Find Research Outputs — the UWA Profiles and Research Repository

2017

Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect

Sly, P. D., Varghese, J., Noor, F., Tang, M. L. K., Laing, I., Oo, S., Prastanti, F., Le Souef, P. & Holt, P. G., 1 Feb 2017, In : Journal of Allergy and Clinical Immunology. 139, 2, p. 703-705 2 p., e4.

Research output: Contribution to journal › Article

3 Citations (Scopus)

2020

Suboptimal asthma care: Lessons from Australia and a way forward

Schultz, A., le Souef, P. & Barwick, M., Jan 2020, In : Respirology. 25, 1, p. 45-46 2 p.

Research output: Contribution to journal › Editorial

Open Access

2017

Viral-bacterial interactions in childhood respiratory tract infections

Annamalay, A. & Le Souëf, P., 2 May 2017, Viral Infections in Children. Springer International Publishing Switzerland, Vol. 1. p. 193-214 22 p.

Research output: Chapter in Book/Conference paper › Chapter

1 Citation (Scopus)

2020

Gene Expression: the Key to Understanding HIV-1 Infection?

Judge, M., Parker, E., Naniche, D. & Le Souëf, P., 20 May 2020, In : Microbiology and molecular biology reviews : MMBR. 84, 2

Research output: Contribution to journal › Review article

1 Citation (Scopus)

2019

Glutathione S-Transferase Genotype Protects against In Utero Tobacco-linked Lung Function Deficits

Owens, L., Laing, I. A., Murdzoska, J., Zhang, G., Turner, S. W. & Le Souef, P. N., 15 Aug 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 4, p. 462-470 9 p.

Research output: Contribution to journal › Article

Open Access

4 Citations (Scopus)

2020

Toll-like receptor signalling has inverted U-shaped response over time with the Western environment

Guo, J., Song, Y., Saiganesh, A., Hales, B. J., Bosco, A., Le Souëf, P. N. & Zhang, G., 1 Oct 2020, In : Allergy: European Journal of Allergy and Clinical Immunology. 75, 10, p. 2665-2667

Research output: Contribution to journal › Letter

2017

EFFECTS OF IN UTERO SMOKE EXPOSURE ON LUNG FUNCTION FROM INFANCY TO ADULTHOOD AND THE CONTRIBUTION OF GLUTATHIONE S-TRANSFERASE POLYMORPHISMS

Owens, L., Laing, I., Zhang, G., Murdzoska, J., Turner, S., Mullane, D., Cox, D. & Le Souef, P., Mar 2017, In : Respirology. 22, p. 46-46 1 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

2019

Pediatric asthma: An unmet need for more effective, focused treatments

Papadopoulos, N. G., Custovic, A., Cabana, M. D., Dell, S. D., Deschildre, A., Hedlin, G., Hossny, E., Le Souef, P., Matricardi, P. M., Nieto, A., Phipatanakul, W., Pitrez, P. M., Pohunek, P., Gavornikova, M., Jaumont, X. & Price, D. B., Feb 2019, In : Pediatric Allergy and Immunology. 30, 1, p. 7-16 10 p.

Research output: Contribution to journal › Review article

Open Access

19 Citations (Scopus)

2017

Characteristics associated with clinical severity and inflammatory phenotype of naturally occurring virus-induced exacerbations of asthma in adults

Bjerregaard, A., Laing, I. A., Poulsen, N., Backer, V., Sverrild, A., Fally, M., Khoo, S. K., Barrett, L., Baltic, S., Thompson, P. J., Chidlow, G., Sikazwe, C., Smith, D. W., Bochkov, Y. A., Le Souëf, P. & Porsbjerg, C., 1 Feb 2017, In : Respiratory Medicine. 123, p. 34-41 8 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

2020

The impact of cytokine levels in young South African children with and without HIV-associated acute lower respiratory infections

Annamalay, A. A., Abbott, S., Khoo, S. K., Hibbert, J., Bizzintino, J., Zhang, G., Laing, I., Currie, A., Le Souëf, P. N. & Green, R. J., 2020, (Accepted/In press) In : Journal of Medical Virology.

Research output: Contribution to journal › Article

2017

Gene-based analysis of regulatory variants identifies 4 putative novel asthma risk genes related to nucleotide synthesis and signaling

Ferreira, M. A. R., Jansen, R., Willemsen, G., Penninx, B. W., Bain, L. M., Vicente, C. T., Revez, J. A., Matheson, M. C., Hui, J., Tung, J. Y., Baltic, S., Le Souëf, P., Montgomery, G. W., Martin, N. G., Robertson, C. F., James, A., Thompson, P. J., Boomsma, D. I., Hopper, J. L., Hinds, D. A. & 3 others, Werder, R. B., Phipps, S. & Australian Asthma Genetics Consortium Collaborators, 1 Apr 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1148-1157 10 p.

