretic Mobility Shift Assay
  • Cytochromes c
  19 Citations (Scopus)

• Cloning, expression, purification and crystallization of an endotoxin-biosynthesis enzyme from Neisseria meningitidis

  Anandan, A., Piek, S., Kahler, C. & Vrielink, A., 1 Dec 2012, In : ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 68, 12, p. 1494-1497

  Research output: Contribution to journal › Article

  Open Access

  File

  • endotoxins
  • Biosynthesis
  • biosynthesis
  • Cloning
  • Neisseria meningitidis
  4 Citations (Scopus)

  266 Downloads (Pure)

• Genomic epidemiology and population structure of Neisseria gonorrhoeae from remote highly endemic Western Australian populations

  Al Suwayyid, B. A., Coombs, G. W., Speers, D. J., Pearson, J., Wise, M. J. & Kahler, C. M., 27 Feb 2018, In : BMC Genomics. 19, 1, 165.

  Research output: Contribution to journal › Article

  Open Access

  • Metagenomics
  • Neisseria gonorrhoeae
  • Western Australia
  • Epidemiology
  • Gonorrhea
  10 Citations (Scopus)

• Influence of in situ progressive N-terminal is still controversial truncation of glycogen branching enzyme in Escherichia coli DH5α on glycogen structure, accumulation, and bacterial viability

  Wang, L., Regina, A., Butardo, V. M., Kosar-Hashemi, B., Larroque, O., Kahler, C. & Wise, M., 2015, In : BMC Microbiology. 15, 96, p. 1-14

  Research output: Contribution to journal › Article

  Open Access

  • 1,4-alpha-Glucan Branching Enzyme
  • Microbial Viability
  • Glycogen
  • Escherichia coli
  • Desiccation
  9 Citations (Scopus)

• Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity

  Reimer, A., Seufert, F., Weiwad, M., Ebert, J., Bzdyl, N. M., Kahler, C. M., Sarkar-Tyson, M., Holzgrabe, U., Rudel, T. & Kozjak-Pavlovic, V., 1 Oct 2016, In : International Journal of Antimicrobial Agents. 48, 4, p. 401-408 8 p.

  Research output: Contribution to journal › Article

  • Peptidylprolyl Isomerase
  • Virulence
  • Macrophages
  • Neisseria meningitidis
  • Neisseria gonorrhoeae
  14 Citations (Scopus)

• Meningococcal B vaccine and meningococcal carriage in adolescents in Australia

  Marshall, H. S., McMillan, M., Koehler, A. P., Lawrence, A., Sullivan, T. R., MacLennan, J. M., Maiden, M. C. J., Ladhani, S. N., Ramsay, M. E., Trotter, C., Borrow, R., Finn, A., Kahler, C. M., Whelan, J., Vadivelu, K. & Richmond, P., 23 Jan 2020, In : New England Journal of Medicine. 382, 4, p. 318-327 10 p.

  Research output: Contribution to journal › Article

  • Meningococcal Vaccines
  • Neisseria meningitidis
  • Odds Ratio
  • Confidence Intervals
  • 4CMenB vaccine
  35 Citations (Scopus)

• Meningococcal Disease-Associated Prophage-Like Elements Are Present in Neisseria gonorrhoeae and Some Commensal Neisseria Species

  Al Suwayyid, B. A., Rankine-Wilson, L., Speers, D. J., Wise, M. J., Coombs, G. W. & Kahler, C. M., 8 Feb 2020, In : Genome Biology and Evolution. 12, 2, p. 3938-3950 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Neisseria
  • Prophages
  • commensal
  • Meningococcal Infections
  • Neisseria gonorrhoeae

• Moraxella catarrhalis Restriction-Modification Systems Are Associated with Phylogenetic Lineage and Disease

  Blakeway, L. V., Tan, A., Lappan, R., Ariff, A., Pickering, J. L., Peacock, C. S., Blyth, C. C., Kahler, C. M., Chang, B. J., Lehmann, D., Kirkham, L-A. S., Murphy, T. F., Jennings, M. P., Bakaletz, L. O., Atack, J. M., Peak, I. R. & Seib, K. L., 1 Nov 2018, In : Genome Biology and Evolution. 10, 11, p. 2932-2946 15 p.

  Research output: Contribution to journal › Article

  Open Access

  • DNA Restriction-Modification Enzymes
  • Moraxella catarrhalis
  • Moraxella (Branhamella) catarrhalis
  • restriction endonucleases
  • phylogenetics
  9 Citations (Scopus)

• Novel Moraxella catarrhalis prophages display hyperconserved non-structural genes despite their genomic diversity

  Ariff, A., Wise, M., Kahler, C., Tay, A. C. Y., Peters, F., Perkins, T. & Chang, B., 24 Oct 2015, In : BMC Genomics. 16, 1, p. 1-19 19 p., 860.

