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  • John Newnham
2016

Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure

Ophelders, D. R. M. G., Gussenhoven, R., Lammens, M., Küsters, B., Kemp, M., Newnham, J., Payne, M., Kallapur, S., Jobe, A., Zimmermann, L. J., Kramer, B. & Wolfs, T. G. A. M., 2016, In : Journal of Neuroinflammation. 13, 1, p. article number 29

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)

Parental pre-pregnancy BMI is a dominant early-life risk factor influencing BMI of offspring in adulthood

Rath, N. R., Marsh, J. A., Newnham, J. P., Zhu, K., Atkinson, H. C., Mountain, J. A., Oddy, W. H., Hughes, I. P. P., Harris, M., Leong, G. M. M., Cotterill, A. M. M., Sly, P. D. D., Pennell, C. E. & Choong, C. S., 2016, In : Obesity Science & Practice. 2, 1, p. 48-57 10 p.

Research output: Contribution to journalArticle

Open Access
12 Citations (Scopus)

Intra-amniotic Candida albicans infection induces mucosal injury and inflammation in the ovine fetal intestine

Nikiforou, M., Jacobs, E. M. R. M. R., Kemp, M. W., Hornef, M. W. W., Payne, M. S., Saito, M., Newnham, J. P., Janssen, L. E. W. E. W., Jobe, A., Kallapur, S. G., Kramer, B. & Wolfs, T., 2016, In : Scientific Reports. 6, 9 p., 29806.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
Open Access

Characterization and novel analyses of acute stress response patterns in a population-based cohort of young adults: Influence of gender, smoking, and BMI

Herbison, C. E., Henley, D., Marsh, J., Atkinson, H., Newnham, J., Matthews, S. G., Lye, S. J. & Pennell, C., 3 Mar 2016, In : Stress. 19, 2, p. 139-150 12 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2018

Low-dose betamethasone-acetate for fetal lung maturation in preterm sheep

Schmidt, A. F., Kemp, M. W., Rittenschober-Böhm, J., Kannan, P. S., Usuda, H., Saito, M., Furfaro, L., Watanabe, S., Stock, S., Kramer, B. W., Newnham, J. P., Kallapur, S. G. & Jobe, A. H., 1 Jan 2018, In : American Journal of Obstetrics and Gynecology. 218, 1, p. 132.e1-132.e9 9 p.

