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• 2020

  Integrated Guidance for Enhancing the Care of Familial Hypercholesterolaemia in Australia

  FH Australasia Network Consensus Working Group, Watts, G. F., Sullivan, D. R., Hare, D. L., Kostner, K. M., Horton, A. E., Bell, D. A., Brett, T., Trent, R. J., Poplawski, N. K., Martin, A. C., Srinivasan, S., Justo, R. N., Chow, C. K., Pang, J., Ademi, Z., Ardill, J. J., Barnett, W., Bates, T. R., Beilin, L. J. & 65 others, Bishop, W., Black, J. A., Brett, P., Brown, A., Burnett, J. R., Bursill, C. A., Colley, A., Clifton, P. M., Ekinci, E. I., Elias, L., Figtree, G. A., Forge, B. H., Garton-Smith, J., Graham, D. F., Hamilton-Craig, I., Hamilton-Craig, C. R., Heal, C., Hespe, C. M., Hooper, A. J., Howes, L. G., Ingles, J., Irwin, J., Janus, E. D., Kangaharan, N., Keech, A. C., Kirke, A. B., Kritharides, L., Kyle, C. V., Lacaze, P., Lambert, K., Li, S. C. H., Malan, W., Maticevic, S., McQuillan, B. M., Mirzaee, S., Mori, T. A., Morton, A. C., Colquhoun, D. M., Moullin, J. C., Nestel, P. J., Nowak, K. J., O'Brien, R. C., Pachter, N., Page, M. M., Pedrotti, A., Psaltis, P. J., Radford, J., Reid, N. J., Robertson, E. N., Ryan, J. D. M., Sarkies, M. N., Schultz, C. J., Scott, R. S., Semsarian, C., Simons, L. A., Spinks, C., Tonkin, A. M., van Bockxmeer, F., Waddell-Smith, K. E., Ward, N. C., White, H. D., Wilson, A. M., Winship, I., Woodward, A. M. & Nicholls, S. J., 2020, (Accepted/In press) In : Heart Lung and Circulation.

  Research output: Contribution to journal › Article

  Open Access

  • Hyperlipoproteinemia Type II
  • LDL Cholesterol
  • Proprotein Convertase 9
  • Ezetimibe
  • Blood Component Removal

• Mechanisms of the protective effects of nitrate and nitrite in cardiovascular and metabolic diseases

  Liu, G., Croft, K., Hodgson, J., Mori, T. & Ward, N., 1 Mar 2020, In : Nitric Oxide - Biology and Chemistry. 96, p. 35-43

  Research output: Contribution to journal › Review article
  2 Citations (Scopus)

• Quantifying dietary vitamin K and its link to cardiovascular health: a narrative review

  Palmer, C. R., Blekkenhorst, L. C., Lewis, J. R., Ward, N. C., Schultz, C. J., Hodgson, J. M., Croft, K. D. & Sim, M., 16 Mar 2020, In : Food & function.

  Research output: Contribution to journal › Review article

  • vitamin K
  • Vitamin K
  • Vitamin K 1
  • Vitamin K 2
  • phylloquinone
  2 Citations (Scopus)

• Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation

  Perks, K. L., Ferreira, N., Ermer, J. A., Rudler, D. L., Richman, T. R., Rossetti, G., Ward, N. C., Matthews, V. B., Ward, N. C., Rackham, O. & Filipovska, A., 15 Oct 2020, In : Aging. 12, 19, p. 19677-19695 19 p.

  Research output: Contribution to journal › Article

  • Mitochondrial Proteins
  • High Fat Diet
  • Organelle Biogenesis
  • Diet
  • Inflammation

• SGLT2 Inhibitor–Induced Sympathoinhibition: A Novel Mechanism for Cardiorenal Protection

  Herat, L. Y., Magno, A. L., Rudnicka, C., Hricova, J., Carnagarin, R., Ward, N. C., Arcambal, A., Kiuchi, M. G., Head, G. A., Schlaich, M. P. & Matthews, V. B., Feb 2020, In : JACC: Basic to Translational Science. 5, 2, p. 169-179 11 p.

  Research output: Contribution to journal › Article

  Open Access

  • Sodium-Glucose Transport Proteins
  • Blood Pressure
  • Sympathetic Nervous System
  • Tyrosine 3-Monooxygenase
  • Denervation
  19 Citations (Scopus)

• Sodium glucose co-transporter 2 inhibition reduces succinate levels in diabetic mice

  Herat, L. Y., Ward, N. C., Magno, A. L., Rakoczy, E. P., Kiuchi, M. G., Schlaich, M. P. & Matthews, V. B., 21 Jun 2020, In : World Journal of Gastroenterology. 26, 23, p. 3225-3235 11 p.

