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• 2011

  Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents

  Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418

  Research output: Contribution to journal › Article
  56 Citations (Scopus)

• Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program

  Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465

  Research output: Contribution to journal › Review article

• Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

  National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.

  Research output: Contribution to journal › Article

  • Genome-Wide Association Study
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Ulcerative Colitis
  • Genes
  513 Citations (Scopus)

• Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention

  Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708

  Research output: Contribution to journal › Article

  Open Access
  9 Citations (Scopus)

• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, Colombel, J-F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J-P., Jobin, G., Laukens, D., Lawrance, I., Lémann, M., Levine, A., Libioulle, C., Louis, E., Mcgovern, D. P., Milla, M., Montgomery, G. W., Morley, K. I., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panés, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L., Seielstad, M., Hillary Steinhart, A., Targan, S. R., Van Den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H-J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S. R., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., 2011, In : Nature Genetics. 43, 3, p. 246-252

  Research output: Contribution to journal › Article
  936 Citations (Scopus)

• Predictors of fibrostenotic Crohn's Disease

  Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007

  Research output: Contribution to journal › Article
  49 Citations (Scopus)

• Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

  Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Haritunians, T., Jostins, L., Latiano, A., Mathew, C. G., Montgomery, G. W., Prescott, N. J., Rotter, J. I., Schumm, P., Sharma, Y., Simms, L. A., Taylor, K. D., Whiteman, D., Wijmenga, C., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Bunning, C., Cohen, A., Colombel, J-F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S. L., Halfvarson, J., Hommes, D., Hugot, J-P., Laukens, D., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D. D., Regueiro, M., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A. H., Stokkers, P. C. F., Torkvist, L., Kullak-Ublick, G., Walters, T., Targan, S. R., Brant, S. R., Rioux, J. D., D'Amato, M., Weersma, R., Kutharthasan, S., Griffiths, A. M., Mansfield, J. C., Vermeire, S., Duerr, R. H., Silverberg, M. S., Satsangi, J., Schreiber, S., Cho, J. H., Annese, V., Hakonarson, H. & Parkes, M., 2011, In : PLoS Genetics. 7, 1, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  351 Citations (Scopus)

• Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study

  Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193

  Research output: Contribution to journal › Article
  99 Citations (Scopus)

• SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer

  Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  47 Citations (Scopus)

• Topical agents for idiopathic distal colitis and proctitis

  Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43

  Research output: Contribution to journal › Article
  19 Citations (Scopus)

• Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD

  Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371

  Research output: Contribution to journal › Article

  8 Citations (Scopus)
• 2012

  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, Achkar, J-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Büning, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Glas, J., Haritunians, T., Hart, A., Hawkey, C., Hedl, M., Hu, X., Karlsen, T. H., Kupcinskas, L., Kugathasan, S., Latiano, A., Laukens, D., Lawrance, I., Lees, C. W., Louis, E., Mahy, G., Mansfield, J., Morgan, A. R., Mowat, C., Newman, W., Palmieri, O., Ponsioen, C. Y., Potocnik, U., Prescott, N. J., Regueiro, M., Rotter, J. I., Russell, R. K., Sanderson, J. D., Sans, M., Satsangi, J., Schreiber, S., Simms, L. A., Sventoraityte, J., Targan, S. R., Taylor, K. D., Tremelling, M., Verspaget, H. W., De Vos, M., Wijmenga, C., Wilson, D. C., Winkelmann, J., Xavier, R. J., Zeissig, S., Zhang, B., Zhang, C. K., Zhao, H., Silverberg, M. S., Annese, V., Hakonarson, H., Brant, S. R., Radford-Smith, G., Mathew, C. G., Rioux, J. D., Schadt, E. E., Daly, M. J., Franke, A., Parkes, M., Vermeire, S., Barrett, J. C. & Cho, J. H., 1 Nov 2012, In : Nature. 491, 7422, p. 119-124

  Research output: Contribution to journal › Article

  • Host Microbial Interactions
  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn Disease
  2700 Citations (Scopus)

• Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study

  Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293

  Research output: Contribution to journal › Article
  13 Citations (Scopus)

• Microbiota and management of inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140

  Research output: Contribution to journal › Review article
  3 Citations (Scopus)

• Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984

  Research output: Contribution to journal › Review article
  5 Citations (Scopus)

• NAFLD, the changing face of IBD

  Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2014

  Detection of liver injury in IBD using transient elastography

  Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677

  Research output: Contribution to journal › Article

  • Elasticity Imaging Techniques
  • Inflammatory Bowel Diseases
  • Liver
  • Wounds and Injuries
  • Inflammatory Bowel Disease 5
  9 Citations (Scopus)

• Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response

  Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.

