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2013
Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease
Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245Research output: Contribution to journal › Article
26 Citations (Scopus) -
Crohn's disease and smoking: Is it ever too late to quit?
Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671Research output: Contribution to journal › Article
29 Citations (Scopus) -
Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era
Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498Research output: Contribution to journal › Article
20 Citations (Scopus) -
Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice
Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12ppResearch output: Contribution to journal › Article
Open Access39 Citations (Scopus) -
2017
A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.Research output: Contribution to conference › Conference presentation/ephemera
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2016
Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection
Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, , 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.Research output: Contribution to journal › Article
Open Access114 Citations (Scopus) -
2017
Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2019
Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome
Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.Research output: Contribution to journal › Review article
1 Citation (Scopus) -
2012
NAFLD, the changing face of IBD
Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2017
Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study
the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.Research output: Contribution to journal › Article
23 Citations (Scopus) -
2019
Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission
Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.Research output: Contribution to journal › Article
Open Access -
2012
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, , 1 Nov 2012, In : Nature. 491, 7422, p. 119-124Research output: Contribution to journal › Article
2625 Citations (Scopus) -
2014
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD
Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165Research output: Contribution to journal › Review article
95 Citations (Scopus) -
2012
Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study
Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293Research output: Contribution to journal › Article
13 Citations (Scopus) -
2016
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, , 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.Research output: Contribution to journal › Article
38 Citations (Scopus) -
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.Research output: Contribution to journal › Article
251 Citations (Scopus) -
2019
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
2013
Vedolizumab as induction and maintenance therapy for Crohn's disease
GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.Research output: Contribution to journal › Article
1032 Citations (Scopus) -
2017
Serologic antibodies in relation to outcome in postoperative Crohn's disease
Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, , 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.Research output: Contribution to journal › Article
9 Citations (Scopus) -
Efficacy of rectal tacrolimus for induction therapy in patients with resistant ulcerative proctitis
Lawrance, I. C., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 1 Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1248-1255 8 p.Research output: Contribution to journal › Article
25 Citations (Scopus) -
2019
Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
2014
The role of vitamin D in gastrointestinal inflammation
Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923Research output: Contribution to journal › Review article
24 Citations (Scopus) -
What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?
Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
The importance of validating proposed genetic profiles in IBD
Lawrance, I., May 2014, In : Journal of Internal Medicine.Research output: Contribution to journal › Review article
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Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response
Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
2020
The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases
Grosse, C. S. J., Christophersen, C. T., Devine, A. & Lawrance, I. C., 3 Mar 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 3, p. 137-145 9 p.Research output: Contribution to journal › Review article
2 Citations (Scopus) -
2018
Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-Smith, G., Andrews, J. M. & 2 others, , 29 Nov 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.Research output: Contribution to journal › Article
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2016
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access32 Citations (Scopus) -
2019
Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series
Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120Research output: Contribution to journal › Abstract/Meeting Abstract
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2020
Anti-TNF Therapy in Pregnant Women with Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes
Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 others, , Jan 2020, In : Inflammatory Bowel Diseases. 26, 1, p. 93-102 10 p.Research output: Contribution to journal › Article
5 Citations (Scopus) -
2016
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2016
Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study
Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2012
Microbiota and management of inflammatory bowel disease
Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140Research output: Contribution to journal › Review article
3 Citations (Scopus) -
2013
A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents
Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935Research output: Contribution to journal › Article
11 Citations (Scopus) -
2016
A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.Research output: Contribution to journal › Article
Open Access6 Citations (Scopus) -
2017
Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method
Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
Dysplasia and colorectal cancer surveillance in inflammatory bowel disease
Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.Research output: Contribution to journal › Review article
9 Citations (Scopus) -
2016
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile322 Citations (Scopus)419 Downloads (Pure) -
2017
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, , 13 Jul 2017, In : Nature. 547, 7662, p. 173-178 6 p.Research output: Contribution to journal › Article
Open AccessFile172 Citations (Scopus)391 Downloads (Pure) -
2013
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, , 2013, In : PLoS Genetics. 9, 9, p. 11 pp.Research output: Contribution to journal › Article
Open Access112 Citations (Scopus) -
2019
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients
Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.Research output: Contribution to journal › Article
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Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2012
Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease
Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984Research output: Contribution to journal › Review article
5 Citations (Scopus) -
2014
HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, , 2014, In : Nature Genetics. 46, 10, p. 1131-1136Research output: Contribution to journal › Article
104 Citations (Scopus) -
2016
Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection
Julsgaard, M., Christensen, L. A., Gibson, P. R., Gearry, R. B., Fallingborg, J., Hvas, C. L., Bibby, B. M., Uldbjerg, N., Connell, W. R., Rosella, O., Grosen, A., Brown, S. J., Kjeldsen, J., Wildt, S., Svenningsen, L., Sparrow, M. P., Walsh, A., Connor, S. J., Radford-Smith, G., Lawrance, I. & 3 others, , 2016, In : Gastroenterology. 151, 1, p. 110-119Research output: Contribution to journal › Article
129 Citations (Scopus) -
2014
Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function
Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616Research output: Contribution to journal › Article
5 Citations (Scopus)