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• A randomised, controlled clinical trial of narrowband UVB phototherapy for clinically isolated syndrome: The PhoCIS study

  Hart, P. H., Jones, A. P., Trend, S., Cha, L., Fabis-Pedrini, M. J., Cooper, M. N., d'Este, C., Geldenhuys, S., Carroll, W. M., Byrne, S. N., Booth, D. R., Cole, J. M., Lucas, R. M. & Kermode, A. G., 22 May 2018, In : Multiple Sclerosis Journal - Experimental, Translational and Clinical. 4, 2, 6 p.

  Research output: Contribution to journal › Article

  Open Access

  • Phototherapy
  • Multiple Sclerosis
  • Randomized Controlled Trials
  • Calcifediol
  • Demyelinating Diseases

• Are there differences in immune responses following delivery of vaccines through acutely or chronically sun-exposed compared with sun-unexposed skin?

  Hart, P. H. & Norval, M., 8 Oct 2019, In : Immunology.

  Research output: Contribution to journal › Review article

  Open Access

  • Solar System
  • Vaccines
  • Skin
  • Ultraviolet Rays
  • Immunization

• Can skin exposure to sunlight prevent liver inflammation?

  Gorman, S., Black, L., Feelisch, M., Hart, P. & Weller, R., 5 May 2015, In : Nutrients. 7, 5, p. 3219-3239

  Research output: Contribution to journal › Review article

  Open Access

  • dermal exposure
  • fatty liver
  • Sunlight
  • vitamin D
  • Non-alcoholic Fatty Liver Disease
  8 Citations (Scopus)

• Cellular and molecular mechanisms of vitamin D in food allergy

  Poole, A., Song, Y., Brown, H., Hart, P. H. & Zhang, G. B., 1 Jul 2018, In : Journal of Cellular and Molecular Medicine. 22, 7, p. 3270-3277 8 p.

  Research output: Contribution to journal › Review article

  Open Access

  • Food Hypersensitivity
  • Vitamin D
  • Microbiota
  • Sunlight
  • DNA Methylation
  8 Citations (Scopus)

• Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation in the mouse: a focus on brown adipose tissue

  Dhamrait, G. K., Panchal, K., Fleury, N. J., Abel, T. N., Ancliffe, M. K., Crew, R. C., Croft, K., Fernandez, B. O., Minnion, M., Hart, P. H., Lucas, R. M., Mark, P. J., Feelisch, M., Weller, R. B., Matthews, V. & Gorman, S., 29 Aug 2019, In : Diabetologia.

  Research output: Contribution to journal › Article

  • Brown Adipose Tissue
  • Ultraviolet Rays
  • Nitric Oxide
  • Uncoupling Protein 1
  • High Fat Diet
  5 Citations (Scopus)

• Comparing the effects of sun exposure and vitamin D supplementation on vitamin D insufficiency, and immune and cardio-metabolic function: The Sun Exposure and Vitamin D Supplementation (SEDS) Study

  Hartley, M., Hoare, S., Lithander, F. E., Neale, R. E., Hart, P., Gorman, S., Gies, P. H. F., Sherriff, J. L., Swaminathan, A., Beilin, L., Mori, T., King, L., Black, L., Marshall, K., Xiang, F., Wyatt, C., King, K., Slevin, T. J., Pandeya, N. & Lucas, R., 2015, In : BMC Public Health. 15, 1, p. 1-9

  Research output: Contribution to journal › Article

  Open Access

  • Solar System
  • Vitamin D
  • Vitamin D Deficiency
  • 25-hydroxyvitamin D
  • Climate
  9 Citations (Scopus)

• Corrigendum to "The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva" [J. Steroid Biochem. Mol. Biol. 194 (2019) 105437]

  Clarke, M. W., Black, L. J., Hart, P. H., Jones, A. P., Palmer, D. J., Siafarikas, A., Lucas, R. M. & Gorman, S., 9 Nov 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 105474.

