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Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis
Jones, A. P., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Geldenhuys, S., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H., May 2017, In : Clinical & Translational Immunology. 6, 5, e143.Research output: Contribution to journal › Article
Open Access -
Altered regulatory T-cell fractions and Helios expression in Clinically Isolated Syndrome
Jones, A., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Geldenhuys, S., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H., Nov 2017, In : Multiple Sclerosis. 23, 13, p. NP7-NP7 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study
Hart, P. H., Jones, A. P., Trend, S., Cha, L., Fabis-Pedrini, M. J., Cooper, M. N., d'Este, C., Geldenhuys, S., Carroll, W. M., Byrne, S. N., Booth, D. R., Cole, J. M., Lucas, R. M. & Kermode, A. G., 22 May 2018, In : Multiple Sclerosis Journal - Experimental, Translational and Clinical. 4, 2, 6 p.Research output: Contribution to journal › Article
Open Access -
Are low sun exposure and/or vitamin D risk factors for type 1 diabetes?
Miller, K. M., Hart, P. H., de Klerk, N. H., Davis, E. A. & Lucas, R. M., 1 Mar 2017, In : PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES. 16, 3, p. 381-398 18 p.Research output: Contribution to journal › Article
Open Access5 Citations (Scopus) -
Are there differences in immune responses following delivery of vaccines through acutely or chronically sun-exposed compared with sun-unexposed skin?
Hart, P. H. & Norval, M., 8 Oct 2019, In : Immunology.Research output: Contribution to journal › Review article
Open Access -
Can skin exposure to sunlight prevent liver inflammation?
Gorman, S., Black, L., Feelisch, M., Hart, P. & Weller, R., 5 May 2015, In : Nutrients. 7, 5, p. 3219-3239Research output: Contribution to journal › Review article
Open Access8 Citations (Scopus) -
Cellular and molecular mechanisms of vitamin D in food allergy
Poole, A., Song, Y., Brown, H., Hart, P. H. & Zhang, G. B., 1 Jul 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3270-3277 8 p.Research output: Contribution to journal › Review article
Open Access8 Citations (Scopus) -
Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue
Dhamrait, G. K., Panchal, K., Fleury, N. J., Abel, T. N., Ancliffe, M. K., Crew, R. C., Croft, K., Fernandez, B. O., Minnion, M., Hart, P. H., Lucas, R. M., Mark, P. J., Feelisch, M., Weller, R. B., Matthews, V. & Gorman, S., 29 Aug 2019, In : Diabetologia.Research output: Contribution to journal › Article
5 Citations (Scopus) -
Circulating immune cells in multiple sclerosis
Jones, A. P., Kermode, A. G., Lucas, R. M., Carroll, W. M., Nolan, D. & Hart, P. H., 1 Feb 2017, In : Clinical and Experimental Immunology. 187, 2, p. 193-203 11 p.Research output: Contribution to journal › Review article
Open AccessFile27 Citations (Scopus)270 Downloads (Pure) -
Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function: The Sun Exposure and Vitamin D Supplementation (SEDS) Study
Hartley, M., Hoare, S., Lithander, F. E., Neale, R. E., Hart, P., Gorman, S., Gies, P. H. F., Sherriff, J. L., Swaminathan, A., Beilin, L., Mori, T., King, L., Black, L., Marshall, K., Xiang, F., Wyatt, C., King, K., Slevin, T. J., Pandeya, N. & Lucas, R., 2015, In : BMC Public Health. 15, 1, p. 1-9Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
Corrigendum to "The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva" [J. Steroid Biochem. Mol. Biol. 194 (2019) 105437]
Clarke, M. W., Black, L. J., Hart, P. H., Jones, A. P., Palmer, D. J., Siafarikas, A., Lucas, R. M. & Gorman, S., 9 Nov 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 105474.Research output: Contribution to journal › Comment/debate
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Cross-presentation of cutaneous melanoma antigen by migratory XCR1+CD103− and XCR1+CD103+ dendritic cells
Wylie, B., Seppanen, E., Xiao, K., Zemek, R., Zanker, D., Prato, S., Foley, B., Hart, P., Kroczek, R. A., Chen, W. & Waithman, J., 2015, In : OncoImmunology. 4, 8, p. 1-11Research output: Contribution to journal › Article
