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  • Keith Stubbs

Transition-Metal-Free Cross-Coupling Reactions in Dynamic Thin Films To Access Pyrimidine and Quinoxaline Analogues

Ho, L. A., Raston, C. L. & Stubbs, K. A., Dec 2016, In : European Journal of Organic Chemistry. 2016, 36, p. 5957-5963

Research output: Contribution to journalArticle

7 Citations (Scopus)

Targeting plant DIHYDROFOLATE REDUCTASE with antifolates and mechanisms for genetic resistance

Corral, M. G., Haywood, J., Stehl, L. H., Stubbs, K. A., Murcha, M. W. & Mylne, J. S., 1 Aug 2018, In : Plant Journal. 95, 4, p. 727-742 16 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
205 Downloads (Pure)

Synthetic and Crystallographic Insight into Exploiting sp2 Hybridization in the Development of α-l-Fucosidase Inhibitors

Coyle, T., Wu, L., Debowski, A. W., Davies, G. J. & Stubbs, K. A., 3 Jun 2019, In : ChemBioChem. 20, 11, p. 1365-1368 4 p.

Research output: Contribution to journalArticle

Open Access

Syntheses and biological investigations of kirkamide and oseltamivir hybrid derivatives

Sieber, S., Hsiao, C. C., Emmanouilidou, D., Debowski, A. W., Stubbs, K. A. & Gademann, K., 14 Jul 2020, In : Tetrahedron. 131386.

Research output: Contribution to journalArticle

Open Access

Structure of a Talaromyces pinophilus GH62 arabinofuranosidase in complex with AraDNJ at 1.25A° resolution

Moroz, O. V., Sobala, L. F., Blagova, E., Coyle, T., Peng, W., Krogh, K. B. R. M., Stubbs, K. A., Wilson, K. S. & Davies, G. J., 1 Aug 2018, In : Acta Crystallographica Section F: Structural Biology Communications. 74, 8, p. 490-495 6 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut

Hemsworth, G. R., Thompson, A. J., Stepper, J., Sobala, T. F., Coyle, T., Larsbrink, J., Spadiut, O., Goddard-Borger, E. D., Stubbs, K., Brumer, H. & Davies, G. J., 27 Jul 2016, In : Open Biology. 6, 7, p. 1-14

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Potent inhibition of a GH20 exo-β-N-acetylglucosaminidase from marine Vibrio bacteria by reaction intermediate analogues

Meekrathok, P., Stubbs, K. A. & Suginta, W., 1 Aug 2018, In : International Journal of Biological Macromolecules. 115, p. 1165-1173 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
152 Downloads (Pure)

Modifying the phenyl group of PUGNAc: Reactivity tuning to deliver selective inhibitors for N-acetyl-d-glucosaminidases

Hattie, M., Cekic, N., Debowski, A., Vocadlo, D. J. & Stubbs, K., 23 Feb 2016, In : Organic and Biomolecular Chemistry. 14, 12, p. 3193-3197

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
289 Downloads (Pure)

Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori

Li, H., Liao, T., Debowski, A., Tang, H., Nilsson, H. O., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Dec 2016, In : Helicobacter. 21, 6, p. 445-461 17 p.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
497 Downloads (Pure)

Lipopolysaccharide structural differences between western and Asian Helicobacter pylori strains

Li, H., Tang, H., Debowski, A. W., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 8 Sep 2018, In : Toxins. 10, 9, 364.

Research output: Contribution to journalReview article

Open Access
5 Citations (Scopus)

Integrating thin film microfluidics in developing a concise synthesis of DGJNAc: A potent inhibitor of α-N-acetylgalctosaminidases

Wills, S. S., Raston, C. L. & Stubbs, K. A., 15 Dec 2018, In : Bioorganic and Medicinal Chemistry Letters. 28, 23-24, p. 3748-3751 4 p.

Research output: Contribution to journalArticle

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system

Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum

Li, H., Wei, H., Hu, J., Lacey, E., Sobolev, A. N., Stubbs, K. A., Solomon, P. S. & Chooi, Y. H., 17 Jan 2020, In : ACS Chemical Biology. 15, 1, p. 226-233

Research output: Contribution to journalArticle

General Synthesis of 3,4-Dinitrophenyl α-Glycopyranosides

Wallace, M. D. & Stubbs, K. A., 24 Oct 2019, In : ChemistrySelect. 4, 39, p. 11427-11429 3 p.

