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  • Markus Schlaich

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

Renal denervation for resistant hypertension—the Symplicity HTN-1 study – Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 1 May 2014, In : The Lancet. 383, 9932, p. 1885-1886

Research output: Contribution to journalLetter

Renal Denervation for Treating Hypertension Current Scientific and Clinical Evidence

Weber, M. A., Mahfoud, F., Schmieder, R. E., Kandzari, D. E., Tsioufis, K. P., Townsend, R. R., Kario, K., Bohm, M., Sharp, A. S. P., Davies, J. E., Osborn, J. W., Fink, G. D., Euler, D. E., Cohen, D. L., Schlaich, M. P. & Esler, M. D., 24 Jun 2019, In : JACC: Cardiovascular Interventions. 12, 12, p. 1095-1105 11 p.

Research output: Contribution to journalReview article

5 Citations (Scopus)

Renal denervation in human hypertension: Mechanisms, current findings, and future prospects

Schlaich, M. P., Hering, D., Sobotka, P. A., Krum, H. & Esler, M. D., 1 Jun 2012, In : Current Hypertension Reports. 14, 3, p. 247-253 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation in less severe forms of (resistant) hypertension—Quo vadis?

Schlaich, M. P., Hering, D. & Sata, Y., 1 Apr 2017, In : Journal of Clinical Hypertension. 19, 4, p. 369-370 2 p.

Research output: Contribution to journalComment/debate

Renal denervation in moderate to severe CKD

Hering, D., Mahfoud, F., Walton, A. S., Krum, H., Lambert, G. W., Lambert, E. A., Sobotka, P. A., Böhm, M., Cremers, B., Esler, M. D. & Schlaich, M. P., 1 Jul 2012, In : Journal of the American Society of Nephrology. 23, 7, p. 1250-1257 8 p.

Research output: Contribution to journalArticle

Open Access
271 Citations (Scopus)

Renal DenervationReady for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M. P., Kiuchi, M. G. & Esler, M. D., Aug 2018, In : Hypertension. 72, 2, p. 287-290 4 p.

Research output: Contribution to journalEditorial

5 Citations (Scopus)

Renal Denervation - Ready for Prime Time!? The Steep SPYRAL Stairs to RADIANCE in Hypertension Treatment

Schlaich, M., Galindo Kiuchi, M. & Esler, M. D., Aug 2018, In : Hypertension. 72, p. 287–290

Research output: Contribution to journalEditorial

Renal Denervation Reduces Monocyte Activation and Monocyte-Platelet Aggregate Formation: An Anti-Inflammatory Effect Relevant for Cardiovascular Risk

Zaldivia, M. T. K., Rivera, J., Hering, D., Marusic, P., Sata, Y., Lim, B., Eikelis, N., Lee, R., Lambert, G. W., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Eisenhardt, S. U., Flierl, U., Schlaich, M. P. & Peter, K., 1 Feb 2017, In : Hypertension. 69, 2, p. 323-331 9 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
223 Downloads (Pure)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal Denervation Update From the International Sympathetic Nervous System Summit

Kiuchi, M. G., Esler, M. D., Fink, G. D., Osborn, J. W., Banek, C. T., Boehm, M., Denton, K. M., DiBona, G. F., Everett, T. H., Grassi, G., Katholi, R. E., Knuepfer, M. M., Kopp, U. C., Lefer, D. J., Lohmeier, T. E., May, C. N., Mahfoud, F., Paton, J. F. R., Schmieder, R. E., Pellegrino, P. R. & 2 others, Sharabi, Y. & Schlaich, M. P., 18 Jun 2019, In : Journal of the American College of Cardiology. 73, 23, p. 3006-3017 12 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)

Renal hemodynamics and renal function after catheter-based renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Cremers, B., Janker, J., Link, B., Vonend, O., Ukena, C., Linz, D., Schmieder, R., Rump, L. C., Kindermann, I., Sobotka, P. A., Krum, H., Scheller, B., Schlaich, M., Laufs, U. & Böhm, M., 1 Aug 2012, In : Hypertension. 60, 2, p. 419-424 6 p.