Research output: Contribution to journal › Article

Open Access

File

32 Citations (Scopus)

428 Downloads (Pure)

Infant lung function predicts asthma persistence and remission in young adults

Owens, L., Laing, I. A., Zhang, G. & Le Souëf, P. N., 1 Feb 2017, In : Respirology. 22, 2, p. 289-294 6 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Vascular ring: Unmasked

Ishak, A., Souëf, P. L. & Schultz, A., 1 May 2017, In : Journal of Paediatrics and Child Health. 53, 5, p. 503-506 4 p.

Research output: Contribution to journal › Article

2019

Progressive increase of FcεRI expression across several PBMC subsets is associated with atopy and atopic asthma within school-aged children

Leffler, J., Read, J. F., Jones, A. C., Mok, D., Hollams, E. M., Laing, I. A., Le Souef, P. N., Sly, P. D., Kusel, M. M. H., de Klerk, N. H., Bosco, A., Holt, P. G. & Strickland, D. H., Sep 2019, In : Pediatric Allergy and Immunology. 30, 6

Research output: Contribution to journal › Article

7 Citations (Scopus)

2020

Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants

Guo, J., Zhang, X., Saiganesh, A., Peacock, C., Chen, S., Dykes, G. A., Hales, B. J., Le Souëf, P. N. & Zhang, G., 25 Jul 2020, In : Allergy, Asthma and Clinical Immunology. 16, 1, 67.

Research output: Contribution to journal › Article

Open Access

2017

Clinical characteristics of eosinophilic asthma exacerbations

Bjerregaard, A., Laing, I. A., Backer, V., Fally, M., Khoo, S. K., Chidlow, G., Sikazwe, C., Smith, D. W., Le Souëf, P. & Porsbjerg, C., 1 Feb 2017, In : Respirology. 22, 2, p. 295-300 6 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

High fractional exhaled nitric oxide and sputum eosinophils are associated with an increased risk of future virus-induced exacerbations: A prospective cohort study

Bjerregaard, A., Laing, I. A., Backer, V., Sverrild, A., Khoo, S. K., Chidlow, G., Sikazwe, C., Smith, D. W., Le Souëf, P. & Porsbjerg, C., 1 Aug 2017, In : Clinical and Experimental Allergy. 47, 8, p. 1007-1013 7 p.

Research output: Contribution to journal › Article

19 Citations (Scopus)

Dual responses of CD14 methylation to distinct environments: a role in asthma and allergy

Song, Y., Khoo, S-K., Lee, K. H., Mäkelä, M., Haahtela, T., LeSouëf, P. & Zhang, G. B., Dec 2017, In : The European Respiratory Journal. 50, 6, 1701228.

Research output: Contribution to journal › Letter

2 Citations (Scopus)

Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco

Annamalay, A. A., Jroundi, I., Bizzintino, J., Khoo, S. K., Zhang, G., Lehmann, D., Laing, I. A., Gern, J., Goldblatt, J., Mahraoui, C., Benmessaoud, R., Moraleda, C., Bassat, Q. & Le Souëf, P., 1 Apr 2017, In : Journal of Medical Virology. 89, 4, p. 582-588 7 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

2019

Upper airway cell transcriptomics identify a major new immunological phenotype with strong clinical correlates in young children with acute wheezing

Khoo, S. K., Read, J., Franks, K., Zhang, G., Bizzintino, J., Coleman, L., McCrae, C., Öberg, L., Troy, N. M., Prastanti, F., Everard, J., Oo, S., Borland, M. L., Maciewicz, R. A., Le Souëf, P. N., Laing, I. A. & Bosco, A., 1 Jan 2019, In : Journal of Immunology. 202, 6, p. 1845-1858 14 p.

Research output: Contribution to journal › Article

11 Citations (Scopus)

2020

Aberrant cell migration contributes to defective airway epithelial repair in childhood wheeze

Western Australian Epithelial Research Program (WAERP), Australian Respiratory Epithelium Consortium (AusREC), Buckley, A. G., Coleman, L., Ling, K. M., Garratt, L. W., Martinovich, K. M., Shaw, N. C., Karpievitch, Y. V., Le Souëf, P., Laing, I. A., Vijayasekaran, S., Stick, S. M. & Kicic, A., 24 Mar 2020, In : JCI Insight. 5, 7, e133125.

Research output: Contribution to journal › Article

Open Access

2019

Testing the socioeconomic and environmental determinants of better child-health outcomes in Africa: a cross-sectional study among nations

Bradshaw, C. J. A., Otto, S. P., Mehrabi, Z., Annamalay, A. A., Heft-Neal, S., Wagner, Z. & Le Souëf, P. N., 30 Sep 2019, In : BMJ Open. 9, 9, p. e029968

Research output: Contribution to journal › Article

Open Access

2017

Genetic Variants in the IL-4/IL-13 Pathway Influence Measles Vaccine Responses and Vaccine Failure in Children from Mozambique

Clifford, H. D., Hayden, C. M., Khoo, S-K., Naniche, D., Mandomando, I. M., Zhang, G., Richmond, P. & Le Souef, P. N., Sep 2017, In : Viral Immunology. 30, 7, p. 472-478 7 p.

