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  • Markus Schlaich

Opposing effects of shear-mediated dilation and myogenic constriction on artery diameter in response to handgrip exercise in humans

Atkinson, C., Carter, H., Naylor, L., Dawson, E. A., Marusic, P., Hering, D., Schlaich, M., Thijssen, D. H. J. & Green, D. J., 15 Oct 2015, In : Journal of Applied Physiology. 119, 8, p. 858-864 7 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
339 Downloads (Pure)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

423 Citations (Scopus)

Percutaneous transluminal renal denervation: A potential treatment option for polycystic kidney disease-related pain?

Shetty, S., Roberts, T. J. & Schlaich, M. P., 2013, In : International Journal of Cardiology. 162, 3, p. e58-e59

Research output: Contribution to journalLetter

18 Citations (Scopus)

Pharmacotherapeutic strategies for treating hypertension in patients with obesity

Carnagarin, R., Matthews, V., Gregory, C. & Schlaich, M. P., 3 May 2018, In : Expert Opinion on Pharmacotherapy. 19, 7, p. 643-651 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Pioglitazone treatment enhances the sympathetic nervous system response to oral carbohydrate load in obese individuals with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Richards, K., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Jul 2015, In : Metabolism: clinical and experimental. 64, 7, p. 797-803 7 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

Esler, M., Lambert, E. & Schlaich, M., Dec 2010, In : Journal of Applied Physiology. 109, 6, p. 1996-1998 3 p.

Research output: Contribution to journalArticle

85 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Preferred Fourth-Line Pharmacotherapy for Resistant Hypertension: Are We There Yet?

Prosser, H. C., Gregory, C., Hering, D., Hillis, G. S., Perry, G., Rosman, J., Schultz, C., Thomas, M., Watts, G. F. & Schlaich, M. P., 1 Apr 2017, In : Current Hypertension Reports. 19, 4, 30.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Rationale and design of a large registry on renal denervation: The Global SYMPLICITY registry

Böhm, M., Mahfoud, F., Ukena, C., Bauer, A., Fleck, E., Hoppe, U. C., Kintscher, U., Narkiewicz, K., Negoita, M., Ruilope, L., Rump, L. C., Schlaich, M., Schmieder, R., Sievert, H., Weil, J., Williams, B., Zeymer, U. & Mancia, G., Aug 2013, In : EuroIntervention. 9, 4, p. 484-492 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Rebuttal from Esler, Lambert, and Schlaich.

Esler, M., Lambert, E. & Schlaich, M., 2010, In : Journal of applied physiology (Bethesda, Md. : 1985). 109, 6, p. 2000-2001 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Rebuttal from Markus P. Schlaich, Yusuke Sata and Murray D. Esler

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Recent advances in the treatment of hypertension

Hering, D., Esler, M. D., Krum, H., Mahfoud, F., Böhm, M., Sobotka, P. A. & Schlaich, M. P., 1 Jun 2011, In : Expert Review of Cardiovascular Therapy. 9, 6, p. 729-744 16 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Recurrent postural vasovagal syncope: Sympathetic nervous system phenotypes

Vaddadi, G., Guo, L., Esler, M., Socratous, F., Schlaich, M., Chopra, R., Eikelis, N., Lambert, G., Trauer, T. & Lambert, E., Oct 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Reduction in basal nitric oxide activity causes albuminuria

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. & Schmieder, R. E., Feb 2011, In : Diabetes. 60, 2, p. 572-576 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Reduction in blood pressure following renal denervation for patients with differing baseline cardiovascular risk

Mahfoud, F., Mancia, G., Schmieder, R., Narkiewicz, K., Ruilope, L., Schlaich, M., Williams, B., Fahy, M. & Bohm, M., Oct 2019, In : European Heart Journal. 40, p. 663-663 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

10 Citations (Scopus)

Reduction in peripheral vascular resistance predicts improvement in insulin clearance following weight loss

Straznicky, N. E., Grima, M. T., Sari, C. I., Lambert, E. A., Phillips, S. E., Eikelis, N., Kobayashi, D., Hering, D., Mariani, J. A., Dixon, J. B., Nestel, P. J., Karapanagiotidis, S., Schlaich, M. P. & Lambert, G. W., 22 Aug 2015, In : Cardiovascular Diabetology. 14, 1, 113.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Regulation of the sympathetic nervous system by the kidney

Larsen, R., Thorp, A. & Schlaich, M., 2014, In : Current Opinion in Nephrology and Hypertension. 23, 1, p. 61-68 8 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Reinnervation following catheter-based radio-frequency renal denervation

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 20 Apr 2015, In : Experimental Physiology. 100, 5, p. 485-490 6 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Reinnervation of renal afferent and efferent nerves at 5.5 and 11 months after catheter-based radiofrequency renal denervation in sheep

Booth, L. C., Nishi, E. E., Yao, S. T., Ramchandra, R., Lambert, G. W., Schlaich, M. P. & May, C. N., 21 Feb 2015, In : Hypertension. 65, 2, p. 393-400 8 p.

