Find Research Outputs

Search results

• 2016

  A Transcriptomic Signature of Mouse Liver Progenitor Cells

  Passman, A., Low, J., London, R., Tirnitz-Parker, N., Miyajima, A., Tanaka, M., Strick-Marchand, H., Darlington, G. J., Finch-Edmondson, M., Ochsner, S., Zhu, C., Whelan, J., Callus, B. & Yeoh, G., Aug 2016, In : Stem Cells International. 2016, p. 1-15

  Research output: Contribution to journal › Article

  Open Access

  • Stem Cells
  • Liver
  • Hepatocellular Carcinoma
  • Liver Diseases
  • Liver Regeneration
  2 Citations (Scopus)

• Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins

  Goodall, K. J., Finch-Edmondson, M., van Vuuren, J., Yeoh, G. C., Gentle, I. E., Vince, J. E., Ekert, P. G., Vaux, D. L. & Callus, B. A., 2 Nov 2016, In : PLoS One. 11, 11, p. 1-18

  Research output: Contribution to journal › Article

  Open Access

  • Cycloheximide
  • Myeloid Cells
  • Cell Death
  • Roscovitine
  • Proteins
  3 Citations (Scopus)

• Efficient generation of functional hepatocyte-like cells from mouse liver progenitor cells via indirect co-culture with immortalized human hepatic stellate cells

  Pan, X. P., Wang, Y. N., Yu, X. P., Zhu, C. X., Li, J. Z., Du, W. B., Zhang, Y. M., Cao, H. C., Zhang, Y. H., Zhu, D. H., Yeoh, G. & Li, L. J., 6 Apr 2016, In : Hepatobiliary and Pancreatic Diseases International. 15, 2, p. 173-179 7 p.

  Research output: Contribution to journal › Article

  • Hepatic Stellate Cells
  • Coculture Techniques
  • Hepatocytes
  • Stem Cells
  • Liver
  2 Citations (Scopus)

• Identification of a thalidomide derivative that selectively targets tumorigenic liver progenitor cells and comparing its effects with lenalidomide and sorafenib

  Woo, K., Stewart, S. G., Kong, G. S., Finch-Edmondson, M. L., Dwyer, B. J., Yeung, S. Y., Abraham, L. J., Kampmann, S. S., Diepeveen, L. A., Passman, A. M., Elsegood, C. L., Tirnitz-Parker, J. E. E., Callus, B. A., Olynyk, J. K. & Yeoh, G. C. T., 14 Sep 2016, In : European Journal of Medicinal Chemistry. 120, p. 275-283

  Research output: Contribution to journal › Article

  Open Access

  File

  • Lenalidomide
  • Sorafenib
  • Thalidomide
  • Liver
  • Derivatives
  6 Citations (Scopus)

  649 Downloads (Pure)

• Splice variant insertions in the C-terminus impairs YAP's transactivation domain

  Finch-Edmondson, M. L., Strauss, R. P., Clayton, J. S., Yeoh, G. C. & Callus, B. A., 2016, In : Biochemistry and Biophysics Reports. 6, p. 24-31 8 p.

  Research output: Contribution to journal › Article

  Open Access

  • Transcriptional Activation
  • Protein Isoforms
  • Leucine Zippers
  • WW Domains
  • Human YAP1 (Yes-associated) protein
  13 Citations (Scopus)
• 2018

  A microRNA-7/growth arrest specific 6/TYRO3 axis regulates the growth and invasiveness of sorafenib-resistant cells in human hepatocellular carcinoma

  Kabir, T. D., Ganda, C., Brown, R. M., Beveridge, D. J., Richardson, K. L., Chaturvedi, V., Candy, P., Epis, M., Wintle, L., Kalinowski, F., Kopp, C., Stuart, L. M., Yeoh, G. C., George, J. & Leedman, P. J., 1 Jan 2018, In : Hepatology. 67, 1, p. 216-231 16 p.

  Research output: Contribution to journal › Article

  • Sorafenib
  • MicroRNAs
  • Hepatocellular Carcinoma
  • Growth
  • Proto-Oncogene Proteins c-akt
  57 Citations (Scopus)

• InForm software: A semi-Automated research tool to identify presumptive human hepatic progenitor cells, and other histological features of pathological significance

  Kramer, A. S., Latham, B., Diepeveen, L. A., Mou, L., Laurent, G. J., Elsegood, C., Ochoa-Callejero, L. & Yeoh, G. C., 1 Dec 2018, In : Scientific Reports. 8, 1, 3418.

