Find Research Outputs — the UWA Profiles and Research Repository

2012

Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of elF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells

Epis, M., Giles, K., Kalinowski, F., Barker, A., Cohen, R. & Leedman, P., Oct 2012, In : Journal of Biological Chemistry. 287, p. 35251-35259

Research output: Contribution to journal › Article

Open Access

40 Citations (Scopus)

2016

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journal › Article

9 Citations (Scopus)

2012

ADAM28 is elevated in humans with the metabolic syndrome and is a novel sheddase of human tumour necrosis factor-alpha

Jowett, J. B. M., Okada, Y., Leedman, P., Curran, J. E., Johnson, M. P., Moses, E., Goring, H. H. H., Mochizuki, S., Blangero, J., Stone, L., Allen, H., Mitchell, C. & Matthews, V., 25 Sep 2012, In : Immunology and Cell Biology. 90, 10, p. 966-973

Research output: Contribution to journal › Article

Open Access

File

12 Citations (Scopus)

247 Downloads (Pure)

2014

A case of iatrogenic cushing syndrome and apparent mineralocorticoid excess presenting with accelerated hypertension and proteinuria

Kong, W. Y., Leedman, P. & Irish, A., 2014, In : Internal Medicine Journal. 44, 9, p. 932-934

Research output: Contribution to journal › Letter

2011

The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

Epis, M., Barker, A. P., Giles, K., Beveridge, D. & Leedman, P., 2011, In : The Journal of Biological Chemistry. 286, 48, p. 41442-41454

Research output: Contribution to journal › Article

66 Citations (Scopus)

2019

Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development

Woo, A., Patry, C-A. A., Ghamari, A., Pregernig, G., Yuan, D., Zheng, K., Piers, T., Hibbs, M., Li, J. K., Fidalgo, M., Wang, J. Y., Lee, J-H., Leedman, P., Wang, J., Fraenkel, E. & Cantor, A. B., 27 Aug 2019, In : Blood advances. 3, 16, p. 2499-2511 13 p.

Research output: Contribution to journal › Article

Open Access

2016

Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer

Hoyne, G., Rudnicka, C., Sang, Q. X., Roycik, M., Howarth, S., Leedman, P., Schlaich, M., Candy, P. & Matthews, V., 2016, In : BMC Cancer. 16, 12 p., 151.

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

2017

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

Epis, M. R., Giles, K. M., Beveridge, D. J., Richardson, K. L., Candy, P. A., Stuart, L. M., Bentel, J., Cohen, R. J. & Leedman, P. J., 2017, In : Oncotarget. 8, 33, p. 55116-55134 19 p.

Research output: Contribution to journal › Article

Open Access

14 Citations (Scopus)

2016

The log TSH-free T4 relationship in a community-based cohort is nonlinear and is influenced by age, smoking and thyroid peroxidase antibody status.

Brown, S. J., Bremner, A., Hadlow, N. C., Feddema, P., Leedman, P., O'Leary, P. & Walsh, J., Nov 2016, In : Clinical Endocrinology. 85, 5, p. 789-796

Research output: Contribution to journal › Article

Open Access

22 Citations (Scopus)

2019

Modulation of miRNA function by natural and synthetic RNA-binding proteins in cancer

Vos, P. D., Leedman, P. J., Filipovska, A. & Rackham, O., Oct 2019, In : Cellular and Molecular Life Sciences. 76, 19, p. 3745–3752

Research output: Contribution to journal › Review article

12 Citations (Scopus)

2012

Contribution of the first K-homology domain of poly(C)-binding protein 1 to its affinity and specificity for C-rich oligonucleotides

Yoga, Y. M. K., Traore, D. A. K., Sidiqi, M., Szeto, C., Pendini, N. R., Barker, A., Leedman, P., Wilce, J. A. & Wilce, M. C. J., 2012, In : Nucleic Acids Research. 40, p. 5101-5114

Research output: Contribution to journal › Article

Open Access

25 Citations (Scopus)

2015

Clinical potential of microRNA-7 in cancer.

