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2011
Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program
Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465Research output: Contribution to journal › Review article
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2013
Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease
Walsh, A. J., Weltman, M., Burger, D., Vivekanandarajah, S., Connor, S., Howlett, M., Radford-Smith, G., Selby, W., Veillard, A. S., Grimm, M. C., Travis, S. P. L. & Lawrance, I., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, p. e449-e456Research output: Contribution to journal › Article
31 Citations (Scopus) -
2016
The multidisciplinary team
Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17Research output: Contribution to journal › Article
2 Citations (Scopus) -
2013
Prevention of cancer in IBD - A balancing act
Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272Research output: Contribution to journal › Review article
7 Citations (Scopus) -
2012
Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study
Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293Research output: Contribution to journal › Article
13 Citations (Scopus) -
2014
What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?
Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2017
Dysplasia and colorectal cancer surveillance in inflammatory bowel disease
Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.Research output: Contribution to journal › Review article
9 Citations (Scopus) -
2014
Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD
Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165Research output: Contribution to journal › Review article
95 Citations (Scopus) -
2013
Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice
Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12ppResearch output: Contribution to journal › Article
Open Access39 Citations (Scopus) -
2019
Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission
Haifer, C., Lawrance, I. C., Center, J. R., Clarke, M. W., Hart, P. H., Eisman, J. A., Lucas, R. & Ghaly, S., 26 Jul 2019, In : Therapeutic Advances in Gastroenterology. 12, 12 p.Research output: Contribution to journal › Article
Open Access -
2011
Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention
Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708Research output: Contribution to journal › Article
Open Access9 Citations (Scopus) -
2017
Serologic antibodies in relation to outcome in postoperative Crohn's disease
Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, , 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.Research output: Contribution to journal › Article
8 Citations (Scopus) -
2014
Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study
Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606Research output: Contribution to journal › Article
64 Citations (Scopus) -
2016
Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements
Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.Research output: Contribution to journal › Editorial
Open Access32 Citations (Scopus) -
2012
Microbiota and management of inflammatory bowel disease
Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140Research output: Contribution to journal › Review article
3 Citations (Scopus) -
2019
Antitumor necrosis factor-alpha induced interstitial pneumonitis in patients with inflammatory bowel disease: A multicenter Western Australia case series
Lightowler, D., Thin, L. & Lawrance, I., Sep 2019, In : Journal of Gastroenterology and Hepatology. 34, p. 119-120 2 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2017
Efficacy of rectal tacrolimus for induction therapy in patients with resistant ulcerative proctitis
Lawrance, I. C., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 1 Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1248-1255 8 p.Research output: Contribution to journal › Article
25 Citations (Scopus) -
2016
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study
Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, , 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.Research output: Contribution to journal › Article
Open AccessFile315 Citations (Scopus)416 Downloads (Pure) -
2014
HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, , 2014, In : Nature Genetics. 46, 10, p. 1131-1136Research output: Contribution to journal › Article
104 Citations (Scopus) -
2011
Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents
Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418Research output: Contribution to journal › Article
56 Citations (Scopus) -
2012
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, , 1 Nov 2012, In : Nature. 491, 7422, p. 119-124Research output: Contribution to journal › Article
2619 Citations (Scopus) -
2013
European evidence based consensus for endoscopy in inflammatory bowel disease
ECCO & Lawrance, I., 15 Dec 2013, In : Journal of Crohn's and Colitis. 7, 12, p. 982-1018 37 p.Research output: Contribution to journal › Article
Open Access433 Citations (Scopus) -
2016
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, , 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.Research output: Contribution to journal › Article
38 Citations (Scopus) -
2014
PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927Research output: Contribution to journal › Letter
7 Citations (Scopus) -
Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response
Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
1 Citation (Scopus) -
Preventing infective complications in inflammatory bowel disease
Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698Research output: Contribution to journal › Review article
Open Access9 Citations (Scopus) -
Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function
Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616Research output: Contribution to journal › Article
5 Citations (Scopus) -
2013
Crohn's disease and smoking: Is it ever too late to quit?
Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671Research output: Contribution to journal › Article
29 Citations (Scopus) -
Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era
Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498Research output: Contribution to journal › Article
20 Citations (Scopus) -
Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis
Ng, Y. L., Klopcic, B., Lloyd, F., Forrest, C., Greene, W. & Lawrance, I., 2013, In : PLoS One. 8, 10, p. 8ppResearch output: Contribution to journal › Article
Open Access16 Citations (Scopus) -
2012
Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease
Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984Research output: Contribution to journal › Review article
5 Citations (Scopus) -
2014
Detection of liver injury in IBD using transient elastography
Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677Research output: Contribution to journal › Article
9 Citations (Scopus) -
2017
OP007 A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 26 Jan 2017, In : JOURNAL OF CROHNS & COLITIS. 11, 1Research output: Contribution to journal › Abstract/Meeting Abstract
Open Access -
Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study
the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.Research output: Contribution to journal › Article
23 Citations (Scopus) -
2018
Ultraviolet irradiation of skin alters the faecal microbiome independently of vitamin D in mice
Ghaly, S., Kaakoush, N. O., Lloyd, F., Gordon, L., Forest, C., Lawrance, I. C. & Hart, P. H., 11 Aug 2018, In : Nutrients. 10, 8, 1069.Research output: Contribution to journal › Article
Open Access13 Citations (Scopus) -
2017
Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis
Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.Research output: Contribution to conference › Conference presentation/ephemera
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2011
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.Research output: Contribution to journal › Article
501 Citations (Scopus) -
Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study
Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193Research output: Contribution to journal › Article
99 Citations (Scopus) -
2013
Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis
Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, , 2013, In : PLoS Genetics. 9, 9, p. 11 pp.Research output: Contribution to journal › Article
Open Access111 Citations (Scopus) -
2016
Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection
Julsgaard, M., Christensen, L. A., Gibson, P. R., Gearry, R. B., Fallingborg, J., Hvas, C. L., Bibby, B. M., Uldbjerg, N., Connell, W. R., Rosella, O., Grosen, A., Brown, S. J., Kjeldsen, J., Wildt, S., Svenningsen, L., Sparrow, M. P., Walsh, A., Connor, S. J., Radford-Smith, G., Lawrance, I. & 3 others, , 2016, In : Gastroenterology. 151, 1, p. 110-119Research output: Contribution to journal › Article
127 Citations (Scopus) -
2013
Prevention of cancer in IBD – a balancing act
Lawrance, I., Sep 2013, In : Minerva Gastroenterologica e Dietologica.Research output: Contribution to journal › Review article
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2018
Emu Oil Improves Clinical Indicators of Disease in a Mouse Model of Colitis-Associated Colorectal Cancer
Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., 2018, In : Digestive Diseases and Sciences. 63, 1, p. 135–145 11 p.Research output: Contribution to journal › Article
10 Citations (Scopus) -
Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease
Roberts, R. L., Wallace, M. C., Seinen, M. L., van Bodegraven, A. A., Krishnaprasad, K., Jones, G. T., van Rij, A. M., Baird, A., Lawrance, I. C., Prosser, R., Bampton, P., Grafton, R., Simms, L. A., Studd, C., Bell, S. J., Kennedy, M. A., Halliwell, J., Gearry, R. B., Radford-Smith, G., Andrews, J. M. & 2 others, , 29 Nov 2018, In : Inflammatory Bowel Diseases. 24, 12, p. 2606-2612 7 p.Research output: Contribution to journal › Article
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2012
NAFLD, the changing face of IBD
Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.Research output: Contribution to journal › Abstract/Meeting Abstract
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2016
Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection
Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, , 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.Research output: Contribution to journal › Article
Open Access111 Citations (Scopus) -
2018
Anti-TNF therapeutic drug monitoring in postoperative Crohn's disease
Wright, E. K., Kamm, M. A., De Cruz, P., Hamilton, A. L., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Prideaux, L., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Jakobovits, S. L., Florin, T. H., Gibson, P. R., Debinski, H., Macrae, F. A., Samuel, D., Kronborg, I., Radford-Smith, G. & 5 others, , 25 May 2018, In : Journal of Crohn's and Colitis. 12, 6, p. 653-661 9 p.Research output: Contribution to journal › Article
4 Citations (Scopus) -
2019
Emu Oil reduces disease severity in a mouse model of chronic ulcerative colitis
Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., 4 Mar 2019, In : Scandinavian Journal of Gastroenterology. 54, 3, p. 273-280 8 p.Research output: Contribution to journal › Article
3 Citations (Scopus) -
2016
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.Research output: Contribution to journal › Article
248 Citations (Scopus) -
2013
Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease
International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I. C., 6 Jun 2013, In : American Journal of Human Genetics. 92, 6, p. 1008-1012 5 p.Research output: Contribution to journal › Article
Open Access87 Citations (Scopus)