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• ABCA1 and placental cholesterol efflux

  Keelan, J., Aye, I., Mark, P. & Waddell, B., 2011, In : Placenta. 32, p. 708-709

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• A Critical Review of the Bacterial Baptism Hypothesis and the Impact of Cesarean Delivery on the Infant Microbiome

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2018, In : Frontiers of Medicine. 5, 135.

  Research output: Contribution to journal › Review article

  Open Access

  • Microbiota
  • Obesity
  • Dysbiosis
  • Noncommunicable Diseases
  • Maternal Age
  46 Citations (Scopus)

• Adult digit ratio (2D:4D) is not related to umbilical cord androgen or estrogen concentrations, their ratios or net bioactivity

  Hollier, L. P., Keelan, J., Jamnadass, E., Maybery, M., Hickey, M. & Whitehouse, A., Feb 2015, In : Early Human Development. 91, 2, p. 111-117 7 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Umbilical Cord
  • Androgens
  • Estrogens
  • Fetal Blood
  • Testosterone
  38 Citations (Scopus)

  505 Downloads (Pure)

• Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

  Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

  Research output: Book/Report › Edited book/Anthology

• Androgen concentrations in umbilical cord blood and their association with maternal, fetal and obstetric factors

  Keelan, J., Mattes, E., Tan, H., Dinan, A., Newnham, J., Whitehouse, A., Jacoby, P. & Hickey, M., 20 Aug 2012, In : PLoS One. 7, 8, p. e42827.1-10

  Research output: Contribution to journal › Article

  Open Access

  • Fetal Blood
  • Androgens
  • Obstetrics
  • Testosterone
  • Mothers
  54 Citations (Scopus)

• A new, potent, and placenta-permeable macrolide antibiotic, solithromycin, for the prevention and treatment of bacterial infections in pregnancy

  Keelan, J., Payne, M., Kemp, M., Ireland, D. & Newnham, J., 1 Apr 2016, In : Frontiers in Immunology. 7, p. 1-11 11 p., 111.

  Research output: Contribution to journal › Review article

  Open Access

  • solithromycin
  • Macrolides
  • Bacterial Infections
  • Placenta
  • Anti-Bacterial Agents
  15 Citations (Scopus)

• Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny

  Beaudry-Richard, A., Nadeau-Vallée, M., Prairie, É., Maurice, N., Heckel, É., Nezhady, M., Pundir, S., Madaan, A., Boudreault, A., Hou, X., Quiniou, C., Sierra, E. M., Beaulac, A., Lodygensky, G., Robertson, S. A., Keelan, J., Adams-Waldorf, K., Olson, D. M., Rivera, J. C., Lubell, W. D. & 3 others, Joyal, J. S., Bouchard, J. F. & Chemtob, S., 8 Aug 2018, In : Scientific Reports. 8, 1, 11875.

  Research output: Contribution to journal › Article

  Open Access

  • Interleukin-1
  • Inflammation
  • Chorioamnionitis
  • Hyperoxia
  • Retinal Vessels
  9 Citations (Scopus)

• A specific bacterial DNA signature in the vagina of Australian women in midpregnancy predicts high risk of spontaneous preterm birth (the Predict1000 study)

  Payne, M. S., Newnham, J. P., Doherty, D. A., Furfaro, L. L., Pendal, N. L., Loh, D. E. & Keelan, J. A., 27 Aug 2020, In : American Journal of Obstetrics and Gynecology.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Vagina
  • Premature Birth
  • Ureaplasma
  • Lactobacillus
  1 Citation (Scopus)

• Ceramide biosynthesis and metabolism in trophoblast syncytialization

  Singh, A. T., Dharmarajan, A., Aye, I. & Keelan, J., 2012, In : Molecular and Cellular Endocrinology. 362, p. 48 - 59

  Research output: Contribution to journal › Article
  11 Citations (Scopus)

• Changes in inflammatory mediators in gingival crevicular fluid following periodontal disease treatment in pregnancy: relationship to adverse pregnancy outcome

  Penova-Veselinovic, B., Keelan, J., Wang, C., Newnham, J. & Pennell, C., Nov 2015, In : Journal of Reproductive Immunology. 112, p. 1-10 10 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Gingival Crevicular Fluid
  • Periodontal Diseases
  • Pregnancy Outcome
  • Pregnancy
  • Interleukin-1
  17 Citations (Scopus)

  376 Downloads (Pure)

• Characterization of the bacterial microbiome in first-pass meconium using propidium monoazide (PMA) to exclude nonviable bacterial DNA

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 May 2019, In : Letters in Applied Microbiology. 68, 5, p. 378-385 8 p.

