Find Research Outputs

Search in all content

Filters for Research Output

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2017
  • 2016

Author

  • Keith Stubbs

Vortex Fluidic Chemical Transformations

Britton, J., Stubbs, K. A., Weiss, G. A. & Raston, C. L., 27 Sep 2017, In : Chemistry: A European Journal. 23, 54, p. 13270–13278 9 p.

Research output: Contribution to journalReview article

39 Citations (Scopus)

Understanding protein glycosylation pathways in bacteria

Li, H., Debowski, A. W., Liao, T., Tang, H., Nilsson, H-O., Marshall, B. J., Stubbs, K. A. & Benghezal, M., 1 Jan 2017, In : Future Microbiology. 12, 1, p. 59-72 14 p.

Research output: Contribution to journalReview article

Open Access
File
9 Citations (Scopus)
623 Downloads (Pure)

Transition-Metal-Free Cross-Coupling Reactions in Dynamic Thin Films To Access Pyrimidine and Quinoxaline Analogues

Ho, L. A., Raston, C. L. & Stubbs, K. A., Dec 2016, In : European Journal of Organic Chemistry. 2016, 36, p. 5957-5963

Research output: Contribution to journalArticle

7 Citations (Scopus)

The redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains

Li, H., Yang, T., Liao, T., Debowski, A. W., Nilsson, H., Fulurija, A., Haslam, S., Mulloy, B., Dell, A., Stubbs, K. A., Marshall, B. J. & Benghezal, M., Sep 2017, In : Helicobacter. 22, 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

The redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains

Li, H., Yang, T., Liao, T., Debowski, A. W., Nilsson, H. O., Fulurija, A., Haslam, S. M., Mulloy, B., Dell, A., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 17 Mar 2017, In : PLoS Pathogens. 13, 3, e1006280.

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)

The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors

Sato, M., Liebschner, D., Yamada, Y., Matsugaki, N., Arakawa, T., Wills, S. S., Hattie, M., Stubbs, K. A., Ito, T., Senda, T., Ashida, H. & Fushinobu, S., 21 Jul 2017, In : Journal of Biological Chemistry. 292, 29, p. 12126-12138 13 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Synthetic and Crystallographic Insight into Exploiting sp2 Hybridization in the Development of α-l-Fucosidase Inhibitors

Coyle, T., Wu, L., Debowski, A. W., Davies, G. J. & Stubbs, K. A., 3 Jun 2019, In : ChemBioChem. 20, 11, p. 1365-1368 4 p.

Research output: Contribution to journalArticle

Open Access

Syntheses and biological investigations of kirkamide and oseltamivir hybrid derivatives

Sieber, S., Hsiao, C. C., Emmanouilidou, D., Debowski, A. W., Stubbs, K. A. & Gademann, K., 14 Jul 2020, In : Tetrahedron. 131386.

Research output: Contribution to journalArticle

Open Access

Synergistic activity of fosfomycin, β-lactams and peptidoglycan recycling inhibition against Pseudomonas aeruginosa

Hamou-Segarra, M., Zamorano, L., Vadlamani, G., Chu, M., Sanchez-Diener, I., Juan, C., Blazquez, J., Hattie, M., Stubbs, K. A., Mark, B. L. & Oliver, A., 1 Feb 2017, In : Journal of Antimicrobial Chemotherapy. 72, 2, p. 448-454 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

Anandan, A., Evans, G. L., Condic-Jurkic, K., O'Mara, M. L., John, C. M., Phillips, N. J., Jarvis, G. A., Wills, S. S., Stubbs, K. A., Moraes, I., Kahler, C. M. & Vrielink, A., 28 Feb 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 9, p. 2218-2223 6 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)

Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut

Hemsworth, G. R., Thompson, A. J., Stepper, J., Sobala, T. F., Coyle, T., Larsbrink, J., Spadiut, O., Goddard-Borger, E. D., Stubbs, K., Brumer, H. & Davies, G. J., 27 Jul 2016, In : Open Biology. 6, 7, p. 1-14

