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Ldl-cholesterol, ApoB100 Kinetics and Atherosclerosis in Ldlr-deficient Yucatan Minipigs: A New Model for Familial Hypercholesterolemia

Telford, D. E., Burke, A. C., Sutherland, B. G., Sawyez, C. G., Edwards, J. Y., Barrett, P. H., Newton, R. S. & Huff, M. W., May 2017, In : Arteriosclerosis, thrombosis, and vascular biology. 37, Supplement 1, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Article
Blood Platelets
Exercise
Platelet Activation
Brachial Artery
Acute Coronary Syndrome
9 Citations (Scopus)

A novel ApoA-I truncation (ApoA-IMytilene) associated with decreased ApoA-I production

Anthanont, P., Polisecki, E. Y., Asztalos, B. F., Diffenderfer, M. R., Barrett, H., Millar, J. S., Billheimer, J. T., Cuchel, M., Rader, D. J. & Schaefer, E. J., 2014, In : Atherosclerosis. 235, 2, p. 470-476

Research output: Contribution to journalArticle

Apolipoproteins A
Apolipoprotein A-I
Cholesterol
HDL Cholesterol
Arcus Senilis
1 Citation (Scopus)

ApoA-II HDL Catabolism and Its Relationships With the Kinetics of ApoA-I HDL and of VLDL1, in Abdominal Obesity

Verges, B., Adiels, M., Borén, J., Barrett, H., Watts, G., Chan, D., Duvillard, L., Soderlund, S., Matikainen, N., Kahri, J., Lundbom, N., Lundbom, J., Hakkarainen, N., Aho, S., Simoneau-Robin, I. & Taskinen, M. R., 1 Apr 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 4, p. 1398-1406 9 p.

Research output: Contribution to journalArticle

Open Access
Apolipoprotein A-II
Abdominal Obesity
Apolipoprotein A-I
HDL Lipoproteins
Kinetics
Apoprotein(a)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Plasmas
Kinetics
8 Citations (Scopus)
16 Citations (Scopus)

Apolipoprotein B-100 and ApoA-II kinetics as determinants of cellular cholesterol efflux

Chan, D., Hoang, A., Barrett, H., Wong, A. T. Y., Nestel, P. J., Sviridov, D. & Watts, G., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, p. E1658-E1666

Research output: Contribution to journalArticle

11 Citations (Scopus)

Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations

Ooi, E., Russell, B. S., Olson, E., Sun, S. Z., Diffenderfer, M. R., Lichtenstein, A. H., Keilson, L., Barrett, H., Schaefer, E. J. & Sprecher, D. L., 2012, In : Arteriosclerosis, thrombosis, and vascular biology. 32, p. 459-466

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
194 Downloads (Pure)
Open Access
File
Apolipoprotein B-100
VLDL Lipoproteins
Weight Loss
Skeletal Muscle
Obesity
18 Citations (Scopus)

Association of apolipoprotein M with high-density lipoprotein kinetics in overweight-obese men

Ooi, E., Watts, G., Chan, D., Nielsen, L. B., Plomgaard, P., Dahlback, B. & Barrett, H., 2010, In : Atherosclerosis. 210, p. 326-330

Research output: Contribution to journalArticle

7 Citations (Scopus)
191 Downloads (Pure)
Open Access
File
Apolipoprotein B-100
Sphingomyelins
VLDL Lipoproteins
Ceramides
Plasmas
5 Citations (Scopus)
Omega-3 Fatty Acids
Esters
Insulin
Placebos
very low density lipoprotein triglyceride
6 Citations (Scopus)
336 Downloads (Pure)

Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient (LDLR+/− and LDLR−/−) Yucatan Miniature Pigs

Burke, A. C., Telford, D. E., Sutherland, B. G., Edwards, J. Y., Sawyez, C. G., Barrett, P. H. R., Newton, R. S., Pickering, J. G. & Huff, M. W., 15 Feb 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 5, p. 1178-1190

Research output: Contribution to journalArticle

Open Access
File
LDL Lipoproteins
LDL Cholesterol
Atherosclerosis
Swine
Cholesterol
7 Citations (Scopus)
Open Access
Apolipoprotein B-48
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoproteins
Triglycerides
Apolipoprotein B-100
44 Citations (Scopus)

Controlled study of the effect of proprotein convertase subtilisin-kexin type 9 inhibition with evolocumab on lipoprotein(a) particle kinetics

Watts, G. F., Chan, D. C., Somaratne, R., Wasserman, S. M., Scott, R., Marcovina, S. M. & Barrett, P. H. R., 14 Jul 2018, In : European Heart Journal. 39, 27, p. 2577-2585 9 p.