  Research output: Contribution to journal › Comment/debate

• Cross-presentation of cutaneous melanoma antigen by migratory XCR1⁺CD103⁻ and XCR1⁺CD103⁺ dendritic cells

  Wylie, B., Seppanen, E., Xiao, K., Zemek, R., Zanker, D., Prato, S., Foley, B., Hart, P., Kroczek, R. A., Chen, W. & Waithman, J., 2015, In : OncoImmunology. 4, 8, p. 1-11

  Research output: Contribution to journal › Article

  • Cross-Priming
  • Melanoma-Specific Antigens
  • Dendritic Cells
  • Neoplasm Antigens
  • Skin
  19 Citations (Scopus)

• Dietary Vitamin D Increases Percentages and Function of Regulatory T Cells in the Skin-Draining Lymph Nodes and Suppresses Dermal Inflammation

  Gorman, S., Geldenhuys, S., Judge, M., Weeden, C. E., Waithman, J. & Hart, P. H., 2016, In : Journal of Immunology Research. 2016, 13 p., 1426503.

  Research output: Contribution to journal › Article

  Open Access

  • Regulatory T-Lymphocytes
  • Vitamin D
  • Lymph Nodes
  • Cholecalciferol
  • Inflammation
  6 Citations (Scopus)

• Differences in control by UV radiation of inflammatory airways disease in naïve and allergen pre-sensitised mice

  Scott, N. M., Lambert, M. J. M., Gorman, S., Mcglade, J. P. & Hart, P., 2011, In : Photochemical and Photobiological Sciences. 10, 12, p. 1894-1901

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• Effects of UVR exposure on the gut microbiota of mice and humans

  Ghaly, S., Kaakoush, N. O. & Hart, P. H., 1 Jan 2020, In : Photochemical and Photobiological Sciences. 19, 1, p. 20-28 9 p.

  Research output: Contribution to journal › Review article

  • Ultraviolet radiation
  • radiation dosage
  • mice
  • calciferol
  • radiation
  1 Citation (Scopus)

• Exposure to solar UVR suppresses cell-mediated immunization responses in humans: The Australian Ultraviolet Radiation and Immunity Study

  Swaminathan, A., Harrison, S. L., Ketheesan, N., van den Boogaard, C. H. A., Dear, K., Allen, M., Hart, P. H., Cook, M. & Lucas, R. M., Jul 2019, In : Journal of Investigative Dermatology. 139, 7, p. 1545–1553

  Research output: Contribution to journal › Article

  Open Access

  • Immunization
  • Ultraviolet radiation
  • keyhole-limpet hemocyanin
  • Ultraviolet Rays
  • Clothing
  5 Citations (Scopus)

• Exposure to Ultraviolet Radiation in the Modulation of Human Diseases

  Hart, P. H., Norval, M., Byrne, S. N. & Rhodes, L. E., 1 Jan 2019, In : Annual Review of Pathology: Mechanisms of Disease. 14, p. 55-81 27 p.

  Research output: Contribution to journal › Review article

  • Ultraviolet Rays
  • Radiation Exposure
  • Skin
  • Light
  • Vitiligo
  27 Citations (Scopus)

• Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo

  Calapre, L., Gray, E. S., Kurdykowski, S., David, A., Hart, P., Descargues, P. & Ziman, M., 2016, In : BMC Dermatology. 16, 1, p. 6 6 p.

  Research output: Contribution to journal › Article

  • Keratinocytes
  • Hot Temperature
  • Heat-Shock Response
  • Apoptosis
  • Skin
  14 Citations (Scopus)

• High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

  Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.

  Research output: Contribution to journal › Article

  Open Access

  • Colitis
  • Microbiota
  • Vitamin D
  • Dextran Sulfate
  • Serum Albumin
  18 Citations (Scopus)

• Higher serum immunoglobulin G3 levels may predict the development of multiple sclerosis in individuals with clinically isolated syndrome

  Trend, S., Jones, A. P., Cha, L., Byrne, S. N., Geldenhuys, S., Fabis-Pedrini, M. J., Carroll, W. M., Cole, J. M., Booth, D. R., Lucas, R. M., Kermode, A. G., French, M. A. & Hart, P. H., 13 Jul 2018, In : Frontiers in Immunology. 9, JUL, 1590.

  Research output: Contribution to journal › Article

  Open Access

  • Multiple Sclerosis
  • Immunoglobulins
  • Immunoglobulin G
  • Serum
  • Immunoglobulin M
  10 Citations (Scopus)

• High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease

  Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C., Oct 2016, In : Inflammatory Bowel Diseases. 22, 10, p. 2456-2464 9 p.

