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Author

  • Markus Schlaich

New Approaches in the Management of Sudden Cardiac Death in Patients with Heart FailureTargeting the Sympathetic Nervous System

Kiuchi, M. G., Nolde, J. M., Villacorta, H., Carnagarin, R., Chan, J. J. S-Y., Lugo-Gavidia, L. M., Ho, J. K., Matthews, V. B., Dwivedi, G. & Schlaich, M. P., 2 May 2019, In : International Journal of Molecular Sciences. 20, 10, 27 p., 2430.

Research output: Contribution to journalReview article

Open Access

New drugs, procedures, and devices for hypertension

Laurent, S., Schlaich, M. & Esler, M., 2012, In : The Lancet. 380, 9841, p. 591-600 10 p.

Research output: Contribution to journalArticle

106 Citations (Scopus)

New insights about post-exercise albuminuria in hypertensive patients

Kiuchi, M. G., Chen, S., Carnagarin, R. & Schlaich, M. P., 8 Jul 2019, In : Journal of Clinical Hypertension. 3 p.

Research output: Contribution to journalEditorial

New Molecules for Treating Resistant Hypertension: a Clinical Perspective

Azzam, O., Kiuchi, M. G., Ho, J. K., Matthews, V. B., Gavidia, L. M. L., Nolde, J. M., Carnagarin, R. & Schlaich, M. P., 1 Oct 2019, In : Current Hypertension Reports. 21, 10, 80.

Research output: Contribution to journalReview article

New therapeutic approaches to resistant hypertension

Schlaich, M. P., Krum, H. & Esler, M. D., Aug 2010, In : Current Hypertension Reports. 12, 4, p. 296-302 7 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Novel procedure- and device-based strategies in the management of systemic hypertension

Krum, H., Schlaich, M., Sobotka, P., Scheffers, I., Kroon, A. A. & De Leeuw, P. W., Mar 2011, In : European Heart Journal. 32, 5, p. 537-544 8 p.

Research output: Contribution to journalReview article

Open Access
36 Citations (Scopus)

Obesity-Associated Organ Damage and Sympathetic Nervous Activity: A Target for Treatment?

Lambert, E. A., Esler, M. D., Schlaich, M. P., Dixon, J., Eikelis, N. & Lambert, G. W., Jun 2019, In : Hypertension. 73, 6, p. 1150-1159 10 p.

Research output: Contribution to journalReview article

Obesity Paradox in Hypertension: Is This because Sympathetic Activation in Obesity-Hypertension Takes a Benign Form?

Esler, M., Lambert, G., Schlaich, M., Dixon, J., Sari, C. I. & Lambert, E., 1 Jan 2018, In : Hypertension. 71, 1, p. 22-33 12 p.

Research output: Contribution to journalReview article

22 Citations (Scopus)

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

427 Citations (Scopus)

Percutaneous transluminal renal denervation: A potential treatment option for polycystic kidney disease-related pain?

Shetty, S., Roberts, T. J. & Schlaich, M. P., 2013, In : International Journal of Cardiology. 162, 3, p. e58-e59

Research output: Contribution to journalLetter

18 Citations (Scopus)

Pharmacotherapeutic strategies for treating hypertension in patients with obesity

Carnagarin, R., Matthews, V., Gregory, C. & Schlaich, M. P., 3 May 2018, In : Expert Opinion on Pharmacotherapy. 19, 7, p. 643-651 9 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

Esler, M., Lambert, E. & Schlaich, M., Dec 2010, In : Journal of Applied Physiology. 109, 6, p. 1996-1998 3 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Postchallenge hyperglycemia is closely related with early vascular damage in overweight and obese patients

Schneider, M. P., Ott, C., Ritt, M., Raff, U., Schlaich, M. P. & Schmieder, R. E., 2012, In : Journal of Hypertension. 30, 1, p. 147-152 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rationale and design of a large registry on renal denervation: The Global SYMPLICITY registry

Böhm, M., Mahfoud, F., Ukena, C., Bauer, A., Fleck, E., Hoppe, U. C., Kintscher, U., Narkiewicz, K., Negoita, M., Ruilope, L., Rump, L. C., Schlaich, M., Schmieder, R., Sievert, H., Weil, J., Williams, B., Zeymer, U. & Mancia, G., Aug 2013, In : EuroIntervention. 9, 4, p. 484-492 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Rebuttal from Esler, Lambert, and Schlaich.

