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• 2011

  Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents

  Lawrance, I., Willert, R. P. & Murray, K., 2011, In : Endoscopy. 43, 5, p. 412-418

  Research output: Contribution to journal › Article
  56 Citations (Scopus)

• Certolizumab pegol in the treatment of Crohn's disease: evidence from the PRECiSE clinical trial program

  Lawrance, I., 2011, In : CLINICAL INVESTIGATION. 1, 3, p. 459-465

  Research output: Contribution to journal › Review article

• Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

  National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium, United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I., Nov 2011, In : Nature Genetics. 43, 11, p. 1066-1073 8 p.

  Research output: Contribution to journal › Article

  • Genome-Wide Association Study
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Ulcerative Colitis
  • Genes
  505 Citations (Scopus)

• Mesenchymal cell proliferation and programmed cell death: key players in fibrogenesis and new targets for therapeutic intervention

  Luna, J., Masamunt, M. C., Lawrance, I. & Sans, M., 2011, In : American Journal of Physiology-Gastrointestinal and Liver Physiology. 300, p. G703-G708

  Research output: Contribution to journal › Article

  Open Access
  9 Citations (Scopus)

• Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

  Anderson, C. A., Boucher, G., Lees, C. W., Franke, A., D’amato, M., Taylor, K. D., Lee, J. C., Goyette, P., Imielinski, M., Latiano, A., Lagacé, C., Scott, R., Amininejad, L., Bumpstead, S., Baidoo, L., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Büning, C. & 93 others, Colombel, J-F., Denson, L. A., De Vos, M., Dubinsky, M., Edwards, C., Ellinghaus, D., Fehrmann, R. S. N., Floyd, J. A. B., Florin, T., Franchimont, D., Franke, L., Georges, M., Glas, J., Glazer, N. L., Guthery, S. L., Haritunians, T., Hayward, N. K., Hugot, J-P., Jobin, G., Laukens, D., Lawrance, I., Lémann, M., Levine, A., Libioulle, C., Louis, E., Mcgovern, D. P., Milla, M., Montgomery, G. W., Morley, K. I., Mowat, C., Ng, A., Newman, W., Ophoff, R. A., Papi, L., Palmieri, O., Peyrin-Biroulet, L., Panés, J., Phillips, A., Prescott, N. J., Proctor, D. D., Roberts, R., Russell, R., Rutgeerts, P., Sanderson, J., Sans, M., Schumm, P., Seibold, F., Sharma, Y., Simms, L., Seielstad, M., Hillary Steinhart, A., Targan, S. R., Van Den Berg, L. H., Vatn, M., Verspaget, H., Walters, T., Wijmenga, C., Wilson, D. C., Westra, H-J., Xavier, R. J., Zhao, Z. Z., Ponsioen, C. Y., Andersen, V., Torkvist, L., Gazouli, M., Anagnou, N. P., Karlsen, T. H., Kupcinskas, L., Sventoraityte, J., Mansfield, J. C., Kugathasan, S., Silverberg, M. S., Halfvarson, J., Rotter, J. I., Mathew, C. G., Griffiths, A. M., Gearry, R., Ahmad, T., Brant, S. R., Chamaillard, M., Satsangi, J., Cho, J. H., Schreiber, S., Daly, M. J., Barrett, J. C., Parkes, M., Annese, V., Hakonarson, H., Radford-Smith, G., Duerr, R. H., Vermeire, S., Weersma, R. K. & Rioux, J. D., 2011, In : Nature Genetics. 43, 3, p. 246-252

  Research output: Contribution to journal › Article
  932 Citations (Scopus)

• Predictors of fibrostenotic Crohn's Disease

  Rieder, F., Lawrance, I., Leite, A. & Sans, M., 2011, In : Inflammatory Bowel Diseases. 17, 9, p. 2000-2007

  Research output: Contribution to journal › Article
  48 Citations (Scopus)

• Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

  Rossin, E. J., Lage, K., Raychaudhuri, S., Xavier, R. J., Tatar, D., Benita, Y., Lawrance, I., Cotsapas, C., Daly, M. J., Franke, A., Mcgovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., Anderson, C. A. & 78 others, Bis, J. C., Bumpstead, S., Ellinghaus, D., Festen, E. M., Georges, M., Haritunians, T., Jostins, L., Latiano, A., Mathew, C. G., Montgomery, G. W., Prescott, N. J., Rotter, J. I., Schumm, P., Sharma, Y., Simms, L. A., Taylor, K. D., Whiteman, D., Wijmenga, C., Baldassano, R. N., Barclay, M., Bayless, T. M., Brand, S., Bunning, C., Cohen, A., Colombel, J-F., Cottone, M., Stronati, L., Denson, T., De Vos, M., D'Inca, R., Dubinsky, M., Edwards, C., Florin, T., Franchimont, D., Gearry, R., Glas, J., Van Gossum, A., Guthery, S. L., Halfvarson, J., Hommes, D., Hugot, J-P., Laukens, D., Lemann, M., Levine, A., Libioulle, C., Louis, E., Mowat, C., Newman, W., Panes, J., Phillips, A., Proctor, D. D., Regueiro, M., Rutgeerts, P., Sanderson, J., Sans, M., Seibold, F., Steinhart, A. H., Stokkers, P. C. F., Torkvist, L., Kullak-Ublick, G., Walters, T., Targan, S. R., Brant, S. R., Rioux, J. D., D'Amato, M., Weersma, R., Kutharthasan, S., Griffiths, A. M., Mansfield, J. C., Vermeire, S., Duerr, R. H., Silverberg, M. S., Satsangi, J., Schreiber, S., Cho, J. H., Annese, V., Hakonarson, H. & Parkes, M., 2011, In : PLoS Genetics. 7, 1, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  349 Citations (Scopus)

• Randomised clinical trial: certolizumab pegol for fistulas in Crohn's disease - subgroup results from a placebo-controlled study

  Schreiber, S., Lawrance, I., Thomsen, O. Ø., Hanauer, S. B., Bloomfield, R. & Sandborn, W. J., 2011, In : Alimentary pharmacology & therapeutics. 33, p. 185-193

  Research output: Contribution to journal › Article
  99 Citations (Scopus)

• SPARC, FOXP3, CD8 and CD45 Correlation with Disease Recurrence and Long-Term Disease-Free Survival in Colorectal Cancer

  Chew, A., Salama, P., Robbshaw, A., Klopcic, B., Zeps, N., Platell, C. & Lawrance, I., 2011, In : PLoS One. 6, 7, p. 13pp

  Research output: Contribution to journal › Article

  Open Access
  45 Citations (Scopus)

• Topical agents for idiopathic distal colitis and proctitis

  Lawrance, I., 2011, In : Journal of Gastroenterology and Hepatology. 26, 1, p. 36-43

  Research output: Contribution to journal › Article
  19 Citations (Scopus)

• Understanding the Use of Immunosuppressive Agents in the Clinical Management of IBD

  Waters, O. R. & Lawrance, I., 2011, In : Current Drug Targets. 12, 9, p. 1364-1371

  Research output: Contribution to journal › Article

  8 Citations (Scopus)
• 2012

  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., Mcgovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., Anderson, C. A., Essers, J., Mitrovic, M., Ning, K., Cleynen, I., Theatre, E., Spain, S. L., Raychaudhuri, S., Goyette, P., Wei, Z., Abraham, C. & 86 others, Achkar, J-P., Ahmad, T., Amininejad, L., Ananthakrishnan, A. N., Andersen, V., Andrews, J. M., Baidoo, L., Balschun, T., Bampton, P. A., Bitton, A., Boucher, G., Brand, S., Büning, C., Cohain, A., Cichon, S., D'Amato, M., De Jong, D., Devaney, K. L., Dubinsky, M., Edwards, C., Ellinghaus, D., Ferguson, L. R., Franchimont, D., Fransen, K., Gearry, R., Georges, M., Gieger, C., Glas, J., Haritunians, T., Hart, A., Hawkey, C., Hedl, M., Hu, X., Karlsen, T. H., Kupcinskas, L., Kugathasan, S., Latiano, A., Laukens, D., Lawrance, I., Lees, C. W., Louis, E., Mahy, G., Mansfield, J., Morgan, A. R., Mowat, C., Newman, W., Palmieri, O., Ponsioen, C. Y., Potocnik, U., Prescott, N. J., Regueiro, M., Rotter, J. I., Russell, R. K., Sanderson, J. D., Sans, M., Satsangi, J., Schreiber, S., Simms, L. A., Sventoraityte, J., Targan, S. R., Taylor, K. D., Tremelling, M., Verspaget, H. W., De Vos, M., Wijmenga, C., Wilson, D. C., Winkelmann, J., Xavier, R. J., Zeissig, S., Zhang, B., Zhang, C. K., Zhao, H., Silverberg, M. S., Annese, V., Hakonarson, H., Brant, S. R., Radford-Smith, G., Mathew, C. G., Rioux, J. D., Schadt, E. E., Daly, M. J., Franke, A., Parkes, M., Vermeire, S., Barrett, J. C. & Cho, J. H., 1 Nov 2012, In : Nature. 491, 7422, p. 119-124

