Find Research outputs

Search results

• A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis

  Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.

  Research output: Contribution to conference › Conference presentation/ephemera

• Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease

  Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, Gearry, R. B., Selby, W., Bell, S. J., Brown, S. J. & Connell, W. R., 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.

  Research output: Contribution to journal › Article

  • Adalimumab
  • Drug Monitoring
  • Crohn Disease
  • Recurrence
  • Anti-Idiotypic Antibodies
  6 Citations (Scopus)

• Anti-TNF Therapy in Pregnant Women with Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes

  Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 others, Andrews, J. M., Subramaniam, K., Moore, G. T., Jensen, N. M., Connor, S. J., Wildt, S., Wilson, B., Ellard, K., Christensen, L. A. & Bell, S. J., Jan 2020, In : Inflammatory Bowel Diseases. 26, 1, p. 93-102 10 p.

  Research output: Contribution to journal › Article

  • Inflammatory Bowel Diseases
  • Therapeutic Uses
  • Pregnant Women
  • Tumor Necrosis Factor-alpha
  • Parturition
  5 Citations (Scopus)

• Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series

  Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series

  Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents

  Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935

  Research output: Contribution to journal › Article
  12 Citations (Scopus)

• Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents

  Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418

  Research output: Contribution to journal › Article
  56 Citations (Scopus)

• Cellular and Molecular Mediators of Intestinal Fibrosis

  Lawrance, I., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J., Pellino, G., Reif, S., Speca, S. & Latella, G., Dec 2017, In : Journal of Crohn's and Colitis. 11, 12, p. 1491–1503 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Fibrosis
  • Inflammatory Bowel Diseases
  • Inflammation
  • Anti-Inflammatory Agents
  53 Citations (Scopus)

• Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program

  Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465

  Research output: Contribution to journal › Review article

• Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

  International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.

  Research output: Contribution to journal › Article

  Open Access

  • Machine Learning
  • Crohn Disease
  • Genome
  • Logistic Models
  • ROC Curve
  16 Citations (Scopus)

• Crohn's disease and smoking: Is it ever too late to quit?

  Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671

  Research output: Contribution to journal › Article
  30 Citations (Scopus)

• Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

  National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.

  Research output: Contribution to journal › Article

  • Genome-Wide Association Study
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Ulcerative Colitis
  • Genes
  512 Citations (Scopus)

• Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis

  Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, Mcgovern, D. P. B., Radford-Smith, G. L., Schreiber, S., Schumm, P. L., Sharma, Y., Silverberg, M. S., Weersma, R. K., D'Amato, M., Vermeire, S., Franke, A., Lettre, G., Xavier, R. J., Daly, M. J., Rioux, J. D., Aumais, G., Bernard, E. J., Cohen, A. Y., Deslandres, C., Lahaie, R. G., Paré, P., Cho, J. H., Targan, S. R., Schumm, P. P., Rutgeerts, P. J., Vermeire, S. A. F. A., Steinhart, A. H., Ahmad, T., Anderson, C. A., Baldassano, R. N., Balschun, T., Barclay, M. L., Barrett, J. C., Bayless, T. M., Bis, J. C. M., Brand, S., Bumpstead, S., Büning, C., Cohen, A., Colombel -, J. F., Cottone, M., D'Incà, R., Denson, T., Dubinsky, M. C., Edwards, C. M., Florin, T. H. J., Franchimont, D. P., Gearry, R. B., Georges, M. A. J. A. J., Glas, J., Van Gossum, A., Griffiths, A. M., Guthery, S. L., Hákonarson, H. H., Haritunians, T., Hugot, J. P., De Jong, D. J., Jostins, L., Kugathasan, S., Kullak- Ublick, G. A., Latiano, A., Laukens, D., Lawrance, I., Lee, J., Lees, C. W., Lémann, M., Levine, A. D., Libioulle, C., Louis, É. J., Mansfield, J. C., Mathew, C. G. P., Mitrovič, M., Montgomery, G. W., Mowat, C. E., Newman, W. G., Palmieri, O., Panés, J., Parkes, M., Phillips, A. M., Ponsioen, C. Y. J., Potočnik, U., Prescott, N. J., Proctor, D. D., Regueiro, M. D., Roberts, R. L., Rotter, J. I., Sanderson, J. D., Sans, M., Satsangi, J., Seibold, F., Simms, L. A., Taylor, K. D., Verspaget, H. W., De Vos, M. P., Walters, T. D., Wang, K., Whiteman, D. C. & Wijmenga, C., 2013, In : PLoS Genetics. 9, 9, p. 11 pp.