  Research output: Contribution to journal › Article

  Open Access

  • Prophages
  • Moraxella (Branhamella) catarrhalis
  • Genes
  • Bacteriophages
  • Virulence
  9 Citations (Scopus)

• Production, biophysical characterization and initial crystallization studies of the N- and C-terminal domains of DsbD, an essential enzyme in Neisseria meningitidis

  Smith, R. P., Whitten, A. E., Paxman, J. J., Kahler, C. M., Scanlon, M. J. & Heras, B., 2018, In : Acta Crystallographica. Section F: Structural Biology Communications. 74, 1, p. 31-38 8 p.

  Research output: Contribution to journal › Article

  • Pathogens
  • Neisseria meningitidis
  • Crystallization
  • Purification
  • enzymes
  1 Citation (Scopus)

• Sticky and sweet: the role of post-translational modifications on neisserial pili

  Kahler, C., 2011, In : Frontiers in Microbiology. 2, p. 1-3

  Research output: Contribution to journal › Article

  Open Access
  2 Citations (Scopus)

• Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens

  Smith, R. P., Mohanty, B., Mowlaboccus, S., Paxman, J. J., Williams, M. L., Headey, S. J., Wang, G., Subedi, P., Doak, B. C., Kahler, C. M., Scanlon, M. J. & Heras, B., 26 Oct 2018, In : Journal of Biological Chemistry. 293, 43, p. 16559-16571 13 p.

  Research output: Contribution to journal › Article
  3 Citations (Scopus)

• Temporal changes in BEXSERO® antigen sequence type associated with genetic lineages of Neisseria meningitidis over a 15-year period in Western Australia

  Mowlaboccus, S., Perkins, T., Smith, H., Sloots, T., Tozer, S., Prempeh, L., Tay, A. C. Y., Peters, F., Speers, D., Keil, A. D. & Kahler, C., 29 Jun 2016, In : PLoS One. 11, 6

  Research output: Contribution to journal › Article

  Open Access

  • Western Australia
  • Neisseria meningitidis
  • Antigens
  • Meningococcal Infections
  • Vaccines
  17 Citations (Scopus)

• The structure of the neisserial lipooligosaccharide phosphoethanolamine transferase A (LptA) required for resistance to polymyxin

  Wanty, C., Anandan, A., Piek, S., Walshe, J., Ganguly, J., Carlson, R. W., Stubbs, K., Kahler, C. & Vrielink, A., 2013, In : Journal of Molecular Biology. 425, 18, p. 3389-3402

  Research output: Contribution to journal › Article
  63 Citations (Scopus)
• Editorial

  The Goldilocks Zone: Searching for a Phylogenetic Approach for the Recombinogenic Neisseria gonorrhoeae

  Kahler, C. M., 9 Nov 2020, In : The Journal of infectious diseases. 222, 11, p. 1762-1763 2 p.

  Research output: Contribution to journal › Editorial
• Review article

  Enzyme targets for drug design of new anti-virulence therapeutics

  Kahler, C. M., Sarkar-Tyson, M., Kibble, E. A., Stubbs, K. A. & Vrielink, A., 1 Dec 2018, In : Current Opinion in Structural Biology. 53, p. 140-150 11 p.

  Research output: Contribution to journal › Review article

  Open Access

  File

  • Drug Design
  • Virulence
  • Enzymes
  • cis-trans-Isomerases
  • Protein Disulfide Reductase (Glutathione)
  6 Citations (Scopus)

  673 Downloads (Pure)

• Multidrug-resistant Neisseria gonorrhoeae: Future therapeutic options

  Kahler, C. M., 1 Apr 2018, In : Future Microbiology. 13, 5, p. 499-501 3 p.

  Research output: Contribution to journal › Review article
  2 Citations (Scopus)

• Structure-function relationships of the neisserial EptA enzyme responsible for phosphoethanolamine decoration of lipid A: Rationale for drug targeting

  Kahler, C. M., Nawrocki, K. L., Anandan, A., Vrielink, A. & Shafer, W. M., 21 Aug 2018, In : Frontiers in Microbiology. 9, JUL, 1922.

  Research output: Contribution to journal › Review article

  Open Access

  • phosphorylethanolamine
  • Lipid A
  • Drug Delivery Systems
  • Enzymes
  • Endotoxins
  8 Citations (Scopus)