Find Research Outputs — the UWA Profiles and Research Repository

2014

A case of iatrogenic cushing syndrome and apparent mineralocorticoid excess presenting with accelerated hypertension and proteinuria

Kong, W. Y., Leedman, P. & Irish, A., 2014, In : Internal Medicine Journal. 44, 9, p. 932-934

Research output: Contribution to journal › Letter

2013

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

Redfern, A., Colley, S., Beveridge, D., Ikeda, N., Epis, M., Li, X., Foulds, C. E., Stuart, L., Barker, A., Russell, V., Ramsay, K., Kobelke, S., Hatchell, E., Payne, C. J., Giles, K., Messineo, A., Gatignol, A., Lanz, R. B., O'Malley, B. W. & Leedman, P., 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 16, p. 6536-6541

Research output: Contribution to journal › Article

66 Citations (Scopus)

2016

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

2013

Distinct nuclear receptor expression in stroma adjacent to breast tumors

Knower, K. C., Chand, A. L., Eriksson, N., Takagi, K., Miki, Y., Sasano, H., Visvader, J. E., Lindeman, G. J., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Graham, J. D., Muscat, G. E. O., Clarke, C. L. & Clyne, C. D., Nov 2013, In : Breast Cancer Research and Treatment. 142, 1, p. 211-223 13 p.

Research output: Contribution to journal › Article

28 Citations (Scopus)

Research resource: Nuclear receptors as transcriptome: Discriminant and prognostic value in breast cancer

Muscat, G. E. O., Eriksson, N. A., Byth, K., Loi, S., Graham, D., Jindal, S., Davis, M. J., Clyne, C., Funder, J. W., Simpson, E. R., Ragan, M. A., Kuczek, E., Fuller, P. J., Tilley, W. D., Leedman, P. & Clarke, C. L., 2013, In : Molecular Endocrinology. 27, p. 350-365

Research output: Contribution to journal › Article

Open Access

File

56 Citations (Scopus)

554 Downloads (Pure)

2011

The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

Epis, M., Barker, A. P., Giles, K., Beveridge, D. & Leedman, P., 2011, In : The Journal of Biological Chemistry. 286, 48, p. 41442-41454

Research output: Contribution to journal › Article

66 Citations (Scopus)

2013

Axl mediates acquired resistance of head and neck cancer cells to the epidermal growth factor receptor inhibitor erlotinib

Giles, K., Kalinowski, F., Candy, P., Epis, M., Zhang, P., Redfern, A., Stuart, L., Goodal, G. J. & Leedman, P., Nov 2013, In : Molecular Cancer Therapeutics. 12, 11, p. 2541-2558

Research output: Contribution to journal › Article

Open Access

File

95 Citations (Scopus)

600 Downloads (Pure)

2016

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

Brown, S. J., Bremner, A., Hadlow, N. C., Feddema, P., Leedman, P., O'Leary, P. & Walsh, J., Nov 2016, In : Clinical Endocrinology. 85, 5, p. 789-796

Research output: Contribution to journal › Article

Open Access

22 Citations (Scopus)

2013

Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility

Colley, S., Wintle, L., Searles, R., Russell, V., Firman, R., Smith, S., Deboer, K., Merriner, D. J., Genevieve, B., Bentel, J., Stuckey, B., Phillips, M. R., Simmons, L., De Kretser, D. M., O'Bryan, M. K. & Leedman, P., 2013, In : PLoS One. 8, 8, p. 8pp

Research output: Contribution to journal › Article

Open Access

14 Citations (Scopus)

2017

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

Epis, M. R., Giles, K. M., Beveridge, D. J., Richardson, K. L., Candy, P. A., Stuart, L. M., Bentel, J., Cohen, R. J. & Leedman, P. J., 2017, In : Oncotarget. 8, 33, p. 55116-55134 19 p.

