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  • Markus Schlaich
Article

Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial

Stoiber, L., Mahfoud, F., Zamani, S. M., Lapinskas, T., Böhm, M., Ewen, S., Kulenthiran, S., Schlaich, M. P., Esler, M. D., Hammer, T., Stensæth, K. H., Pieske, B., Dreysse, S., Fleck, E., Kühne, T., Kelm, M., Stawowy, P. & Kelle, S., 1 Aug 2018, In : Clinical Research in Cardiology. 107, 8, p. 642-652 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
1 Citation (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2

Matthews, V. B., Elliot, R. H., Rudnicka, C., Hricova, J., Herat, L. & Schlaich, M. P., 1 Oct 2017, In : Journal of Hypertension. 35, 10, p. 2059–2068

Research output: Contribution to journalArticle

35 Citations (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Booth, L. C., Schlaich, M. P., Nishi, E. E., Yao, S. T., Xu, J., Ramchandra, R., Lambert, G. W. & May, C. N., 1 Jul 2015, In : International Journal of Cardiology. 190, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
48 Downloads (Pure)

Single-unit muscle sympathetic nervous activity and its relation to cardiac noradrenaline spillover

Lambert, E. A., Schlaich, M. P., Dawood, T., Sari, C., Chopra, R., Barton, D. A., Kaye, D. M., Elam, M., Esler, M. D. & Lambert, G. W., May 2011, In : Journal of Physiology. 589, 10, p. 2597-2605 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Soluble vascular endothelial growth factor receptor-1 is reduced in patients with resistant hypertension after renal denervation

Eikelis, N., Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Sata, Y., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : Journal of Human Hypertension. 31, 4, p. 248-252 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
246 Citations (Scopus)

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients

Zaldivia, M. T. K., Hering, D., Marusic, P., Sata, Y., Lee, R., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Flierl, U., Wang, X., Drummond, G. R., Walton, A., Gardiner, E. E., Andrews, R. K., Schlaich, M. P. & Peter, K., Jan 2019, In : Cardiovascular Research. 116, 1, p. 202-210

Research output: Contribution to journalArticle

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation

Singh, R. R., McArdle, Z. M., Iudica, M., Easton, L. K., Booth, L. C., May, C. N., Parkington, H. C., Lombardo, P., Head, G. A., Lambert, G., Moritz, K. M., Schlaich, M. P. & Denton, K. M., Mar 2019, In : Hypertension. 73, 3, p. 718-727 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Krum, H., Narkiewicz, K., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 2014, In : Hypertension. 64, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Open Access
98 Citations (Scopus)

Sympathetic activation and endothelial dysfunction in polycystic ovary syndrome are not explained by either obesity or insulin resistance

Lambert, E. A., Teede, H., Sari, C. I., Jona, E., Shorakae, S., Woodington, K., Hemmes, R., Eikelis, N., Straznicky, N. E., De Courten, B., Dixon, J. B., Schlaich, M. P. & Lambert, G. W., Dec 2015, In : Clinical Endocrinology. 83, 6, p. 812-819 8 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

Sympathetic and vascular dysfunction in adult patients with Fontan circulation

Lambert, E., D'Udekem, Y., Cheung, M., Sari, C. I., Inman, J., Ahimastos, A., Eikelis, N., Pathak, A., King, I., Grigg, L., Schlaich, M. & Lambert, G., 20 Aug 2013, In : International Journal of Cardiology. 167, 4, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

25 Citations (Scopus)

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
135 Citations (Scopus)

Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects

Straznicky, N. E., Lambert, E. A., Nestel, P. J., McGrane, M. T., Dawood, T., Schlaich, M. P., Masuo, K., Eikelis, N., De Courten, B., Mariani, J. A., Esler, M. D., Socratous, F., Chopra, R., Sari, C. I., Paul, E. & Lambert, G. W., 2010, In : Diabetes. 59, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

Open Access
68 Citations (Scopus)

Sympathetic Response and Outcomes Following Renal Denervation in Patients With Chronic Heart Failure: 12-Month Outcomes From the Symplicity HF Feasibility Study

Hopper, I., Gronda, E., Hoppe, U. C., Rundqvist, B., Marwick, T. H., Shetty, S., Hayward, C., Lambert, T., Hering, D., Esler, M., Schlaich, M., Walton, A., Airoldi, F., Brandt, M. C., Cohen, S. A., Reiters, P. & Krum, H., 1 Sep 2017, In : Journal of Cardiac Failure. 23, 9, p. 702-707 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The effect of renal denervation on plasma adipokine profile in patients with treatment resistant hypertension

Eikelis, N., Hering, D., Marusic, P., Duval, J., Hammond, L. J., Walton, A. S., Lambert, E. A., Esler, M. D., Lambert, G. W. & Schlaich, M. P., 30 May 2017, In : Frontiers in Physiology. 8, MAY, 369.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The effects of weight loss versus weight loss maintenance on sympathetic nervous system activity and metabolic syndrome components

Straznicky, N. E., Grima, M. T., Eikelis, N., Nestel, P. J., Dawood, T., Schlaich, M. P., Chopra, R., Masuo, K., Esler, M. D., Sari, C. I., Lambert, G. W. & Lambert, E. A., Mar 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 3

Research output: Contribution to journalArticle

Open Access
71 Citations (Scopus)

The metalloproteinase ADAM28 promotes metabolic dysfunction in mice

Herat, L., Rudnicka, C., Okada, Y., Mochizuki, S., Schlaich, M. & Matthews, V., 21 Apr 2017, In : International Journal of Molecular Sciences. 18, 4, 12 p., 884.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Karapanagiotidis, S., Wong, C., Eikelis, N., Richards, K. L., Lee, G., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P. & Lambert, E. A., 1 Feb 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 2