  Research output: Contribution to journal › Article

  • Host Microbial Interactions
  • Inflammatory Bowel Diseases
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn Disease
  2643 Citations (Scopus)

• Inter-observer agreement for Crohn's disease subphenotypes using the Montreal Classification: How good are we? A multi-centre Australasian study

  Krishnaprasad, K., Andrews, J. M., Lawrance, I., Florin, T., Gearry, R. B., Leong, R. W. L., Mahy, G., Bampton, P., Prosser, R., Leach, P., Chitti, L., Cock, C., Grafton, R., Croft, A. R., Cooke, S., Doecke, J. D. & Radford-Smith, G. L., 2012, In : JOURNAL OF CROHNS & COLITIS. 6, p. 287-293

  Research output: Contribution to journal › Article
  13 Citations (Scopus)

• Microbiota and management of inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Journal of Gastroenterology and Hepatology. 27, 7, p. 1137-1140

  Research output: Contribution to journal › Review article
  3 Citations (Scopus)

• Modifying T-cell trafficking to the intestinal as a potential management for inflammatory bowel disease

  Lawrance, I., Jul 2012, In : Expert Opinion on Investigational Drugs. 21, 7, p. 975-984

  Research output: Contribution to journal › Review article
  5 Citations (Scopus)

• NAFLD, the changing face of IBD

  Thin, L., Kava, J., Lawrance, I. & Olynyk, J., Oct 2012, In : Journal of Gastroenterology and Hepatology (Australia). 27, S4, p. 2 120 p.

  Research output: Contribution to journal › Abstract/Meeting Abstract
• 2013

  A Validated Bowel-Preparation Tolerability Questionnaire and Assessment of Three Commonly Used Bowel-Cleansing Agents

  Lawrance, I., Willert, R. P. & Murray, K., 2013, In : Digestive Diseases and Sciences. 58, 4, p. 926-935

  Research output: Contribution to journal › Article
  11 Citations (Scopus)

• Crohn's disease and smoking: Is it ever too late to quit?

  Lawrance, I., Murray, K., Batman, B., Gearry, R. B., Grafton, R., Krishnaprasad, K., Andrews, J. M., Prosser, R., Bampton, P. A., Cooke, S. E., Mahy, G., Radford-Smith, G., Croft, A. & Hanigan, K., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, 12, p. e665-e671

  Research output: Contribution to journal › Article
  30 Citations (Scopus)

• Deep Resequencing of GWAS Loci Identifies Rare Variants in CARD9, IL23R and RNF186 That Are Associated with Ulcerative Colitis

  Beaudoin, M., Goyette, P., Boucher, G., Lo, K., Rivas, M. A., Stevens, C. R., Alikashani, A., Ladouceur, M. G., Ellinghaus, D., Törkvist, L., Goel, G., Lagacé, C., Annese, V., Bitton, A., Begun, J., Brant, S. R., Bresso, F., Cho, J., Duerr, R. H., Halfvarson, J. & 97 others, Mcgovern, D. P. B., Radford-Smith, G. L., Schreiber, S., Schumm, P. L., Sharma, Y., Silverberg, M. S., Weersma, R. K., D'Amato, M., Vermeire, S., Franke, A., Lettre, G., Xavier, R. J., Daly, M. J., Rioux, J. D., Aumais, G., Bernard, E. J., Cohen, A. Y., Deslandres, C., Lahaie, R. G., Paré, P., Cho, J. H., Targan, S. R., Schumm, P. P., Rutgeerts, P. J., Vermeire, S. A. F. A., Steinhart, A. H., Ahmad, T., Anderson, C. A., Baldassano, R. N., Balschun, T., Barclay, M. L., Barrett, J. C., Bayless, T. M., Bis, J. C. M., Brand, S., Bumpstead, S., Büning, C., Cohen, A., Colombel -, J. F., Cottone, M., D'Incà, R., Denson, T., Dubinsky, M. C., Edwards, C. M., Florin, T. H. J., Franchimont, D. P., Gearry, R. B., Georges, M. A. J. A. J., Glas, J., Van Gossum, A., Griffiths, A. M., Guthery, S. L., Hákonarson, H. H., Haritunians, T., Hugot, J. P., De Jong, D. J., Jostins, L., Kugathasan, S., Kullak- Ublick, G. A., Latiano, A., Laukens, D., Lawrance, I., Lee, J., Lees, C. W., Lémann, M., Levine, A. D., Libioulle, C., Louis, É. J., Mansfield, J. C., Mathew, C. G. P., Mitrovič, M., Montgomery, G. W., Mowat, C. E., Newman, W. G., Palmieri, O., Panés, J., Parkes, M., Phillips, A. M., Ponsioen, C. Y. J., Potočnik, U., Prescott, N. J., Proctor, D. D., Regueiro, M. D., Roberts, R. L., Rotter, J. I., Sanderson, J. D., Sans, M., Satsangi, J., Seibold, F., Simms, L. A., Taylor, K. D., Verspaget, H. W., De Vos, M. P., Walters, T. D., Wang, K., Whiteman, D. C. & Wijmenga, C., 2013, In : PLoS Genetics. 9, 9, p. 11 pp.