Horsham, J., Kalinowski, F., Epis, M., Ganda, C., Brown, R. & Leedman, P., 2015, In : Journal of Clinical Medicine. 4, 9, p. 1668-1687

Research output: Contribution to journal › Article

Open Access

2014

Breast cancer prognosis predicted by nuclear receptor-coregulator networks

Doan, T. B., Eriksson, N. A., Graham, D., Funder, J. W., Simpson, E. R., Kuczek, E. S., Clyne, C., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., Jul 2014, In : Molecular Oncology. 8, 5, p. 998-1013

Research output: Contribution to journal › Article

Open Access

14 Citations (Scopus)

2011

MicroRNA Regulation of Growth Factor Receptor Signaling in Human Cancer Cells

Giles, K., Barker, A. P., Zhang, P., Epis, M. & Leedman, P., 2011, MicroRNA and Cancer: Methods and Protocols. Wu, W. (ed.). 1st Edition ed. United States: Humana Press, p. 147-163

Research output: Chapter in Book/Conference paper › Other chapter contribution

30 Citations (Scopus)

2012

Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7

Kalinowski, F., Giles, K., Candy, P. A., Ali, A., Ganda, C., Epis, M., Webster, R. & Leedman, P., 24 Oct 2012, In : PLoS One. 7, p. 1-16

Research output: Contribution to journal › Article

Open Access

53 Citations (Scopus)

Protein arginine methyltransferase 6-dependent gene expression and splicing: association with breast cancer outcomes

Dowhan, D. H., Harrison, M. J., Eriksson, N. A., Bailey, P., Pearen, M. A., Fuller, P. J., Funder, J. W., Simpson, E. R., Leedman, P., Tilley, W. D., Brown, M. A., Clarke, C. L. & Muscat, G. E. O., 2012, In : Endocrine-Related Cancer. 19, p. 509-526

Research output: Contribution to journal › Article

18 Citations (Scopus)

miRNA-7-5p inhibits melanoma cell migration and invasion

Giles, K., Brown, R., Epis, M., Kalinowski, F. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 430, p. 706-710

Research output: Contribution to journal › Article

64 Citations (Scopus)

2014

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Hilton, H. N., Graham, J. D., Oakes, S. R., Silvestri, A., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, p. 8651-8664

Research output: Contribution to journal › Article

20 Citations (Scopus)

PRMT2 and RORy Expression Are Associated With Breast Cancer Survival Outcomes

Oh, T. G., Bailey, P., Dray, E., Smith, A. G., Goode, J., Eriksson, N., Funder, J. W., Fuller, P. J., Simpson, E. R., Tilley, W. D., Leedman, P., Clarke, C. L., Grimmond, S., Dowhan, D. H. & Muscat, G. E. O., 2014, In : Molecular Endocrinology. 28, p. 1166-1185

Research output: Contribution to journal › Article

27 Citations (Scopus)

2011

miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion

Thomson, D., Giles, K., Maleki, S., Mreich, E., Wheeler, H., Leedman, P., Biggs, M., Cook, R., Little, N., Robinson, B., Mcdonald, K. & Fowler, A., 2011, In : European Journal of Cancer. 47, 6, p. 953-963

Research output: Contribution to journal › Article

99 Citations (Scopus)

A meta-analysis of the associations between common variation in the PDE8B gene and thyroid hormone parameters, including assessment of longitudinal stability of associations over time and effect of thyroid hormone replacement

Taylor, P. N., Panicker, V., Sayers, A., Shields, B., Iqbal, A., Bremner, A., Beilby, J., Leedman, P., Hattersley, A. T., Vaidya, B., Frayling, T., Evans, J., Timpson, N. J., Tobias, J. H., Walsh, J. & Dayan, C. M., 2011, In : European Journal of Endocrinology. 164, p. 773-780

Research output: Contribution to journal › Article

26 Citations (Scopus)

2016

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-?B

Giles, K., Brown, R. A., Ganda, C., Podgorny, M., Candy, P., Wintle, L. C., Richardson, K. L., Kalinowski, F. C., Stuart, L. M., Epis, M. R., Haass, N. K., Herlyn, M. & Leedman, P. J., 2016, In : Oncotarget. 7, 22, p. 31663-31680 18 p.