Research output: Contribution to journal › Article

Open Access

14 Citations (Scopus)

2015

Clinical potential of microRNA-7 in cancer.

Horsham, J., Kalinowski, F., Epis, M., Ganda, C., Brown, R. & Leedman, P., 2015, In : Journal of Clinical Medicine. 4, 9, p. 1668-1687

Research output: Contribution to journal › Article

Open Access

2014

Breast cancer prognosis predicted by nuclear receptor-coregulator networks

Doan, T. B., Eriksson, N. A., Graham, D., Funder, J. W., Simpson, E. R., Kuczek, E. S., Clyne, C., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., Jul 2014, In : Molecular Oncology. 8, 5, p. 998-1013

Research output: Contribution to journal › Article

Open Access

14 Citations (Scopus)

2011

MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells

Giles, K., Barker, A. P., Zhang, P., Epis, M. & Leedman, P., 2011, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 1st Edition ed. United States: Humana Press, p. 147-163

Research output: Chapter in Book/Conference paper › Other chapter contribution

30 Citations (Scopus)

2014

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Hilton, H. N., Graham, J. D., Oakes, S. R., Silvestri, A., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, p. 8651-8664

Research output: Contribution to journal › Article

20 Citations (Scopus)

PRMT2 and RORy Expression Are Associated With Breast Cancer Survival Outcomes

Oh, T. G., Bailey, P., Dray, E., Smith, A. G., Goode, J., Eriksson, N., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Clarke, C. L., Grimmond, S., Dowhan, D. H. & Muscat, G. E. O., 2014, In : Molecular Endocrinology. 28, p. 1166-1185

Research output: Contribution to journal › Article

27 Citations (Scopus)

2011

miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion

Thomson, D., Giles, K., Maleki, S., Mreich, E., Wheeler, H., Leedman, P., Biggs, M., Cook, R., Little, N., Robinson, B., Mcdonald, K. & Fowler, A., 2011, In : European Journal of Cancer. 47, 6, p. 953-963

Research output: Contribution to journal › Article

99 Citations (Scopus)

2013

Notch-induced transcription factors are predictive of survival and 5-fluorouracil response in colorectal cancer patients

Candy, P. A., Phillips, M., Redfern, A., Colley, S., Davidson, A., Stuart, L., Wood, B. A., Zeps, N. & Leedman, P., 2013, In : British Journal of Cancer. 109, 4, p. 1023-1030

Research output: Contribution to journal › Article

Open Access

40 Citations (Scopus)

2011

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A., Beilby, J., Leedman, P., Hattersley, A. T., Vaidya, B., Frayling, T., Evans, J., Timpson, N. J., Tobias, J. H., Walsh, J. & Dayan, C. M., 2011, In : European Journal of Endocrinology. 164, p. 773-780

Research output: Contribution to journal › Article

26 Citations (Scopus)

2016

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-?B

Giles, K., Brown, R. A., Ganda, C., Podgorny, M., Candy, P., Wintle, L. C., Richardson, K. L., Kalinowski, F. C., Stuart, L. M., Epis, M. R., Haass, N. K., Herlyn, M. & Leedman, P. J., 2016, In : Oncotarget. 7, 22, p. 31663-31680 18 p.

Research output: Contribution to journal › Article

Open Access

46 Citations (Scopus)

2018

Total RNA extraction from tissues for microRNA and target gene expression analysis: Not all kits are created equal

Brown, R. A. M., Epis, M. R., Horsham, J. L., Kabir, T. D., Richardson, K. L. & Leedman, P. J., 16 Mar 2018, In : BMC Biotechnology. 18, 1, 16.

Research output: Contribution to journal › Article

Open Access

28 Citations (Scopus)

Evaluation of microRNA delivery in vivo

Brown, R. A. M., Richardson, K. L., Kalinowski, F. C., Epis, M. R., Horsham, J. L., Kabir, T. D., De Pinho, M. H., Beveridge, D. J., Stuart, L. M., Wintle, L. C. & Leedman, P. J., 2018, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 2nd ed. Humana Press, Vol. 1699. p. 155-178 24 p. (Methods in Molecular Biology; vol. 1699).