  Research output: Contribution to journal › Article

  • Crohn Disease
  • Tumor Necrosis Factor-alpha
  • Adrenal Cortex Hormones
  • Physicians
  • Steroids
  1 Citation (Scopus)

• HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

  Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, Fedorak, R. N., Florin, T. H., Gaya, D. R., Greig, E., Halfvarson, J., Hart, A., Irving, P., Jones, G., Karban, A., Lawrance, I., Lee, J. C., Lees, C., Lev-Tzion, R., Lindsay, J. O., Mansfield, J., Mawdsley, J., Mazhar, Z., Parkes, M., Parnell, K., Orchard, T. R., Radford-Smith, G., Russell, R. K., Reffitt, D., Satsangi, J., Silverberg, M. S., Sturniolo, G. C., Tremelling, M., Tsianos, V., Van Heel, D. A., Walsh, A., Watermeyer, G., Weersma, R. K., Zeissig, S., Rossjohn, J., Holden, A. L., International Serious Adverse Events Consortium, I. S. A. E. C., Ibd Pharmacogenetics Study Group, IBD. P. S. G. & Ahmad, T., 2014, In : Nature Genetics. 46, 10, p. 1131-1136

  Research output: Contribution to journal › Article
  109 Citations (Scopus)

• Mechanisms of initiation and progression of intestinal fibrosis in IBD

  Latella, G., Di Gregorio, J., Flati, V., Rieder, F. & Lawrance, I., 2014, In : Scandinavian Journal of Gastroenterology. 50, p. 53-65

  Research output: Contribution to journal › Review article
  80 Citations (Scopus)

• PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease

  Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• Preventing infective complications in inflammatory bowel disease

  Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698

  Research output: Contribution to journal › Review article

  Open Access

  • Inflammatory Bowel Diseases
  • Opportunistic Infections
  • Physicians
  • Biological Factors
  • Patient Education
  9 Citations (Scopus)

• Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function

  Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study

  Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606

  Research output: Contribution to journal › Article

  • Patient Acceptance of Health Care
  • Ulcerative Colitis
  • Health Care Costs
  • Observational Studies
  • Cross-Sectional Studies
  68 Citations (Scopus)

• Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD

  Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165

  Research output: Contribution to journal › Review article

  • Colitis
  • Inflammatory Bowel Diseases
  • Fibrosis
  • Education
  • Tissue Inhibitor of Metalloproteinases
  98 Citations (Scopus)

• The importance of validating proposed genetic profiles in IBD

  Lawrance, I., May 2014, In : Journal of Internal Medicine.

  Research output: Contribution to journal › Review article

• The role of vitamin D in gastrointestinal inflammation

  Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923

  Research output: Contribution to journal › Review article

  • Vitamin D
  • Inflammation
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Adaptive Immunity
  26 Citations (Scopus)

• What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

  Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258

  Research output: Contribution to journal › Article

  Open Access

  • Inflammatory Bowel Diseases
  • Tumor Necrosis Factor-alpha
  • Mercaptopurine
  • Physicians
  • Mycophenolic Acid
  9 Citations (Scopus)
• 2016

  Acute severe ulcerative colitis: Changing treatment paradigms

  Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16

  Research output: Contribution to journal › Article

• Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements

  Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.

  Research output: Contribution to journal › Editorial

  Open Access
  38 Citations (Scopus)

• A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

  Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

  Research output: Contribution to journal › Article

  Open Access
  7 Citations (Scopus)

• Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

  International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.