19 Citations (Scopus) -
Differences in control by UV radiation of inflammatory airways disease in naïve and allergen pre-sensitised mice
Scott, N. M., Lambert, M. J. M., Gorman, S., Mcglade, J. P. & Hart, P., 2011, In : Photochemical and Photobiological Sciences. 10, 12, p. 1894-1901Research output: Contribution to journal › Article
5 Citations (Scopus) -
Effects of UVR exposure on the gut microbiota of mice and humans
Ghaly, S., Kaakoush, N. O. & Hart, P. H., 1 Jan 2020, In : Photochemical and Photobiological Sciences. 19, 1, p. 20-28 9 p.Research output: Contribution to journal › Review article
1 Citation (Scopus) -
Evolving identification of blood cells associated with clinically isolated syndrome: Importance of time since clinical presentation and diagnostic MRI
Trend, S., Jones, A. P., Geldenhuys, S., Byrne, S. N., Fabis-Pedrini, M. J., Nolan, D., Booth, D. R., Carroll, W. M., Lucas, R. M., Kermode, A. G. & Hart, P. H., 15 Jun 2017, In : International Journal of Molecular Sciences. 18, 6, 1277.Research output: Contribution to journal › Article
Open Access6 Citations (Scopus) -
Exposure to solar UVR suppresses cell-mediated immunization responses in humans: The Australian Ultraviolet Radiation and Immunity Study
Swaminathan, A., Harrison, S. L., Ketheesan, N., van den Boogaard, C. H. A., Dear, K., Allen, M., Hart, P. H., Cook, M. & Lucas, R. M., Jul 2019, In : Journal of Investigative Dermatology. 139, 7, p. 1545–1553Research output: Contribution to journal › Article
Open Access5 Citations (Scopus) -
Exposure to Ultraviolet Radiation in the Modulation of Human Diseases
Hart, P. H., Norval, M., Byrne, S. N. & Rhodes, L. E., 1 Jan 2019, In : Annual Review of Pathology: Mechanisms of Disease. 14, p. 55-81 27 p.Research output: Contribution to journal › Review article
27 Citations (Scopus) -
Expression of MS risk genes in whole blood of CIS patients treated with narrow band UVB phototherapy
Gatt, P., Lucas, R. M., Carroll, W. M., Nolan, D., Cole, J. M., Jones, A. P., Trend, S., Cha, L., Kermode, A. G., Hart, P. H. & Booth, D. R., Nov 2017, In : Multiple Sclerosis. 23, 13, p. NP14-NP14 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis
Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.Research output: Contribution to journal › Article
Open Access18 Citations (Scopus) -
Higher serum immunoglobulin G3 levels may predict the development of multiple sclerosis in individuals with clinically isolated syndrome
Trend, S., Jones, A. P., Cha, L., Byrne, S. N., Geldenhuys, S., Fabis-Pedrini, M. J., Carroll, W. M., Cole, J. M., Booth, D. R., Lucas, R. M., Kermode, A. G., French, M. A. & Hart, P. H., 13 Jul 2018, In : Frontiers in Immunology. 9, JUL, 1590.Research output: Contribution to journal › Article
Open Access10 Citations (Scopus) -
IgG3 + B cells are associated with the development of multiple sclerosis
Marsh-Wakefield, F., Ashhurst, T., Trend, S., McGuire, H. M., Juillard, P., Zinger, A., Jones, A. P., Kermode, A. G., Hawke, S., Grau, G. E., Hart, P. H. & Byrne, S. N., 1 May 2020, In : Clinical and Translational Immunology. 9, 5, e1133.Research output: Contribution to journal › Article
Open Access3 Citations (Scopus) -
Immune mechanisms by which topically applied vitamin D acts as a therapeutic agent
Gorman, S. & Hart, P. H., 1 Dec 2011, Vitamin D: Biochemistry, Nutrition and Roles. Nova Science Publishers, p. 167-181 15 p.Research output: Chapter in Book/Conference paper › Chapter
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Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome
Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.Research output: Contribution to journal › Review article
1 Citation (Scopus) -
Insufficient sun exposure has become a real public health problem
Alfredsson, L., Armstrong, B. K., Allan Butterfield, D., Chowdhury, R., de Gruijl, F. R., Feelisch, M., Garland, C. F., Hart, P. H., Hoel, D. G., Jacobsen, R., Lindqvist, P. G., Llewellyn, D. J., Tiemeier, H., Weller, R. B. & Young, A. R., 13 Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 14, p. 1-15 15 p., 5014.Research output: Contribution to journal › Review article
