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  • Markus Schlaich

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Booth, L. C., Schlaich, M. P., Nishi, E. E., Yao, S. T., Xu, J., Ramchandra, R., Lambert, G. W. & May, C. N., 1 Jul 2015, In : International Journal of Cardiology. 190, 1, p. 220-226 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
59 Downloads (Pure)

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Shaping the future of renal denervation-the relevance of sham-controlled randomized trials and recent meta-analyses

Galindo Kiuchi, M., Ho, J., Lugo Gavidia, L. M. & Schlaich, M., 2019, In : Journal of American College of Cardiology. 73, p. 1633-1642

Research output: Contribution to journalEditorial

21 Citations (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
1 Citation (Scopus)

Rosuvastatin improves pulse wave reflection by restoring endothelial function

Ott, C., Schneider, M. P., Schlaich, M. P. & Schmieder, R. E., Jul 2012, In : Microvascular Research. 84, 1, p. 60-64 5 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Role of the Sympathetic Nervous System in Stress-Mediated Cardiovascular Disease

Hering, D., Lachowska, K. & Schlaich, M., Oct 2015, In : Current Hypertension Reports. 17, 10, p. 1-9 9 p., 80.

Research output: Contribution to journalReview article

29 Citations (Scopus)

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2

Matthews, V. B., Elliot, R. H., Rudnicka, C., Hricova, J., Herat, L. & Schlaich, M. P., 1 Oct 2017, In : Journal of Hypertension. 35, 10, p. 2059–2068

Research output: Contribution to journalArticle

37 Citations (Scopus)

Role of the sympathetic nervous system and its modulation in renal hypertension

Sata, Y., Head, G. A., Denton, K., May, C. N. & Schlaich, M. P., 29 Mar 2018, In : Frontiers in Medicine. 5, March, 82.

Research output: Contribution to journalReview article

Open Access
20 Citations (Scopus)

Reverse cardiac remodeling after renal denervation: Atrial electrophysiologic and structural changes associated with blood pressure lowering

Mclellan, A. J. A., Schlaich, M., Taylor, A. J., Prabhu, S. G. S., Hering, D., Hammond, L., Marusic, P., Duval, J., Sata, Y., Ellims, A. H., Esler, M. D., Peter, K., Shaw, J. A., Walton, A. S., Kalman, J. M. & Kistler, P. M., 1 May 2015, In : Heart Rhythm. 12, 5, p. 982-990

Research output: Contribution to journalArticle

37 Citations (Scopus)
1 Citation (Scopus)

Response to quality of life after renal denervation

Lambert, G. W., Hering, D., Esler, M. D., Marusic, P., Lambert, E. A., Tanamas, S. K., Shaw, J., Krum, H., Dixon, J. B., Barton, D. A. & Schlaich, M. P., Apr 2013, In : Hypertension. 61, 4

Research output: Contribution to journalLetter

Open Access
2 Citations (Scopus)

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access

Response to letter regarding article, "effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study"

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 15 Nov 2011, In : Circulation. 124, 20

Research output: Contribution to journalLetter

Open Access

Response to letter regarding article, "ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension"

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 20 May 2014, In : Circulation. 129, 20

Research output: Contribution to journalLetter

Open Access

Resistant Hypertension: Which Agent?

Prosser, H. C. G., Azzam, O. & Schlaich, M. P., 1 Aug 2018, In : Heart Lung and Circulation. 27, 8, p. 911-916 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Reply to letter to the Editor entitled: Ambulatory arterial stiffness index: a (too) easy predictor for renal denervation success?

Sata, Y., Head, G. A., Esler, M. D. & Schlaich, M. P., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1606-1607 2 p.

Research output: Contribution to journalLetter

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Renal sympathetic nerve ablation for the management of resistant hypertension: An update

Thorp, A. A., Larsen, R. N. & Schlaich, M. P., Nov 2013, In : Current Opinion in Nephrology and Hypertension. 22, 6, p. 607-614 8 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Renal sympathetic nerve ablation: The new frontier in the treatment of hypertension

Schlaich, M. P., Krum, H. & Sobotka, P. A., 1 Feb 2010, In : Current Hypertension Reports. 12, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

34 Citations (Scopus)

Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial

Stoiber, L., Mahfoud, F., Zamani, S. M., Lapinskas, T., Böhm, M., Ewen, S., Kulenthiran, S., Schlaich, M. P., Esler, M. D., Hammer, T., Stensæth, K. H., Pieske, B., Dreysse, S., Fleck, E., Kühne, T., Kelm, M., Stawowy, P. & Kelle, S., 1 Aug 2018, In : Clinical Research in Cardiology. 107, 8, p. 642-652 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

Esler, M. D., Krum, H., Sobotka, P. A., Schlaich, M. P., Schmieder, R. E., Böhm, M., Mahfoud, F., Sievert, H., Wunderlich, N., Rump, L. C., Vonend, O., Uder, M., Lobo, M., Caulfield, M., Erglis, A., Azizi, M., Sapoval, M., Thambar, S., Persu, A., Renkin, J. & 24 others, Schunkert, H., Weil, J., Hoppe, U. C., Walton, T., Scheinert, D., Binder, T., Januszewicz, A., Witkowski, A., Ruilope, L. M., Whitbourn, R., Bruck, H., Downes, M., Lüscher, T. F., Jardine, A. G., Webster, M. W., Zeller, T., Sadowski, J., Bartus, K., Straley, C. A., Barman, N. C., Lee, D. P., Witteles, R. M., Bhalla, V. & Massaro, J. M., 4 Dec 2010, In : The Lancet. 376, 9756, p. 1903-1909 7 p.