  Research output: Contribution to journal › Article

  • propidium monoazide
  • Meconium
  • Bacterial DNA
  • Microbiota
  • Cell-Free Nucleic Acids
  7 Citations (Scopus)

• Comparison of Bacterial DNA Profiles in Mid-Trimester Amniotic Fluid Samples From Preterm and Term Deliveries

  Stinson, L., Hallingström, M., Barman, M., Viklund, F., Keelan, J., Kacerovsky, M., Payne, M. & Jacobsson, B., 24 Mar 2020, In : Frontiers in Microbiology. 11, 415.

  Research output: Contribution to journal › Article

  Open Access

  • Bacterial DNA
  • Amniotic Fluid
  • rRNA Genes
  • DNA Contamination
  • Technology
  4 Citations (Scopus)

• Comparison of Meconium DNA extraction methods for use in microbiome studies

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 20 Feb 2018, In : Frontiers in Microbiology. 9, FEB, 270.

  Research output: Contribution to journal › Article

  Open Access

  • Meconium
  • Microbiota
  • DNA
  • Bacterial DNA
  • Polymerase Chain Reaction
  16 Citations (Scopus)

• Decreased STAT3 in human idiopathic fetal growth restriction contributes to trophoblast dysfunction

  Borg, A. J., Yong, H. E. J., Lappas, M., Degrelle, S. A., Keogh, R. J., Da Silva-Costa, F., Fournier, T., Abumaree, M., Keelan, J., Kalionis, B. & Murthi, P., 1 May 2015, In : Reproduction. 149, 5, p. 523-532

  Research output: Contribution to journal › Article

  • Fetal Growth Retardation
  • Trophoblasts
  • STAT3 Transcription Factor
  • Placenta
  • Caspase 8
  15 Citations (Scopus)

• Development of a model for functional studies of ABCG2 (breast cancer resistance protein) efflux employing a standard BeWo clone (B24)

  Keelan, J. & Crowe, A., 2012, In : Assay and Drug Development Technologies. 10, p. 476 - 484

  Research output: Contribution to journal › Article
  4 Citations (Scopus)

• Drugs to block cytokine signaling for the prevention and treatment of inflammation induced preterm birth

  Ng, P. Y., Ireland, D. & Keelan, J., 20 Apr 2015, In : Frontiers in Immunology. 6, p. 1-8

  Research output: Contribution to journal › Article

  Open Access

  • Premature Birth
  • Cytokines
  • Inflammation
  • Anti-Inflammatory Agents
  • Pharmaceutical Preparations
  38 Citations (Scopus)

• Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

  Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

  Research output: Contribution to journal › Article

  Open Access

  File

  • Spermatozoa
  • Fetal Development
  • Fetal Blood
  • Parturition
  • Estrone
  10 Citations (Scopus)

  286 Downloads (Pure)

• Editorial: Advances in the prevention and treatment of inflammation-associated preterm birth

  Keelan, J. A. & Newnham, J. P., 2016, In : Frontiers in Immunology. 7, JUN, p. 5-6 2 p.