Research output: Contribution to journal › Article

2 Citations (Scopus)

2020

Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank

Mathioudakis, A. G., Custovic, A., Deschildre, A., Ducharme, F. M., Kalayci, O., Murray, C., Garcia, A. N., Phipatanakul, W., Price, D., Sheikh, A., Agache, I., Bacharier, L., Bonini, M., Castro-Rodriguez, J. A., De Carlo, G., Craig, T., Diamant, Z., Feleszko, W., Ierodiakonou, D., Gern, J. E. & 23 others, Grigg, J., Hedlin, G., Hossny, E. M., Jartti, T., Kaplan, A., Lemanske, R. F., Le Souef, P., Makela, M. J., Matricardi, P. M., Miligkos, M., Morais-Almeida, M., Pite, H., Pitrez, P. M. C., Pohunek, P., Roberts, G., Sanchez-Garcia, S., Tsiligianni, I., Turner, S., Winders, T. A., Wong, G., Xepapadaki, P., Zar, H. J. & Papadopoulos, N. G., Jun 2020, In : Journal of Allergy and Clinical Immunology: In Practice. 8, 6, p. 1953-1960.e9

Research output: Contribution to journal › Article

3 Citations (Scopus)

Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden

Papadopoulos, N. G., Custovic, A., Deschildre, A., Mathioudakis, A. G., Phipatanakul, W., Wong, G., Xepapadaki, P., Agache, I., Bacharier, L., Bonini, M., Castro-Rodriguez, J. A., Chen, Z., Craig, T., Ducharme, F. M., El-Sayed, Z. A., Feleszko, W., Fiocchi, A., Garcia-Marcos, L., Gern, J. E., Goh, A. & 49 others, Gómez, R. M., Hamelmann, E. H., Hedlin, G., Hossny, E. M., Jartti, T., Kalayci, O., Kaplan, A., Konradsen, J., Kuna, P., Lau, S., Le Souef, P., Lemanske, R. F., Mäkelä, M. J., Morais-Almeida, M., Murray, C., Nagaraju, K., Namazova-Baranova, L., Garcia, A. N., Yusuf, O. M., Pitrez, P. M. C., Pohunek, P., Pozo Beltrán, C. F., Roberts, G. C., Valiulis, A., Zar, H. J., Taam, R. A., Azuara, H., Brouard, J., Cros, P., De Lira, C., Dubus, J. C., Dunder, T., Efendieva, K., Egron, C., Emeryk, A., Huerta Villalobos, Y. R., Karen, N., Le Roux, P., Levina, J., Medley, M., Najaraju, M., Yeverino, D. R., Ruotsalainen, M., Szefler, S., Schweitzer, C., Benhumea, B. V., Villarreal, R., Weiss, L. & Zawadzka-Krajewska, A., Sep 2020, In : Journal of Allergy and Clinical Immunology: In Practice. 8, 8, p. 2592-2599.e3

Research output: Contribution to journal › Article

Open Access

8 Citations (Scopus)

2019

Western oropharyngeal and gut microbial profiles are associated with allergic conditions in Chinese immigrant children

Guo, J., Lv, Q., Ariff, A., Zhang, X., Peacock, C. S., Song, Y., Wen, X., Saiganesh, A., Melton, P. E., Dykes, G. A., Moses, E. K., LE Souëf, P. N., Lu, F. & Zhang, G., 1 Aug 2019, In : The World Allergy Organization Journal. 12, 8, 100051.

Research output: Contribution to journal › Article

Open Access

3 Citations (Scopus)

2020

Vitamin D receptor polymorphisms are associated with severity of wheezing illnesses and asthma exacerbations in children

Leiter, K., Franks, K., Borland, M. L., Coleman, L., Harris, L., Le Souëf, P. N. & Laing, I. A., Jul 2020, In : Journal of Steroid Biochemistry and Molecular Biology. 201, 105692.

Research output: Contribution to journal › Article

2019

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

Cuthbertson, L., Oo, S. W. C., Cox, M. J., Khoo, S. K., Cox, D. W., Chidlow, G., Franks, K., Prastanti, F., Borland, M. L., Gern, J. E., Smith, D. W., Bizzintino, J. A., Laing, I. A., Le Souëf, P. N., Moffatt, M. F. & Cookson, W. O. C., 1 Jan 2019, In : PLoS One. 14, 10, e0223990.

Research output: Contribution to journal › Article

Open Access

1 Citation (Scopus)

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