Research output: Contribution to journalArticle

Open Access
19 Citations (Scopus)
2016

Genome-wide associations for birth weight and correlations with adult disease

Horikoshi, M., Beaumont, R. N., Day, F. R., Warrington, N. M., Kooijman, M. N., Fernandez-Tajes, J., Feenstra, B., Van Zuydam, N. R., Gaulton, K. J., Grarup, N., Bradfield, J. P., Strachan, D. P., Li-Gao, R., Ahluwalia, T. S., Kreiner, E., Rueedi, R., Lyytikaïnen, L. P., Cousminer, D. L., Wu, Y., Thiering, E. & 143 others, Wang, C. A., Have, C. T., Hottenga, J. J., Vilor-Tejedor, N., Joshi, P. K., Boh, E. T. H., Ntalla, I., Pitkänen, N., Mahajan, A., Van Leeuwen, E. M., Joro, R., Lagou, V., Nodzenski, M., Diver, L. A., Zondervan, K. T., Bustamante, M., Marques-Vidal, P., Mercader, J. M., Bennett, A. J., Rahmioglu, N., Nyholt, D. R., Ma, R. C. W., Tam, C. H. T., Tam, W. H., Ganesh, S. K., Van Rooij, F. J. A., Jones, S. E., Loh, P. R., Ruth, K. S., Tuke, M. A., Tyrrell, J., Wood, A. R., Yaghootkar, H., Scholtens, D. M., Paternoster, L., Prokopenko, I., Kovacs, P., Atalay, M., Willems, S. M., Panoutsopoulou, K., Wang, X., Carstensen, L., Geller, F., Schraut, K. E., Murcia, M., Van Beijsterveldt, C. E. M., Willemsen, G., Appel, E. V. R., Fonvig, C. E., Trier, C., Tiesler, C. M. T., Standl, M., Kutalik, Z., Bonàs-Guarch, S., Hougaard, D. M., Sánchez, F., Torrents, D., Waage, J., Hollegaard, M. V., De Haan, H. G., Rosendaal, F. R., Medina-Gomez, C., Ring, S. M., Hemani, G., McMahon, G., Robertson, N. R., Groves, C. J., Langenberg, C., Luan, JA., Scott, R. A., Zhao, J. H., Mentch, F. D., MacKenzie, S. M., Reynolds, R. M., Lowe, W. L., Tönjes, A., Stumvoll, M., Lindi, V., Lakka, T. A., Van Duijn, C. M., Kiess, W., Körner, A., Sørensen, T. I. A., Niinikoski, H., Pahkala, K., Raitakari, O. T., Zeggini, E., Dedoussis, G. V., Teo, Y. Y., Saw, S. M., Melbye, M., Campbell, H., Wilson, J. F., Vrijheid, M., De Geus, E. J. C. N., Boomsma, D. I., Kadarmideen, H. N., Holm, J. C., Hansen, T., Sebert, S., Hattersley, A. T., Beilin, L. J., Newnham, J. P., Pennell, C. E., Heinrich, J., Adair, L. S., Borja, J. B., Mohlke, K. L., Eriksson, J. G., Widén, E., Kähönen, M., Viikari, J. S., Lehtimäki, T., Vollenweider, P., Bønnelykke, K., Bisgaard, H., Mook-Kanamori, D. O., Hofman, A., Rivadeneira, F., Uitterlinden, A. G., Pisinger, C., Pedersen, O., Power, C., Hyppönen, E., Wareham, N. J., Hakonarson, H., Davies, E., Walker, B. R., Jaddoe, V. W. V., Järvelin, M. R., Grant, S. F. A., Vaag, A. A., Lawlor, D. A., Frayling, T. M., Smith, G. D., Morris, A. P., Ong, K. K., Felix, J. F., Timpson, N. J., Perry, J. R. B., Evans, D. M., McCarthy, M. I. & Freathy, R. M., 2016, In : Nature. 538, 7624, p. 248-252 5 p.

Research output: Contribution to journalArticle

161 Citations (Scopus)
2017

The impact of antenatal exposure to environmentally ubiquitous bisphenol A (BPA) on measures of male reproductive function at 20 years of age

Hart, R., Doherty, D., Keelan, J., McLachlan, R., Dickinson, J., Newnham, J., Pennell, C., Norman, R. & Handelsman, D., Jul 2017, In : Human Reproduction. 32, p. 81-82 2 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2 Citations (Scopus)

Pulmonary vascular changes in extremely preterm sheep after intra-amniotic exposure to Ureaplasma parvum and lipopolysaccharide

Willems, M. G. M., Kemp, M. W., Fast, L. A., Wagemaker, N. M. M., Janssen, L. E. W., Newnham, J. P., Payne, M. S., Spiller, O. B., Kallapur, S. G., Jobe, A. H., Delhaas, T., Kramer, B. W. & Wolfs, T. G. A. M., 30 Jun 2017, In : PLoS One. 12, 6, 16 p., 0180114.

Research output: Contribution to journalArticle

Open Access
6 Citations (Scopus)
2016

Maternofetal pharmacokinetics and fetal lung responses in chronically catheterized sheep receiving constant, low-dose infusions of betamethasone phosphate

Kemp, M. W., Saito, M., Usuda, H., Molloy, T. J., Miura, Y., Sato, S., Watanabe, S., Clarke, M., Fossler, M., Scmidt, A., Kallapur, S. G., Kramer, B. W., Newnham, J. P. & Jobe, A. H., 1 Dec 2016, In : American Journal of Obstetrics and Gynecology. 215, 6, p. 775.e1-775.e12