  Research output: Contribution to journal › Article

  Open Access

  • colitis
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn disease
  • loci
  116 Citations (Scopus)

• Detection of liver injury in IBD using transient elastography

  Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677

  Research output: Contribution to journal › Article

  • Elasticity Imaging Techniques
  • Inflammatory Bowel Diseases
  • Liver
  • Wounds and Injuries
  • Inflammatory Bowel Disease 5
  9 Citations (Scopus)

• Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice

  Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12pp

  Research output: Contribution to journal › Article

  Open Access
  42 Citations (Scopus)

• Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response

  Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.

  Research output: Contribution to journal › Article

  • Crohn Disease
  • Tumor Necrosis Factor-alpha
  • Adrenal Cortex Hormones
  • Physicians
  • Steroids
  1 Citation (Scopus)

• Dysplasia and colorectal cancer surveillance in inflammatory bowel disease

  Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Colorectal Neoplasms
  • Mesalamine
  • Needs Assessment
  • Chemoprevention
  9 Citations (Scopus)

• Efficacy of rectal tacrolimus for induction therapy in patients with resistant ulcerative proctitis

  Lawrance, I. C., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 1 Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1248-1255 8 p.

  Research output: Contribution to journal › Article

  • Proctitis
  • Tacrolimus
  • Placebos
  • Therapeutics
  • Ulcerative Colitis
  26 Citations (Scopus)

• Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer

  Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer

  Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.

  Research output: Contribution to journal › Article

  • emu Oil
  • Colitis
  • Colorectal Neoplasms
  • Dextran Sulfate
  • Azoxymethane
  11 Citations (Scopus)

• Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis

  Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis

  Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.

  Research output: Contribution to journal › Article

  • emu Oil
  • Ulcerative Colitis
  • Peroxidase
  • Water
  • Dextran Sulfate
  3 Citations (Scopus)

• European evidence based consensus for endoscopy in inflammatory bowel disease

  ECCO & Lawrance, I., 15 Dec 2013, In : Journal of Crohn's and Colitis. 7, 12, p. 982-1018 37 p.

  Research output: Contribution to journal › Article

  Open Access
  442 Citations (Scopus)

• Fine-mapping inflammatory bowel disease loci to single-variant resolution

  Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, Haritunians, T., Knight, J., Lawrance, I. C., Lees, C. W., Louis, E., Mariman, R., Meuwissen, T., Mni, M., Momozawa, Y., Parkes, M., Spain, S. L., Théâtre, E., Trynka, G., Satsangi, J., van Sommeren, S., Vermeire, S., Xavier, R. J., Weersma, R. K., Duerr, R. H., Mathew, C. G., Rioux, J. D., McGovern, D. P. B., Cho, J. H., Georges, M., Daly, M. J., Barrett, J. C. & International Inflammatory Bowel Disease Genetics Consortium, 13 Jul 2017, In : Nature. 547, 7662, p. 173-178 6 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn Disease
  • Epigenomics
  186 Citations (Scopus)

  430 Downloads (Pure)

• Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease

  Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245

  Research output: Contribution to journal › Article

  • Genetic Predisposition to Disease
  • Ulcerative Colitis
  • Crohn Disease
  • Single Nucleotide Polymorphism
  • Population Control
  27 Citations (Scopus)

• High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

  Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.

