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2011
Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program
Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465Research output: Contribution to journal › Review article
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2016
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
2012
Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study
Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293Research output: Contribution to journal › Article
13 Citations (Scopus) -
2014
What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?
Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2017
Dysplasia and colorectal cancer surveillance in inflammatory bowel disease
Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.Research output: Contribution to journal › Review article
9 Citations (Scopus) -
2014
Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD
Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165Research output: Contribution to journal › Review article
95 Citations (Scopus) -
2011
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2014
Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study
Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606Research output: Contribution to journal › Article
64 Citations (Scopus) -
2016
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, , 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.Research output: Contribution to journal › Article
38 Citations (Scopus) -
2014
HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, , 2014, In : Nature Genetics. 46, 10, p. 1131-1136Research output: Contribution to journal › Article
104 Citations (Scopus) -
2011
Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents
Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418Research output: Contribution to journal › Article
56 Citations (Scopus) -
2017
A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.Research output: Contribution to conference › Conference presentation/ephemera
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2019
Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission
Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.Research output: Contribution to journal › Article
Open Access -
2020
Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford
Pulusu, S. S. R., Srinivasan, A., Krishnaprasad, K., Cheng, D., Begun, J., Keung, C., van Langenberg, D., Thin, L., Mogilevski, T., De Cruz, P., Radford-Smith, G., Flanagan, E., Bell, S., Kashkooli, S., Sparrow, M. P., Ghaly, S., Bampton, P. A., Sawyer, E., Connor, S., Rizvi, Q-U-A. & 4 others, , 14 Aug 2020, In : World Journal of Gastroenterology. 26, 30, p. 4428-4441Research output: Contribution to journal › Article
Open Access -
2018
Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis
Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.Research output: Contribution to journal › Article
Open Access18 Citations (Scopus) -
2017
Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study
the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.Research output: Contribution to journal › Article
23 Citations (Scopus) -
2019
Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2011
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.Research output: Contribution to journal › Article
502 Citations (Scopus) -
2016
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.Research output: Contribution to journal › Article
248 Citations (Scopus) -
2012
NAFLD, the changing face of IBD
Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2017
Fine-mapping inflammatory bowel disease loci to single-variant resolution
Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, , 13 Jul 2017, In : Nature. 547, 7662, p. 173-178 6 p.Research output: Contribution to journal › Article
Open AccessFile172 Citations (Scopus)386 Downloads (Pure) -
2019
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
2014
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927Research output: Contribution to journal › Letter
7 Citations (Scopus) -
Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response
Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function
Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616Research output: Contribution to journal › Article
5 Citations (Scopus) -
2012
Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease
Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984Research output: Contribution to journal › Review article
5 Citations (Scopus) -
2020
Orally administered emu oil attenuates disease in a mouse model of Crohn’s-like colitis
Mitchell, C. J., Howarth, G. S., Chartier, L. C., Trinder, D., Lawrance, I. C., Huang, L. S. & Mashtoub, S., 2020, (Accepted/In press) In : Experimental Biology and Medicine.Research output: Contribution to journal › Article
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2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2017
OP007 A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 26 Jan 2017, In : JOURNAL OF CROHNS & COLITIS. 11, 1Research output: Contribution to journal › Abstract/Meeting Abstract
Open Access -
2011
Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study
Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193Research output: Contribution to journal › Article
99 Citations (Scopus) -
2018
Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease
Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, , 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.Research output: Contribution to journal › Article
4 Citations (Scopus) -
2017
Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2018
Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice
Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
2020
The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases
Grosse, C. S. J., Christophersen, C. T., Devine, A. & Lawrance, I. C., 3 Mar 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 3, p. 137-145 9 p.Research output: Contribution to journal › Review article
2 Citations (Scopus) -
2012
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, , 1 Nov 2012, In : Nature. 491, 7422, p. 119-124Research output: Contribution to journal › Article
2620 Citations (Scopus) -
2017
Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method
Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2016
Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection
Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, , 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.Research output: Contribution to journal › Article
Open Access111 Citations (Scopus) -
2019
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients
Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.Research output: Contribution to journal › Article
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2017
Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2016
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access32 Citations (Scopus) -
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile322 Citations (Scopus)417 Downloads (Pure) -
2019
Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
2016
Acute severe ulcerative colitis: Changing treatment paradigms
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16Research output: Contribution to journal › Article
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A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies
Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.Research output: Contribution to journal › Article
Open Access6 Citations (Scopus) -
Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study
Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2014
The role of vitamin D in gastrointestinal inflammation
Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923Research output: Contribution to journal › Review article
24 Citations (Scopus) -
2011
Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD
Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371Research output: Contribution to journal › Article
8 Citations (Scopus) -
Topical agents for idiopathic distal colitis and proctitis
Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43Research output: Contribution to journal › Article
19 Citations (Scopus)