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Author

  • Markus Schlaich

Renal Denervation in High-Risk Patients With Hypertension

Mahfoud, F., Mancia, G., Schmieder, R., Narkiewicz, K., Ruilope, L., Schlaich, M., Whitbourn, R., Zirlik, A., Zeller, T., Stawowy, P., Cohen, S. A., Fahy, M. & Böhm, M., 16 Jun 2020, In : Journal of the American College of Cardiology. 75, 23, p. 2879-2888 10 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Renal denervation in human hypertension: Mechanisms, current findings, and future prospects

Schlaich, M. P., Hering, D., Sobotka, P. A., Krum, H. & Esler, M. D., 1 Jun 2012, In : Current Hypertension Reports. 14, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation in moderate to severe CKD

Hering, D., Mahfoud, F., Walton, A. S., Krum, H., Lambert, G. W., Lambert, E. A., Sobotka, P. A., Böhm, M., Cremers, B., Esler, M. D. & Schlaich, M. P., 1 Jul 2012, In : Journal of the American Society of Nephrology. 23, 7, p. 1250-1257 8 p.

Research output: Contribution to journalArticle

Open Access
272 Citations (Scopus)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Cremers, B., Janker, J., Link, B., Vonend, O., Ukena, C., Linz, D., Schmieder, R., Rump, L. C., Kindermann, I., Sobotka, P. A., Krum, H., Scheller, B., Schlaich, M., Laufs, U. & Böhm, M., 1 Aug 2012, In : Hypertension. 60, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

Open Access
241 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal nerve ablation reduces blood pressure in a patient with renovascular hypertension resistant to drug and revascularisation therapies

Hering, D., Walton, A., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 23 Aug 2012, In : International Journal of Cardiology. 159, 2

Research output: Contribution to journalArticle

9 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Renal sympathetic denervation for treatment of drug-resistant hypertension: One-year results from the symplicity htn-2 randomized, controlled trial

Esler, M. D., Krum, H., Schlaich, M., Schmieder, R. E., Böhm, M. & Sobotka, P. A., 18 Dec 2012, In : Circulation. 126, 25, p. 2976-2982 7 p.

Research output: Contribution to journalArticle

Open Access
357 Citations (Scopus)

Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial

Stoiber, L., Mahfoud, F., Zamani, S. M., Lapinskas, T., Böhm, M., Ewen, S., Kulenthiran, S., Schlaich, M. P., Esler, M. D., Hammer, T., Stensæth, K. H., Pieske, B., Dreysse, S., Fleck, E., Kühne, T., Kelm, M., Stawowy, P. & Kelle, S., 1 Aug 2018, In : Clinical Research in Cardiology. 107, 8, p. 642-652 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2 Citations (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)

Rosuvastatin improves pulse wave reflection by restoring endothelial function

Ott, C., Schneider, M. P., Schlaich, M. P. & Schmieder, R. E., Jul 2012, In : Microvascular Research. 84, 1, p. 60-64 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

SGLT2 Inhibitor–Induced Sympathoinhibition: A Novel Mechanism for Cardiorenal Protection

Herat, L. Y., Magno, A. L., Rudnicka, C., Hricova, J., Carnagarin, R., Ward, N. C., Arcambal, A., Kiuchi, M. G., Head, G. A., Schlaich, M. P. & Matthews, V. B., Feb 2020, In : JACC: Basic to Translational Science. 5, 2, p. 169-179 11 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Booth, L. C., Schlaich, M. P., Nishi, E. E., Yao, S. T., Xu, J., Ramchandra, R., Lambert, G. W. & May, C. N., 1 Jul 2015, In : International Journal of Cardiology. 190, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
75 Downloads (Pure)

Single-unit muscle sympathetic nervous activity and its relation to cardiac noradrenaline spillover

Lambert, E. A., Schlaich, M. P., Dawood, T., Sari, C., Chopra, R., Barton, D. A., Kaye, D. M., Elam, M., Esler, M. D. & Lambert, G. W., May 2011, In : Journal of Physiology. 589, 10, p. 2597-2605 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Sodium glucose co-transporter 2 inhibition reduces succinate levels in diabetic mice

Herat, L. Y., Ward, N. C., Magno, A. L., Rakoczy, E. P., Kiuchi, M. G., Schlaich, M. P. & Matthews, V. B., 21 Jun 2020, In : World Journal of Gastroenterology. 26, 23, p. 3225-3235 11 p.

Research output: Contribution to journalArticle

Open Access

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
249 Citations (Scopus)

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients

Zaldivia, M. T. K., Hering, D., Marusic, P., Sata, Y., Lee, R., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Flierl, U., Wang, X., Drummond, G. R., Walton, A., Gardiner, E. E., Andrews, R. K., Schlaich, M. P. & Peter, K., Jan 2019, In : Cardiovascular Research. 116, 1, p. 202-210

Research output: Contribution to journalArticle

2 Citations (Scopus)

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation

Singh, R. R., McArdle, Z. M., Iudica, M., Easton, L. K., Booth, L. C., May, C. N., Parkington, H. C., Lombardo, P., Head, G. A., Lambert, G., Moritz, K. M., Schlaich, M. P. & Denton, K. M., Mar 2019, In : Hypertension. 73, 3, p. 718-727 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Krum, H., Narkiewicz, K., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 2014, In : Hypertension. 64, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Sympathetic activation and endothelial dysfunction in polycystic ovary syndrome are not explained by either obesity or insulin resistance

