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2014
Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study
Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606Research output: Contribution to journal › Article
64 Citations (Scopus) -
2017
Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2019
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients
Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.Research output: Contribution to journal › Article
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2014
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
2013
Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease
Walsh, A. J., Weltman, M., Burger, D., Vivekanandarajah, S., Connor, S., Howlett, M., Radford-Smith, G., Selby, W., Veillard, A. S., Grimm, M. C., Travis, S. P. L. & Lawrance, I., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, p. e449-e456Research output: Contribution to journal › Article
31 Citations (Scopus) -
2011
Predictors of fibrostenotic Crohn's Disease
Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007Research output: Contribution to journal › Article
48 Citations (Scopus) -
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2016
Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study
Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.Research output: Contribution to journal › Article
Open Access10 Citations (Scopus) -
2011
Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD
Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371Research output: Contribution to journal › Article
8 Citations (Scopus) -
2014
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927Research output: Contribution to journal › Letter
7 Citations (Scopus) -
2013
Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease
International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I. C., 6 Jun 2013, In : American Journal of Human Genetics. 92, 6, p. 1008-1012 5 p.Research output: Contribution to journal › Article
Open Access88 Citations (Scopus) -
2018
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-Smith, G., Andrews, J. M. & 2 others, , 29 Nov 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.Research output: Contribution to journal › Article
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2013
Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis
Ng, Y. L., Klopcic, B., Lloyd, F., Forrest, C., Greene, W. & Lawrance, I., 2013, In : PLoS One. 8, 10, p. 8ppResearch output: Contribution to journal › Article
Open Access16 Citations (Scopus) -
2016
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access33 Citations (Scopus) -
2014
The role of vitamin D in gastrointestinal inflammation
Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923Research output: Contribution to journal › Review article
26 Citations (Scopus) -
2011
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, , 2011, In : Nature Genetics. 43, 3, p. 246-252Research output: Contribution to journal › Article
932 Citations (Scopus) -
2018
Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice
Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.Research output: Contribution to journal › Article
Open Access14 Citations (Scopus) -
2013
Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease
Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245Research output: Contribution to journal › Article
27 Citations (Scopus) -
2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2016
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.Research output: Contribution to journal › Article
260 Citations (Scopus) -
2017
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, , 13 Jul 2017, In : Nature. 547, 7662, p. 173-178 6 p.Research output: Contribution to journal › Article
Open AccessFile178 Citations (Scopus)405 Downloads (Pure) -
2018
Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease
Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, , 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.Research output: Contribution to journal › Article
5 Citations (Scopus) -
2011
Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, , 2011, In : PLoS Genetics. 7, 1, p. 13ppResearch output: Contribution to journal › Article
Open Access349 Citations (Scopus) -
2017
Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method
Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2013
A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents
Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935Research output: Contribution to journal › Article
11 Citations (Scopus) -
Prevention of cancer in IBD - A balancing act
Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272Research output: Contribution to journal › Review article
7 Citations (Scopus) -
2016
Acute severe ulcerative colitis: Changing treatment paradigms
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16Research output: Contribution to journal › Article
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2017
Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study
the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.Research output: Contribution to journal › Article
23 Citations (Scopus) -
Serologic antibodies in relation to outcome in postoperative Crohn's disease
Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, , 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.Research output: Contribution to journal › Article
9 Citations (Scopus) -
2018
Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
2017
Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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Efficacy of rectal tacrolimus for induction therapy in patients with resistant ulcerative proctitis
Lawrance, I. C., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 1 Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1248-1255 8 p.Research output: Contribution to journal › Article
25 Citations (Scopus) -
2019
Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series
Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120Research output: Contribution to journal › Abstract/Meeting Abstract
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Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2017
Cellular and Molecular Mediators of Intestinal Fibrosis
Lawrance, I., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J., Pellino, G., Reif, S., Speca, S. & Latella, G., Dec 2017, In : Journal of Crohn's and Colitis. 11, 12, p. 1491–1503 13 p.Research output: Contribution to journal › Article
Open Access50 Citations (Scopus) -
OP007 A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 26 Jan 2017, In : JOURNAL OF CROHNS & COLITIS. 11, 1Research output: Contribution to journal › Abstract/Meeting Abstract
Open Access -
2016
A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.Research output: Contribution to journal › Article
Open Access6 Citations (Scopus) -
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease
Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C., Oct 2016, In : Inflammatory Bowel Diseases. 22, 10, p. 2456-2464 9 p.Research output: Contribution to journal › Article
12 Citations (Scopus) -
2011
SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer
Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13ppResearch output: Contribution to journal › Article
Open Access45 Citations (Scopus) -
Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study
Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193Research output: Contribution to journal › Article
99 Citations (Scopus) -
2018
Vedolizumab (VDZ) real-world outcomes in ulcerative colitis (UC)
Pulusu, S. S. R., Srinivasan, A., Krishnaprasad, K., Cheng, D., Mogilevski, T., Flanagan, E., Keung, C., Wu, C., Prosser, R., Sawyer, E., Rizvi, Q. U. A., Su, H., Leung, W., Edmundson, A., Cooke, S., Mahy, G., Thin, L., Radford-Smith, G., Sparrow, M. P., Andrews, J. M. & 10 others, , 1 Feb 2018, In : Journal of Crohn's and Colitis. 12, 1, P571.Research output: Contribution to journal › Abstract/Meeting Abstract
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2011
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.Research output: Contribution to journal › Article
505 Citations (Scopus) -
2019
Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome
Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.Research output: Contribution to journal › Review article
1 Citation (Scopus) -
2016
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, , 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.Research output: Contribution to journal › Article
40 Citations (Scopus) -
2013
Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice
Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12ppResearch output: Contribution to journal › Article
Open Access40 Citations (Scopus) -
2016
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile330 Citations (Scopus)431 Downloads (Pure) -
2019
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
2011
Topical agents for idiopathic distal colitis and proctitis
Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43Research output: Contribution to journal › Article
19 Citations (Scopus) -
Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program
Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465Research output: Contribution to journal › Review article