Research output: Contribution to journalArticle

Open Access
79 Citations (Scopus)

Relation between QT interval variability and cardiac sympathetic activity in hypertension

Baumert, M., Schlaich, M. P., Nalivaiko, E., Lambert, E., Sari, C. I., Kaye, D. M., Elser, M. D., Sanders, P. & Lambert, G., Apr 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 4

Research output: Contribution to journalArticle

70 Citations (Scopus)

Relevance of sympathetic nervous system activation in obesity and metabolic syndrome

Thorp, A. A. & Schlaich, M., 2015, In : Journal of Diabetes Research. 2015, p. 1-11

Research output: Contribution to journalArticle

Open Access
File
138 Citations (Scopus)
206 Downloads (Pure)
Open Access

Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension

Lauder, L., Ewen, S., Tzafriri, A. R., Edelman, E. R., Lüscher, T. F., Blankestijn, P. J., Dörr, O., Schlaich, M., Sharif, F., Voskuil, M., Zeller, T., Ukena, C., Scheller, B., Böhm, M. & Mahfoud, F., 1 May 2018, In : EuroIntervention. 14, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Renal artery denervation for treatment of patients with self-reported obstructive sleep apnea and resistant hypertension: Results from the Global SYMPLICITY Registry

Linz, D., Mancia, G., Mahfoud, F., Narkiewicz, K., Ruilope, L., Schlaich, M., Kindermann, I., Schmieder, R. E., Ewen, S., Williams, B. & Bohm, M., 2017, In : Journal of Hypertension. 35, 1, p. 148-153 6 p.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Renal artery radiofrequency ablation for refractory hypertension

Schlaich, M., 2010, In : Cardiology in General Practice. 113, p. 16-18

Research output: Contribution to journalReview article

Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves

Hennebry, S. C., Eikelis, N., Socratous, F., Desir, G., Lambert, G. & Schlaich, M., Mar 2010, In : Molecular Psychiatry. 15, 3, p. 234-236 3 p.

Research output: Contribution to journalLetter

Open Access
62 Citations (Scopus)

Renalase - A potential biomarker for risk of atrial fibrillation?

Schlaich, M. P., Lambert, G. W. & Eikelis, N., 14 Aug 2018, In : Kardiologia Polska. 76, 8, p. 1201-1202 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Citation (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Renal denervation: Current opinions and practice

Schlaich, M. P., 31 Jul 2017, Cardio-Nephrology: Confluence of the Heart and Kidney in Clinical Practice. USA: Springer International Publishing AG, p. 419-426 8 p.

Research output: Chapter in Book/Conference paperChapter

Renal denervation: one step backwards, three steps forward

Schlaich, M. P. & Bakris, G. L., Oct 2018, In : Nature Reviews Nephrology. 14, 10, p. 602-604 2 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Renal denervation: A potential new treatment modality for polycystic ovary syndrome?

Schlaich, M. P., Straznicky, N., Grima, M., Ika-Sari, C., Dawood, T., Mahfoud, F., Lambert, E., Chopra, R., Socratous, F., Hennebry, S., Eikelis, N., Böhm, M., Krum, H., Lambert, G., Esler, M. D. & Sobotka, P. A., May 2011, In : Journal of Hypertension. 29, 5, p. 991-996 6 p.

Research output: Contribution to journalArticle

130 Citations (Scopus)

Renal denervation: A new approach to treatment of resistant hypertension

Heuser, R. R. (ed.), Schlaich, M. (ed.) & Sievert, H. (ed.), 2015, New York: Springer-Verlag London Ltd. 201 p.

Research output: Book/ReportBook

Renal denervation: Potential future implications beyond resistant hypertension

Schlaich, M. P., 2015, Renal Denervation: A New Approach to Treatment of Resistant Hypertension. New York: Springer-Verlag London Ltd., p. 155-161 7 p.