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Molecular Insight into Evolution of Symbiosis between Breast-Fed Infants and a Member of the Human Gut Microbiome Bifidobacterium longum

Yamada, C., Gotoh, A., Sakanaka, M., Hattie, M., Stubbs, K. A., Katayama-Ikegami, A., Hirose, J., Kurihara, S., Arakawa, T., Kitaoka, M., Okuda, S., Katayama, T. & Fushinobu, S., 6 Apr 2017, In : Cell Chemical Biology. 24, 4, p. 515–524 e5.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Modifying the phenyl group of PUGNAc: Reactivity tuning to deliver selective inhibitors for N-acetyl-d-glucosaminidases

Hattie, M., Cekic, N., Debowski, A., Vocadlo, D. J. & Stubbs, K., 23 Feb 2016, In : Organic and Biomolecular Chemistry. 14, 12, p. 3193-3197

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
289 Downloads (Pure)

Lipopolysaccharide Structure and Biosynthesis in Helicobacter pylori

Li, H., Liao, T., Debowski, A., Tang, H., Nilsson, H. O., Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Dec 2016, In : Helicobacter. 21, 6, p. 445-461 17 p.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
497 Downloads (Pure)

Insights from the redefinition of Helicobacter pylori lipopolysaccharide O-antigen and core-oligosaccharide domains

Li, H., Yang, T., Liao, T., Debowski, A. W., Nilsson, H-O., Haslam, S. M., Dell, A., Stubbs, K. A., Marshall, B. J. & Benghezal, M., May 2017, In : Microbial Cell. 4, 5, p. 175-178 4 p.

Research output: Contribution to journalEditorial

Open Access
3 Citations (Scopus)

Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast

Yap, H. Y. Y., Muria-Gonzalez, M. J., Kong, B. H., Stubbs, K. A., Tan, C. S., Ng, S. T., Tan, N. H., Solomon, P. S., Fung, S. Y. & Chooi, Y. H., 12 Jun 2017, In : Microbial Cell Factories. 16, 1, 103.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Heterologous biosynthesis of elsinochrome A sheds light on the formation of the photosensitive perylenequinone system

Hu, J., Sarrami, F., Li, H., Zhang, G., Stubbs, K. A., Lacey, E., Stewart, S. G., Karton, A., Piggott, A. M. & Chooi, Y-H., 7 Feb 2019, In : Chemical Science. 10, 5, p. 1457-1465 9 p.

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Herbicidal properties of antimalarial drugs

Corral, M. G., Leroux, J., Stubbs, K. A. & Mylne, J. S., 31 Mar 2017, In : Scientific Reports. 7, 45871.

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection

Debowski, A. W., Walton, S. M., Chua, E-G., Tay, A. C-Y., Liao, T., Lamichhane, B., Himbeck, R., Stubbs, K. A., Marshall, B. J., Fulurija, A. & Benghezal, M., Jun 2017, In : PLoS Pathogens. 13, 6, 21 p., 1006464.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Genomics-Driven Discovery of Phytotoxic Cytochalasans Involved in the Virulence of the Wheat Pathogen Parastagonospora nodorum

Li, H., Wei, H., Hu, J., Lacey, E., Sobolev, A. N., Stubbs, K. A., Solomon, P. S. & Chooi, Y. H., 17 Jan 2020, In : ACS Chemical Biology. 15, 1, p. 226-233

Research output: Contribution to journalArticle

General Synthesis of 3,4-Dinitrophenyl α-Glycopyranosides

Wallace, M. D. & Stubbs, K. A., 24 Oct 2019, In : ChemistrySelect. 4, 39, p. 11427-11429 3 p.