Research output: Contribution to journalArticle

Lipoprotein(a)
Apoprotein(a)
AMG 145
Proprotein Convertase 9
Apolipoproteins B
1 Citation (Scopus)

Differential Effects of Estrogen and Progestin on Apolipoprotein B100 and B48 Kinetics in Postmenopausal Women

Lamon-Fava, S., Diffenderfer, M. R., Barrett, P. H. R., Wan, W. Y., Postfai, B., Nartsupha, C., Dolnikowski, G. G. & Schaefer, E. J., 1 Feb 2018, In : Lipids. 53, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

Apolipoprotein B-48
Apolipoproteins
Progestins
Lipoproteins
Estrogens
23 Citations (Scopus)

Distinct metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein(a)

Diffenderfer, MR., Lamon-Fava, S., Marcovina, SM., Barrett, H., Dolikowski, GG., Berglund, L. & Schaefer, EJ., 2016, In : METABOLISM-CLINICAL AND EXPERIMENTAL. 65, 4, p. 381-390

Research output: Contribution to journalArticle

15 Citations (Scopus)

Dose-dependent effects of rosuvastatin on the plasma sphingolipidome and phospholipidome in the metabolic syndrome

Ng, T. W., Ooi, E., Watts, G., Chan, D., Weir, J. M., Meikle, P. J. & Barrett, H., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 11, p. E2335-E2340

Research output: Contribution to journalArticle

Open Access
Sphingolipids
Allura Red AC Dye
Plasmas
Plasmalogens
Phosphatidylcholines
9 Citations (Scopus)

Effect of apolipoprotein E genotype on apolipoprotein B-100 metabolism in normolipidemic and hyperlipidemic subjects

Ooi, E., Janus, E. D., Grant, S. J., Sinclair, L. M. T. & Barrett, H., 2010, In : Journal of Lipid Research. 51, p. 2413-2421

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Effect of fenofibrate and atorvastatin on VLDL apoE metabolism in men with the metabolic syndrome

Ooi, E., Ng, T. W., Watts, G., Chan, D. & Barrett, H., 2012, In : Journal of Lipid Research. 53, p. 2443-2449

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)
Open Access
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Niacin
Apolipoprotein A-I
HDL Lipoproteins
Type 2 Diabetes Mellitus
7 Citations (Scopus)
238 Downloads (Pure)

Effect of niacin on triglyceride-rich lipoprotein apolipoprotein B-48 kinetics in statin-treated patients with type 2 diabetes

Pang, J., Chan, D., Hamilton, S., Tenneti, V. S., Watts, G. & Barrett, H., 11 Mar 2016, In : Diabetes, Obesity and Metabolism. 18, 4, p. 384-391 8 p.

Research output: Contribution to journalArticle

Open Access
File
Apolipoprotein B-48
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Niacin
Type 2 Diabetes Mellitus
Lipoproteins
10 Citations (Scopus)
241 Downloads (Pure)
Open Access
File
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hyperlipoproteinemia Type II
Elasticity
Omega-3 Fatty Acids
Blood Pressure
12 Citations (Scopus)

Effect of weight loss on HDL-apoA-II kinetics in the metabolic syndrome

Ng, T. W., Chan, D., Barrett, H. & Watts, G., 2010, In : Clinical Science. 118, p. 79-85

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)
197 Downloads (Pure)
Open Access
File
Apolipoprotein B-48
Reducing Diet
Nutrition
Esters
Fatty Acids
30 Citations (Scopus)
201 Downloads (Pure)
Open Access
File
Apolipoprotein B-100
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Niacin
VLDL Lipoproteins
22 Citations (Scopus)

Effects of therapeutic lifestyle change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects

Ooi, E., Lichtenstein, A. H., Millar, J. S., Diffenderfer, M. R., Lamon-Fava, S., Rasmussen, H., Welty, F. K., Barrett, H. & Schaefer, E. J., Sep 2012, In : Journal of Lipid Research. 53, p. 1958-1967

Research output: Contribution to journalArticle

Open Access
Therapeutic Uses
Nutrition
Apolipoprotein B-100
Metabolism
Fish
46 Citations (Scopus)

Factorial effects of evolocumab and atorvastatin on lipoprotein metabolism

Watts, G. F., Chan, D. C., Dent, R., Somaratne, R., Wasserman, S. M., Scott, R., Burrows, S. & Barrett, P. H. R., 24 Jan 2017, In : Circulation. 135, 4, p. 338-351 14 p.

Research output: Contribution to journalArticle

Apolipoprotein B-100
Lipoproteins
LDL Lipoproteins
IDL Lipoproteins
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Apolipoprotein B-100
Apoprotein(a)
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Lipoprotein(a)
Apolipoproteins B
3 Citations (Scopus)

Genetic determinants of apolipoprotein B-100 kinetics

Ng, T. W., Ooi, E., Watts, G., Chan, D. & Barrett, H., 2010, In : Current Opinion in Lipidology. 21, p. 141-147

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access
Platelet Activation
Exercise
Blood Platelets
Arachidonic Acid
Monocytes
3 Citations (Scopus)

Influence of Simvastatin on apoB-100 Secretion in Non-Obese subjects with Mild Hypercholesterolemia

Berthold, H. K., Mertens, J., Birnbaum, J., Bramswig, S., Sudhop, T., Barrett, H., Von Bergmann, K. & Gouni-Berthold, I., 2010, In : Lipids. 45, 1, p. 491-500