  Research output: Contribution to journal › Article

  Open Access

  • Pathologists
  • Hepatocytes
  • Software
  • Stem Cells
  • Liver Diseases
  5 Citations (Scopus)

• The Vascularised Chamber as an In Vivo Bioreactor

  Yap, K. K., Yeoh, G. C., Morrison, W. A. & Mitchell, G. M., Oct 2018, In : Trends in Biotechnology. 36, 10, p. 1011-1024

  Research output: Contribution to journal › Article

  • Bioreactors
  • Tissue
  • Biomedical Engineering
  • Tissue Survival
  • Microsurgery
  15 Citations (Scopus)

• Transdifferentiation of pancreatic progenitor cells to hepatocyte-like cells is not serum-dependent when facilitated by extracellular matrix proteins

  Gratte, F. D., Pasic, S., Olynyk, J. K., Yeoh, G. C. T., Tosh, D., Coombe, D. R. & Tirnitz-Parker, J. E. E., 1 Dec 2018, In : Scientific Reports. 8, 1, 4385.

  Research output: Contribution to journal › Article

  Open Access

  • Extracellular Matrix Proteins
  • Hepatocytes
  • Stem Cells
  • Serum
  • Liver
  4 Citations (Scopus)
• 2019

  Human Amnion Epithelial Cell Therapy for Chronic Liver Disease

  Andrewartha, N. & Yeoh, G., 7 Aug 2019, In : Stem Cells International. 2019, 10 p., 8106482.

  Research output: Contribution to journal › Review article

  Open Access
  6 Citations (Scopus)

• Immune-mediated ECM depletion improves tumour perfusion and payload delivery

  Yeow, Y. L., Kotamraju, V. R., Wang, X., Chopra, M., Azme, N., Wu, J., Schoep, T. D., Delaney, D. S., Feindel, K., Li, J., Kennedy, K. M., Allen, W. M., Kennedy, B. F., Larma, I., Sampson, D. D., Mahakian, L. M., Fite, B. Z., Zhang, H., Friman, T., Mann, A. P. & 11 others, Aziz, F. A., Kumarasinghe, M. P., Johansson, M., Ee, H. C., Yeoh, G., Mou, L., Ferrara, K. W., Billiran, H., Ganss, R., Ruoslahti, E. & Hamzah, J., 11 Nov 2019, In : EMBO Molecular Medicine. e10923.

  Research output: Contribution to journal › Article

  Open Access

  • Extracellular Matrix
  • Perfusion
  • Neoplasms
  • Tumor Necrosis Factor-alpha
  • Peptides
  3 Citations (Scopus)

• Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation

  Ferreira, N., Perks, K. L., Rossetti, G., Rudler, D. L., Hughes, L. A., Ermer, J. A., Scott, L. H., Kuznetsova, I., Richman, T. R., Narayana, V. K., Abudulai, L. N., Shearwood, A-M. J., Cserne Szappanos, H., Tull, D., Yeoh, G. C., Hool, L. C., Filipovska, A. & Rackham, O., 16 Dec 2019, In : The EMBO Journal. 38, 24, 19 p., e102155.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Metabolism
  • Mammals
  • Mitochondrial Proteins
  • Nuclear Proteins
  • Cell Proliferation
  7 Citations (Scopus)

  282 Downloads (Pure)
• 2020

  Human Amnion Epithelial Cells Produce Soluble Factors that Enhance Liver Repair by Reducing Fibrosis While Maintaining Regeneration in a Model of Chronic Liver Injury

  Hodge, A., Andrewartha, N., Lourensz, D., Strauss, R., Correia, J., Goonetilleke, M., Yeoh, G., Lim, R. & Sievert, W., 1 Jan 2020, In : Cell Transplantation. 29, p. 963689720950221

  Research output: Contribution to journal › Article

  Open Access

  • Epithelial Cells
  • Amnion
  • Liver
  • Regeneration
  • Repair

• Liver sinusoidal endothelial cells promote the differentiation and survival of mouse vascularised hepatobiliary organoids

  Yap, K. K., Gerrand, Y. W., Dingle, A. M., Yeoh, G. C., Morrison, W. A. & Mitchell, G. M., Aug 2020, In : Biomaterials. 251, 120091.

  Research output: Contribution to journal › Article

  • Endothelial cells
  • Organoids
  • Liver
  • Cell Differentiation
  • Cell Survival

• Loss of ARF/INK4A promotes liver progenitor cell transformation toward tumorigenicity supporting their role in hepatocarcinogenesis

  Strauss, R. P., Audsley, K. M., Passman, A. M., van Vuuren, J. H., Finch-Edmondson, M. L., Callus, B. A. & Yeoh, G. C., 1 Jan 2020, In : Gene Expression The Journal of Liver Research. 20, 1, p. 39-52 14 p.

  Research output: Contribution to journal › Article

  Open Access

  • Cyclin-Dependent Kinase Inhibitor p16
  • Reading Frames
  • Stem Cells
  • Liver
  • Neoplastic Cell Transformation