  Research output: Contribution to journal › Article

  • Sclerosing Cholangitis
  • Comorbidity
  • Chronic Disease
  • Inflammatory Bowel Diseases
  • Molecular Pathology
  276 Citations (Scopus)

• Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease

  Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, Dunckley, P., Gaya, D. R., Gearry, R., Gore, S., Halfvarson, J., Hart, A., Hawkey, C. J., Hoentjen, F., Iqbal, T., Irving, P., Lal, S., Lawrence, I., Lees, C. W., Lewis, S., Lockett, M., Mann, S., Mansfield, J., Mowat, C., Muller, F., Murray, C., Orchard, T., Parkes, M., Phillips, R., Pollok, R., Radford-Smith, G., Sebastian, S., Sen, S., Shirazi, T., Silverberg, M., Solomon, L., Sturniolo, G. C., Thomas, M., Tremelling, M., Tsianos, E. V., Watts, D., Weaver, S., Wesley, E., Holden, A., D'Souza, R., Mulgrew, C. J., Oram, R., Weersma, R. K. & Ahmad, T., 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.

  Research output: Contribution to journal › Article

  • Mesalamine
  • Inflammatory Bowel Diseases
  • Kidney
  • Genome-Wide Association Study
  • Pharmaceutical Preparations
  42 Citations (Scopus)

• Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection

  Julsgaard, M., Christensen, L. A., Gibson, P. R., Gearry, R. B., Fallingborg, J., Hvas, C. L., Bibby, B. M., Uldbjerg, N., Connell, W. R., Rosella, O., Grosen, A., Brown, S. J., Kjeldsen, J., Wildt, S., Svenningsen, L., Sparrow, M. P., Walsh, A., Connor, S. J., Radford-Smith, G., Lawrance, I. & 3 others, Andrews, J. M., Ellard, K. & Bell, S. J., 2016, In : Gastroenterology. 151, 1, p. 110-119

  Research output: Contribution to journal › Article

  • Adalimumab
  • Infliximab
  • Newborn Infant
  • Necrosis
  • Umbilical Cord
  145 Citations (Scopus)

• Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study

  Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ulcerative Colitis
  • Innate Immunity
  • Tumor Necrosis Factor-alpha
  • Toll-Like Receptors
  • Cytokines
  11 Citations (Scopus)

• High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease

  Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C., Oct 2016, In : Inflammatory Bowel Diseases. 22, 10, p. 2456-2464 9 p.

  Research output: Contribution to journal › Article

  • Vitamin D-Binding Protein
  • Crohn Disease
  • Albumins
  • Sunlight
  • Recurrence
  13 Citations (Scopus)

• Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection

  Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, Lawrance, I., Radford-Smith, G., Sloss, A., Sorrentino, D., Gassner, S., Haas, T., Reicht, G., Reinisch, W., Strasser, M., Vogelsang, H., Bossuyt, P., Dewit, O., D'Haens, G., Franchimont, D., Louis, E., Vermeire, S., Bernstein, C. N., Bourdages, R., Chiba, N., Dhalla, S. S., Feagan, B. G., Fedorak, R. N., Lachance, J. R., Panaccione, R., Ropeleski, M., Singh Salh, B., Lukas, M., Colombel, J. F., Allez, M., Desreumaux, P., Dupas, J. L., Grimaud, J. C., Hebuterne, X., Laharie, D., Lerebours, E., Peyrin-Biroulet, L., Reimund, J. M., Viennot, S., Zerbib, F., Antoni, C., Atreya, R., Baumgart, D. C., Berg, C., Boecker, U., Bramkamp, G., Bünning, C., Ehehalt, R., Howaldt, S., Kucharzik, T., Lamprecht, H. G., Mudter, J., Preiss, J. C., Schreiber, S., Seidler, U., Altorjay, I., Banai, J., Lakatos, P. L., Varga, M., Vincze, A., Avni-Biron, I., Fishman, S., Fraser, G. M., Goldin, E., Rachmilewitz, D., Annese, V., Ardizzone, S., Biancone, L., Bossa, F., Danese, S., Fries, W., Gionchetti, P., Maconi, G., Terrosu, G., Usai, P., D'Haens, G. R., Gearry, R. B., Hill, J., Rowbotham, D. S., Schultz, M., Stubbs, R. S., Wallace, D., Walmsley, R. S., Wyeth, J., Malecka-Panas, E., Paradowski, L., Regula, J., Beales, I. P., Campbell, S., Hawthorne, A. B., Parkes, M., Travis, S. P., Achkar, J. P., Behm, B. W., Bickston, S. J., Brown, K. J., Chiorean, M. V., Devilliers, W. J. S., Elliott, D. E., Grunkmeier, D., Hamilton, J. W., Hanauer, S. B., Hanson, J. S., Hardi, R., Helper, D. J., Herfarth, H., Higgins, P. D. R., Holderman, W. H., Kottoor, R., Kreines, M. D., Leman, B. I., Li, X., Loftus, E. V., Noar, M., Oikonomou, I., Onken, J., Peterson, K. A., Phillips, R. P., Randall, C. W., Ricci, M., Ritter, T., Rubin, D. T., Safdi, M., Sandborn, W. J., Sauberman, L., Scherl, E., Schwarz, R. P., Sedghi, S., Shafran, I., Sninsky, C. A., Stein, I., Swoger, J., Vecchio, J., Weinberg, D. I., Wruble, L. D., Yajnik, V. & Younes, Z., 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.