Research output: Contribution to journalArticle

Open Access
240 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal nerve ablation reduces blood pressure in a patient with renovascular hypertension resistant to drug and revascularisation therapies

Hering, D., Walton, A., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 23 Aug 2012, In : International Journal of Cardiology. 159, 2

Research output: Contribution to journalArticle

9 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Renal sympathetic denervation: a viable option for treating resistant hypertension

Schlaich, M. P., Sep 2017, In : American Journal of Hypertension. 30, 9, p. 847-856 10 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Renal sympathetic denervation for treatment of drug-resistant hypertension: One-year results from the symplicity htn-2 randomized, controlled trial

Esler, M. D., Krum, H., Schlaich, M., Schmieder, R. E., Böhm, M. & Sobotka, P. A., 18 Dec 2012, In : Circulation. 126, 25, p. 2976-2982 7 p.

Research output: Contribution to journalArticle

Open Access
354 Citations (Scopus)

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

Esler, M. D., Krum, H., Sobotka, P. A., Schlaich, M. P., Schmieder, R. E., Böhm, M., Mahfoud, F., Sievert, H., Wunderlich, N., Rump, L. C., Vonend, O., Uder, M., Lobo, M., Caulfield, M., Erglis, A., Azizi, M., Sapoval, M., Thambar, S., Persu, A., Renkin, J. & 24 others, Schunkert, H., Weil, J., Hoppe, U. C., Walton, T., Scheinert, D., Binder, T., Januszewicz, A., Witkowski, A., Ruilope, L. M., Whitbourn, R., Bruck, H., Downes, M., Lüscher, T. F., Jardine, A. G., Webster, M. W., Zeller, T., Sadowski, J., Bartus, K., Straley, C. A., Barman, N. C., Lee, D. P., Witteles, R. M., Bhalla, V. & Massaro, J. M., 4 Dec 2010, In : The Lancet. 376, 9756, p. 1903-1909 7 p.

Research output: Contribution to journalArticle

1677 Citations (Scopus)

Renal sympathetic denervation restores aortic distensibility in patients with resistant hypertension: data from a multi-center trial

Stoiber, L., Mahfoud, F., Zamani, S. M., Lapinskas, T., Böhm, M., Ewen, S., Kulenthiran, S., Schlaich, M. P., Esler, M. D., Hammer, T., Stensæth, K. H., Pieske, B., Dreysse, S., Fleck, E., Kühne, T., Kelm, M., Stawowy, P. & Kelle, S., 1 Aug 2018, In : Clinical Research in Cardiology. 107, 8, p. 642-652 11 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Renal sympathetic nerve ablation: The new frontier in the treatment of hypertension

Schlaich, M. P., Krum, H. & Sobotka, P. A., 1 Feb 2010, In : Current Hypertension Reports. 12, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

34 Citations (Scopus)

Renal sympathetic nerve ablation for the management of resistant hypertension: An update

Thorp, A. A., Larsen, R. N. & Schlaich, M. P., Nov 2013, In : Current Opinion in Nephrology and Hypertension. 22, 6, p. 607-614 8 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Reply to letter to the Editor entitled: Ambulatory arterial stiffness index: a (too) easy predictor for renal denervation success?

Sata, Y., Head, G. A., Esler, M. D. & Schlaich, M. P., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1606-1607 2 p.

Research output: Contribution to journalLetter

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Resistant Hypertension: Which Agent?

Prosser, H. C. G., Azzam, O. & Schlaich, M. P., 1 Aug 2018, In : Heart Lung and Circulation. 27, 8, p. 911-916 6 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Response to letter regarding article, "ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension"

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 20 May 2014, In : Circulation. 129, 20

Research output: Contribution to journalLetter

Open Access

Response to letter regarding article, "effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study"

Mahfoud, F., Schlaich, M., Kindermann, I., Ukena, C., Cremers, B., Brandt, M. C., Hoppe, U. C., Vonend, O., Rump, L. C., Sobotka, P. A., Krum, H., Esler, M. & Böhm, M., 15 Nov 2011, In : Circulation. 124, 20

Research output: Contribution to journalLetter

Open Access

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access

Response to quality of life after renal denervation

Lambert, G. W., Hering, D., Esler, M. D., Marusic, P., Lambert, E. A., Tanamas, S. K., Shaw, J., Krum, H., Dixon, J. B., Barton, D. A. & Schlaich, M. P., Apr 2013, In : Hypertension. 61, 4

Research output: Contribution to journalLetter

Open Access
2 Citations (Scopus)
2 Citations (Scopus)

Role of the sympathetic nervous system and its modulation in renal hypertension

Sata, Y., Head, G. A., Denton, K., May, C. N. & Schlaich, M. P., 29 Mar 2018, In : Frontiers in Medicine. 5, March, 82.