  Research output: Contribution to journal › Article

  • Vitamin D-Binding Protein
  • Crohn Disease
  • Albumins
  • Sunlight
  • Recurrence
  11 Citations (Scopus)

• Identification of genes differentially regulated by vitamin D deficiency that alter lung pathophysiology and inflammation in allergic airways disease

  Foong, R. E., Bosco, A., Troy, N. M., Gorman, S., Hart, P. H., Kicic, A. & Zosky, G. R., Sep 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 3, p. L653-L663

  Research output: Contribution to journal › Article

  • Vitamin D Deficiency
  • Pyroglyphidae
  • Pneumonia
  • Smooth Muscle
  • Genes
  7 Citations (Scopus)

• IgG₃ ⁺ B cells are associated with the development of multiple sclerosis

  Marsh-Wakefield, F., Ashhurst, T., Trend, S., McGuire, H. M., Juillard, P., Zinger, A., Jones, A. P., Kermode, A. G., Hawke, S., Grau, G. E., Hart, P. H. & Byrne, S. N., 1 May 2020, In : Clinical and Translational Immunology. 9, 5, e1133.

  Research output: Contribution to journal › Article

  Open Access

  • Multiple Sclerosis
  • B-Lymphocytes
  • B-Lymphocyte Subsets
  • Immunoglobulin G
  • Sclerosis
  3 Citations (Scopus)

• Immune mechanisms by which topically applied vitamin D acts as a therapeutic agent

  Gorman, S. & Hart, P. H., 1 Dec 2011, Vitamin D: Biochemistry, Nutrition and Roles. Nova Science Publishers, p. 167-181 15 p.

  Research output: Chapter in Book/Conference paper › Chapter

  • Vitamin D
  • Keratinocytes
  • Skin Diseases
  • Skin
  • calcipotriene

• Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome

  Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.

  Research output: Contribution to journal › Review article

  • Ultraviolet Rays
  • Microbiota
  • Inflammatory Bowel Diseases
  • Vitamin D
  • Gastrointestinal Microbiome
  1 Citation (Scopus)

• Insufficient sun exposure has become a real public health problem

  Alfredsson, L., Armstrong, B. K., Allan Butterfield, D., Chowdhury, R., de Gruijl, F. R., Feelisch, M., Garland, C. F., Hart, P. H., Hoel, D. G., Jacobsen, R., Lindqvist, P. G., Llewellyn, D. J., Tiemeier, H., Weller, R. B. & Young, A. R., 13 Jul 2020, In : International Journal of Environmental Research and Public Health. 17, 14, p. 1-15 15 p., 5014.

  Research output: Contribution to journal › Review article

  Open Access

  • Public health
  • Medical problems
  • Solar System
  • Sun
  • Public Health
  3 Citations (Scopus)

• Investigating the roles of regulatory T cells, mast cells and interleukin-9 in the control of skin inflammation by vitamin D

  Gorman, S., Geldenhuys, S., Weeden, C., Grimbaldeston, M. A. & Hart, P., 1 Apr 2018, In : Archives of Dermatological Research. 310, 3, p. 221-230 10 p.

  Research output: Contribution to journal › Article

  • Interleukin-9
  • Regulatory T-Lymphocytes
  • Mast Cells
  • Vitamin D
  • Inflammation

• Low-dose UV radiation before running wheel access activates brown adipose tissue

  Allemann, T. S., Dhamrait, G. K., Fleury, N. J., Abel, T. N., Hart, P. H., Lucas, R. M., Matthews, V. B. & Gorman, S., 1 Mar 2020, In : The Journal of Endocrinology. 244, 3, p. 473-486 14 p.

  Research output: Contribution to journal › Article

  Open Access

  • Brown Adipose Tissue
  • Running
  • Ultraviolet Rays
  • High Fat Diet
  • Eating
  1 Citation (Scopus)

• Modulation of the immune system by UV radiation: More than just the effects of vitamin D?

  Hart, P., Gorman, S. & Finlay-Jones, J. J., 2011, In : Nature Reviews Immunology. 11, 9, p. 584-596

  Research output: Contribution to journal › Literature review
  284 Citations (Scopus)

• Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis

  Trend, S., Leffler, J., Cooper, M. N., Byrne, S. N., Kermode, A. G., French, M. A. & Hart, P. H., 2020, In : Clinical and Translational Immunology. 9, 10, e1197.