  Research output: Contribution to journal › Letter

  Open Access
  4 Citations (Scopus)

• Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy

  Yang, H., Sun, C., Fan, Z., Tian, X., Yan, L., Du, L., Liu, Y., Chen, C., Liang, X., Anderson, GJ., Keelan, J., Zhao, Y. & Nie, G., 2012, In : Scientific Reports. 2, p. 847 - 854

  Research output: Contribution to journal › Article

  Open Access
  88 Citations (Scopus)

• Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

  Keelan, J., Mas, E., D'Vaz, N., Dunstan, J., Li, S., Barden, A., Mark, P., Waddell, B., Prescott, S. & Mori, T., 1 Feb 2015, In : Reproduction. 149, p. 171-178 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Omega-3 Fatty Acids
  • Docosahexaenoic Acids
  • Lipids
  • Mothers
  • Cytokines
  51 Citations (Scopus)

• Effects of omega-3 and omega-6 fatty acids on human placental cytokine production

  Melody, S. M., Vincent, R., Mori, T., Mas, E., Barden, A., Waddell, B. & Keelan, J., 2015, In : Placenta. 36, 1, p. 34-40

  Research output: Contribution to journal › Article

  • Omega-6 Fatty Acids
  • Omega-3 Fatty Acids
  • Cytokines
  • Placenta
  • Fatty Acids
  9 Citations (Scopus)

• Fetal Testosterone, Socio-Emotional Engagement and Language Development

  Farrant, B., Mattes, E., Keelan, J., Hickey, M. & Whitehouse, A., 2013, In : Infant and Child Development. 22, 2, p. 119-132

  Research output: Contribution to journal › Article
  9 Citations (Scopus)

• Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

  Chui, A., Evseenko, D. A., Brennecke, S. P., Keelan, J., Kalionis, B. & Murthi, P., 2011, In : Placenta. 32, p. 745-751

  Research output: Contribution to journal › Article
  15 Citations (Scopus)

• Identification and removal of contaminating microbial DNA from PCR reagents: impact on low-biomass microbiome analyses

  Stinson, L. F., Keelan, J. A. & Payne, M. S., 1 Jan 2019, In : Letters in Applied Microbiology. 68, 1, p. 2-8 7 p.

  Research output: Contribution to journal › Article

  • Biomass
  • Microbiota
  • Polymerase Chain Reaction
  • DNA
  • DNA Contamination
  21 Citations (Scopus)

• IFPA meeting 2015 workshop report III: nanomedicine applications and exosome biology, xenobiotics and endocrine disruptors and pregnancy, and lipid

  Albrecht, C., Caniggia, I., Clifton, V., Göhner, C., Harris, L., Hemmings, D., Jawerbaum, A., Johnstone, E., Jones, H., Keelan, J., Lewis, R., Mitchell, M., Murthi, P., Powell, T., Saffery, R., Smith, R., Vaillancourt, C., Wadsack, C. & Salomon, C., 2016, In : Placenta. 48, p. S12-S16

  Research output: Contribution to journal › Article

  • Nanomedicine
  • Endocrine Disruptors
  • Exosomes
  • Xenobiotics
  • Lipids
  4 Citations (Scopus)

• Inflammation of the Fetal Ovine Skin Following in utero Exposure to Ureaplasma parvum

  Kemp, M., Saito, M., Kallapur, S., Jobe, A., Keelan, J., Li, S., Kramer, B. W., Zhang, L., Knox, C., Yaegashi, N. & Newnham, J., 2011, In : Reproductive Sciences. 18, 11, p. 1128-37

  Research output: Contribution to journal › Article
  26 Citations (Scopus)

• Intra-amniotic pharmacological blockade of inflammatory signalling pathways in an ovine chorioamnionitis model

  Ireland, D., Kemp, M., Miura, Y., Saito, M., Newnham, J. & Keelan, J., May 2015, In : Molecular Human Reproduction. 21, 5, p. 479-489

  Research output: Contribution to journal › Article

  Open Access

  File

  • Chorioamnionitis
  • Sheep
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • Lipopolysaccharides
  • Pharmacology
  25 Citations (Scopus)

  252 Downloads (Pure)

• Intracellular speciation of gold nanorods alters the conformational dynamics of genomic DNA

  Ho, D., Kretzmann, J., Norret, M., Toshniwal, P., Veder, J. P., Jiang, H., Guagliardo, P., Munshi, A. M. A., Chawla, R., Evans, C., Clemons, T., Nguyen, M., Kretzmann, A., Blythe, A., Saunders, M., Archer, M., Fitzgerald, M., Keelan, J., Bond, C., Kilburn, M. & 3 others, Hurley, L., Smith, N. & Swaminatha Iyer, K., Dec 2018, In : Nature Nanotechnology. 13, 2

  Research output: Contribution to journal › Article

  • Nanorods
  • Gold
  • DNA
  • nanorods
  • deoxyribonucleic acid
  6 Citations (Scopus)

• Intrauterine inflammatory activation, functional progesterone withdrawal, and the timing of term and preterm birth

  Keelan, J. A., Feb 2018, In : Journal of Reproductive Immunology. 125, p. 89-99 11 p.