Research output: Contribution to journalArticle

22 Citations (Scopus)
2020

Chronic Intra-Uterine Ureaplasma parvum Infection Induces Injury of the Enteric Nervous System in Ovine Fetuses

Heymans, C., de Lange, I. H., Hütten, M. C., Lenaerts, K., de Ruijter, N. J. E., Kessels, L. C. G. A., Rademakers, G., Melotte, V., Boesmans, W., Saito, M., Usuda, H., Stock, S. J., Spiller, O. B., Payne, M. S., Kramer, B. W., Newnham, J. P., Jobe, A. H., Kemp, M. W., van Gemert, W. G. & Wolfs, T. G. A. M., 17 Mar 2020, In : Frontiers in Immunology. 11, 189.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

Delayed Versus Immediate Cord Clamping in Preterm Infants EDITORIAL COMMENT

Australian Placental Transfusion, May 2018, In : OBSTETRICAL & GYNECOLOGICAL SURVEY. 73, 5, p. 265-266 2 p.

Research output: Contribution to journalEditorial

2017

Delayed versus Immediate Cord Clamping in Preterm Infants

Tarnow-Mordi, W., Morris, J., Kirby, A., Robledo, K., Askie, L., Brown, R., Evans, N., Finlayson, S., Fogarty, M., Gebski, V., Ghadge, A., Hague, W., Isaacs, D., Jeffery, M., Keech, A., Kluckow, M., Popat, H., Sebastian, L., Aagaard, K., Belfort, M. & 36 others, Pammi, M., Abdel-Latif, M., Reynolds, G., Ariff, S., Sheikh, L., Chen, Y., Colditz, P., Liley, H., Pritchard, M., de Luca, D., de Waal, K., Forder, P., Duley, L., El-Naggar, W., Gill, A., Newnham, J., Simmer, K., Groom, K., Weston, P., Gullam, J., Patel, H., Koh, G., Lui, K., Marlow, N., Morris, S., Sehgal, A., Wallace, E., Soll, R., Young, L., Sweet, D., Walker, S., Watkins, A., Wright, I., Osborn, D., Simes, J. & Australian Placental Transfusion, 21 Dec 2017, In : The New England Journal of Medicine. 377, 25, p. 2445-2455 11 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)

Cohort Profile: The Western Australian Pregnancy Cohort (Raine) Study-Generation 2

Straker, L. M., Mountain, J., Jacques, A., White, S., Smith, A. J., Landau, L., Stanley, F., Newnham, J., Pennell, C. & Eastwood, P., Oct 2017, In : International Journal of Epidemiology. 46, 5, p. 1384-1385

Research output: Contribution to journalArticle

58 Citations (Scopus)
2018

The possible impact of antenatal exposure to ubiquitous phthalates upon male reproductive function at 20 years of age

Hart, R. J., Frederiksen, H., Doherty, D. A., Keelan, J. A., Skakkebaek, N., Minaee, N., McLachlan, R., Newnham, J. P., Dickinson, J. E., Pennell, C. E., Norman, R. & Main, K., 4 Jun 2018, In : Frontiers in Endocrinology. 9, p. 1-11 288.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
106 Downloads (Pure)
2017

SLEEP APNOEA AND SYMPTOMS OF DEPRESSION AND ANXIETY DURING PREGNANCY

Redhead, K., Walsh, J., Galbally, M., Griffin, C., Hillman, D., Newnham, J. & Eastwood, P., Oct 2017, In : Journal of Sleep Research. 26, p. 31-31 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

2020

The elements of success in a comprehensive state-wide program to safely reduce the rate of preterm birth

Newnham, J. P., White, S. W., Lee, H-S., Arrese, C. A., Watts, J. C., Pedretti, M. K., Dickinson, J. E. & Doherty, D. A., 2020, In : PLoS One. 15, 6, p. e0234033

Research output: Contribution to journalArticle

Open Access
2018

The efficacy of antenatal steroid therapy is dependent on the duration of low-concentration fetal exposure: evidence from a sheep model of pregnancy