  Research output: Contribution to journal › Article

  Open Access

  • B-Lymphocyte Subsets
  • Phototherapy
  • Multiple Sclerosis
  • B-Lymphocytes
  • Immunoglobulin D

• Reduced immune responses in chimeric mice engrafted with bone marrow cells from mice with airways inflammation

  Scott, N. M., Ng, R. L. X., McGonigle, T. A., Gorman, S. & Hart, P., Nov 2015, In : Inflammation Research. 64, 11, p. 861-873 13 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Bone Marrow Cells
  • Inflammation
  • Bone Marrow
  • Dendritic Cells
  • Allergens
  254 Downloads (Pure)

• Reticulon-1 and Reduced Migration toward Chemoattractants by Macrophages Differentiated from the Bone Marrow of Ultraviolet-Irradiated and Ultraviolet-Chimeric Mice

  McGonigle, T. A., Dwyer, A. R., Greenland, E. L., Scott, N. M., Carter, K. W., Keane, K. N., Newsholme, P., Goodridge, H. S., Pixley, F. J. & Hart, P. H., 1 Jan 2018, In : Journal of Immunology. 200, 1, p. 260-270

  Research output: Contribution to journal › Article

  • Chemotactic Factors
  • Bone Marrow
  • Macrophages
  • Macrophage Colony-Stimulating Factor
  • Thioglycolates
  5 Citations (Scopus)

• Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults

  Black, L., Burrows, S., Lucas, R. M., Marshall, C., Huang, R-C., Chan She Ping-Delfos, W., Beilin, L., Holt, P., Hart, P., Oddy, W. & Mori, T., Jun 2016, In : British Journal of Nutrition. 115, 11, p. 1994-2002

  Research output: Contribution to journal › Article

  Open Access

  File

  • 25-hydroxyvitamin D
  • Young Adult
  • Serum
  • Insulin Resistance
  • Homeostasis
  12 Citations (Scopus)

  448 Downloads (Pure)

• Short-term changes in frequencies of circulating leukocytes associated with narrowband UVB phototherapy in people with clinically isolated syndrome

  Trend, S., Jones, A. P., Cha, L., Cooper, M. N., Geldenhuys, S., Fabis-Pedrini, M. J., Carroll, W. M., Cole, J. M., Booth, D. R., Lucas, R. M., French, M. A., Byrne, S. N., Kermode, A. G. & Hart, P. H., 28 May 2019, In : Scientific Reports. 9, 1, 13 p., 7980.

  Research output: Contribution to journal › Article

  Open Access
  4 Citations (Scopus)

• Sun–immune connection

  Hart, P. H., Nov 2019, In : Nature Reviews Immunology. 19, 11, p. 661 1 p.

  Research output: Contribution to journal › Editorial

• The case for greater vigilance in applying sunscreen during real-life sun exposure

  Hart, P. H., 1 Mar 2019, In : British Journal of Dermatology. 180, 3, p. 462-463 2 p.

  Research output: Contribution to journal › Comment/debate

  • Sunscreening Agents
  • Solar System

• The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

  Clarke, M. W., Black, L. J., Hart, P. H., Jones, A. P., Palmer, D. J., Siafarikas, A., Lucas, R. M. & Gorman, S., Nov 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 194, 105437.

  Research output: Contribution to journal › Article

  • 25-hydroxyvitamin D
  • Assays
  • Saliva
  • Mastication
  • Blood
  2 Citations (Scopus)

• The changing transcriptome in human skin following in vivo exposure to erythemal solar-simulated ultraviolet radiation

  Hart, P. H., 2 Dec 2019, In : British Journal of Dermatology. 1 p.

  Research output: Contribution to journal › Editorial

• The effects of in utero vitamin D deficiency on airway smooth muscle mass and lung function

  Foong, R., Bosco, A., Jones, A., Gout, A., Gorman, S., Hart, P. & Zosky, G. R., 1 Nov 2015, In : American Journal of Respiratory Cell and Molecular Biology. 53, 5, p. 664-675 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Vitamin D Deficiency
  • Vitamin D
  • Muscle
  • Smooth Muscle
  • Lung
  36 Citations (Scopus)

• The Multiple Roles of Urocanic Acid in Health and Disease

  Hart, P. H. & Norval, M., 9 Sep 2020, In : Journal of Investigative Dermatology.

  Research output: Contribution to journal › Review article

  • Urocanic Acid
  • Skin
  • Health
  • Isomers
  • Atopic Dermatitis

• Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis

  Cha, L., Jones, A. P., Trend, S., Byrne, S. N., Fabis-Pedrini, M. J., Carroll, W. M., Lucas, R. M., Cole, J. M., Booth, D. R., Kermode, A. G. & Hart, P. H., 1 Jan 2018, In : Clinical and Translational Immunology. 7, 8, e1037.

