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  • Hugh Barrett

Ldl-cholesterol, ApoB100 Kinetics and Atherosclerosis in Ldlr-deficient Yucatan Minipigs: A New Model for Familial Hypercholesterolemia

Telford, D. E., Burke, A. C., Sutherland, B. G., Sawyez, C. G., Edwards, J. Y., Barrett, P. H., Newton, R. S. & Huff, M. W., May 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, Supplement 1, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

8 Downloads (Pure)
Article
1 Citation (Scopus)

A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production

Anthanont, P., Polisecki, E. Y., Asztalos, B. F., Diffenderfer, M. R., Barrett, H., Millar, J. S., Billheimer, J. T., Cuchel, M., Rader, D. J. & Schaefer, E. J., 2014, In : Atherosclerosis. 235, 2, p. 470-476

Research output: Contribution to journalArticle

9 Citations (Scopus)

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity

Verges, B., Adiels, M., Borén, J., Barrett, H., Watts, G., Chan, D., Duvillard, L., Soderlund, S., Matikainen, N., Kahri, J., Lundbom, N., Lundbom, J., Hakkarainen, N., Aho, S., Simoneau-Robin, I. & Taskinen, M. R., 1 Apr 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1398-1406 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
8 Citations (Scopus)

Apolipoprotein B-100 and ApoA-II kinetics as determinants of cellular cholesterol efflux

Chan, D., Hoang, A., Barrett, H., Wong, A. T. Y., Nestel, P. J., Sviridov, D. & Watts, G., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, p. E1658-E1666

Research output: Contribution to journalArticle

16 Citations (Scopus)

Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations

Ooi, E., Russell, B. S., Olson, E., Sun, S. Z., Diffenderfer, M. R., Lichtenstein, A. H., Keilson, L., Barrett, H., Schaefer, E. J. & Sprecher, D. L., 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, p. 459-466

Research output: Contribution to journalArticle

Open Access
14 Citations (Scopus)
Open Access
File
6 Citations (Scopus)
252 Downloads (Pure)
Open Access
File
7 Citations (Scopus)
313 Downloads (Pure)
7 Citations (Scopus)

Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient (LDLR+/− and LDLR−/−) Yucatan Miniature Pigs

Burke, A. C., Telford, D. E., Sutherland, B. G., Edwards, J. Y., Sawyez, C. G., Barrett, P. H. R., Newton, R. S., Pickering, J. G. & Huff, M. W., 15 Feb 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 5, p. 1178-1190

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
435 Downloads (Pure)
Open Access
10 Citations (Scopus)

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

Watts, G. F., Chan, D. C., Somaratne, R., Wasserman, S. M., Scott, R., Marcovina, S. M. & Barrett, P. H. R., 14 Jul 2018, In : European Heart Journal. 39, 27, p. 2577-2585 9 p.

Research output: Contribution to journalArticle

Differential Effects of Estrogen and Progestin on Apolipoprotein B100 and B48 Kinetics in Postmenopausal Women

Lamon-Fava, S., Diffenderfer, M. R., Barrett, P. H. R., Wan, W. Y., Postfai, B., Nartsupha, C., Dolnikowski, G. G. & Schaefer, E. J., 1 Feb 2018, In : Lipids. 53, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a)

Diffenderfer, MR., Lamon-Fava, S., Marcovina, SM., Barrett, H., Dolikowski, GG., Berglund, L. & Schaefer, EJ., 2016, In : METABOLISM-CLINICAL AND EXPERIMENTAL. 65, 4, p. 381-390

Research output: Contribution to journalArticle

26 Citations (Scopus)

Dose-dependent effects of rosuvastatin on the plasma sphingolipidome and phospholipidome in the metabolic syndrome

Ng, T. W., Ooi, E., Watts, G., Chan, D., Weir, J. M., Meikle, P. J. & Barrett, H., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 11, p. E2335-E2340

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome

Ooi, E., Ng, T. W., Watts, G., Chan, D. & Barrett, H., 2012, In : Journal of Lipid Research. 53, p. 2443-2449

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
Open Access
24 Citations (Scopus)

Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetes

Pang, J., Chan, D., Hamilton, S., Tenneti, V. S., Watts, G. & Barrett, H., 11 Mar 2016, In : Diabetes, Obesity and Metabolism. 18, 4, p. 384-391 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
297 Downloads (Pure)
Open Access
File
12 Citations (Scopus)
334 Downloads (Pure)
Open Access
File
17 Citations (Scopus)
261 Downloads (Pure)
Open Access
File
34 Citations (Scopus)
310 Downloads (Pure)

Effects of therapeutic lifestyle change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects

Ooi, E., Lichtenstein, A. H., Millar, J. S., Diffenderfer, M. R., Lamon-Fava, S., Rasmussen, H., Welty, F. K., Barrett, H. & Schaefer, E. J., Sep 2012, In : Journal of Lipid Research. 53, p. 1958-1967

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Factorial effects of evolocumab and atorvastatin on lipoprotein metabolism

Watts, G. F., Chan, D. C., Dent, R., Somaratne, R., Wasserman, S. M., Scott, R., Burrows, S. & Barrett, P. H. R., 24 Jan 2017, In : Circulation. 135, 4, p. 338-351 14 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
1 Citation (Scopus)
Open Access
2 Citations (Scopus)
29 Citations (Scopus)