  Research output: Contribution to journal › Review article
  42 Citations (Scopus)

• In vitro activity of solithromycin and its metabolites, CEM-214 and N-acetyl-CEM-101, against 100 clinical Ureaplasma spp. isolates compared with azithromycin

  Furfaro, L., Spiller, O. B., Keelan, J. & Payne, M., Sep 2015, In : International Journal of Antimicrobial Agents. 46, 3, p. 319-324

  Research output: Contribution to journal › Article

  Open Access

  File

  • solithromycin
  • Ureaplasma
  • Azithromycin
  • In Vitro Techniques
  12 Citations (Scopus)

  266 Downloads (Pure)

• In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes.

  Walls, M., Hunter, T., Ryan, J., Keelan, J., Nathan, L. & Hart, R., 2015, In : Human Reproduction. 30, p. 88-96

  Research output: Contribution to journal › Article
  79 Citations (Scopus)

• In vitro maturation is associated with increased early embryo arrest without impairing morphokinetic development of useable embryos progressing to blastocysts

  Walls, M., Ryan, J., Keelan, J. & Hart, R., 2015, In : Human Reproduction. 30, 8, p. 1842-1849

  Research output: Contribution to journal › Article

  • Blastocyst
  • Polycystic Ovary Syndrome
  • Embryonic Development
  • Intracytoplasmic Sperm Injections
  • Embryonic Structures
  21 Citations (Scopus)

• Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep

  Keelan, J., Nitsos, I., Saito, M., Musk, G., Kemp, M., Timmins, M., Li, S., Yaegashi, N. & Newnham, J., 2011, In : American Journal of Obstetrics and Gynecology. 204, p. 10-17

  Research output: Contribution to journal › Article
  16 Citations (Scopus)

• Maternal dietary omega-3 fatty acid intake increases resolvin and protectin levels in the rat placenta

  Jones, M., Mark, P., Keelan, J., Barden, A., Mas, E., Mori, T. & Waddell, B., Aug 2013, In : Journal of Lipid Research. 54, p. 2247-2254

  Research output: Contribution to journal › Article

  Open Access
  40 Citations (Scopus)

• Maternal Dietary Omega-3 Fatty Acid Supplementation Reduces Placental Oxidative Stress and Increases Fetal and Placental Growth in the Rat

  Jones, M., Mark, P., Mori, T., Keelan, J. & Waddell, B., 1 Feb 2013, In : Biology of Reproduction. 88, 2, p. 1-8

  Research output: Contribution to journal › Article

  Open Access
  54 Citations (Scopus)

• Maternal perinatal depression, circulating oxytocin levels and childhood emotional disorders at 4 years of age: The importance of psychosocial context

  Galbally, M., Watson, S. J., Keelan, J., MacMillan, K. K., Power, J., IJzendoorn, M. V. & Lewis, A. J., Nov 2020, In : Journal of Psychiatric Research. 130, p. 247-253 7 p.

  Research output: Contribution to journal › Article

  • Oxytocin
  • Depression
  • Mothers
  • Pregnancy
  • Postpartum Period

• Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation

  Yang, H., Du, L., Wu, G., Wu, Z. & Keelan, J. A., 3 Dec 2018, In : Molecular Medicine. 24, 16 p., 62.