  Research output: Contribution to journal › Article

  Open Access

  • Tryptophan
  • Indoleamine-Pyrrole 2,3,-Dioxygenase
  • Arginase
  • Arginine
  • Multiple Sclerosis
  4 Citations (Scopus)

• Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice

  Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.

  Research output: Contribution to journal › Article

  Open Access

  • vitamin D
  • Microbiota
  • microbiome
  • Vitamin D
  • colitis
  13 Citations (Scopus)

• Ultraviolet radiation, vitamin D and multiple sclerosis

  Lucas, R. M., Byrne, S. N., Correale, J., Ilschner, S. & Hart, P. H., 1 Oct 2015, In : Neurodegenerative Disease Management. 5, 5, p. 413-424 12 p.

  Research output: Contribution to journal › Review article

  Open Access

  • Ultraviolet Rays
  • Vitamin D
  • Multiple Sclerosis
  • Solar System
  • Cellular Immunity
  40 Citations (Scopus)

• Ultraviolet radiation-induced immunosuppression and its relevance for skin carcinogenesis

  Hart, P. H. & Norval, M., 1 Jan 2018, In : Photochemical and Photobiological Sciences. 17, 12, p. 1872-1884 13 p.

  Research output: Contribution to journal › Review article

  • immunosuppression
  • Ultraviolet radiation
  • ultraviolet radiation
  • Skin
  • immune systems
  26 Citations (Scopus)

• UV Irradiation of Skin Regulates a Murine Model of Multiple Sclerosis

  Geldenhuys, S., Mohammad, M. G., Hui, L., Hassanpour, M., Ng, R., Scott, N. M., Lucas, R., Brown, D. A. & Hart, P., 2015, In : Journal of Multiple Sclerosis. 2, 3, p. 1-5

  Research output: Contribution to journal › Article

  Open Access

• Vitamin D and allergic airway disease shape the murine lung microbiome in a sex-specific manner

  Roggenbuck, M., Anderson, D., Barfod, K. K., Feelisch, M., Geldenhuys, S., Sørensen, S. J., Weeden, C. E., Hart, P. H. & Gorman, S., 2016, In : Respiratory Research. 17, 1, p. 116 116 p.

  Research output: Contribution to journal › Article

  Open Access

  • Microbiota
  • Vitamin D
  • Lung
  • Diet
  • Ovalbumin
  13 Citations (Scopus)

• Vitamin D and atopy and asthma phenotypes in children: A longitudinal cohort study

  Hollams, E., Hart, P., Holt, B. J., Serralha, M., Parsons, F., De Klerk, N., Zhang, B., Sly, P. D. & Holt, P., 2011, In : European Respiratory Journal. 38, 6, p. 1320-1327

  Research output: Contribution to journal › Article
  134 Citations (Scopus)

• Vitamin D C3-epimer levels are proportionally higher with oral vitamin D supplementation compared to ultraviolet irradiation of skin in mice but not humans

  Ghaly, S., Bliuc, D., Centre, J., Clarke, M. W., Jones, A. P., Trend, S., Kermode, A. G., Neale, R. E. & Hart, P. H., 1 Feb 2019, In : The Journal of Steroid Biochemistry and Molecular Biology. 186, p. 110-116

  Research output: Contribution to journal › Article

  • Cholecalciferol
  • Irradiation
  • Vitamin D
  • Skin
  • Ultraviolet radiation
  3 Citations (Scopus)

• Vitamin D deficiency causes deficits in lung function and alters lung structure

  Zosky, G., Berry, L. J., Elliot, J. G., James, A. L., Gorman, S. & Hart, P., 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 10, p. 1336-1343

  Research output: Contribution to journal › Article
  237 Citations (Scopus)

• Vitamin D in fetal development: Findings from a birth cohort study

  Hart, P., Lucas, R., Walsh, J., Zosky, G., Whitehouse, A., Zhu, K., Allen, K., Kusel, M. M., Anderson, D. & Mountain, J., 2015, In : Pediatrics. 135, 1, p. e167-e173

  Research output: Contribution to journal › Article
  61 Citations (Scopus)

• Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission

  Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.

  Research output: Contribution to journal › Article

  Open Access

  • Crohn Disease
  • Vitamin D
  • Vitamin D-Binding Protein
  • Inflammation
  • 25-hydroxyvitamin D