  Research output: Contribution to journal › Article

  Open Access

  • Infliximab
  • Crohn Disease
  • Recurrence
  • Placebos
  • Numbers Needed To Treat
  118 Citations (Scopus)

• Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: A genetic association study

  Cleynen, I., Boucher, G., Jostins, L., Schumm, L. P., Zeissig, S., Ahmad, T., Andersen, V., Andrews, J. M., Annese, V., Brand, S., Brant, S. R., Cho, J. H., Daly, M. J., Dubinsky, M., Duerr, R. H., Ferguson, L. R., Franke, A., Gearry, R. B., Goyette, P., Hakonarson, H. & 22 others, Halfvarson, J., Hov, J. R., Huang, H., Kennedy, N. A., Kupcinskas, L., Lawrance, I., Lee, J. C., Satsangi, J., Schreiber, S., Théâtre, E., Van Der Meulen-De Jong, A. E., Weersma, R. K., Wilson, D. C., Parkes, M., Vermeire, S., Rioux, J. D., Mansfield, J., Silverberg, M. S., Radford-Smith, G., Mcgovern, D. P. B., Barrett, J. C. & Lees, C. W., 9 Jan 2016, In : The Lancet. 387, 10014, p. 156-167 12 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Genetic Association Studies
  • Ulcerative Colitis
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Phenotype
  338 Citations (Scopus)

  458 Downloads (Pure)

• The multidisciplinary team

  Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 17

  Research output: Contribution to journal › Article
  2 Citations (Scopus)
• 2017

  A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis

  Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., Feb 2017.

  Research output: Contribution to conference › Conference presentation/ephemera

• Cellular and Molecular Mediators of Intestinal Fibrosis

  Lawrance, I., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J., Pellino, G., Reif, S., Speca, S. & Latella, G., Dec 2017, In : Journal of Crohn's and Colitis. 11, 12, p. 1491–1503 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Fibrosis
  • Inflammatory Bowel Diseases
  • Inflammation
  • Anti-Inflammatory Agents
  53 Citations (Scopus)

• Dysplasia and colorectal cancer surveillance in inflammatory bowel disease

  Pulusu, S. S. R. & Lawrance, I. C., 3 Aug 2017, In : Expert Review of Gastroenterology and Hepatology. 11, 8, p. 711-722 12 p.

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Colorectal Neoplasms
  • Mesalamine
  • Needs Assessment
  • Chemoprevention
  9 Citations (Scopus)

• Efficacy of rectal tacrolimus for induction therapy in patients with resistant ulcerative proctitis

  Lawrance, I. C., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 1 Aug 2017, In : Clinical Gastroenterology and Hepatology. 15, 8, p. 1248-1255 8 p.