Kemp, M. W., Saito, M., Usuda, H., Watanabe, S., Sato, S., Hanita, T., Kumagai, Y., Molloy, T. J., Clarke, M., Eddershaw, P. J., Musk, G. C., Schmidt, A., Ireland, D., Furfaro, L., Payne, M. S., Newnham, J. P. & Jobe, A. H., 1 Sep 2018, In : American Journal of Obstetrics and Gynecology. 301.e1-16.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2016

Improving customized fetal biometry by longitudinal modelling

White, S. W., Marsh, J., Lye, S. J., Briollais, L., Newnham, J. & Pennell, C., 2016, In : Journal of Maternal-Fetal and Neonatal Medicine. 29, 12, p. 1888-1894

Research output: Contribution to journalArticle

6 Citations (Scopus)
2020

The Australian Preterm Birth Prevention Alliance

Morris, J., Brown, K. & Newnham, J., 1 Jun 2020, In : Australian and New Zealand Journal of Obstetrics and Gynaecology. 60, 3, p. 321-323 3 p.

Research output: Contribution to journalEditorial

2017
1 Citation (Scopus)
2016

Advances in the Prevention and Treatment of Inflammation-Associated Preterm Birth

Keelan, J. A. & Newnham, J. P., 2016, Swtitzerland: Frontiers Media SA. 101 p. (Frontiers in Immunology)

Research output: Book/ReportEdited book/Anthology

4 Citations (Scopus)
2017
Open Access
File
13 Citations (Scopus)
198 Downloads (Pure)
2016

Early life events predict adult testicular function; data derived from the Western Australian (Raine) birth cohort

Hart, R. J., Doherty, D. A., Keelan, J. A., Mclachlan, R., Skakkebaek, N. E., Norman, R. J., Dickinson, J. E., Pennell, C. E., Newnham, J. P., Hickey, M. & Handelsman, D. J., Sep 2016, In : Journal of Clinical Endocrinology and Metabolism. 101, 9, p. 3333-3344

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
250 Downloads (Pure)
2017

Stable Control of Physiological Parameters, But Not Infection, in Preterm Lambs Maintained on Ex Vivo Uterine Environment Therapy

Miura, Y., Usuda, H., Watanabe, S., Woodward, E., Saito, M., Musk, G., Kallapur, S., Sato, S., Kitanishi, R., Matsuda, T., Newnham, J., Stock, S. & Kemp, M., Oct 2017, In : Journal of Artificial Organs. 41, 10, p. 959–968

Research output: Contribution to journalArticle

6 Citations (Scopus)
2020

Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

Merid, S. K., Novoloaca, A., Sharp, G. C., Küpers, L. K., Kho, A. T., Roy, R., Gao, L., Annesi-Maesano, I., Jain, P., Plusquin, M., Kogevinas, M., Allard, C., Vehmeijer, F. O., Kazmi, N., Salas, L. A., Rezwan, F. I., Zhang, H., Sebert, S., Czamara, D., Rifas-Shiman, S. L. & 73 others, Melton, P. E., Lawlor, D. A., Pershagen, G., Breton, C. V., Huen, K., Baiz, N., Gagliardi, L., Nawrot, T. S., Corpeleijn, E., Perron, P., Duijts, L., Nohr, E. A., Bustamante, M., Ewart, S. L., Karmaus, W., Zhao, S., Page, C. M., Herceg, Z., Jarvelin, M-R., Lahti, J., Baccarelli, A. A., Anderson, D., Kachroo, P., Relton, C. L., Bergström, A., Eskenazi, B., Soomro, M. H., Vineis, P., Snieder, H., Bouchard, L., Jaddoe, V. W., Sørensen, T. I. A., Vrijheid, M., Arshad, S. H., Holloway, J. W., Håberg, S. E., Magnus, P., Dwyer, T., Binder, E. B., DeMeo, D. L., Vonk, J. M., Newnham, J., Tantisira, K. G., Kull, I., Wiemels, J. L., Heude, B., Sunyer, J., Nystad, W., Munthe-Kaas, M. C., Räikkönen, K., Oken, E., Huang, R-C., Weiss, S. T., Antó, J. M., Bousquet, J., Kumar, A., Söderhäll, C., Almqvist, C., Cardenas, A., Gruzieva, O., Xu, C-J., Reese, S. E., Kere, J., Brodin, P., Solomon, O., Wielscher, M., Holland, N., Ghantous, A., Hivert, M-F., Felix, J. F., Koppelman, G. H., London, S. J. & Melén, E., 2 Mar 2020, In : Genome Medicine. 12, 1, p. 25