Open Access3 Citations (Scopus) -
Introduction to the themed issue The health benefits of UV radiation exposure through Vitamin D production or non-Vitamin D pathways
Hart, P. H., Norval, M. & Reeve, V. E., 2017, In : Photochemical and Photobiological Sciences. 16, 3, p. 281-282 2 p.Research output: Contribution to journal › Editorial
2 Citations (Scopus) -
Investigating the roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammation by vitamin D
Gorman, S., Geldenhuys, S., Weeden, C., Grimbaldeston, M. A. & Hart, P., 1 Apr 2018, In : Archives of Dermatological Research. 310, 3, p. 221-230 10 p.Research output: Contribution to journal › Article
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Low-dose UV radiation before running wheel access activates brown adipose tissue
Allemann, T. S., Dhamrait, G. K., Fleury, N. J., Abel, T. N., Hart, P. H., Lucas, R. M., Matthews, V. B. & Gorman, S., 1 Mar 2020, In : The Journal of Endocrinology. 244, 3, p. 473-486 14 p.Research output: Contribution to journal › Article
Open Access1 Citation (Scopus) -
Modulation of the immune system by UV radiation: More than just the effects of vitamin D?
Hart, P., Gorman, S. & Finlay-Jones, J. J., 2011, In : Nature Reviews Immunology. 11, 9, p. 584-596Research output: Contribution to journal › Literature review
284 Citations (Scopus) -
Narrowband UVB phototherapy for clinically isolated syndrome: Delivering the benefits of all UVB-induced molecules to early MS patients
Kermode, A. G., Hart, P., Lucas, R., Booth, D., Carroll, W., Nolan, D., Cole, J., Jones, A. & Trend, S., 15 Oct 2017, In : Journal of the Neurological Sciences. 381, p. 446Research output: Contribution to journal › Abstract/Meeting Abstract
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Narrowband UVB phototherapy for clinically isolated syndrome: A trial to deliver the benefits of vitamin D and other UVB-induced molecules
Hart, P. H., Lucas, R. M., Booth, D. R., Carroll, W. M., Nolan, D., Cole, J. M., Jones, A. P. & Kermode, A. G., 24 Jan 2017, In : Frontiers in Immunology. 8, January, 3.Research output: Contribution to journal › Article
Open Access16 Citations (Scopus) -
Narrowband UVB phototherapy for Clinically Isolated Syndrome: Delivering the benefits of all UVB-induced molecules to early MS patients
Hart, P., Kermode, A. G., Lucas, R. M., Booth, D. R., Carroll, W. M., Nolan, D., Cole, J. M., Byrne, S. N., Jones, A. P., Trend, S. & Cha, L., Nov 2017, In : Multiple Sclerosis. 23, 13, p. NP7-NP7 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis
Trend, S., Leffler, J., Cooper, M. N., Byrne, S. N., Kermode, A. G., French, M. A. & Hart, P. H., 2020, In : Clinical and Translational Immunology. 9, 10, e1197.Research output: Contribution to journal › Article
Open Access -
PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo
McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Keane, K. N., Newsholme, P., Goodridge, H. S., Zon, L. I., Pixley, F. J. & Hart, P. H., Dec 2017, In : Experimental Hematology. 56, p. 64-68Research output: Contribution to journal › Article
Open AccessFile2 Citations (Scopus)277 Downloads (Pure) -
Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation
Scott, N. M., Ng, R. L. X., McGonigle, T. A., Gorman, S. & Hart, P., Nov 2015, In : Inflammation Research. 64, 11, p. 861-873 13 p.Research output: Contribution to journal › Article
Open AccessFile -
Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice
McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Carter, K. W., Keane, K. N., Newsholme, P., Goodridge, H. S., Pixley, F. J. & Hart, P. H., 1 Jan 2018, In : Journal of Immunology. 200, 1, p. 260-270Research output: Contribution to journal › Article
5 Citations (Scopus) -
Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndrome
Trend, S., Jones, A. P., Cha, L., Cooper, M. N., Geldenhuys, S., Fabis-Pedrini, M. J., Carroll, W. M., Cole, J. M., Booth, D. R., Lucas, R. M., French, M. A., Byrne, S. N., Kermode, A. G. & Hart, P. H., 28 May 2019, In : Scientific Reports. 9, 1, 13 p., 7980.Research output: Contribution to journal › Article
Open Access4 Citations (Scopus) -
Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice
Fleury, N., Feelisch, M., Hart, P. H., Weller, R. B., Smoothy, J., Matthews, V. B. & Gorman, S., 1 Apr 2017, In : Journal of Endocrinology. 233, 1, p. 81-92 12 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
Sun–immune connection
Hart, P. H., Nov 2019, In : Nature Reviews Immunology. 19, 11, p. 661 1 p.Research output: Contribution to journal › Editorial
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The bioenergetics of inflammation: insights into obesity and type 2 diabetes
Keane, K. N., Calton, E. K., Carlessi, R., Hart, P. H. & Newsholme, P., 2017, In : European Journal of Clinical Nutrition. 71, 7, p. 904–912Research output: Contribution to journal › Review article
19 Citations (Scopus) -
The case for greater vigilance in applying sunscreen during real-life sun exposure
Hart, P. H., 1 Mar 2019, In : British Journal of Dermatology. 180, 3, p. 462-463 2 p.Research output: Contribution to journal › Comment/debate
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The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva
Clarke, M. W., Black, L. J., Hart, P. H., Jones, A. P., Palmer, D. J., Siafarikas, A., Lucas, R. M. & Gorman, S., Nov 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 194, 105437.Research output: Contribution to journal › Article
2 Citations (Scopus) -
The changing transcriptome in human skin following in vivo exposure to erythemal solar-simulated ultraviolet radiation
Hart, P. H., 2 Dec 2019, In : British Journal of Dermatology. 1 p.Research output: Contribution to journal › Editorial
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The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function
Foong, R., Bosco, A., Jones, A., Gout, A., Gorman, S., Hart, P. & Zosky, G. R., 1 Nov 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 5, p. 664-675 12 p.Research output: Contribution to journal › Article
Open Access36 Citations (Scopus) -
The Multiple Roles of Urocanic Acid in Health and Disease
Hart, P. H. & Norval, M., 9 Sep 2020, In : Journal of Investigative Dermatology.Research output: Contribution to journal › Review article
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Tracking of Vitamin D status from childhood to early adulthood and its association with peak bone mass
Zhu, K., Oddy, W. H., Holt, P., Ping-Delfos, W. C. S., Mountain, J., Lye, S., Pennell, C., Hart, P. H. & Walsh, J. P., 1 Jul 2017, In : American Journal of Clinical Nutrition. 106, 1, p. 276-283 8 p.Research output: Contribution to journal › Article
Open AccessFile23 Citations (Scopus)211 Downloads (Pure) -
Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis
Cha, L., Jones, A. P., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Carroll, W. M., Lucas, R. M., Cole, J. M., Booth, D. R., Kermode, A. G. & Hart, P. H., 1 Jan 2018, In : Clinical and Translational Immunology. 7, 8, e1037.Research output: Contribution to journal › Article
Open Access4 Citations (Scopus) -
Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice
Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
Ultraviolet radiation, vitamin D and multiple sclerosis
Lucas, R. M., Byrne, S. N., Correale, J., Ilschner, S. & Hart, P. H., 1 Oct 2015, In : Neurodegenerative Disease Management. 5, 5, p. 413-424 12 p.Research output: Contribution to journal › Review article
Open Access40 Citations (Scopus) -
Ultraviolet radiation-induced immunosuppression and its relevance for skin carcinogenesis
Hart, P. H. & Norval, M., 1 Jan 2018, In : Photochemical and Photobiological Sciences. 17, 12, p. 1872-1884 13 p.Research output: Contribution to journal › Review article
26 Citations (Scopus) -
UV Irradiation of Skin Enhances Glycolytic Flux and Reduces Migration Capabilities in Bone Marrow–Differentiated Dendritic Cells
McGonigle, T. A., Keane, K. N., Ghaly, S., Carter, K. W., Anderson, D., Scott, N. M., Goodridge, H. S., Dwyer, A., Greenland, E., Pixley, F. J., Newsholme, P. & Hart, P. H., 1 Sep 2017, In : American Journal of Pathology. 187, 9, p. 2046-2059 14 p.Research output: Contribution to journal › Article
6 Citations (Scopus)