Esler, M., Lambert, E. & Schlaich, M., 2010, In : Journal of applied physiology (Bethesda, Md. : 1985). 109, 6, p. 2000-2001 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Rebuttal from Markus P. Schlaich, Yusuke Sata and Murray D. Esler

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Recent advances in the treatment of hypertension

Hering, D., Esler, M. D., Krum, H., Mahfoud, F., Böhm, M., Sobotka, P. A. & Schlaich, M. P., 1 Jun 2011, In : Expert Review of Cardiovascular Therapy. 9, 6, p. 729-744 16 p.

Research output: Contribution to journalReview article

14 Citations (Scopus)

Recurrent postural vasovagal syncope: Sympathetic nervous system phenotypes

Vaddadi, G., Guo, L., Esler, M., Socratous, F., Schlaich, M., Chopra, R., Eikelis, N., Lambert, G., Trauer, T. & Lambert, E., Oct 2011, In : Circulation: Arrhythmia and Electrophysiology. 4, 5, p. 711-718 8 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Reduction in basal nitric oxide activity causes albuminuria

Ott, C., Schneider, M. P., Delles, C., Schlaich, M. P. & Schmieder, R. E., Feb 2011, In : Diabetes. 60, 2, p. 572-576 5 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)

Reduction in blood pressure following renal denervation for patients with differing baseline cardiovascular risk

Mahfoud, F., Mancia, G., Schmieder, R., Narkiewicz, K., Ruilope, L., Schlaich, M., Williams, B., Fahy, M. & Bohm, M., Oct 2019, In : European Heart Journal. 40, p. 663-663 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

10 Citations (Scopus)

Regulation of the sympathetic nervous system by the kidney

Larsen, R., Thorp, A. & Schlaich, M., 2014, In : Current Opinion in Nephrology and Hypertension. 23, 1, p. 61-68 8 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Relation between QT interval variability and cardiac sympathetic activity in hypertension

Baumert, M., Schlaich, M. P., Nalivaiko, E., Lambert, E., Sari, C. I., Kaye, D. M., Elser, M. D., Sanders, P. & Lambert, G., Apr 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 300, 4

Research output: Contribution to journalArticle

71 Citations (Scopus)
Open Access

Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Duval, J., Lee, R., Sata, Y., Krum, H., Lambert, E., Peter, K., Head, G., Lambert, G., Esler, M. D. & Schlaich, M., 1 Jan 2016, In : International Journal of Cardiology. 202, p. 388-393 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Renal artery anatomy assessed by quantitative analysis of selective renal angiography in 1,000 patients with hypertension

Lauder, L., Ewen, S., Tzafriri, A. R., Edelman, E. R., Lüscher, T. F., Blankestijn, P. J., Dörr, O., Schlaich, M., Sharif, F., Voskuil, M., Zeller, T., Ukena, C., Scheller, B., Böhm, M. & Mahfoud, F., 1 May 2018, In : EuroIntervention. 14, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Renal artery radiofrequency ablation for refractory hypertension

Schlaich, M., 2010, In : Cardiology in General Practice. 113, p. 16-18

Research output: Contribution to journalReview article

Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves

Hennebry, S. C., Eikelis, N., Socratous, F., Desir, G., Lambert, G. & Schlaich, M., Mar 2010, In : Molecular Psychiatry. 15, 3, p. 234-236 3 p.

Research output: Contribution to journalLetter

Open Access
62 Citations (Scopus)

Renalase - A potential biomarker for risk of atrial fibrillation?

Schlaich, M. P., Lambert, G. W. & Eikelis, N., 14 Aug 2018, In : Kardiologia Polska. 76, 8, p. 1201-1202 2 p.

Research output: Contribution to journalEditorial

Open Access
2 Citations (Scopus)

Renal denervation: one step backwards, three steps forward

Schlaich, M. P. & Bakris, G. L., Oct 2018, In : Nature Reviews Nephrology. 14, 10, p. 602-604 2 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Renal denervation: A potential new treatment modality for polycystic ovary syndrome?