Research output: Contribution to journalReview article

Open Access
21 Citations (Scopus)

Role of the sympathetic nervous system in regulation of the sodium glucose cotransporter 2

Matthews, V. B., Elliot, R. H., Rudnicka, C., Hricova, J., Herat, L. & Schlaich, M. P., 1 Oct 2017, In : Journal of Hypertension. 35, 10, p. 2059–2068

Research output: Contribution to journalArticle

39 Citations (Scopus)

Rosuvastatin improves pulse wave reflection by restoring endothelial function

Ott, C., Schneider, M. P., Schlaich, M. P. & Schmieder, R. E., Jul 2012, In : Microvascular Research. 84, 1, p. 60-64 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
1 Citation (Scopus)

Serum uric acid and the relationship with subclinical organ damage in adults

Lambert, E. A., Hachem, M., Hemmes, R., Straznicky, N. E., Eikelis, N., Sari, C. I., Schlaich, M. P., Lambert, G. W. & Dixon, J. B., 1 Apr 2017, In : Journal of Hypertension. 35, 4, p. 745-752 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Shaping the future of renal denervation-the relevance of sham-controlled randomized trials and recent meta-analyses

Galindo Kiuchi, M., Ho, J., Lugo Gavidia, L. M. & Schlaich, M., 2019, In : Journal of American College of Cardiology. 73, p. 1633-1642

Research output: Contribution to journalEditorial

22 Citations (Scopus)

Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Single-unit muscle sympathetic nervous activity and its relation to cardiac noradrenaline spillover

Lambert, E. A., Schlaich, M. P., Dawood, T., Sari, C., Chopra, R., Barton, D. A., Kaye, D. M., Elam, M., Esler, M. D. & Lambert, G. W., May 2011, In : Journal of Physiology. 589, 10, p. 2597-2605 9 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

Soluble vascular endothelial growth factor receptor-1 is reduced in patients with resistant hypertension after renal denervation

Eikelis, N., Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Sata, Y., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Apr 2017, In : Journal of Human Hypertension. 31, 4, p. 248-252 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Stress and Neurovascular Coupling: A Red Flag? The SABPA Study

Malan, L., Hamer, M., von Kanel, R., Smith, W., Ziemssen, T., Kotliar, K., Lambert, G., Schlaich, M., Vilser, W., Magnusson, M., Steyn, F. & Malan, N., 2019, In : Journal of Vascular Research. 56, p. 76-76 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Stressing the Metabolic Powers of Fibroblast Growth Factor 21

Magno, A., Herat, L., Carnagarin, R., Schlaich, M. & Matthews, V., 30 Sep 2018, In : AME Medical Journal.

Research output: Contribution to journalEditorial

Open Access

Stress reactivity and its association with increased cardiovascular risk: A role for the sympathetic nervous system?

Lambert, G., Schlaich, M., Lambert, E., Dawood, T. & Esler, M., Jun 2010, In : Hypertension. 55, 6

Research output: Contribution to journalLetter

Open Access
10 Citations (Scopus)

Substantial blood pressure reduction with renal denervation in a drug-naïve patient intolerant to antihypertensive pharmacotherapy: A case report

Xu, J., Walton, A., Hering, D., Sata, Y. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 8, p. 517-518 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
247 Citations (Scopus)

Successful Renal Denervation Decreases the Platelet Activation Status in Hypertensive Patients

Zaldivia, M. T. K., Hering, D., Marusic, P., Sata, Y., Lee, R., Esler, M. D., Htun, N. M., Duval, J., Hammond, L., Flierl, U., Wang, X., Drummond, G. R., Walton, A., Gardiner, E. E., Andrews, R. K., Schlaich, M. P. & Peter, K., Jan 2019, In : Cardiovascular Research. 116, 1, p. 202-210

Research output: Contribution to journalArticle

1 Citation (Scopus)

Suitability for catheter-based renal denervation-lessons from 'super-responders'

Schlaich, M. P., Carnagarin, R., Ho, J. K. & Matthews, V. B., 1 Jul 2018, In : Journal of Hypertension. 36, 7, p. 1475-1476 2 p.

Research output: Contribution to journalComment/debate