  Research output: Contribution to journal › Article

  Open Access

  • Sodium-Glucose Transporter 2
  • Symporters
  • Succinic Acid
  • 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol
  • empagliflozin
  1 Citation (Scopus)

• The effect of regular consumption of lupin-containing foods on glycaemic control and blood pressure in people with type 2 diabetes mellitus

  Ward, N. C., Mori, T. A., Beilin, L. J., Johnson, S., Williams, C., Gan, S. K., Puddey, I. B., Woodman, R., Phillips, M., Connolly, E. & Hodgson, J. M., 29 Jan 2020, In : Food & function. 11, 1, p. 741-747

  Research output: Contribution to journal › Article

  • glycemic control
  • Fortified Food
  • noninsulin-dependent diabetes mellitus
  • Lupinus
  • enriched foods
  1 Citation (Scopus)

• The effects of vitamin K-rich green leafy vegetables on bone metabolism: A 4-week randomised controlled trial in middle-aged and older individuals

  Sim, M., Lewis, J. R., Prince, R. L., Levinger, I., Brennan-Speranza, T. C., Palmer, C., Bondonno, C. P., Bondonno, N. P., Devine, A., Ward, N. C., Byrnes, E., Schultz, C. J., Woodman, R., Croft, K., Hodgson, J. M. & Blekkenhorst, L. C., Jun 2020, In : Bone Reports. 12, 100274.

  Research output: Contribution to journal › Article

  Open Access

  • Vitamin K 1
  • Vitamin K
  • Vegetables
  • Osteocalcin
  • Randomized Controlled Trials
  2 Citations (Scopus)
• 2019

  Clinical guidance on the contemporary use of proprotein convertase subtilisin/kexin type 9 monoclonal antibodies

  Ward, N. C., Page, M. M. & Watts, G. F., 1 Apr 2019, In : Diabetes, Obesity and Metabolism. 21, S1, p. 52-62 11 p.

  Research output: Contribution to journal › Article

  • Proprotein Convertase 9
  • LDL Cholesterol
  • Monoclonal Antibodies
  • Cardiovascular Diseases
  • Ezetimibe

• Enzymatically-Modified Isoquercitrin Improves Endothelial Function in Volunteers at Risk of Cardiovascular Disease

  Bondonno, N. P., Bondonno, C. P., Ward, N. C., Woodman, R. J., Hodgson, J. M. & Croft, K. D., 20 Aug 2019, In : British Journal of Nutrition.

  Research output: Contribution to journal › Article

  Open Access

  File

  • isoquercitrin
  • Volunteers
  • Quercetin
  • Cardiovascular Diseases
  • Blood Pressure
  2 Citations (Scopus)

  540 Downloads (Pure)

• Lipid management in people with peripheral artery disease

  Golledge, J., Ward, N. C. & Watts, G. F., 1 Dec 2019, In : Current Opinion in Lipidology. 30, 6, p. 470-476 7 p.

  Research output: Contribution to journal › Article

  • Peripheral Arterial Disease
  • LDL Cholesterol
  • Lipids
  • Proprotein Convertase 9
  • Myocardial Infarction
  2 Citations (Scopus)

• Molecular, Population, and Clinical Aspects of Lipoprotein(a): A Bridge Too Far?

  Ward, N. C., Kostner, K. M., Sullivan, D. R., Nestel, P. & Watts, G. E., Dec 2019, In : Journal of Clinical Medicine. 8, 12, 23 p., 2073.

  Research output: Contribution to journal › Review article

• PCSK9 inhibition 2018: riding a new wave of coronary prevention

  Ward, N. C., Page, M. M. & Watts, G. F., 31 Jan 2019, In : Clinical Science. 133, 2, p. 205-224 20 p.

  Research output: Contribution to journal › Review article
  7 Citations (Scopus)

• Statin Toxicity

  Ward, N. C., Watts, G. F. & Eckel, R. H., 18 Jan 2019, In : Circulation Research. 124, 2, p. 328-350 23 p.

  Research output: Contribution to journal › Article

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Muscles
  • Primary Prevention
  • Secondary Prevention
  • LDL Cholesterol
  81 Citations (Scopus)

• The gut microbiome and cardiovascular disease: current knowledge and clinical potential

  Ahmad, A. F., Dwivedi, G., O'Gara, F., Caparros-Martin, J. & Ward, N. C., 1 Nov 2019, In : American journal of physiology. Heart and circulatory physiology. 317, 5, p. H923-H938

  Research output: Contribution to journal › Article

  • Gastrointestinal Microbiome
  • Cardiovascular Diseases
  • Atherosclerosis
  • Dysbiosis
  • Human Body
  11 Citations (Scopus)

• The gut microbiome and heart failure

  Ahmad, A. F., Ward, N. C. & Dwivedi, G., 1 Mar 2019, In : Current Opinion in Cardiology. 34, 2, p. 225-232 8 p.

