Find Research Outputs — the UWA Profiles and Research Repository

2013

Vedolizumab as induction and maintenance therapy for Crohn's disease

GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.

Research output: Contribution to journal › Article

2016

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study

Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, Halfvarson, J., Hov, J. R., Huang, H., Kennedy, N. A., Kupcinskas, L., Lawrance, I., Lee, J. C., Satsangi, J., Schreiber, S., Théâtre, E., Van Der Meulen-De Jong, A. E., Weersma, R. K., Wilson, D. C., Parkes, M., Vermeire, S., Rioux, J. D., Mansfield, J., Silverberg, M. S., Radford-Smith, G., Mcgovern, D. P. B., Barrett, J. C. & Lees, C. W., 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.

Research output: Contribution to journal › Article

Open Access

File

322 Citations (Scopus)

418 Downloads (Pure)

2013

Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era

Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498

Research output: Contribution to journal › Article

20 Citations (Scopus)

2019

Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission

Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.

Research output: Contribution to journal › Article

Open Access

Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome

Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.

Research output: Contribution to journal › Review article

1 Citation (Scopus)

2012

NAFLD, the changing face of IBD

Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study

Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293

Research output: Contribution to journal › Article

13 Citations (Scopus)

2011

Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention

Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708

Research output: Contribution to journal › Article

Open Access

9 Citations (Scopus)

2013

Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice

Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12pp

Research output: Contribution to journal › Article

Open Access

39 Citations (Scopus)

2012

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, Achkar, J-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Büning, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Glas, J., Haritunians, T., Hart, A., Hawkey, C., Hedl, M., Hu, X., Karlsen, T. H., Kupcinskas, L., Kugathasan, S., Latiano, A., Laukens, D., Lawrance, I., Lees, C. W., Louis, E., Mahy, G., Mansfield, J., Morgan, A. R., Mowat, C., Newman, W., Palmieri, O., Ponsioen, C. Y., Potocnik, U., Prescott, N. J., Regueiro, M., Rotter, J. I., Russell, R. K., Sanderson, J. D., Sans, M., Satsangi, J., Schreiber, S., Simms, L. A., Sventoraityte, J., Targan, S. R., Taylor, K. D., Tremelling, M., Verspaget, H. W., De Vos, M., Wijmenga, C., Wilson, D. C., Winkelmann, J., Xavier, R. J., Zeissig, S., Zhang, B., Zhang, C. K., Zhao, H., Silverberg, M. S., Annese, V., Hakonarson, H., Brant, S. R., Radford-Smith, G., Mathew, C. G., Rioux, J. D., Schadt, E. E., Daly, M. J., Franke, A., Parkes, M., Vermeire, S., Barrett, J. C. & Cho, J. H., 1 Nov 2012, In : Nature. 491, 7422, p. 119-124

Research output: Contribution to journal › Article

2625 Citations (Scopus)

2014

Preventing infective complications in inflammatory bowel disease

Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698

Research output: Contribution to journal › Review article

Open Access

9 Citations (Scopus)

2013

Crohn's disease and smoking: Is it ever too late to quit?

Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671

Research output: Contribution to journal › Article

29 Citations (Scopus)

Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease

Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245

Research output: Contribution to journal › Article

26 Citations (Scopus)

2011

Topical agents for idiopathic distal colitis and proctitis

Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43

Research output: Contribution to journal › Article

19 Citations (Scopus)

Predictors of fibrostenotic Crohn's Disease

Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007

Research output: Contribution to journal › Article

47 Citations (Scopus)

2014

Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD

Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165

Research output: Contribution to journal › Review article

95 Citations (Scopus)

2016

Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection

Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, Lawrance, I., Radford-Smith, G., Sloss, A., Sorrentino, D., Gassner, S., Haas, T., Reicht, G., Reinisch, W., Strasser, M., Vogelsang, H., Bossuyt, P., Dewit, O., D'Haens, G., Franchimont, D., Louis, E., Vermeire, S., Bernstein, C. N., Bourdages, R., Chiba, N., Dhalla, S. S., Feagan, B. G., Fedorak, R. N., Lachance, J. R., Panaccione, R., Ropeleski, M., Singh Salh, B., Lukas, M., Colombel, J. F., Allez, M., Desreumaux, P., Dupas, J. L., Grimaud, J. C., Hebuterne, X., Laharie, D., Lerebours, E., Peyrin-Biroulet, L., Reimund, J. M., Viennot, S., Zerbib, F., Antoni, C., Atreya, R., Baumgart, D. C., Berg, C., Boecker, U., Bramkamp, G., Bünning, C., Ehehalt, R., Howaldt, S., Kucharzik, T., Lamprecht, H. G., Mudter, J., Preiss, J. C., Schreiber, S., Seidler, U., Altorjay, I., Banai, J., Lakatos, P. L., Varga, M., Vincze, A., Avni-Biron, I., Fishman, S., Fraser, G. M., Goldin, E., Rachmilewitz, D., Annese, V., Ardizzone, S., Biancone, L., Bossa, F., Danese, S., Fries, W., Gionchetti, P., Maconi, G., Terrosu, G., Usai, P., D'Haens, G. R., Gearry, R. B., Hill, J., Rowbotham, D. S., Schultz, M., Stubbs, R. S., Wallace, D., Walmsley, R. S., Wyeth, J., Malecka-Panas, E., Paradowski, L., Regula, J., Beales, I. P., Campbell, S., Hawthorne, A. B., Parkes, M., Travis, S. P., Achkar, J. P., Behm, B. W., Bickston, S. J., Brown, K. J., Chiorean, M. V., Devilliers, W. J. S., Elliott, D. E., Grunkmeier, D., Hamilton, J. W., Hanauer, S. B., Hanson, J. S., Hardi, R., Helper, D. J., Herfarth, H., Higgins, P. D. R., Holderman, W. H., Kottoor, R., Kreines, M. D., Leman, B. I., Li, X., Loftus, E. V., Noar, M., Oikonomou, I., Onken, J., Peterson, K. A., Phillips, R. P., Randall, C. W., Ricci, M., Ritter, T., Rubin, D. T., Safdi, M., Sandborn, W. J., Sauberman, L., Scherl, E., Schwarz, R. P., Sedghi, S., Shafran, I., Sninsky, C. A., Stein, I., Swoger, J., Vecchio, J., Weinberg, D. I., Wruble, L. D., Yajnik, V. & Younes, Z., 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.

Research output: Contribution to journal › Article

Open Access

114 Citations (Scopus)

2013

Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis

Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, Mcgovern, D. P. B., Radford-Smith, G. L., Schreiber, S., Schumm, P. L., Sharma, Y., Silverberg, M. S., Weersma, R. K., D'Amato, M., Vermeire, S., Franke, A., Lettre, G., Xavier, R. J., Daly, M. J., Rioux, J. D., Aumais, G., Bernard, E. J., Cohen, A. Y., Deslandres, C., Lahaie, R. G., Paré, P., Cho, J. H., Targan, S. R., Schumm, P. P., Rutgeerts, P. J., Vermeire, S. A. F. A., Steinhart, A. H., Ahmad, T., Anderson, C. A., Baldassano, R. N., Balschun, T., Barclay, M. L., Barrett, J. C., Bayless, T. M., Bis, J. C. M., Brand, S., Bumpstead, S., Büning, C., Cohen, A., Colombel -, J. F., Cottone, M., D'Incà, R., Denson, T., Dubinsky, M. C., Edwards, C. M., Florin, T. H. J., Franchimont, D. P., Gearry, R. B., Georges, M. A. J. A. J., Glas, J., Van Gossum, A., Griffiths, A. M., Guthery, S. L., Hákonarson, H. H., Haritunians, T., Hugot, J. P., De Jong, D. J., Jostins, L., Kugathasan, S., Kullak- Ublick, G. A., Latiano, A., Laukens, D., Lawrance, I., Lee, J., Lees, C. W., Lémann, M., Levine, A. D., Libioulle, C., Louis, É. J., Mansfield, J. C., Mathew, C. G. P., Mitrovič, M., Montgomery, G. W., Mowat, C. E., Newman, W. G., Palmieri, O., Panés, J., Parkes, M., Phillips, A. M., Ponsioen, C. Y. J., Potočnik, U., Prescott, N. J., Proctor, D. D., Regueiro, M. D., Roberts, R. L., Rotter, J. I., Sanderson, J. D., Sans, M., Satsangi, J., Seibold, F., Simms, L. A., Taylor, K. D., Verspaget, H. W., De Vos, M. P., Walters, T. D., Wang, K., Whiteman, D. C. & Wijmenga, C., 2013, In : PLoS Genetics. 9, 9, p. 11 pp.

Research output: Contribution to journal › Article

Open Access

112 Citations (Scopus)

2016

Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease

Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, Dunckley, P., Gaya, D. R., Gearry, R., Gore, S., Halfvarson, J., Hart, A., Hawkey, C. J., Hoentjen, F., Iqbal, T., Irving, P., Lal, S., Lawrence, I., Lees, C. W., Lewis, S., Lockett, M., Mann, S., Mansfield, J., Mowat, C., Muller, F., Murray, C., Orchard, T., Parkes, M., Phillips, R., Pollok, R., Radford-Smith, G., Sebastian, S., Sen, S., Shirazi, T., Silverberg, M., Solomon, L., Sturniolo, G. C., Thomas, M., Tremelling, M., Tsianos, E. V., Watts, D., Weaver, S., Wesley, E., Holden, A., D'Souza, R., Mulgrew, C. J., Oram, R., Weersma, R. K. & Ahmad, T., 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.

Research output: Contribution to journal › Article

38 Citations (Scopus)

2019

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.

Research output: Contribution to journal › Article

Open Access

13 Citations (Scopus)

2016

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.

Research output: Contribution to journal › Article

251 Citations (Scopus)

2014

The role of vitamin D in gastrointestinal inflammation

Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923

Research output: Contribution to journal › Review article

24 Citations (Scopus)

What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258

Research output: Contribution to journal › Article

Open Access

9 Citations (Scopus)

The importance of validating proposed genetic profiles in IBD

Lawrance, I., May 2014, In : Journal of Internal Medicine.

Research output: Contribution to journal › Review article

Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response

Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.

Research output: Contribution to journal › Article

1 Citation (Scopus)

2020

The role of a plant-based diet in the pathogenesis, etiology and management of the inflammatory bowel diseases

Grosse, C. S. J., Christophersen, C. T., Devine, A. & Lawrance, I. C., 3 Mar 2020, In : Expert Review of Gastroenterology and Hepatology. 14, 3, p. 137-145 9 p.

Research output: Contribution to journal › Review article

2 Citations (Scopus)

2011

SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer

Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13pp

Research output: Contribution to journal › Article

Open Access

45 Citations (Scopus)

2018

Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer

Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.

Research output: Contribution to journal › Article

10 Citations (Scopus)

Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease

Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-Smith, G., Andrews, J. M. & 2 others, McHugh, P. C. & Barclay, M. L., 29 Nov 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.

Research output: Contribution to journal › Article

2016

Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements

Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.

Research output: Contribution to journal › Editorial

Open Access

32 Citations (Scopus)

2011

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Haritunians, T., Jostins, L., Latiano, A., Mathew, C. G., Montgomery, G. W., Prescott, N. J., Rotter, J. I., Schumm, P., Sharma, Y., Simms, L. A., Taylor, K. D., Whiteman, D., Wijmenga, C., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Bunning, C., Cohen, A., Colombel, J-F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S. L., Halfvarson, J., Hommes, D., Hugot, J-P., Laukens, D., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D. D., Regueiro, M., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A. H., Stokkers, P. C. F., Torkvist, L., Kullak-Ublick, G., Walters, T., Targan, S. R., Brant, S. R., Rioux, J. D., D'Amato, M., Weersma, R., Kutharthasan, S., Griffiths, A. M., Mansfield, J. C., Vermeire, S., Duerr, R. H., Silverberg, M. S., Satsangi, J., Schreiber, S., Cho, J. H., Annese, V., Hakonarson, H. & Parkes, M., 2011, In : PLoS Genetics. 7, 1, p. 13pp

Research output: Contribution to journal › Article

Open Access

349 Citations (Scopus)

2019

Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series

Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120

Research output: Contribution to journal › Abstract/Meeting Abstract

2020

Anti-TNF Therapy in Pregnant Women with Inflammatory Bowel Disease: Effects of Therapeutic Strategies on Disease Behavior and Birth Outcomes

Julsgaard, M., Hvas, C. L., Gearry, R. B., Gibson, P. R., Fallingborg, J., Sparrow, M. P., Bibby, B. M., Connell, W. R., Brown, S. J., Kamm, M. A., Lawrance, I. C., Vestergaard, T., Svenningsen, L., Baekdal, M., Kammerlander, H., Walsh, A., Boysen, T., Bampton, P., Radford-Smith, G., Kjeldsen, J. & 10 others, Andrews, J. M., Subramaniam, K., Moore, G. T., Jensen, N. M., Connor, S. J., Wildt, S., Wilson, B., Ellard, K., Christensen, L. A. & Bell, S. J., Jan 2020, In : Inflammatory Bowel Diseases. 26, 1, p. 93-102 10 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

2016

The multidisciplinary team

Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17

Research output: Contribution to journal › Article

2 Citations (Scopus)

2014

Detection of liver injury in IBD using transient elastography

Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677

Research output: Contribution to journal › Article

9 Citations (Scopus)

2016

Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study

Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.

Research output: Contribution to journal › Article

Open Access

9 Citations (Scopus)

2012

Microbiota and management of inflammatory bowel disease

Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140

Research output: Contribution to journal › Review article

3 Citations (Scopus)

2013

A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents

Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935

Research output: Contribution to journal › Article

11 Citations (Scopus)

2016

A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

Research output: Contribution to journal › Article

Open Access

6 Citations (Scopus)

2011

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, Colombel, J-F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J-P., Jobin, G., Laukens, D., Lawrance, I., Lémann, M., Levine, A., Libioulle, C., Louis, E., Mcgovern, D. P., Milla, M., Montgomery, G. W., Morley, K. I., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panés, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L., Seielstad, M., Hillary Steinhart, A., Targan, S. R., Van Den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H-J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S. R., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., 2011, In : Nature Genetics. 43, 3, p. 246-252

Research output: Contribution to journal › Article

928 Citations (Scopus)

Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study

Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193

Research output: Contribution to journal › Article

99 Citations (Scopus)

2019

Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients

Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.

Research output: Contribution to journal › Article

Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series

Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.

Research output: Contribution to journal › Abstract/Meeting Abstract

2012

Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease

Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984

Research output: Contribution to journal › Review article

5 Citations (Scopus)

2014

HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, Fedorak, R. N., Florin, T. H., Gaya, D. R., Greig, E., Halfvarson, J., Hart, A., Irving, P., Jones, G., Karban, A., Lawrance, I., Lee, J. C., Lees, C., Lev-Tzion, R., Lindsay, J. O., Mansfield, J., Mawdsley, J., Mazhar, Z., Parkes, M., Parnell, K., Orchard, T. R., Radford-Smith, G., Russell, R. K., Reffitt, D., Satsangi, J., Silverberg, M. S., Sturniolo, G. C., Tremelling, M., Tsianos, V., Van Heel, D. A., Walsh, A., Watermeyer, G., Weersma, R. K., Zeissig, S., Rossjohn, J., Holden, A. L., International Serious Adverse Events Consortium, I. S. A. E. C., Ibd Pharmacogenetics Study Group, IBD. P. S. G. & Ahmad, T., 2014, In : Nature Genetics. 46, 10, p. 1131-1136

Research output: Contribution to journal › Article

104 Citations (Scopus)

2016

Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection

Julsgaard, M., Christensen, L. A., Gibson, P. R., Gearry, R. B., Fallingborg, J., Hvas, C. L., Bibby, B. M., Uldbjerg, N., Connell, W. R., Rosella, O., Grosen, A., Brown, S. J., Kjeldsen, J., Wildt, S., Svenningsen, L., Sparrow, M. P., Walsh, A., Connor, S. J., Radford-Smith, G., Lawrance, I. & 3 others, Andrews, J. M., Ellard, K. & Bell, S. J., 2016, In : Gastroenterology. 151, 1, p. 110-119

Research output: Contribution to journal › Article

129 Citations (Scopus)

2014

Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function

Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616

Research output: Contribution to journal › Article

5 Citations (Scopus)

2011

Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD

Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371

Research output: Contribution to journal › Article

8 Citations (Scopus)

2018

Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease

Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, Gearry, R. B., Selby, W., Bell, S. J., Brown, S. J. & Connell, W. R., 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.

Research output: Contribution to journal › Article

5 Citations (Scopus)

High Dose Vitamin D supplementation alters faecal microbiome and predisposes mice to more severe colitis

Ghaly, S., Kaakoush, N. O., Lloyd, F., McGonigle, T., Mok, D., Baird, A., Klopcic, B., Gordon, L., Gorman, S., Forest, C., Bouillon, R., Lawrance, I. C. & Hart, P. H., 1 Dec 2018, In : Scientific Reports. 8, 1, 11511.

Research output: Contribution to journal › Article

Open Access

18 Citations (Scopus)

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