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  • Hugh Barrett

Ldl-cholesterol, ApoB100 Kinetics and Atherosclerosis in Ldlr-deficient Yucatan Minipigs: A New Model for Familial Hypercholesterolemia

Telford, D. E., Burke, A. C., Sutherland, B. G., Sawyez, C. G., Edwards, J. Y., Barrett, P. H., Newton, R. S. & Huff, M. W., May 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, Supplement 1, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

8 Downloads (Pure)
Article

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity

Verges, B., Adiels, M., Borén, J., Barrett, H., Watts, G., Chan, D., Duvillard, L., Soderlund, S., Matikainen, N., Kahri, J., Lundbom, N., Lundbom, J., Hakkarainen, N., Aho, S., Simoneau-Robin, I. & Taskinen, M. R., 1 Apr 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1398-1406 9 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Apolipoprotein B-100 and ApoA-II kinetics as determinants of cellular cholesterol efflux

Chan, D., Hoang, A., Barrett, H., Wong, A. T. Y., Nestel, P. J., Sviridov, D. & Watts, G., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, p. E1658-E1666

Research output: Contribution to journalArticle

16 Citations (Scopus)

Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations

Ooi, E., Russell, B. S., Olson, E., Sun, S. Z., Diffenderfer, M. R., Lichtenstein, A. H., Keilson, L., Barrett, H., Schaefer, E. J. & Sprecher, D. L., 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, p. 459-466

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Association of apolipoprotein M with high-density lipoprotein kinetics in overweight-obese men

Ooi, E., Watts, G., Chan, D., Nielsen, L. B., Plomgaard, P., Dahlback, B. & Barrett, H., 2010, In : Atherosclerosis. 210, p. 326-330

Research output: Contribution to journalArticle

18 Citations (Scopus)
Open Access
File
7 Citations (Scopus)
282 Downloads (Pure)

Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient (LDLR+/− and LDLR−/−) Yucatan Miniature Pigs

Burke, A. C., Telford, D. E., Sutherland, B. G., Edwards, J. Y., Sawyez, C. G., Barrett, P. H. R., Newton, R. S., Pickering, J. G. & Huff, M. W., 15 Feb 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 5, p. 1178-1190

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
418 Downloads (Pure)
Open Access
9 Citations (Scopus)

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

Watts, G. F., Chan, D. C., Somaratne, R., Wasserman, S. M., Scott, R., Marcovina, S. M. & Barrett, P. H. R., 14 Jul 2018, In : European Heart Journal. 39, 27, p. 2577-2585 9 p.

Research output: Contribution to journalArticle

Differential Effects of Estrogen and Progestin on Apolipoprotein B100 and B48 Kinetics in Postmenopausal Women

Lamon-Fava, S., Diffenderfer, M. R., Barrett, P. H. R., Wan, W. Y., Postfai, B., Nartsupha, C., Dolnikowski, G. G. & Schaefer, E. J., 1 Feb 2018, In : Lipids. 53, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a)

Diffenderfer, MR., Lamon-Fava, S., Marcovina, SM., Barrett, H., Dolikowski, GG., Berglund, L. & Schaefer, EJ., 2016, In : METABOLISM-CLINICAL AND EXPERIMENTAL. 65, 4, p. 381-390

Research output: Contribution to journalArticle

25 Citations (Scopus)

Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects

Ooi, E., Janus, E. D., Grant, S. J., Sinclair, L. M. T. & Barrett, H., 2010, In : Journal of Lipid Research. 51, p. 2413-2421

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome

Ooi, E., Ng, T. W., Watts, G., Chan, D. & Barrett, H., 2012, In : Journal of Lipid Research. 53, p. 2443-2449

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetes

Pang, J., Chan, D., Hamilton, S., Tenneti, V. S., Watts, G. & Barrett, H., 11 Mar 2016, In : Diabetes, Obesity and Metabolism. 18, 4, p. 384-391 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
286 Downloads (Pure)
Open Access
File
12 Citations (Scopus)
323 Downloads (Pure)

Effect of weight loss on HDL-apoA-II kinetics in the metabolic syndrome

Ng, T. W., Chan, D., Barrett, H. & Watts, G., 2010, In : Clinical Science. 118, p. 79-85

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)
Open Access
File
34 Citations (Scopus)
278 Downloads (Pure)

Effects of therapeutic lifestyle change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects

Ooi, E., Lichtenstein, A. H., Millar, J. S., Diffenderfer, M. R., Lamon-Fava, S., Rasmussen, H., Welty, F. K., Barrett, H. & Schaefer, E. J., Sep 2012, In : Journal of Lipid Research. 53, p. 1958-1967

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Factorial effects of evolocumab and atorvastatin on lipoprotein metabolism

Watts, G. F., Chan, D. C., Dent, R., Somaratne, R., Wasserman, S. M., Scott, R., Burrows, S. & Barrett, P. H. R., 24 Jan 2017, In : Circulation. 135, 4, p. 338-351 14 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
1 Citation (Scopus)

Genetic determinants of apolipoprotein B-100 kinetics

Ng, T. W., Ooi, E., Watts, G., Chan, D. & Barrett, H., 2010, In : Current Opinion in Lipidology. 21, p. 141-147

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
2 Citations (Scopus)

Influence of Simvastatin on apoB-100 Secretion in Non-Obese subjects with Mild Hypercholesterolemia

Berthold, H. K., Mertens, J., Birnbaum, J., Bramswig, S., Sudhop, T., Barrett, H., Von Bergmann, K. & Gouni-Berthold, I., 2010, In : Lipids. 45, 1, p. 491-500

Research output: Contribution to journalArticle

3 Citations (Scopus)
28 Citations (Scopus)

Kinetic and related determinants of plasma triglyceride concentration in abdominal obesity: Multicenter tracer kinetic study

Borén, J., Watts, G. F., Adiels, M., Söderlund, S., Chan, D. C., Hakkarainen, A., Lundbom, N., Matikainen, N., Kahri, J., Vergès, B., Barrett, H. & Taskinen, M. R., Oct 2015, In : Arteriosclerosis, thrombosis, and vascular biology. 35, 10, p. 2218-2224 7 p.