Research output: Contribution to journal › Article

Open Access

46 Citations (Scopus)

2020

Direct in vivo comparison of [¹⁸F]PSMA-1007 with [⁶⁸Ga]Ga-PSMA-11 and [¹⁸F]AlF-PSMA-11 in mice bearing PSMA-expressing xenografts

Ioppolo, J. A., Nezich, R. A., Richardson, K. L., Morandeau, L., Leedman, P. J. & Price, R. I., Jul 2020, In : Applied Radiation and Isotopes. 161, 109164.

Research output: Contribution to journal › Article

2 Citations (Scopus)

2012

Significant association between thyroid hormones and erythrocyte indices in euthyroid subjects

Bremner, A., Feddema, P., Joske, D., Leedman, P., O'Leary, P., Olynyk, J. & Walsh, J., 2012, In : Clinical Endocrinology. 76, p. 304-311

Research output: Contribution to journal › Article

35 Citations (Scopus)

Age-Related Changes in Thyroid Function: A Longitudinal Study of a Community-Based Cohort

Bremner, A., Feddema, P., Leedman, P., Brown, S. J., Beilby, J., Lim, E., Wilson, S., O'Leary, P. & Walsh, J., 2012, In : Journal of Clinical Endocrinology & Metabolism. 97, 5, p. 1554-1562

Research output: Contribution to journal › Article

160 Citations (Scopus)

2015

MicroRNA-7: A miRNA with expanding roles in development and disease

Horsham, J., Ganda, C., Kalinowski, F., Brown, R., Epis, M. & Leedman, P., 2015, In : International Journal of Biochemistry and Cell Biology. 69, p. 215-224

Research output: Contribution to journal › Review article

48 Citations (Scopus)

2012

Sequence requirements for RNA binding by HuR and AUF1

Barker, A., Epis, M., Porter, C. J., Hopkins, B. R., Wilce, M. C. J., Giles, K. & Leedman, P., 2012, In : Journal of Biochemistry. 151, p. 423-437

Research output: Contribution to journal › Article

43 Citations (Scopus)

Matrigel Basement Membrane Matrix influences expression of microRNAs in cancer cell lines

Price, K., Tsykin, A., Giles, K., Sladic, R. T., Epis, M., Ganss, R., Goodall, G. J. & Leedman, P., 2012, In : Biochemical and Biophysical Research Communications. 427, p. 343-348

Research output: Contribution to journal › Article

29 Citations (Scopus)

2014

microRNA-7: a tumor suppressor miRNA with therapeutic potential

Kalinowski, F., Brown, R., Ganda, C., Giles, K. M., Epis, M., Horsham, J. & Leedman, P., Sep 2014, In : International Journal of Biochemistry and Cell Biology. 54, p. 312-317

Research output: Contribution to journal › Article

79 Citations (Scopus)

miR-331-3p regulates expression of neuropilin-2 in glioblastoma

Epis, M., Giles, K., Candy, P., Webster, R. & Leedman, P., Jan 2014, In : Journal of Neuro-Oncology. 116, 1, p. 67-75

Research output: Contribution to journal › Article

Open Access

51 Citations (Scopus)

2012

Nuclear Pore Component Nup98 Is a Potential Tumor Suppressor and Regulates Posttranscriptional Expression of Select p53 Target Genes

Singer, S., Zhao, R., Barsotti, A. M., Ouwehand, A., Fazollahi, M., Coutavas, E., Breuhahn, K., Neumann, O., Longerich, T., Pusterla, T., Powers, M. A., Giles, K., Leedman, P., Hess, J., Grunwald, D., Bussemaker, H. J., Singer, R. H., Schirmacher, P. & Prives, C., 2012, In : Molecular Cell. 48, p. 799-810

Research output: Contribution to journal › Article

Open Access

43 Citations (Scopus)

2019

ETS1 induces transforming growth factor β signaling and promotes epithelial-to-mesenchymal transition in prostate cancer cells

Australian Prostate Cancer BioResource, Jan 2019, In : Journal of Cellular Biochemistry. 120, 1, p. 848-860 13 p.

Research output: Contribution to journal › Article

6 Citations (Scopus)

2014

Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease

Medici, M., Porcu, E., Pistis, G., Teumer, A., Brown, S. J., Jensen, R. A., Rawal, R., Roef, G. L., Plantinga, T. S., Vermeulen, S. H., Lahti, J., Simmonds, M. J., Husemoen, L. L. N., Freathy, R. M., Shields, B. M., Pietzner, D., Nagy, R., Broer, L., Chaker, L., Korevaar, T. I. M. & 98 others, Plia, M. G., Sala, C., Voelker, U., Richards, J. B., Sweep, F. C., Gieger, C., Corre, T., Kajantie, E., Thuesen, B., Taes, Y. E., Visser, W. E., Hattersley, A. T., Kratzsch, J., Hamilton, A., Li, W., Homuth, G., Lobina, M., Mariotti, S., Soranzo, N., Cocca, M., Nauck, M., Spielhagen, C., Ross, A., Arnold, A., van de Bunt, M., Liyanarachchi, S., Heier, M., Grabe, H. J., Masciullo, C., Galesloot, T. E., Lim, E. M., Reischl, E., Leedman, P. J., Lai, S., Delitala, A., Bremner, A. P., Philips, D. I. W., Beilby, J. P., Mulas, A., Vocale, M., Abecasis, G., Forsen, T., James, A., Widen, E., Hui, J., Prokisch, H., Rietzschel, E. E., Palotie, A., Feddema, P., Fletcher, S. J., Schramm, K., Rotter, J. I., Kluttig, A., Radke, D., Traglia, M., Surdulescu, G. L., He, H., Franklyn, J. A., Tiller, D., Vaidya, B., de Meyer, T., Jorgensen, T., Eriksson, J. G., O'Leary, P. C., Wichmann, E., Hermus, A. R., Psaty, B. M., Ittermann, T., Hofman, A., Bosi, E., Schlessinger, D., Wallaschofski, H., Pirastu, N., Aulchenko, Y. S., de la Chapelle, A., Netea-Maier, R. T., Gough, S. C. L., Meyer zu Schwabedissen, H., Frayling, T. M., Kaufman, J-M., Linneberg, A., Raeikkoenen, K., Smit, J. W. A., Kiemeney, L. A., Rivadeneira, F., Uitterlinden, A. G., Walsh, J. P., Meisinger, C., Den Heijer, M., Visser, T. J., Spector, T. D., Wilson, S. G., Voelzke, H., Cappola, A., Toniolo, D., Sanna, S., Naitza, S. & Peeters, R. P., Feb 2014, In : PLoS Genetics. 10, 2, p. 1-13 13 p., e1004123.

Research output: Contribution to journal › Article

Open Access

98 Citations (Scopus)

2020

Altered Iron Metabolism and Impact in Cancer Biology, Metastasis, and Immunology

Brown, R. A. M., Richardson, K. L., Kabir, T. D., Trinder, D., Ganss, R. & Leedman, P. J., 9 Apr 2020, In : Frontiers in Oncology. 10, 476.

Research output: Contribution to journal › Review article

Open Access

6 Citations (Scopus)

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