Research output: Chapter in Book/Conference paperChapter

Renal Denervation After the SPYRAL HTN-OFF MED Trial Putting a Complex Study Into Context

Schlaich, M. P. & Esler, M. D., Dec 2017, In : Hypertension. 70, 6, p. 1076-1079 4 p.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

Renal denervation and hypertension

Schlaich, M. P., Krum, H., Sobotka, P. A. & Esler, M. D., Jun 2011, In : American Journal of Hypertension. 24, 6, p. 635-642 8 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)

Renal denervation and pulmonary vein isolation in patients with drug resistant hypertension and symptomatic atrial fibrillation

Wilson, S., Kistler, P. M., Mclellan, A. J. A., Hering, D. & Schlaich, M., 2014, In : JOURNAL OF ATRIAL FIBRILLATION. 7, 4, p. 69-74

Research output: Contribution to journalReview article

1 Citation (Scopus)

Renal denervation for resistant hypertension—the Symplicity HTN-1 study – Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 1 May 2014, In : The Lancet. 383, 9932, p. 1885-1886

Research output: Contribution to journalLetter

Renal Denervation for Treating Hypertension Current Scientific and Clinical Evidence

Weber, M. A., Mahfoud, F., Schmieder, R. E., Kandzari, D. E., Tsioufis, K. P., Townsend, R. R., Kario, K., Bohm, M., Sharp, A. S. P., Davies, J. E., Osborn, J. W., Fink, G. D., Euler, D. E., Cohen, D. L., Schlaich, M. P. & Esler, M. D., 24 Jun 2019, In : JACC: Cardiovascular Interventions. 12, 12, p. 1095-1105 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Renal denervation in less severe forms of (resistant) hypertension—Quo vadis?

Schlaich, M. P., Hering, D. & Sata, Y., 1 Apr 2017, In : Journal of Clinical Hypertension. 19, 4, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

Renal DenervationReady for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M. P., Kiuchi, M. G. & Esler, M. D., Aug 2018, In : Hypertension. 72, 2, p. 287-290 4 p.

Research output: Contribution to journalEditorial

5 Citations (Scopus)

Renal Denervation - Ready for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M., Galindo Kiuchi, M. & Esler, M. D., Aug 2018, In : Hypertension. 72, p. 287–290

Research output: Contribution to journalEditorial

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

Zaldivia, M. T. K., Rivera, J., Hering, D., Marusic, P., Sata, Y., Lim, B., Eikelis, N., Lee, R., Lambert, G. W., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Eisenhardt, S. U., Flierl, U., Schlaich, M. P. & Peter, K., 1 Feb 2017, In : Hypertension. 69, 2, p. 323-331 9 p.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
223 Downloads (Pure)

Renal Denervation Update From the International Sympathetic Nervous System Summit

Kiuchi, M. G., Esler, M. D., Fink, G. D., Osborn, J. W., Banek, C. T., Boehm, M., Denton, K. M., DiBona, G. F., Everett, T. H., Grassi, G., Katholi, R. E., Knuepfer, M. M., Kopp, U. C., Lefer, D. J., Lohmeier, T. E., May, C. N., Mahfoud, F., Paton, J. F. R., Schmieder, R. E., Pellegrino, P. R. & 2 others, Sharabi, Y. & Schlaich, M. P., 18 Jun 2019, In : Journal of the American College of Cardiology. 73, 23, p. 3006-3017 12 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Renal sympathetic denervation: a viable option for treating resistant hypertension

Schlaich, M. P., Sep 2017, In : American Journal of Hypertension. 30, 9, p. 847-856 10 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Renal Sympathetic Denervation

Schlaich, M., 2015, Chronic Kidney Disease and Hypertension. Weir, M. R. & Lerma, E. V. (eds.). New York: Humana Press, p. 69-81

Research output: Chapter in Book/Conference paperChapter

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

Esler, M. D., Krum, H., Sobotka, P. A., Schlaich, M. P., Schmieder, R. E., Böhm, M., Mahfoud, F., Sievert, H., Wunderlich, N., Rump, L. C., Vonend, O., Uder, M., Lobo, M., Caulfield, M., Erglis, A., Azizi, M., Sapoval, M., Thambar, S., Persu, A., Renkin, J. & 24 others, Schunkert, H., Weil, J., Hoppe, U. C., Walton, T., Scheinert, D., Binder, T., Januszewicz, A., Witkowski, A., Ruilope, L. M., Whitbourn, R., Bruck, H., Downes, M., Lüscher, T. F., Jardine, A. G., Webster, M. W., Zeller, T., Sadowski, J., Bartus, K., Straley, C. A., Barman, N. C., Lee, D. P., Witteles, R. M., Bhalla, V. & Massaro, J. M., 4 Dec 2010, In : The Lancet. 376, 9756, p. 1903-1909 7 p.

Research output: Contribution to journalArticle

1675 Citations (Scopus)