Research output: Contribution to journalArticle

1674 Citations (Scopus)

Renal sympathetic denervation for treatment of drug-resistant hypertension: One-year results from the symplicity htn-2 randomized, controlled trial

Esler, M. D., Krum, H., Schlaich, M., Schmieder, R. E., Böhm, M. & Sobotka, P. A., 18 Dec 2012, In : Circulation. 126, 25, p. 2976-2982 7 p.

Research output: Contribution to journalArticle

Open Access
353 Citations (Scopus)

Renal Sympathetic Denervation

Schlaich, M., 2015, Chronic Kidney Disease and Hypertension. Weir, M. R. & Lerma, E. V. (eds.). New York: Humana Press, p. 69-81

Research output: Chapter in Book/Conference paperChapter

Renal sympathetic denervation: a viable option for treating resistant hypertension

Schlaich, M. P., Sep 2017, In : American Journal of Hypertension. 30, 9, p. 847-856 10 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Renal nerve ablation reduces blood pressure in a patient with renovascular hypertension resistant to drug and revascularisation therapies

Hering, D., Walton, A., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 23 Aug 2012, In : International Journal of Cardiology. 159, 2

Research output: Contribution to journalArticle

9 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Cremers, B., Janker, J., Link, B., Vonend, O., Ukena, C., Linz, D., Schmieder, R., Rump, L. C., Kindermann, I., Sobotka, P. A., Krum, H., Scheller, B., Schlaich, M., Laufs, U. & Böhm, M., 1 Aug 2012, In : Hypertension. 60, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

Open Access
240 Citations (Scopus)

Renal Denervation Update From the International Sympathetic Nervous System Summit

Kiuchi, M. G., Esler, M. D., Fink, G. D., Osborn, J. W., Banek, C. T., Boehm, M., Denton, K. M., DiBona, G. F., Everett, T. H., Grassi, G., Katholi, R. E., Knuepfer, M. M., Kopp, U. C., Lefer, D. J., Lohmeier, T. E., May, C. N., Mahfoud, F., Paton, J. F. R., Schmieder, R. E., Pellegrino, P. R. & 2 others, Sharabi, Y. & Schlaich, M. P., 18 Jun 2019, In : Journal of the American College of Cardiology. 73, 23, p. 3006-3017 12 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

Zaldivia, M. T. K., Rivera, J., Hering, D., Marusic, P., Sata, Y., Lim, B., Eikelis, N., Lee, R., Lambert, G. W., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Eisenhardt, S. U., Flierl, U., Schlaich, M. P. & Peter, K., 1 Feb 2017, In : Hypertension. 69, 2, p. 323-331 9 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
212 Downloads (Pure)

Renal Denervation - Ready for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M., Galindo Kiuchi, M. & Esler, M. D., Aug 2018, In : Hypertension. 72, p. 287–290

Research output: Contribution to journalEditorial

Renal DenervationReady for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M. P., Kiuchi, M. G. & Esler, M. D., Aug 2018, In : Hypertension. 72, 2, p. 287-290 4 p.

Research output: Contribution to journalEditorial

5 Citations (Scopus)

Renal denervation in moderate to severe CKD

Hering, D., Mahfoud, F., Walton, A. S., Krum, H., Lambert, G. W., Lambert, E. A., Sobotka, P. A., Böhm, M., Cremers, B., Esler, M. D. & Schlaich, M. P., 1 Jul 2012, In : Journal of the American Society of Nephrology. 23, 7, p. 1250-1257 8 p.

Research output: Contribution to journalArticle

Open Access
270 Citations (Scopus)

Renal denervation in less severe forms of (resistant) hypertension—Quo vadis?

Schlaich, M. P., Hering, D. & Sata, Y., 1 Apr 2017, In : Journal of Clinical Hypertension. 19, 4, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation in human hypertension: Mechanisms, current findings, and future prospects

Schlaich, M. P., Hering, D., Sobotka, P. A., Krum, H. & Esler, M. D., 1 Jun 2012, In : Current Hypertension Reports. 14, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Renal Denervation for Treating Hypertension Current Scientific and Clinical Evidence

Weber, M. A., Mahfoud, F., Schmieder, R. E., Kandzari, D. E., Tsioufis, K. P., Townsend, R. R., Kario, K., Bohm, M., Sharp, A. S. P., Davies, J. E., Osborn, J. W., Fink, G. D., Euler, D. E., Cohen, D. L., Schlaich, M. P. & Esler, M. D., 24 Jun 2019, In : JACC: Cardiovascular Interventions. 12, 12, p. 1095-1105 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Renal denervation for resistant hypertension—the Symplicity HTN-1 study – Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 1 May 2014, In : The Lancet. 383, 9932, p. 1885-1886

Research output: Contribution to journalLetter

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

Renal denervation and pulmonary vein isolation in patients with drug resistant hypertension and symptomatic atrial fibrillation

Wilson, S., Kistler, P. M., Mclellan, A. J. A., Hering, D. & Schlaich, M., 2014, In : JOURNAL OF ATRIAL FIBRILLATION. 7, 4, p. 69-74

Research output: Contribution to journalReview article

1 Citation (Scopus)

Renal denervation and hypertension

Schlaich, M. P., Krum, H., Sobotka, P. A. & Esler, M. D., Jun 2011, In : American Journal of Hypertension. 24, 6, p. 635-642 8 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)

Renal Denervation After the SPYRAL HTN-OFF MED Trial Putting a Complex Study Into Context

Schlaich, M. P. & Esler, M. D., Dec 2017, In : Hypertension. 70, 6, p. 1076-1079 4 p.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Renal denervation: A new approach to treatment of resistant hypertension

Heuser, R. R. (ed.), Schlaich, M. (ed.) & Sievert, H. (ed.), 2015, New York: Springer-Verlag London Ltd. 201 p.

Research output: Book/ReportBook