Interrelationships between the kinetics of VLDL subspecies and hdl catabolism in abdominal obesity: A multicenter tracer kinetic study

Vergès, B. L., Adiels, M., Borén, J. B., Barrett, H., Watts, G., Chan, D., Duvillard, L., Söderlund, S., Matikainen, N., Kahri, J., Robin, I. & Taskinen, M. R., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 11, p. 4281-4290

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Kinetic and related determinants of plasma triglyceride concentration in abdominal obesity: Multicenter tracer kinetic study

Borén, J., Watts, G. F., Adiels, M., Söderlund, S., Chan, D. C., Hakkarainen, A., Lundbom, N., Matikainen, N., Kahri, J., Vergès, B., Barrett, H. & Taskinen, M. R., Oct 2015, In : Arteriosclerosis, thrombosis, and vascular biology. 35, 10, p. 2218-2224 7 p.

Research output: Contribution to journalArticle

Open Access
File
35 Citations (Scopus)
494 Downloads (Pure)
4 Citations (Scopus)
2 Citations (Scopus)
Open Access
7 Citations (Scopus)

Lipoprotein metabolism in an apoB-80 familial hypobetalipoproteinemia heterozygote

Hooper, A., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, K. G., Barrett, H., Van Bockxmeer, F. & Burnett, J., Jun 2016, In : Clinical Biochemistry. 49, 9, p. 720-722

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
241 Downloads (Pure)

Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia.

Hooper, A., Heeks, L., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, P., Barrett, H., Van Bockxmeer, F. & Burnett, J., Nov 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 11, p. E1484-E1490 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
156 Downloads (Pure)

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

Hodson, L., Banerjee, R., Rial, B., Arlt, W., Adiels, M., Boren, J., Marionou, K., Fisher, C., Mostad, I. L., Stratton, I. M., Barrett, H., Chan, D., Watts, G., Harnden, K., Karpe, F. & Fielding, B. A., 2015, In : Journal of the American Heart Association. 4, 10, p. 1-45

Research output: Contribution to journalArticle

Open Access
27 Citations (Scopus)

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin

Thongtang, N., Diffenderfer, M. R., Ooi, E. M. M., Barrett, P. H. R., Turner, S. M., Le, N-A., Brown, W. V. & Schaefer, E. J., Jul 2017, In : Journal of Lipid Research. 58, 7, p. 1315-1324 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
6 Citations (Scopus)

Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men

Wong, A. T. Y., Chan, D., Ooi, E., Ng, T. W., Watts, G. & Barrett, H., Jul 2013, In : Clinical Science. 125, 1, p. 45-51

Research output: Contribution to journalArticle

12 Citations (Scopus)

Omega-3 Fatty acids-3 fatty acid ethyl esters diminish postprandial lipemia in familial hypercholesterolemia

Chan, D., Pang, J., Barrett, H., Sullivan, D. R., Burnett, J., Van Bockxmeer, F. & Watts, G., Oct 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 10, p. 3732-3739 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
217 Downloads (Pure)

PCSK9 Inhibition with alirocumab increases the catabolism of lipoprotein(a) particles in statin-treated patients with elevated lipoprotein(a)

Watts, G. F., Chan, D. C., Pang, J., Ma, L., Ying, Q., Aggarwal, S., Marcovina, S. M. & Barrett, P. H. R., Jun 2020, In : Metabolism. 107, 154221.

Research output: Contribution to journalArticle

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD

Mardinoglu, A., Bjornson, E., Zhang, C., Klevstig, M., Söderlund, S., Ståhlman, M., Adiels, M., Hakkarainen, A., Lundbom, N., Kilicarslan, M., Hallström, B. M., Lundbom, J., Vergès, B., Barrett, P. H. R., Watts, G. F., Serlie, M. J., Nielsen, J., Uhlén, M., Smith, U., Marschall, H. U. & 2 others, Taskinen, M. R. & Boren, J., 1 Mar 2017, In : Molecular Systems Biology. 13, 3, 916.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)
Open Access
File
22 Citations (Scopus)
280 Downloads (Pure)

Plasma apolipoprotein C-III metabolism in patients with chronic kidney disease

Ooi, E., Chan, D. T., Watts, G., Chan, D., Ng, T. K., Dogra, G., Irish, A. & Barrett, H., 2011, In : Journal of Lipid Research. 52, p. 794-800

Research output: Contribution to journalArticle

Open Access
37 Citations (Scopus)
Open Access
File
27 Citations (Scopus)
370 Downloads (Pure)

Postprandial effects of a high salt meal on serum sodium, arterial stiffness, markers of nitric oxide production and markers of endothelial function

Dickinson, K. M., Clifton, P. M., Burrell, L. M., Barrett, H. & Keogh, J. B., Jan 2014, In : Atherosclerosis. 232, 1, p. 211-216

Research output: Contribution to journalArticle

26 Citations (Scopus)

Rosuvastatin enhances the catabolism of LDL apoB-100 in subjects with combined hyperlipidemia in a dose dependent manner

Le, N. A., Diffenderfer, M. R., Thongtang, N., Ooi, E., Barrett, H., Horvath, K. V., Dolnikowski, G. G., Asztalos, B. F., Schaefer, E. J. & Brown, W. V., 2015, In : Lipids. 50, 5, p. 447-458

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access
17 Citations (Scopus)