Research output: Contribution to journalArticle

Open Access
File
34 Citations (Scopus)
483 Downloads (Pure)
4 Citations (Scopus)
2 Citations (Scopus)
Open Access
7 Citations (Scopus)

Lipoprotein metabolism in an apoB-80 familial hypobetalipoproteinemia heterozygote

Hooper, A., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, K. G., Barrett, H., Van Bockxmeer, F. & Burnett, J., Jun 2016, In : Clinical Biochemistry. 49, 9, p. 720-722

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
232 Downloads (Pure)

Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia.

Hooper, A., Heeks, L., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, P., Barrett, H., Van Bockxmeer, F. & Burnett, J., Nov 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 11, p. E1484-E1490 7 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
155 Downloads (Pure)

Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics

Tomazela, D. M., Patterson, B. W., Hanson, E., Spence, K. L., Kanion, T. B., Salinger, D. H., Vicini, P., Barrett, H., Heins, H. B., Cole, F. S., Hamvas, A. & Maccoss, M. J., 2010, In : Analytical Chemistry. 82, 6, p. 2561-2567

Research output: Contribution to journalArticle

18 Citations (Scopus)

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

Hodson, L., Banerjee, R., Rial, B., Arlt, W., Adiels, M., Boren, J., Marionou, K., Fisher, C., Mostad, I. L., Stratton, I. M., Barrett, H., Chan, D., Watts, G., Harnden, K., Karpe, F. & Fielding, B. A., 2015, In : Journal of the American Heart Association. 4, 10, p. 1-45

Research output: Contribution to journalArticle

Open Access
25 Citations (Scopus)

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin

Thongtang, N., Diffenderfer, M. R., Ooi, E. M. M., Barrett, P. H. R., Turner, S. M., Le, N-A., Brown, W. V. & Schaefer, E. J., Jul 2017, In : Journal of Lipid Research. 58, 7, p. 1315-1324 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
6 Citations (Scopus)

Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men

Wong, A. T. Y., Chan, D., Ooi, E., Ng, T. W., Watts, G. & Barrett, H., Jul 2013, In : Clinical Science. 125, 1, p. 45-51

Research output: Contribution to journalArticle

11 Citations (Scopus)

Omega-3 Fatty acids-3 fatty acid ethyl esters diminish postprandial lipemia in familial hypercholesterolemia

Chan, D., Pang, J., Barrett, H., Sullivan, D. R., Burnett, J., Van Bockxmeer, F. & Watts, G., Oct 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 10, p. 3732-3739 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
214 Downloads (Pure)

Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD

Mardinoglu, A., Bjornson, E., Zhang, C., Klevstig, M., Söderlund, S., Ståhlman, M., Adiels, M., Hakkarainen, A., Lundbom, N., Kilicarslan, M., Hallström, B. M., Lundbom, J., Vergès, B., Barrett, P. H. R., Watts, G. F., Serlie, M. J., Nielsen, J., Uhlén, M., Smith, U., Marschall, H. U. & 2 others, Taskinen, M. R. & Boren, J., 1 Mar 2017, In : Molecular Systems Biology. 13, 3, 916.

Research output: Contribution to journalArticle

Open Access
42 Citations (Scopus)
Open Access
File
27 Citations (Scopus)
363 Downloads (Pure)

Rosuvastatin enhances the catabolism of LDL apoB-100 in subjects with combined hyperlipidemia in a dose dependent manner

Le, N. A., Diffenderfer, M. R., Thongtang, N., Ooi, E., Barrett, H., Horvath, K. V., Dolnikowski, G. G., Asztalos, B. F., Schaefer, E. J. & Brown, W. V., 2015, In : Lipids. 50, 5, p. 447-458

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access
17 Citations (Scopus)

Tamoxifen reduces hepatic VLDL production and GH secretion in women: A possible mechanism for steatosis development

Birzniece, V., Barrett, P. H. R. & Ho, K. K. Y., 1 Aug 2017, In : European Journal of Endocrinology. 177, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
191 Downloads (Pure)

The effect of fenofibrate on HDL cholesterol and HDL particle concentration in postmenopausal women on tibolone therapy

Stuckey, B., Barrett, H., Wagner, J. M., Hampton, R. A., Chan, D., Brown, S. J. & Watts, G., 2010, In : Clinical Endocrinology. 73, p. 497-501

Research output: Contribution to journalArticle

1 Citation (Scopus)
31 Citations (Scopus)

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III

Ooi, E. M., Chan, D. C., Hodson, L., Adiels, M., Boren, J., Karpe, F., Fielding, B. A., Watts, G. F. & Barrett, H. H. R., 2016, In : European Journal of Clinical Investigation. 46, 8, p. 730-736 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)