Research output: Contribution to journalArticle

Open Access
File
329 Downloads (Pure)

Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Hattie, M. & Stubbs, K. A., 16 Jan 2020, In : ChemistrySelect. 5, 2, p. 875-877 3 p.

Research output: Contribution to journalArticle

Enzyme targets for drug design of new anti-virulence therapeutics

Kahler, C. M., Sarkar-Tyson, M., Kibble, E. A., Stubbs, K. A. & Vrielink, A., 1 Dec 2018, In : Current Opinion in Structural Biology. 53, p. 140-150 11 p.

Research output: Contribution to journalReview article

Open Access
File
4 Citations (Scopus)
470 Downloads (Pure)

East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide

Li, H., Marceau, M., Yang, T., Liao, T., Tang, X., Hu, R., Xie, Y., Tang, H., Tay, A., Shi, Y., Shen, Y., Yang, T., Pi, X., Lamichhane, B., Luo, Y., Debowski, A. W., Nilsson, H. O., Haslam, S. M., Mulloy, B., Dell, A. & 3 others, Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Jan 2019, In : PLoS Genetics. 15, 11, e1008497.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Developing ciprofloxacin analogues against plant DNA gyrase: a novel herbicide mode of action

Wallace, M. D., Waraich, N. F., Debowski, A. W., Corral, M. G., Maxwell, A., Mylne, J. S. & Stubbs, K. A., 21 Feb 2018, In : Chemical Communications. 54, 15, p. 1869-1872 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Chemical Ecogenomics-Guided Discovery of Phytotoxic α-Pyrones from the Fungal Wheat Pathogen Parastagonospora nodorum

Li, H., Hu, J., Wei, H., Solomon, P. S., Vuong, D., Lacey, E., Stubbs, K. A., Piggott, A. M. & Chooi, Y. H., 5 Oct 2018, In : Organic Letters. 20, 19, p. 6148-6152 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Biosynthesis of a Tricyclo[6.2.2.02,7]dodecane System by a Berberine Bridge Enzyme-Like Aldolase

Li, H., Hu, J., Wei, H., Solomon, P. S., Stubbs, K. A. & Chooi, Y. H., 25 Sep 2019, In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Angled Vortex Fluidic Mediated Multicomponent Photocatalytic and Transition Metal-Catalyzed Reactions

Ho, L. A., Raston, C. L. & Stubbs, K. A., 21 Jun 2018, In : Chemistry - A European Journal. 24, 35, p. 8869-8874 6 p.

Research output: Contribution to journalArticle

File
5 Citations (Scopus)
210 Downloads (Pure)

Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human: O-GlcNAcase

Cekic, N., Heinonen, J. E., Stubbs, K., Roth, C., He, Y., Bennet, A. J., Mceachern, E. J., Davies, G. J. & Vocadlo, D. J., 2016, In : Chemical Science. 7, 6, p. 3742-3750

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

A mechanism-based GlcNAc-inspired cyclophellitol inactivator of the peptidoglycan recycling enzyme NagZ reverses resistance to β-lactams in Pseudomonas aeruginosa

Ho, L. A., Winogrodzki, J. L., Debowski, A. W., Madden, Z., Vocadlo, D. J., Mark, B. L. & Stubbs, K. A., 1 Jan 2018, In : Chemical Communications. 54, 75, p. 10630-10633 4 p.

Research output: Contribution to journalArticle

File
3 Citations (Scopus)
322 Downloads (Pure)

A herbicide structure–activity analysis of the antimalarial lead compound MMV007978 against Arabidopsis thaliana

Corral, M. G., Leroux, J., Tresch, S., Newton, T., Stubbs, K. A. & Mylne, J. S., 1 Jul 2018, In : Pest Management Science. 74, 7, p. 1558-1563 6 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

A Fluorescent Transport Assay Enables Studying AmpG Permeases Involved in Peptidoglycan Recycling and Antibiotic Resistance

Perley-Robertson, G. E., Yadav, A. K., Winogrodzki, J. L., Stubbs, K., Mark, B. L. & Vocadlo, D. J., 2016, In : ACS Chemical Biology. 11, 9, p. 2626-2635

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)