  Research output: Contribution to journal › Article

  Open Access
  8 Citations (Scopus)

• Nanoparticulate drug delivery in pregnancy: Placental passage and fetal exposure

  Menezes, V., Malek, A. & Keelan, J., 2011, In : Current Pharmaceutical Biotechnology. 12, p. 731-742

  Research output: Contribution to journal › Article
  43 Citations (Scopus)

• Nanotoxicology: Nanoparticles versus the placenta

  Keelan, J., 2011, In : Nature Nanotechnology. 6, p. 263-264

  Research output: Contribution to journal › Review article

  48 Citations (Scopus)

• Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-kB

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2012, In : Molecular Human Reproduction. 18, 7, p. 341 - 353

  Research output: Contribution to journal › Article
  47 Citations (Scopus)

• Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors

  Aye, I., Waddell, B., Mark, P. & Keelan, J., 2011, In : Placenta. 32, p. 183-191

  Research output: Contribution to journal › Article
  28 Citations (Scopus)

• Paracrine communication modulates production of Wnt antagonists and COX1-mediated prostaglandins in a decidual-trophoblast co-culture model

  Bin Nayeem, S., Dharmarajan, A. & Keelan, J., 2015, In : Molecular and Cellular Endocrinology. 405, p. 52–62

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• Perinatal testosterone exposure and autistic-like traits in the general population: a longitudinal pregnancy-cohort study

  Whitehouse, A., Mattes, E., Maybery, M., Dissanayake, C., Sawyer, M., Jones, R., Pennell, C., Keelan, J. & Hickey, M., 30 Oct 2012, In : Journal of Neurodevelopmental Disorders. 4, p. 25pp

  Research output: Contribution to journal › Article

  Open Access

  • Testosterone
  • Cohort Studies
  • Pregnancy
  • Fetal Blood
  • Population
  40 Citations (Scopus)

• Pharmacological inhibition of inflammatory pathways for the prevention of preterm birth

  Keelan, J., 2011, In : Journal of Reproductive Immunology. 88, p. 176-184

  Research output: Contribution to journal › Article
  30 Citations (Scopus)

• Placental ABC transporters, cellular toxicity and stress in pregnancy

  Aye, I. L. M. H. & Keelan, J., 2013, In : Chemico-Biological Interactions. 203, p. 456-466

  Research output: Contribution to journal › Review article
  32 Citations (Scopus)

• Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

  Stinson, L., Payne, M. & Keelan, J., Sep 2019, In : Placenta. 85, p. 12-23

  Research output: Contribution to journal › Article

  • Parturition
  • cyclic guanosine monophosphate-adenosine monophosphate
  • Inflammation
  • Poly I-C
  • resiquimod
  3 Citations (Scopus)

• Planting the seed: Origins, composition, and postnatal health significance of the fetal gastrointestinal microbiota

  Stinson, L. F., Payne, M. S. & Keelan, J. A., 2016, In : Critical Reviews in Microbiology. 43, 3, p. 352-369 18 p.

  Research output: Contribution to journal › Review article

  • Seeds
  • Microbiota
  • Gastrointestinal Microbiome
  • Health
  • Extraembryonic Membranes
  59 Citations (Scopus)

• Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

  Whitehouse, A., Gilani, Z., Shafait, F., Mian, A., Tan, D., Maybery, M., Keelan, J., Hart, R., Handelsman, D. J., Goonawardene, M. & Eastwood, P., 7 Oct 2015, In : Proceedings of the Royal Society B: Biological Sciences. 282, 1816, p. 1-9 9 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • testosterone
  • adulthood
  • Testosterone
  • exposure
  • Femininity
  77 Citations (Scopus)

  843 Downloads (Pure)

• Profiling bacterial communities in low biomass samples: Pitfalls and considerations

  Stinson, L. F., Keelan, J. A. & Payne, M. S., Nov 2019, In : Microbiology Australia. 40, 4, p. 181-185 5 p.

  Research output: Contribution to journal › Review article

  • Biomass
  • Workflow
  • rRNA Genes
  • Built Environment
  • Meconium
  3 Citations (Scopus)

• Prospective study of the association between in-utero exposures to circulating maternal phthalate metabolites and timing of menarche

  Hart, R., Nathan, E., Doherty, D., Frederiksen, H., Keelan, J., Skakkebaek, N., Hickey, M., Newnham, J. & Main, K., Jul 2019, In : Human Reproduction. 34, p. 398-399 2 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract