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2014
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927Research output: Contribution to journal › Letter
7 Citations (Scopus) -
2019
Level of UV Exposure, Skin Type, and Age Are More Important than Thiopurine Use for Keratinocyte Carcinoma Development in IBD Patients
Wu, Y., Ghaly, S., Kerr, S., Jackson, B., Hanigan, K., Martins, D., Krishnaprasad, K., Mountifield, R. E., Whiteman, D. C., Bampton, P. A., Gearry, R. B., Radford-Smith, G. L. & Lawrance, I. C., 6 Sep 2019, In : Digestive Diseases and Sciences.Research output: Contribution to journal › Article
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2011
Predictors of fibrostenotic Crohn's Disease
Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007Research output: Contribution to journal › Article
48 Citations (Scopus) -
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2014
Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study
Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606Research output: Contribution to journal › Article
64 Citations (Scopus) -
2013
Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease
Walsh, A. J., Weltman, M., Burger, D., Vivekanandarajah, S., Connor, S., Howlett, M., Radford-Smith, G., Selby, W., Veillard, A. S., Grimm, M. C., Travis, S. P. L. & Lawrance, I., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, p. e449-e456Research output: Contribution to journal › Article
31 Citations (Scopus) -
2012
Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study
Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293Research output: Contribution to journal › Article
13 Citations (Scopus) -
Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease
Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984Research output: Contribution to journal › Review article
5 Citations (Scopus) -
2016
Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study
Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.Research output: Contribution to journal › Article
Open Access10 Citations (Scopus) -
2013
Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease
Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245Research output: Contribution to journal › Article
27 Citations (Scopus) -
2014
The role of vitamin D in gastrointestinal inflammation
Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923Research output: Contribution to journal › Review article
26 Citations (Scopus) -
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
2016
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access33 Citations (Scopus) -
2013
Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis
Ng, Y. L., Klopcic, B., Lloyd, F., Forrest, C., Greene, W. & Lawrance, I., 2013, In : PLoS One. 8, 10, p. 8ppResearch output: Contribution to journal › Article
Open Access16 Citations (Scopus) -
2011
Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD
Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371Research output: Contribution to journal › Article
8 Citations (Scopus) -
2018
Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice
Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.Research output: Contribution to journal › Article
Open Access14 Citations (Scopus) -
2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2018
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
The International IBD Genetics Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 2427.Research output: Contribution to journal › Article
Open Access33 Citations (Scopus) -
2011
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, , 2011, In : Nature Genetics. 43, 3, p. 246-252Research output: Contribution to journal › Article
933 Citations (Scopus) -
Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, , 2011, In : PLoS Genetics. 7, 1, p. 13ppResearch output: Contribution to journal › Article
Open Access349 Citations (Scopus) -
2013
A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents
Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935Research output: Contribution to journal › Article
11 Citations (Scopus) -
Prevention of cancer in IBD - A balancing act
Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272Research output: Contribution to journal › Review article
7 Citations (Scopus) -
2016
Acute severe ulcerative colitis: Changing treatment paradigms
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16Research output: Contribution to journal › Article
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2018
Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
2019
Anti TNFα-induced Interstitial Pneumonitis in Inflammatory Bowel Disease Patients: A Multi-Centre Western Australia Case Series
Lightowler, D., Thin, L. & Lawrance, I., 4 Sep 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, S2, p. 119-120Research output: Contribution to journal › Abstract/Meeting Abstract
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Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2016
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease
Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C., Oct 2016, In : Inflammatory Bowel Diseases. 22, 10, p. 2456-2464 9 p.Research output: Contribution to journal › Article
12 Citations (Scopus) -
2011
SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer
Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13ppResearch output: Contribution to journal › Article
Open Access45 Citations (Scopus) -
Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study
Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193Research output: Contribution to journal › Article
99 Citations (Scopus) -
2018
Vedolizumab (VDZ) real-world outcomes in ulcerative colitis (UC)
Pulusu, S. S. R., Srinivasan, A., Krishnaprasad, K., Cheng, D., Mogilevski, T., Flanagan, E., Keung, C., Wu, C., Prosser, R., Sawyer, E., Rizvi, Q. U. A., Su, H., Leung, W., Edmundson, A., Cooke, S., Mahy, G., Thin, L., Radford-Smith, G., Sparrow, M. P., Andrews, J. M. & 10 others, , 1 Feb 2018, In : Journal of Crohn's and Colitis. 12, 1, P571.Research output: Contribution to journal › Abstract/Meeting Abstract
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2019
Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome
Ghaly, S., Hart, P. H. & Lawrance, I. C., 2 Nov 2019, In : Expert Review of Gastroenterology and Hepatology. 13, 11, p. 1039-1048 10 p.Research output: Contribution to journal › Review article
1 Citation (Scopus) -
2013
Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice
Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12ppResearch output: Contribution to journal › Article
Open Access40 Citations (Scopus) -
2011
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.Research output: Contribution to journal › Article
505 Citations (Scopus) -
2013
Vedolizumab as induction and maintenance therapy for Crohn's disease
GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.Research output: Contribution to journal › Article
1054 Citations (Scopus) -
2018
Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease
Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, , 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.Research output: Contribution to journal › Article
6 Citations (Scopus) -
2016
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile330 Citations (Scopus)431 Downloads (Pure) -
2019
Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
2011
Topical agents for idiopathic distal colitis and proctitis
Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43Research output: Contribution to journal › Article
19 Citations (Scopus) -
Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program
Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465Research output: Contribution to journal › Review article
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2012
Microbiota and management of inflammatory bowel disease
Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140Research output: Contribution to journal › Review article
3 Citations (Scopus) -
2014
Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function
Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616Research output: Contribution to journal › Article
5 Citations (Scopus) -
Mechanisms of initiation and progression of intestinal fibrosis in IBD
Latella, G., Di Gregorio, J., Flati, V., Rieder, F. & Lawrance, I., 2014, In : Scandinavian Journal of Gastroenterology. 50, p. 53-65Research output: Contribution to journal › Review article
78 Citations (Scopus) -
2013
Crohn's disease and smoking: Is it ever too late to quit?
Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671Research output: Contribution to journal › Article
30 Citations (Scopus) -
2014
The importance of validating proposed genetic profiles in IBD
Lawrance, I., May 2014, In : Journal of Internal Medicine.Research output: Contribution to journal › Review article
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2013
Prevention of cancer in IBD – a balancing act
Lawrance, I., Sep 2013, In : Minerva Gastroenterologica e Dietologica.Research output: Contribution to journal › Review article
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2014
Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response
Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
2013
Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era
Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498Research output: Contribution to journal › Article
21 Citations (Scopus) -
2016
Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection
Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, , 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.Research output: Contribution to journal › Article
Open Access115 Citations (Scopus) -
2012
NAFLD, the changing face of IBD
Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.Research output: Contribution to journal › Abstract/Meeting Abstract