  Research output: Contribution to journal › Article

  Open Access

  • Colitis
  • Microbiota
  • Vitamin D
  • Dextran Sulfate
  • Serum Albumin
  20 Citations (Scopus)

• HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

  Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, Fedorak, R. N., Florin, T. H., Gaya, D. R., Greig, E., Halfvarson, J., Hart, A., Irving, P., Jones, G., Karban, A., Lawrance, I., Lee, J. C., Lees, C., Lev-Tzion, R., Lindsay, J. O., Mansfield, J., Mawdsley, J., Mazhar, Z., Parkes, M., Parnell, K., Orchard, T. R., Radford-Smith, G., Russell, R. K., Reffitt, D., Satsangi, J., Silverberg, M. S., Sturniolo, G. C., Tremelling, M., Tsianos, V., Van Heel, D. A., Walsh, A., Watermeyer, G., Weersma, R. K., Zeissig, S., Rossjohn, J., Holden, A. L., International Serious Adverse Events Consortium, I. S. A. E. C., Ibd Pharmacogenetics Study Group, IBD. P. S. G. & Ahmad, T., 2014, In : Nature Genetics. 46, 10, p. 1131-1136

  Research output: Contribution to journal › Article
  109 Citations (Scopus)

• Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, Achkar, J-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Büning, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Glas, J., Haritunians, T., Hart, A., Hawkey, C., Hedl, M., Hu, X., Karlsen, T. H., Kupcinskas, L., Kugathasan, S., Latiano, A., Laukens, D., Lawrance, I., Lees, C. W., Louis, E., Mahy, G., Mansfield, J., Morgan, A. R., Mowat, C., Newman, W., Palmieri, O., Ponsioen, C. Y., Potocnik, U., Prescott, N. J., Regueiro, M., Rotter, J. I., Russell, R. K., Sanderson, J. D., Sans, M., Satsangi, J., Schreiber, S., Simms, L. A., Sventoraityte, J., Targan, S. R., Taylor, K. D., Tremelling, M., Verspaget, H. W., De Vos, M., Wijmenga, C., Wilson, D. C., Winkelmann, J., Xavier, R. J., Zeissig, S., Zhang, B., Zhang, C. K., Zhao, H., Silverberg, M. S., Annese, V., Hakonarson, H., Brant, S. R., Radford-Smith, G., Mathew, C. G., Rioux, J. D., Schadt, E. E., Daly, M. J., Franke, A., Parkes, M., Vermeire, S., Barrett, J. C. & Cho, J. H., 1 Nov 2012, In : Nature. 491, 7422, p. 119-124

  Research output: Contribution to journal › Article

  • Host Microbial Interactions
  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn Disease
  2692 Citations (Scopus)

• IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

  The International IBD Genetics Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 2427.

  Research output: Contribution to journal › Article

  Open Access

  • genes
  • loci
  • Inflammatory Bowel Diseases
  • Genes
  • modules
  39 Citations (Scopus)

• Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease

  Walsh, A. J., Weltman, M., Burger, D., Vivekanandarajah, S., Connor, S., Howlett, M., Radford-Smith, G., Selby, W., Veillard, A. S., Grimm, M. C., Travis, S. P. L. & Lawrance, I., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, p. e449-e456

  Research output: Contribution to journal › Article
  32 Citations (Scopus)

• Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome

  Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.

  Research output: Contribution to journal › Review article

  • Ultraviolet Rays
  • Microbiota
  • Inflammatory Bowel Diseases
  • Vitamin D
  • Gastrointestinal Microbiome
  1 Citation (Scopus)

• Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study

  the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.

