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2013
Prevention of cancer in IBD - A balancing act
Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272Research output: Contribution to journal › Review article
7 Citations (Scopus) -
2011
Topical agents for idiopathic distal colitis and proctitis
Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43Research output: Contribution to journal › Article
19 Citations (Scopus) -
2013
Prevention of cancer in IBD – a balancing act
Lawrance, I., Sep 2013, In : Minerva Gastroenterologica e Dietologica.Research output: Contribution to journal › Review article
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2014
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927Research output: Contribution to journal › Letter
7 Citations (Scopus) -
2019
Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2014
Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response
Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
2017
Dysplasia and colorectal cancer surveillance in inflammatory bowel disease
Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.Research output: Contribution to journal › Review article
9 Citations (Scopus) -
2014
The importance of validating proposed genetic profiles in IBD
Lawrance, I., May 2014, In : Journal of Internal Medicine.Research output: Contribution to journal › Review article
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2016
Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study
Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.Research output: Contribution to journal › Article
Open Access11 Citations (Scopus) -
2014
Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD
Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165Research output: Contribution to journal › Review article
97 Citations (Scopus) -
HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, , 2014, In : Nature Genetics. 46, 10, p. 1131-1136Research output: Contribution to journal › Article
109 Citations (Scopus) -
2011
Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents
Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418Research output: Contribution to journal › Article
56 Citations (Scopus) -
2013
Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease
International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I. C., 6 Jun 2013, In : American Journal of Human Genetics. 92, 6, p. 1008-1012 5 p.Research output: Contribution to journal › Article
Open Access89 Citations (Scopus) -
2016
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile336 Citations (Scopus)450 Downloads (Pure) -
2011
Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, , 2011, In : PLoS Genetics. 7, 1, p. 13ppResearch output: Contribution to journal › Article
Open Access351 Citations (Scopus) -
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, , 2011, In : Nature Genetics. 43, 3, p. 246-252Research output: Contribution to journal › Article
935 Citations (Scopus) -
2013
A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents
Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935Research output: Contribution to journal › Article
12 Citations (Scopus) -
2019
Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
2017
Serologic antibodies in relation to outcome in postoperative Crohn's disease
Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, , 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.Research output: Contribution to journal › Article
11 Citations (Scopus) -
2019
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients
Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.Research output: Contribution to journal › Article
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2016
Acute severe ulcerative colitis: Changing treatment paradigms
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16Research output: Contribution to journal › Article
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2011
Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program
Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465Research output: Contribution to journal › Review article
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2019
Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series
Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120Research output: Contribution to journal › Abstract/Meeting Abstract
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2017
Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2011
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2013
Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease
Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245Research output: Contribution to journal › Article
27 Citations (Scopus) -
2011
Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD
Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371Research output: Contribution to journal › Article
8 Citations (Scopus) -
2016
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
2011
Predictors of fibrostenotic Crohn's Disease
Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007Research output: Contribution to journal › Article
49 Citations (Scopus) -
2014
What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?
Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2016
A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.Research output: Contribution to journal › Article
Open Access7 Citations (Scopus) -
2014
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
2013
Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice
Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12ppResearch output: Contribution to journal › Article
Open Access42 Citations (Scopus) -
2016
Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection
Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, , 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.Research output: Contribution to journal › Article
Open Access118 Citations (Scopus) -
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access35 Citations (Scopus) -
2013
Crohn's disease and smoking: Is it ever too late to quit?
Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671Research output: Contribution to journal › Article
30 Citations (Scopus) -
2011
SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer
Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13ppResearch output: Contribution to journal › Article
Open Access47 Citations (Scopus) -
2017
Cellular and Molecular Mediators of Intestinal Fibrosis
Lawrance, I., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J., Pellino, G., Reif, S., Speca, S. & Latella, G., Dec 2017, In : Journal of Crohn's and Colitis. 11, 12, p. 1491–1503 13 p.Research output: Contribution to journal › Article
Open Access53 Citations (Scopus) -
2019
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article
Open Access16 Citations (Scopus) -
2016
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.Research output: Contribution to journal › Article
275 Citations (Scopus) -
2014
Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study
Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606Research output: Contribution to journal › Article
68 Citations (Scopus) -
2013
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, , 2013, In : PLoS Genetics. 9, 9, p. 11 pp.Research output: Contribution to journal › Article
Open Access116 Citations (Scopus) -
2017
Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method
Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.Research output: Contribution to journal › Article
Open Access10 Citations (Scopus) -
2013
Vedolizumab as induction and maintenance therapy for Crohn's disease
GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.Research output: Contribution to journal › Article
1071 Citations (Scopus) -
2017
A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.Research output: Contribution to conference › Conference presentation/ephemera
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2011
Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study
Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193Research output: Contribution to journal › Article
99 Citations (Scopus) -
2017
Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2014
Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function
Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616Research output: Contribution to journal › Article
5 Citations (Scopus) -
2019
Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome
Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.Research output: Contribution to journal › Review article
1 Citation (Scopus)