Research output: Chapter in Book/Conference paper › Chapter

8 Citations (Scopus)

2020

Direct in vivo comparison of [¹⁸F]PSMA-1007 with [⁶⁸Ga]Ga-PSMA-11 and [¹⁸F]AlF-PSMA-11 in mice bearing PSMA-expressing xenografts

Ioppolo, J. A., Nezich, R. A., Richardson, K. L., Morandeau, L., Leedman, P. J. & Price, R. I., Jul 2020, In : Applied Radiation and Isotopes. 161, 109164.

Research output: Contribution to journal › Article

2 Citations (Scopus)

2015

MicroRNA-7: A miRNA with expanding roles in development and disease

Horsham, J., Ganda, C., Kalinowski, F., Brown, R., Epis, M. & Leedman, P., 2015, In : International Journal of Biochemistry and Cell Biology. 69, p. 215-224

Research output: Contribution to journal › Review article

48 Citations (Scopus)

2018

A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma

Kabir, T. D., Ganda, C., Brown, R. M., Beveridge, D. J., Richardson, K. L., Chaturvedi, V., Candy, P., Epis, M., Wintle, L., Kalinowski, F., Kopp, C., Stuart, L. M., Yeoh, G. C., George, J. & Leedman, P. J., 1 Jan 2018, In : Hepatology. 67, 1, p. 216-231 16 p.

Research output: Contribution to journal › Article

57 Citations (Scopus)

2014

microRNA-7: a tumor suppressor miRNA with therapeutic potential

Kalinowski, F., Brown, R., Ganda, C., Giles, K. M., Epis, M., Horsham, J. & Leedman, P., Sep 2014, In : International Journal of Biochemistry and Cell Biology. 54, p. 312-317

Research output: Contribution to journal › Article

79 Citations (Scopus)

miR-331-3p regulates expression of neuropilin-2 in glioblastoma

Epis, M., Giles, K., Candy, P., Webster, R. & Leedman, P., Jan 2014, In : Journal of Neuro-Oncology. 116, 1, p. 67-75

Research output: Contribution to journal › Article

Open Access

51 Citations (Scopus)

2018

Loss of SLIRP is associated with poorer prognosis and increased invasion in colorectal cancer

Candy, P. A., Colley, S. M., Phillips, M. R., Redfern, A. D., Wood, B. A. & Leedman, P. J., Jun 2018, In : Clinical Endocrinology. 89, p. 41-41 1 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

2014

Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M. & 98 others, Plia, M. G., Sala, C., Voelker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jorgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Raeikkoenen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., Den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Voelzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., Feb 2014, In : PLoS Genetics. 10, 2, p. 1-13 13 p., e1004123.

Research output: Contribution to journal › Article

Open Access

98 Citations (Scopus)

2018

Initial evaluation of thyroid dysfunction - Are simultaneous TSH and fT4 tests necessary?

Schneider, C., Feller, M., Bauer, D. C., Collet, T. H., daCosta, B. R., Auer, R., Peeters, R. P., Brown, S. J., Bremner, A. P., O’Leary, P. C., Feddema, P., Leedman, P. J., Aujesky, D., Walsh, J. P. & Rodondi, N., 1 Apr 2018, In : PLoS One. 13, 4, e0196631.

Research output: Contribution to journal › Article

Open Access

11 Citations (Scopus)

2020

Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology

Brown, R. A. M., Richardson, K. L., Kabir, T. D., Trinder, D., Ganss, R. & Leedman, P. J., 9 Apr 2020, In : Frontiers in Oncology. 10, 476.

Research output: Contribution to journal › Review article

Open Access

6 Citations (Scopus)

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