  Research output: Contribution to journal › Article

  • Gastrointestinal Microbiome
  • Heart Failure
  • Cardiovascular Diseases
  • Microbiota
  • Dysbiosis
  3 Citations (Scopus)

• Vegetable nitrate intakes are associated with reduced self-reported cardiovascular-related complications within a representative sample of middle-aged australian women, prospectively followed up for 15 years

  Jackson, J. K., Patterson, A. J., Macdonald-Wicks, L. K., Forder, P. M., Blekkenhorst, L. C., Bondonno, C. P., Hodgson, J. M., Ward, N. C., Holder, C., Oldmeadow, C., Byles, J. E. & McEvoy, M. A., 1 Feb 2019, In : Nutrients. 11, 2, 240.

  Research output: Contribution to journal › Article

  Open Access

  • Nitrates
  • Vegetables
  • nitrates
  • vegetables
  • cardiovascular diseases
  1 Citation (Scopus)

• What's new on therapies for elevated lipoprotein(a)

  Ward, N. C., Schultz, C. J. & Watts, G. F., 3 Jun 2019, In : Expert Review of Clinical Pharmacology. 12, 6, p. 495-499 5 p.

  Research output: Contribution to journal › Editorial
  1 Citation (Scopus)
• 2018

  Cardiovascular health benefits of specific vegetable types: A narrative review

  Blekkenhorst, L. C., Sim, M., Bondonno, C. P., Bondonno, N. P., Ward, N. C., Prince, R. L., Devine, A., Lewis, J. R. & Hodgson, J. M., 11 May 2018, In : Nutrients. 10, 5, 595.

  Research output: Contribution to journal › Review article

  Open Access

  • vegetable consumption
  • Insurance Benefits
  • Vegetables
  • chronic diseases
  • vegetables
  25 Citations (Scopus)

• Dietary nitrate and diet quality: An examination of changing dietary intakes within a representative sample of Australian women

  Jackson, J. K., Patterson, A. J., Macdonald-Wicks, L. K., Bondonno, C. P., Blekkenhorst, L. C., Ward, N. C., Hodgson, J. M., Byles, J. E. & McEvoy, M. A., 1 Aug 2018, In : Nutrients. 10, 8, 1005.

  Research output: Contribution to journal › Article

  Open Access

  • nutritional adequacy
  • Nitrates
  • food intake
  • nitrates
  • Diet
  5 Citations (Scopus)

• Effect of adding milk to black tea on vascular function in healthy men and women: a randomised controlled crossover trial

  Ahmad, A. F., Rich, L., Koch, H., Croft, K. D., Ferruzzi, M. G., Kay, C. D., Hodgson, J. M. & Ward, N. C., 13 Dec 2018, In : Food & function. 9, 12, p. 6307-6314 8 p.

  Research output: Contribution to journal › Article

  • black tea
  • cross-over studies
  • Tea
  • Milk
  • Cross-Over Studies
  5 Citations (Scopus)

• Flavonoid-Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease: A Randomized Controlled Clinical Trial

  Bondonno, N. P., Bondonno, C. P., Blekkenhorst, L. C., Considine, M. J., Maghzal, G., Stocker, R., Woodman, R. J., Ward, N. C., Hodgson, J. M. & Croft, K. D., Feb 2018, In : MOLECULAR NUTRITION & FOOD RESEARCH. 62, 3, 1700674.

  Research output: Contribution to journal › Article

  • randomized clinical trials
  • Malus
  • at-risk population
  • cardiovascular diseases
  • Flavonoids
  26 Citations (Scopus)

• Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet

  Tan, S., Caparros-Martin, J. A., Matthews, V. B., Koch, H., O'Gara, F., Croft, K. D. & Ward, N. C., 1 Dec 2018, In : Scientific Reports. 8, 1, 10100.

  Research output: Contribution to journal › Article

  Open Access

  • isoquercitrin
  • Inulin
  • High Fat Diet
  • Gastrointestinal Microbiome
  • Metabolic Syndrome
  14 Citations (Scopus)

• Long-Term Dietary Nitrate Supplementation Does Not Prevent Development of the Metabolic Syndrome in Mice Fed a High-Fat Diet

  Matthews, V. B., Hollingshead, R., Koch, H., Croft, K. D. & Ward, N. C., 1 Jan 2018, In : International Journal of Endocrinology. 2018, 7969750.