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2017
Open Access
8 Citations (Scopus)

Intrauterine Candida albicans Infection Causes Systemic Fetal Candidiasis with Progressive Cardiac Dysfunction in a Sheep Model of Early Pregnancy

Stock, S. J., Patey, O., Thilaganathan, B., White, S., Furfaro, L. L., Payne, M. S., Spiller, O. B., Noé, A., Watts, R., Carter, S., Ireland, D. J., Jobe, A. H., Newnham, J. P. & Kemp, M. W., Jan 2017, In : Reproductive Sciences. 24, 1, p. 77-84 8 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
331 Downloads (Pure)

Antenatal Dexamethasone vs Betamethasone dosing for lung maturation in fetal sheep

Schmidt, A. F. F., Kemp, M. W., Kannan, P. S. S., Kramer, B., Newnham, J. P., Kallapur, S. G. & Jobe, A., 2017, In : Pediatric Research. 81, 3, 496-503.

Research output: Contribution to journalArticle

14 Citations (Scopus)
2016

Effect of Regular Exercise Commenced in Early Pregnancy on the Incidence of Gestational Diabetes Mellitus in Overweight and Obese Pregnant

Wang, C., Wei, Y., Zhang, X., Zhang, Y., Xu, C., Feng, Y., Shou, C., Guelfi, K. J., Newnham, J. P. & Yang, H., 2016, In : Diabetes Care. 39, 10, p. e163-e164

Research output: Contribution to journalLetter

19 Citations (Scopus)
2017
Open Access
16 Citations (Scopus)
2018

Extremely preterm fetal sheep lung responses to antenatal steroids and inflammation

Visconti, K., Senthamaraikannan, P., Kemp, M. W., Saito, M., Kramer, B. W., Newnham, J. P., Jobe, A. H. & Kallapur, S. G., Mar 2018, In : American Journal of Obstetrics and Gynecology. 218, 3, p. 349.e1-349.e10

Research output: Contribution to journalArticle

5 Citations (Scopus)
2020

Obstructive sleep apnea is associated with depressive symptoms in pregnancy

Redhead, K., Walsh, J., Galbally, M., Newnham, J. P., Watson, S. J. & Eastwood, P., 12 May 2020, In : Sleep. 43, 5

Research output: Contribution to journalArticle

2017

The impact of life stress on adult depression and anxiety is dependent on gender and timing of exposure

Herbison, C. E., Allen, K., Robinson, M., Newnham, J. & Pennell, C., 1 Oct 2017, In : Development and Psychopathology. 29, 4, p. 1443-1454 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2016
Open Access
6 Citations (Scopus)

Selective IL-1α exposure to the fetal gut, lung, and chorioamnion/skin causes intestinal inflammatory and developmental changes in fetal sheep

Nikiforou, M., Kemp, M., Van Gorp, R., Saito, M., Newnham, J., Reynaert, N., Janssen, L., Jobe, A., Kallapur, S., Kramer, B. & Wolfs, T. G. M., 2016, In : Laboratory Investigation. 96, 1, p. 69-80

Research output: Contribution to journalArticle

Open Access
11 Citations (Scopus)
2017

A randomized clinical trial of exercise during pregnancy to prevent gestational diabetes mellitus and improve pregnancy outcome in overweight and obese pregnant women

Wang, C., Wei, Y., Zhang, X., Zhang, Y., Xu, Q., Sun, Y., Su, S., Zhang, L., Liu, C., Feng, Y., Shou, C., Guelfi, K. J., Newnham, J. P. & Yang, H., 1 Apr 2017, In : American Journal of Obstetrics and Gynecology. 216, 4, p. 340-351 12 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