  Research output: Contribution to journal › Article

  • Adalimumab
  • Infliximab
  • New Zealand
  • Crohn Disease
  • Observational Studies
  23 Citations (Scopus)

• Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study

  Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293

  Research output: Contribution to journal › Article
  13 Citations (Scopus)

• Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease

  International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I. C., 6 Jun 2013, In : American Journal of Human Genetics. 92, 6, p. 1008-1012 5 p.

  Research output: Contribution to journal › Article

  Open Access

  • Machine Learning
  • Ulcerative Colitis
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Sample Size
  89 Citations (Scopus)

• Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients

  Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.

  Research output: Contribution to journal › Article

  • Keratinocytes
  • Inflammatory Bowel Diseases
  • Carcinoma
  • Solar System
  • Skin

• Mechanisms of initiation and progression of intestinal fibrosis in IBD

  Latella, G., Di Gregorio, J., Flati, V., Rieder, F. & Lawrance, I., 2014, In : Scandinavian Journal of Gastroenterology. 50, p. 53-65

  Research output: Contribution to journal › Review article
  80 Citations (Scopus)

• Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention

  Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708

  Research output: Contribution to journal › Article

  Open Access
  9 Citations (Scopus)

• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, Colombel, J-F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J-P., Jobin, G., Laukens, D., Lawrance, I., Lémann, M., Levine, A., Libioulle, C., Louis, E., Mcgovern, D. P., Milla, M., Montgomery, G. W., Morley, K. I., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panés, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L., Seielstad, M., Hillary Steinhart, A., Targan, S. R., Van Den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H-J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S. R., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., 2011, In : Nature Genetics. 43, 3, p. 246-252

  Research output: Contribution to journal › Article
  935 Citations (Scopus)

• Microbiota and management of inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140

  Research output: Contribution to journal › Review article
  3 Citations (Scopus)

• Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984

  Research output: Contribution to journal › Review article
  5 Citations (Scopus)

• NAFLD, the changing face of IBD

  Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease

  Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-Smith, G., Andrews, J. M. & 2 others, McHugh, P. C. & Barclay, M. L., 29 Nov 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.

  Research output: Contribution to journal › Article

  • 6-methylthiopurine
  • Guanine
  • Ligases
  • 6-thioguanylic acid
  • Inflammatory Bowel Diseases

• OP007 A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis

  Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 26 Jan 2017, In : JOURNAL OF CROHNS & COLITIS. 11, 1

  Research output: Contribution to journal › Abstract/Meeting Abstract

  Open Access

• Orally administered emu oil attenuates disease in a mouse model of Crohn’s-like colitis

  Mitchell, C. J., Howarth, G. S., Chartier, L. C., Trinder, D., Lawrance, I. C., Huang, L. S. & Mashtoub, S., Dec 2020, In : Experimental Biology and Medicine. 245, 18, p. 1697-1707

  Research output: Contribution to journal › Article

  • emu Oil
  • Colitis
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Colonoscopy
  1 Citation (Scopus)

• Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era

  Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498

  Research output: Contribution to journal › Article

  • Tacrolimus
  • Inflammatory Bowel Diseases
  • Crohn Disease
  • Necrosis
  • Therapeutics
  21 Citations (Scopus)

• PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease

  Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

  Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.

  Research output: Contribution to journal › Article

  Open Access

  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Crohn Disease
  • Ulcerative Colitis
  10 Citations (Scopus)

• Predictors of fibrostenotic Crohn's Disease

  Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007

  Research output: Contribution to journal › Article
  49 Citations (Scopus)

• Preventing infective complications in inflammatory bowel disease

  Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698

  Research output: Contribution to journal › Review article

  Open Access

  • Inflammatory Bowel Diseases
  • Opportunistic Infections
  • Physicians
  • Biological Factors
  • Patient Education
  9 Citations (Scopus)

• Prevention of cancer in IBD - A balancing act

  Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Inflammation
  • Immunosuppression
  • Lymphoma
  • Colorectal Neoplasms
  7 Citations (Scopus)