  Research output: Contribution to journal › Article

  • Proctitis
  • Tacrolimus
  • Placebos
  • Therapeutics
  • Ulcerative Colitis
  27 Citations (Scopus)

• Emu oil improves clinical indicators of disease in a mouse model of colitis-associated colorectal cancer

  Chartier, L. C., Howarth, G. S., Lawrance, I. C., Trinder, D., Barker, S. J. & Mashtoub, S., Aug 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, p. 56-56 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Emu Oil Reduces Colonic Damage Severity in a Mouse Model of Chronic Ulcerative Colitis

  Safaeian, R., Howarth, G. S., Lawrance, I. C., Trinder, D. & Mashtoub, S., Apr 2017, In : FASEB Journal. 31, 1 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract

• Fine-mapping inflammatory bowel disease loci to single-variant resolution

  Huang, H., Fang, M., Jostins, L., Umićević Mirkov, M., Boucher, G., Anderson, C. A., Andersen, V., Cleynen, I., Cortes, A., Crins, F., D'Amato, M., Deffontaine, V., Dmitrieva, J., Docampo, E., Elansary, M., Farh, K. K-H., Franke, A., Gori, A-S., Goyette, P., Halfvarson, J. & 27 others, Haritunians, T., Knight, J., Lawrance, I. C., Lees, C. W., Louis, E., Mariman, R., Meuwissen, T., Mni, M., Momozawa, Y., Parkes, M., Spain, S. L., Théâtre, E., Trynka, G., Satsangi, J., van Sommeren, S., Vermeire, S., Xavier, R. J., Weersma, R. K., Duerr, R. H., Mathew, C. G., Rioux, J. D., McGovern, D. P. B., Cho, J. H., Georges, M., Daly, M. J., Barrett, J. C. & International Inflammatory Bowel Disease Genetics Consortium, 13 Jul 2017, In : Nature. 547, 7662, p. 173-178 6 p.

  Research output: Contribution to journal › Article

  Open Access

  File

  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn Disease
  • Epigenomics
  188 Citations (Scopus)

  432 Downloads (Pure)

• Infliximab vs. adalimumab in Crohn's disease: results from 327 patients in an Australian and New Zealand observational cohort study

  the Australian and New Zealand Inflammatory Bowel Disease Consortium, 1 Feb 2017, In : Alimentary Pharmacology and Therapeutics. 45, 4, p. 542-552 11 p.

  Research output: Contribution to journal › Article

  • Adalimumab
  • Infliximab
  • New Zealand
  • Crohn Disease
  • Observational Studies
  23 Citations (Scopus)

• OP007 A multi-centre double blind randomised placebo-controlled study of the use of rectal tacrolimus in the treatment of resistant ulcerative proctitis

  Lawrance, I., Baird, A., Lightowler, D., Radford-Smith, G., Andrews, J. M. & Connor, S., 26 Jan 2017, In : JOURNAL OF CROHNS & COLITIS. 11, 1

  Research output: Contribution to journal › Abstract/Meeting Abstract

  Open Access

• Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

  Chen, G. B., Lee, S. H., Montgomery, G. W., Wray, N. R., Visscher, P. M., Gearry, R. B., Lawrance, I. C., Andrews, J. M., Bampton, P., Mahy, G., Bell, S., Walsh, A., Connor, S., Sparrow, M., Bowdler, L. M., Simms, L. A., Krishnaprasad, K., Radford-Smith, G. L. & Moser, G., 29 Aug 2017, In : BMC Medical Genetics. 18, 1, 94.

  Research output: Contribution to journal › Article

  Open Access

  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Crohn Disease
  • Ulcerative Colitis
  10 Citations (Scopus)

• Serologic antibodies in relation to outcome in postoperative Crohn's disease

  Hamilton, A. L., Kamm, M. A., De Cruz, P., Wright, E. K., Selvaraj, F., Princen, F., Gorelik, A., Liew, D., Lawrance, I. C., Andrews, J. M., Bampton, P. A., Sparrow, M. P., Florin, T. H., Gibson, P. R., Debinski, H., Gearry, R. B., Macrae, F. A., Leong, R. W., Kronborg, I., Radford-Smith, G. & 4 others, Selby, W., Bell, S. J., Brown, S. J. & Connell, W. R., 1 Jun 2017, In : Journal of Gastroenterology and Hepatology (Australia). 32, 6, p. 1195-1203 9 p.

  Research output: Contribution to journal › Article

  • Crohn Disease
  • Recurrence
  • Antibodies
  • Anti-Idiotypic Antibodies
  • Bacterial Antibodies
  11 Citations (Scopus)