Recent advances in the prevention of preterm birth

Keelan, J. & Newnham, J., 2017, In : F1000Research. 6, 6(F1000 Faculty Rev):1139

Research output: Contribution to journalReview article

Open Access
14 Citations (Scopus)
2020

Use of stored serum in the study of time trends and geographical differences in exposure of pregnant women to phthalates

Henriksen, L. S., Mathiesen, B. K., Assens, M., Krause, M., Skakkebæk, N. E., Juul, A., Andersson, A. M., Hart, R. J., Newnham, J. P., Keelan, J. A., Pennell, C., Main, K. M. & Frederiksen, H., 1 May 2020, In : Environmental Research. 184, 109231.

Research output: Contribution to journalArticle

Successful use of an artificial placenta–based life support system to treat extremely preterm ovine fetuses compromised by intrauterine inflammation

Usuda, H., Watanabe, S., Saito, M., Ikeda, H., Koshinami, S., Sato, S., Musk, G. C., Fee, E., Carter, S., Kumagai, Y., Takahashi, T., Takahashi, Y., Kawamura, S., Hanita, T., Kure, S., Yaegashi, N., Newnham, J. P. & Kemp, M. W., 4 May 2020, In : American Journal of Obstetrics and Gynecology.

Research output: Contribution to journalArticle

2017

The influence of maternal phthalate exposure upon adult male reproductive function

Hart, R., Frederiksen, H., Doherty, D. A., Keelan, J., Skakkebaek, N. E., Minaee, N., Handelsman, D., Newnham, J., Dickinson, J., Pennell, C., Norman, R. J. & Main, G. K., Sep 2017, In : Fertility and Sterility. 108, 3, p. E30-E30 1 p.

Research output: Contribution to journalAbstract/Meeting Abstract

Open Access
30 Citations (Scopus)
2018

Antenatal Corticosteroid Exposure Disrupts Myelination in the Auditory Nerve of Preterm Sheep

Rittenschober-Böhm, J., Rodger, J., Jobe, A. H., Kallapur, S. G., Doherty, D. A., Kramer, B. W., Payne, M. S., Archer, M., Rittenschober, C., Newnham, J. P., Miura, Y., Berger, A., Matthews, S. G., Kemp, M. W. & Mulders, W., 2018, In : Neonatology. 114, 1, p. 62-68 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2016

Cost effectiveness of universal umbilical cord blood gas and lactate analysis in a tertiary level maternity unit

White, C. R. H., Doherty, D. A., Cannon, J. W., Kohan, R., Newnham, J. P. & Pennell, C. E., 2016, In : Journal of Perinatal Medicine. 44, 5, p. 573-584 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The clinical use of corticosteroids in pregnancy

Kemp, M., Newnham, J., Challis, J., Jobe, A. & Stock, S., Mar 2016, In : Human Reproduction. 22, 2, p. 240-259 20 p.

Research output: Contribution to journalArticle

Open Access
58 Citations (Scopus)
Open Access
14 Citations (Scopus)
2018

Efficacy and safety of antenatal steroids

Kemp, M. W., Jobe, A. H., Usuda, H., Nathanielsz, P. W., Li, C., Kuo, A., Huber, H. F., Clarke, G. D., Saito, M., Newnham, J. P. & Stock, S. J., 1 Oct 2018, In : American journal of physiology. Regulatory, integrative and comparative physiology. 315, 4, p. R825-R839

Research output: Contribution to journalArticle

6 Citations (Scopus)
2017

Preclinical evaluation of drugs to block inflammation-driven preterm birth

Ireland, D. J., Nathan, E. A., Li, S., Charles, A. K., Stinson, L. F., Kemp, M. W., Newnham, J. P. & Keelan, J. A., 1 Jan 2017, In : Innate Immunity. 23, 1, p. 20-33 14 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2016
Open Access
20 Citations (Scopus)