Lambert, E. A., Teede, H., Sari, C. I., Jona, E., Shorakae, S., Woodington, K., Hemmes, R., Eikelis, N., Straznicky, N. E., De Courten, B., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Dec 2015, In : Clinical Endocrinology. 83, 6, p. 812-819 8 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Sympathetic and vascular dysfunction in adult patients with Fontan circulation

Lambert, E., D'Udekem, Y., Cheung, M., Sari, C. I., Inman, J., Ahimastos, A., Eikelis, N., Pathak, A., King, I., Grigg, L., Schlaich, M. & Lambert, G., 20 Aug 2013, In : International Journal of Cardiology. 167, 4, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

27 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The effects of dietary weight loss with or without exercise training on liver enzymes in obese metabolic syndrome subjects

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Nestel, P. J., Dawood, T., Schlaich, M. P., Masuo, K., Chopra, R., Sari, C. I., Dixon, J. B., Tilbrook, A. J. & Lambert, G. W., 2012, In : Diabetes, Obesity and Metabolism. 14, 2, p. 139-148 10 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components

Straznicky, N. E., Grima, M. T., Eikelis, N., Nestel, P. J., Dawood, T., Schlaich, M. P., Chopra, R., Masuo, K., Esler, M. D., Sari, C. I., Lambert, G. W. & Lambert, E. A., Mar 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 3

Research output: Contribution to journalArticle

Open Access
73 Citations (Scopus)

The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Karapanagiotidis, S., Wong, C., Eikelis, N., Richards, K. L., Lee, G., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P. & Lambert, E. A., 1 Feb 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 2

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

The Schlager mouse as a model of altered retinal phenotype

Herat, L., Magno, A., Kiuchi, M., Jackson, K., Carnagarin, R., Head, G., Schlaich, M. & Matthews, V., Mar 2020, In : Neural Regeneration Research. 15, 3, p. 512-518 7 p.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

5 Citations (Scopus)

Type 2 diabetes strengthens the association between pulse pressure and chronic kidney disease: The AusDiab study

Van Den Hurk, K., Magliano, D. J., Alssema, M., Schlaich, M. P., Atkins, R. C., Reutens, A. T., Nijpels, G., Dekker, J. M. & Shaw, J. E., May 2011, In : Journal of Hypertension. 29, 5, p. 953-960 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

White Coat Hypertension-A Case for Assessing Vascular Age?

Climie, R. E., Lambert, E. A., Schlaich, M. P. & Lambert, G. W., 18 Jul 2020, In : American Journal of Hypertension. 33, 7, p. 599-601 3 p.

Research output: Contribution to journalArticle

Book

Renal denervation: A new approach to treatment of resistant hypertension

Heuser, R. R. (ed.), Schlaich, M. (ed.) & Sievert, H. (ed.), 2015, New York: Springer-Verlag London Ltd. 201 p.

Research output: Book/ReportBook

Chapter

Device-based approaches to target renal sympathetic nerves for hypertension

Schlaich, M. & Esler, M. D., 2016, Surgery of the Autonomic Nervous System. Hyam, J. A., Pereira, E. A. C. & Green, A. L. (eds.). Oxford University Press

Research output: Chapter in Book/Conference paperChapter

Devices for Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2013, Hypertension: A Companion to Braunwald's Heart Disease: Second Edition. Elsevier, p. 230-235 6 p.

Research output: Chapter in Book/Conference paperChapter

Heart/Kidney interactions

Schlaich, M., 19 Dec 2018, The ESC Textbook of Cardiovascular Medicine. Camm, A. J., Lüscher, T. F., Maurer, G. & Serruys, P. W. (eds.). 3 ed. Oxford University Press

Research output: Chapter in Book/Conference paperChapter

Interventional Treatments for Resistant Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2014, Comprehensive Clinical Nephrology . Johnson, R., Feehally, J. & Floege, J. (eds.). 5 ed. Philadelphia: Elsevier, p. 447-452

Research output: Chapter in Book/Conference paperChapter

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Renal Sympathetic Denervation

Schlaich, M., 2015, Chronic Kidney Disease and Hypertension. Weir, M. R. & Lerma, E. V. (eds.). New York: Humana Press, p. 69-81

Research output: Chapter in Book/Conference paperChapter

The potential role of catheter-based renal sympathetic denervation in chronic and end-stage kidney disease

Schlaich, M. P. & Sata, Y., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. Springer-Verlag London Ltd., p. 181-189 9 p.

Research output: Chapter in Book/Conference paperChapter

The role of renal nerves in cardiorenal syndrome in heart failure

Katholi, R., Sobotka, P. A., Schlaich, M. & Krum, H., 2012, The Cardiorenal Syndrome: A Clinician’s Guide to Pathophsyiology and Management. Heywood, J. T. & Burnett Jr, J. C. (eds.). Cardiotext Publishing

Research output: Chapter in Book/Conference paperChapter

Comment/debate

Angiotensin receptor blockade in diabetic women of childbearing potential: An acceptable risk?

Schlaich, M. P., Jun 2011, In : Diabetologia. 54, 6, p. 1267-1269 3 p.

Research output: Contribution to journalComment/debate

Open Access
1 Citation (Scopus)

Biomarkers for the prediction of blood pressure response to renal denervation: A long way to go

Schlaich, M., 2014, In : Hypertension. 63, 5, p. 907-908 2 p.

Research output: Contribution to journalComment/debate

Open Access
4 Citations (Scopus)

Central arteriovenous anastomosis in resistant hypertension?

Schlaich, M. & Hering, D., 2015, In : The Lancet. 385, 9978, p. 1596-1597 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)