Research output: Contribution to journalArticle

Open Access
File
329 Downloads (Pure)

Generalising a Simple Methodology for the Regioselective Anomeric Deacetylation of Carbohydrates

Hattie, M. & Stubbs, K. A., 16 Jan 2020, In : ChemistrySelect. 5, 2, p. 875-877 3 p.

Research output: Contribution to journalArticle

Exploiting the Evolutionary Relationship between Malarial Parasites and Plants To Develop New Herbicides

Corral, M. G., Leroux, J., Tresch, S., Newton, T., Stubbs, K. A. & Mylne, J. S., 7 Aug 2017, In : Angewandte Chemie - International Edition. 56, 33, p. 9881-9885 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Exploiting sp2-Hybridisation in the Development of Potent 1,5-α-l-Arabinanase Inhibitors

Coyle, T., Debowski, A. W., Varrot, A. & Stubbs, K. A., 1 Jun 2017, In : ChemBioChem. 18, 11, p. 974-978 5 p.

Research output: Contribution to journalArticle

East-Asian Helicobacter pylori strains synthesize heptan-deficient lipopolysaccharide

Li, H., Marceau, M., Yang, T., Liao, T., Tang, X., Hu, R., Xie, Y., Tang, H., Tay, A., Shi, Y., Shen, Y., Yang, T., Pi, X., Lamichhane, B., Luo, Y., Debowski, A. W., Nilsson, H. O., Haslam, S. M., Mulloy, B., Dell, A. & 3 others, Stubbs, K. A., Marshall, B. J. & Benghezal, M., 1 Jan 2019, In : PLoS Genetics. 15, 11, e1008497.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance

Vadlamani, G., Stubbs, K. A., Désiré, J., Blériot, Y., Vocadlo, D. J. & Mark, B. L., 1 Jun 2017, In : Protein Science. 26, 6, p. 1161-1170 10 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Carrageenan catabolism is encoded by a complex regulon in marine heterotrophic bacteria

Ficko-Blean, E., Préchoux, A., Thomas, F., Rochat, T., Larocque, R., Zhu, Y., Stam, M., Génicot, S., Jam, M., Calteau, A., Viart, B., Ropartz, D., Pérez-Pascual, D., Correc, G., Matard-Mann, M., Stubbs, K. A., Rogniaux, H., Jeudy, A., Barbeyron, T., Médigue, C. & 5 others, Czjzek, M., Vallenet, D., McBride, M. J., Duchaud, E. & Michel, G., 1 Dec 2017, In : Nature Communications. 8, 1, 1685.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

Biosynthesis of a Tricyclo[6.2.2.02,7]dodecane System by a Berberine Bridge Enzyme-Like Aldolase

Li, H., Hu, J., Wei, H., Solomon, P. S., Stubbs, K. A. & Chooi, Y. H., 25 Sep 2019, In : Chemistry - A European Journal.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human: O-GlcNAcase

Cekic, N., Heinonen, J. E., Stubbs, K., Roth, C., He, Y., Bennet, A. J., Mceachern, E. J., Davies, G. J. & Vocadlo, D. J., 2016, In : Chemical Science. 7, 6, p. 3742-3750

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

A Fluorescent Transport Assay Enables Studying AmpG Permeases Involved in Peptidoglycan Recycling and Antibiotic Resistance

Perley-Robertson, G. E., Yadav, A. K., Winogrodzki, J. L., Stubbs, K., Mark, B. L. & Vocadlo, D. J., 2016, In : ACS Chemical Biology. 11, 9, p. 2626-2635

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Acquisition of the capsule locus by horizontal gene transfer in Neisseria meningitidis is often accompanied by the loss of UDP-GalNAc synthesis

Bartley, S. N., Mowlaboccus, S., Mullally, C. A., Stubbs, K. A., Vrielink, A., Maiden, M. C. J., Harrison, O. B., Perkins, T. T. & Kahler, C. M., 14 Mar 2017, In : Scientific Reports. 7, 14 p., 44442.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)