Research output: Contribution to journalArticle

27 Citations (Scopus)
Apolipoprotein B-48
Apolipoprotein C-III
Isotopes
Lipoproteins
Triglycerides
11 Citations (Scopus)

Interrelationships between the kinetics of VLDL subspecies and hdl catabolism in abdominal obesity: A multicenter tracer kinetic study

Vergès, B. L., Adiels, M., Borén, J. B., Barrett, H., Watts, G., Chan, D., Duvillard, L., Söderlund, S., Matikainen, N., Kahri, J., Robin, I. & Taskinen, M. R., 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 11, p. 4281-4290

Research output: Contribution to journalArticle

Open Access
Abdominal Obesity
VLDL Lipoproteins
Apolipoprotein A-I
Kinetics
Triglycerides
33 Citations (Scopus)
420 Downloads (Pure)

Kinetic and related determinants of plasma triglyceride concentration in abdominal obesity: Multicenter tracer kinetic study

Borén, J., Watts, G. F., Adiels, M., Söderlund, S., Chan, D. C., Hakkarainen, A., Lundbom, N., Matikainen, N., Kahri, J., Vergès, B., Barrett, H. & Taskinen, M. R., Oct 2015, In : Arteriosclerosis, thrombosis, and vascular biology. 35, 10, p. 2218-2224 7 p.

Research output: Contribution to journalArticle

Open Access
File
Abdominal Obesity
LDL Lipoproteins
Triglycerides
VLDL Lipoproteins
Apolipoproteins B
3 Citations (Scopus)
Apoprotein(a)
Lipoprotein(a)
Carotid Stenosis
Kringles
Coronary Artery Disease
1 Citation (Scopus)
Blood Component Removal
Lipoprotein(a)
Apolipoproteins B
LDL Lipoproteins
Metabolism
3 Citations (Scopus)
Open Access
Apoprotein(a)
Lipoprotein(a)
Protein Isoforms
Cholesterol
Therapeutics
1 Citation (Scopus)
180 Downloads (Pure)

Lipoprotein metabolism in an apoB-80 familial hypobetalipoproteinemia heterozygote

Hooper, A., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, K. G., Barrett, H., Van Bockxmeer, F. & Burnett, J., Jun 2016, In : Clinical Biochemistry. 49, 9, p. 720-722

Research output: Contribution to journalArticle

Open Access
File
Hypobetalipoproteinemias
Apolipoproteins B
Heterozygote
Metabolism
Lipoproteins
5 Citations (Scopus)
115 Downloads (Pure)

Lipoprotein Metabolism in APOB L343V Familial Hypobetalipoproteinemia.

Hooper, A., Heeks, L., Robertson, K., Champain, D., Hua, J., Song, S., Parhofer, P., Barrett, H., Van Bockxmeer, F. & Burnett, J., Nov 2015, In : Journal of Clinical Endocrinology and Metabolism. 100, 11, p. E1484-E1490 7 p.

Research output: Contribution to journalArticle

Open Access
File
Hypobetalipoproteinemias
Apolipoproteins B
Metabolism
Lipoproteins
Triglycerides
18 Citations (Scopus)

Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics

Tomazela, D. M., Patterson, B. W., Hanson, E., Spence, K. L., Kanion, T. B., Salinger, D. H., Vicini, P., Barrett, H., Heins, H. B., Cole, F. S., Hamvas, A. & Maccoss, M. J., 2010, In : Analytical Chemistry. 82, 6, p. 2561-2567

Research output: Contribution to journalArticle

23 Citations (Scopus)

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

Hodson, L., Banerjee, R., Rial, B., Arlt, W., Adiels, M., Boren, J., Marionou, K., Fisher, C., Mostad, I. L., Stratton, I. M., Barrett, H., Chan, D., Watts, G., Harnden, K., Karpe, F. & Fielding, B. A., 2015, In : Journal of the American Heart Association. 4, 10, p. 1-45

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Metabolism and proteomics of large and small dense LDL in combined hyperlipidemia: effects of rosuvastatin

Thongtang, N., Diffenderfer, M. R., Ooi, E. M. M., Barrett, P. H. R., Turner, S. M., Le, N-A., Brown, W. V. & Schaefer, E. J., Jul 2017, In : Journal of Lipid Research. 58, 7, p. 1315-1324 10 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Metabolism
Proteomics
Apolipoprotein B-100
Lipoproteins
5 Citations (Scopus)
Gonadotropin-Releasing Hormone
Steroids
Estradiol
Castration
Testis
11 Citations (Scopus)

Omega-3 fatty acid ethyl ester supplementation decreases very-low-density lipoprotein triacylglycerol secretion in obese men

Wong, A. T. Y., Chan, D., Ooi, E., Ng, T. W., Watts, G. & Barrett, H., Jul 2013, In : Clinical Science. 125, 1, p. 45-51

Research output: Contribution to journalArticle

VLDL Lipoproteins
Omega-3 Fatty Acids
Esters
Triglycerides
Apolipoprotein B-100