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
Open Access
File
5 Citations (Scopus)
376 Downloads (Pure)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

5 Citations (Scopus)

Type 2 diabetes strengthens the association between pulse pressure and chronic kidney disease: The AusDiab study

Van Den Hurk, K., Magliano, D. J., Alssema, M., Schlaich, M. P., Atkins, R. C., Reutens, A. T., Nijpels, G., Dekker, J. M. & Shaw, J. E., May 2011, In : Journal of Hypertension. 29, 5, p. 953-960 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
Book

Renal denervation: A new approach to treatment of resistant hypertension

Heuser, R. R. (ed.), Schlaich, M. (ed.) & Sievert, H. (ed.), 2015, New York: Springer-Verlag London Ltd. 201 p.

Research output: Book/ReportBook

Chapter

Device-based approaches to target renal sympathetic nerves for hypertension

Schlaich, M. & Esler, M. D., 2016, Surgery of the Autonomic Nervous System. Hyam, J. A., Pereira, E. A. C. & Green, A. L. (eds.). Oxford University Press

Research output: Chapter in Book/Conference paperChapter

Devices for Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2013, Hypertension: A Companion to Braunwald's Heart Disease: Second Edition. Elsevier, p. 230-235 6 p.

Research output: Chapter in Book/Conference paperChapter

Heart/Kidney interactions

Schlaich, M., 19 Dec 2018, The ESC Textbook of Cardiovascular Medicine. Camm, A. J., Lüscher, T. F., Maurer, G. & Serruys, P. W. (eds.). 3 ed. Oxford University Press

Research output: Chapter in Book/Conference paperChapter

Interventional Treatments for Resistant Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2014, Comprehensive Clinical Nephrology . Johnson, R., Feehally, J. & Floege, J. (eds.). 5 ed. Philadelphia: Elsevier, p. 447-452

Research output: Chapter in Book/Conference paperChapter

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Renal denervation: Current opinions and practice

Schlaich, M. P., 31 Jul 2017, Cardio-Nephrology: Confluence of the Heart and Kidney in Clinical Practice. USA: Springer International Publishing AG, p. 419-426 8 p.

Research output: Chapter in Book/Conference paperChapter

Renal Sympathetic Denervation

Schlaich, M., 2015, Chronic Kidney Disease and Hypertension. Weir, M. R. & Lerma, E. V. (eds.). New York: Humana Press, p. 69-81

Research output: Chapter in Book/Conference paperChapter

The potential role of catheter-based renal sympathetic denervation in chronic and end-stage kidney disease

Schlaich, M. P. & Sata, Y., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. Springer-Verlag London Ltd., p. 181-189 9 p.

Research output: Chapter in Book/Conference paperChapter

Comment/debate

Angiotensin receptor blockade in diabetic women of childbearing potential: An acceptable risk?

Schlaich, M. P., Jun 2011, In : Diabetologia. 54, 6, p. 1267-1269 3 p.

Research output: Contribution to journalComment/debate

Open Access
1 Citation (Scopus)

Biomarkers for the prediction of blood pressure response to renal denervation: A long way to go

Schlaich, M., 2014, In : Hypertension. 63, 5, p. 907-908 2 p.

Research output: Contribution to journalComment/debate

Open Access
4 Citations (Scopus)

Central arteriovenous anastomosis in resistant hypertension?

Schlaich, M. & Hering, D., 2015, In : The Lancet. 385, 9978, p. 1596-1597 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)
1 Citation (Scopus)

CrossTalk opposing view: Which technique for controlling resistant hypertension? Renal nerve ablation

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, p. 3937-3940 4 p.

Research output: Contribution to journalComment/debate

Open Access
5 Citations (Scopus)

Diuretics and skin cancer: Should a common prescription come with advice to avoid sun exposure?

Schlaich, M. P., Nolde, J., Carnagarin, R. & Kiuchi, M. G., 1 Oct 2019, In : Journal of Hypertension. 37, 10, p. 1961-1962 2 p.

Research output: Contribution to journalComment/debate

Metabolic syndrome: A sympathetic disease?

Schlaich, M., Straznicky, N., Lambert, E. & Lambert, G., 1 Feb 2015, In : The Lancet Diabetes and Endocrinology. 3, 2, p. 148-157 10 p.

Research output: Contribution to journalComment/debate

48 Citations (Scopus)

Rebuttal from Esler, Lambert, and Schlaich.

Esler, M., Lambert, E. & Schlaich, M., 2010, In : Journal of applied physiology (Bethesda, Md. : 1985). 109, 6, p. 2000-2001 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Rebuttal from Markus P. Schlaich, Yusuke Sata and Murray D. Esler

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Renal denervation in less severe forms of (resistant) hypertension—Quo vadis?

Schlaich, M. P., Hering, D. & Sata, Y., 1 Apr 2017, In : Journal of Clinical Hypertension. 19, 4, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

Suitability for catheter-based renal denervation-lessons from 'super-responders'

Schlaich, M. P., Carnagarin, R., Ho, J. K. & Matthews, V. B., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1475-1476 2 p.

Research output: Contribution to journalComment/debate

Sympathoexcitation in calcineurin inhibitor-induced hypertension: Villain or innocent bystander?

Schlaich, M. P. & Grassi, G., Sep 2010, In : Journal of Hypertension. 28, 9, p. 1809-1810 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)