Schlaich, M. P., Straznicky, N., Grima, M., Ika-Sari, C., Dawood, T., Mahfoud, F., Lambert, E., Chopra, R., Socratous, F., Hennebry, S., Eikelis, N., Böhm, M., Krum, H., Lambert, G., Esler, M. D. & Sobotka, P. A., May 2011, In : Journal of Hypertension. 29, 5, p. 991-996 6 p.

Research output: Contribution to journalArticle

131 Citations (Scopus)

Renal denervation and hypertension

Schlaich, M. P., Krum, H., Sobotka, P. A. & Esler, M. D., Jun 2011, In : American Journal of Hypertension. 24, 6, p. 635-642 8 p.

Research output: Contribution to journalArticle

Open Access
46 Citations (Scopus)

Renal denervation and pulmonary vein isolation in patients with drug resistant hypertension and symptomatic atrial fibrillation

Wilson, S., Kistler, P. M., Mclellan, A. J. A., Hering, D. & Schlaich, M., 2014, In : JOURNAL OF ATRIAL FIBRILLATION. 7, 4, p. 69-74

Research output: Contribution to journalReview article

1 Citation (Scopus)

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

Renal denervation for resistant hypertension—the Symplicity HTN-1 study – Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 1 May 2014, In : The Lancet. 383, 9932, p. 1885-1886

Research output: Contribution to journalLetter

Renal Denervation for Treating Hypertension Current Scientific and Clinical Evidence

Weber, M. A., Mahfoud, F., Schmieder, R. E., Kandzari, D. E., Tsioufis, K. P., Townsend, R. R., Kario, K., Bohm, M., Sharp, A. S. P., Davies, J. E., Osborn, J. W., Fink, G. D., Euler, D. E., Cohen, D. L., Schlaich, M. P. & Esler, M. D., 24 Jun 2019, In : JACC: Cardiovascular Interventions. 12, 12, p. 1095-1105 11 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Renal denervation in human hypertension: Mechanisms, current findings, and future prospects

Schlaich, M. P., Hering, D., Sobotka, P. A., Krum, H. & Esler, M. D., 1 Jun 2012, In : Current Hypertension Reports. 14, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation in moderate to severe CKD

Hering, D., Mahfoud, F., Walton, A. S., Krum, H., Lambert, G. W., Lambert, E. A., Sobotka, P. A., Böhm, M., Cremers, B., Esler, M. D. & Schlaich, M. P., 1 Jul 2012, In : Journal of the American Society of Nephrology. 23, 7, p. 1250-1257 8 p.

Research output: Contribution to journalArticle

Open Access
272 Citations (Scopus)

Renal DenervationReady for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M. P., Kiuchi, M. G. & Esler, M. D., Aug 2018, In : Hypertension. 72, 2, p. 287-290 4 p.

Research output: Contribution to journalEditorial

5 Citations (Scopus)

Renal Denervation - Ready for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M., Galindo Kiuchi, M. & Esler, M. D., Aug 2018, In : Hypertension. 72, p. 287–290

Research output: Contribution to journalEditorial

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal Denervation Update From the International Sympathetic Nervous System Summit

Kiuchi, M. G., Esler, M. D., Fink, G. D., Osborn, J. W., Banek, C. T., Boehm, M., Denton, K. M., DiBona, G. F., Everett, T. H., Grassi, G., Katholi, R. E., Knuepfer, M. M., Kopp, U. C., Lefer, D. J., Lohmeier, T. E., May, C. N., Mahfoud, F., Paton, J. F. R., Schmieder, R. E., Pellegrino, P. R. & 2 others, Sharabi, Y. & Schlaich, M. P., 18 Jun 2019, In : Journal of the American College of Cardiology. 73, 23, p. 3006-3017 12 p.

Research output: Contribution to journalReview article

Open Access
9 Citations (Scopus)

Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Cremers, B., Janker, J., Link, B., Vonend, O., Ukena, C., Linz, D., Schmieder, R., Rump, L. C., Kindermann, I., Sobotka, P. A., Krum, H., Scheller, B., Schlaich, M., Laufs, U. & Böhm, M., 1 Aug 2012, In : Hypertension. 60, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

Open Access
241 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal nerve ablation reduces blood pressure in a patient with renovascular hypertension resistant to drug and revascularisation therapies

Hering, D., Walton, A., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 23 Aug 2012, In : International Journal of Cardiology. 159, 2

Research output: Contribution to journalArticle

9 Citations (Scopus)