  Research output: Contribution to journal › Article

  Open Access

  • Nitrates
  • Dietary Supplements
  • High Fat Diet
  • Metabolic Syndrome
  • Nitric Oxide
  2 Citations (Scopus)

• Nitrate, the oral microbiome, and cardiovascular health: A systematic literature review of human and animal studies

  Blekkenhorst, L. C., Bondonno, N. P., Liu, A. H., Ward, N. C., Prince, R. L., Lewis, J. R., Devine, A., Croft, K. D., Hodgson, J. M. & Bondonno, C. P., 1 Apr 2018, In : American Journal of Clinical Nutrition. 107, 4, p. 504-522 19 p.

  Research output: Contribution to journal › Article

  • Nitrates
  • Microbiota
  • Systematic Reviews
  • Animals
  • Health
  19 Citations (Scopus)

• Nitrate-rich vegetables do not lower blood pressure in individuals with mildly elevated blood pressure: A 4-wk randomized controlled crossover trial

  Blekkenhorst, L. C., Lewis, J. R., Prince, R. L., Devine, A., Bondonno, N. P., Bondonno, C. P., Wood, L. G., Puddey, I. B., Ward, N. C., Croft, K. D., Woodman, R. J., Beilin, L. J. & Hodgson, J. M., 1 Jun 2018, In : American Journal of Clinical Nutrition. 107, 6, p. 894-908 15 p.

  Research output: Contribution to journal › Article

  Open Access

  • Nitrates
  • Vegetables
  • Cross-Over Studies
  • Randomized Controlled Trials
  • Blood Pressure
  14 Citations (Scopus)

• Nutraceuticals in the management of patients with statin-associated muscle symptoms, with a note on real-world experience

  Ward, N. C., Pang, J., Ryan, J. D. M. & Watts, G. F., 24 Jan 2018, In : Clinical Cardiology. 41, 1, p. 159-165

  Research output: Contribution to journal › Review article

  Open Access

  • Dietary Supplements
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • LDL Cholesterol
  • Muscles
  • Cardiovascular Diseases
  10 Citations (Scopus)

• PCSK9 monoclonal antibody on a knife-edge: An article of faith in FH?

  Ward, N. C. & Watts, G. F., 1 Jul 2018, In : Journal of Clinical Lipidology. 12, 4, p. 844-848 5 p.

  Research output: Contribution to journal › Editorial

• Reply to OM Shannon et al

  Blekkenhorst, L. C., Lewis, J. R., Prince, R. L., Devine, A., Bondonno, N. P., Bondonno, C. P., Wood, L. G., Puddey, I. B., Ward, N. C., Croft, K. D., Woodman, R. J., Beilin, L. J. & Hodgson, J. M., 1 Dec 2018, In : The American Journal of Clinical Nutrition. 108, 6, p. 1353-1354 2 p.

  Research output: Contribution to journal › Letter
  1 Citation (Scopus)

• Screening plant derived dietary phenolic compounds for bioactivity related to cardiovascular disease

  Croft, K. D., Yamashita, Y., O'Donoghue, H., Shirasaya, D., Ward, N. C. & Ashida, H., 1 Apr 2018, In : Fitoterapia. 126, p. 22-28 7 p.

  Research output: Contribution to journal › Article

  • phenolic acid
  • Nitric Oxide Synthase Type III
  • Cardiovascular Diseases
  • Glucose
  • Muscle Cells
  12 Citations (Scopus)

• Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production

  Saunders, B. M., Rudnicka, C., Filipovska, A., Davies, S., Ward, N., Hricova, J., Schlaich, M. P. & Matthews, V. B., 1 Jan 2018, In : Immunology and Cell Biology. 96, 1, p. 41-53 13 p.

  Research output: Contribution to journal › Article

  • Nutrition
  • Interleukin-6
  • Insulin Resistance
  • Obesity
  • Cytokines
  4 Citations (Scopus)

• Vegetable-derived bioactive nitrate and cardiovascular health

  Bondonno, C. P., Blekkenhorst, L. C., Liu, A. H., Bondonno, N. P., Ward, N. C., Croft, K. D. & Hodgson, J. M., 1 Jun 2018, In : Molecular Aspects of Medicine. 61, p. 83-91 9 p.

  Research output: Contribution to journal › Review article

  • Vegetables
  • Nitrates
  • Health
  • Nitric Oxide
  • Nitrites
  21 Citations (Scopus)
• 2017

  Development of a reference database for assessing dietary nitrate in vegetables

  Blekkenhorst, L. C., Prince, R. L., Ward, N. C., Croft, K. D., Lewis, J. R., Devine, A., Shinde, S., Woodman, R. J., Hodgson, J. M. & Bondonno, C. P., Aug 2017, In : Molecular Nutrition and Food Research. 61, 8, 13 p., 1600982.

  Research output: Contribution to journal › Article
  30 Citations (Scopus)

• Dietary inflammatory index in relation to sub-clinical atherosclerosis and atherosclerotic vascular disease mortality in older women

  Bondonno, N. P., Lewis, J. R., Blekkenhorst, L. C., Shivappa, N., Woodman, R. J., Bondonno, C. P., Ward, N. C., Hébert, J. R., Thompson, P. L., Prince, R. L. & Hodgson, J. M., 14 Jun 2017, In : British Journal of Nutrition. 117, 11, p. 1577-1586 10 p.

  Research output: Contribution to journal › Article

  • Vascular Diseases
  • Atherosclerosis
  • Carotid Intima-Media Thickness
  • Common Carotid Artery
  • Mortality
  16 Citations (Scopus)

• Novel protein biomarkers associated with coronary artery disease in statin-treated patients with familial hypercholesterolemia

  Bos, S., Phillips, M., Watts, G. F., Verhoenen, A. J. M., Sijbrands, E. J. G. & Ward, N. C., Jun 2017, In : Journal of Clinical Lipidology. 11, 3, p. 682-693 12 p.

  Research output: Contribution to journal › Article

  • Hyperlipoproteinemia Type II
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Coronary Artery Disease
  • histidine-rich proteins
  • Biomarkers
  9 Citations (Scopus)

• Recent perspectives on the role of nutraceuticals as cholesterol-lowering agents

  Ward, N., Sahebkar, A., Banach, M. & Watts, G., 1 Dec 2017, In : Current Opinion in Lipidology. 28, 6, p. 495-501 7 p.

  Research output: Contribution to journal › Review article

  • Dietary Supplements
  • Cholesterol
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • red yeast rice
  • Phytosterols
  23 Citations (Scopus)

• Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism

  Caparros-Martin, J. A., Lareu, R. R., Ramsay, J. P., Peplies, J., Reen, F. J., Headlam, H. A., Ward, N. C., Croft, K. D., Newsholme, P., Hughes, J. D. & O'Gara, F., 9 Aug 2017, In : Microbiome. 5, 15 p.

  Research output: Contribution to journal › Article

  Open Access
  52 Citations (Scopus)

• Structural requirements of flavonoids to induce heme oxygenase-1 expression

  Croft, K. D., Zhang, D., Jiang, R., Ayer, A., Shengule, S., Payne, R. J., Ward, N. C. & Stocker, R., 1 Dec 2017, In : Free Radical Biology and Medicine. 113, p. 165-175 11 p.

  Research output: Contribution to journal › Article

  • Heme Oxygenase-1
  • Flavonoids
  • Oxidants
  • Endothelial cells
  • quinone
  16 Citations (Scopus)

• The acute effect of coffee on endothelial function and glucose metabolism following a glucose load in healthy human volunteers

  Boon, E. A. J., Croft, K. D., Shinde, S., Hodgson, J. M. & Ward, N. C., 1 Sep 2017, In : Food and Function. 8, 9, p. 3366-3373 8 p.

  Research output: Contribution to journal › Article

  • acute effects
  • Coffee
  • volunteers
  • chlorogenic acid
  • beverages
  9 Citations (Scopus)

• The cardiovascular health benefits of apples: Whole fruit vs. isolated compounds

  Bondonno, N. P., Bondonno, C. P., Ward, N. C., Hodgson, J. M. & Croft, K. D., 1 Nov 2017, In : Trends in Food Science and Technology. 69, B, p. 243-256 14 p.

  Research output: Contribution to journal › Review article

  • Malus
  • Insurance Benefits
  • Polyphenols
  • Fruit
  • apples
  49 Citations (Scopus)

• Vegetable and fruit intake and fracture-related hospitalisations: A prospective study of older women

  Blekkenhorst, L. C., Hodgson, J. M., Lewis, J. R., Devine, A., Woodman, R. J., Lim, W. H., Wong, G., Zhu, K., Bondonno, C. P., Ward, N. C. & Prince, R. L., 18 May 2017, In : Nutrients. 9, 5, 15 p., 511.

  Research output: Contribution to journal › Article

  Open Access

  File

  • prospective studies
  • vegetable consumption
  • fruit consumption
  • Vegetables
  • Fruit
  9 Citations (Scopus)

  296 Downloads (Pure)