  Research output: Contribution to journal › Article

  Open Access

  • colitis
  • Genome-Wide Association Study
  • Ulcerative Colitis
  • Crohn disease
  • loci
  114 Citations (Scopus)

• Dietary Iron Enhances Colonic Inflammation and IL-6/IL-11-Stat3 Signalling Promoting Colonic Tumor Development in Mice

  Chua, A., Klopcic, B., Ho, D., Fu, S., Forrest, C., Croft, K., Olynyk, J., Lawrance, I. & Trinder, D., 2013, In : PLoS One. 8, 11, p. 12pp

  Research output: Contribution to journal › Article

  Open Access
  39 Citations (Scopus)

• European evidence based consensus for endoscopy in inflammatory bowel disease

  ECCO & Lawrance, I., 15 Dec 2013, In : Journal of Crohn's and Colitis. 7, 12, p. 982-1018 37 p.

  Research output: Contribution to journal › Article

  Open Access
  439 Citations (Scopus)

• Genetic susceptibility in IBD: Overlap between ulcerative Colitis and Crohn's disease

  Doecke, J. D., Simms, L. A., Zhao, Z., Huang, N., Hanigan, K., Krishnaprasad, K., Roberts, R. L., Andrews, J. M., Mahy, G., Bampton, P. A., Lewindon, P. J., Florin, T. H. J., Lawrance, I., Gearry, R. B., Montgomery, G. W. & Radford-Smith, G. L., 2013, In : Inflammatory Bowel Diseases. 19, 2, p. 240-245

  Research output: Contribution to journal › Article

  • Genetic Predisposition to Disease
  • Ulcerative Colitis
  • Crohn Disease
  • Single Nucleotide Polymorphism
  • Population Control
  27 Citations (Scopus)

• Implementing guidelines on the prevention of opportunistic infections in inflammatory bowel disease

  Walsh, A. J., Weltman, M., Burger, D., Vivekanandarajah, S., Connor, S., Howlett, M., Radford-Smith, G., Selby, W., Veillard, A. S., Grimm, M. C., Travis, S. P. L. & Lawrance, I., 2013, In : JOURNAL OF CROHNS & COLITIS. 7, p. e449-e456

  Research output: Contribution to journal › Article
  31 Citations (Scopus)

• Large sample size, wide variant spectrum, and advanced machine-learning technique boost risk prediction for inflammatory bowel disease

  International Inflammatory Bowel Disease Genetics Consortium & Lawrance, I. C., 6 Jun 2013, In : American Journal of Human Genetics. 92, 6, p. 1008-1012 5 p.

  Research output: Contribution to journal › Article

  Open Access

  • Machine Learning
  • Ulcerative Colitis
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Sample Size
  88 Citations (Scopus)

• Oral tacrolimus for the treatment of refractory inflammatory bowel disease in the biologic era

  Thin, L. W. Y., Murray, K. & Lawrance, I., 2013, In : Inflammatory Bowel Diseases. 19, 7, p. 1490-1498

  Research output: Contribution to journal › Article

  • Tacrolimus
  • Inflammatory Bowel Diseases
  • Crohn Disease
  • Necrosis
  • Therapeutics
  21 Citations (Scopus)

• Prevention of cancer in IBD - A balancing act

  Mill, J. & Lawrance, I., 2013, In : Minerva Gastroenterologica e Dietologica. 59, 3, p. 261-272

  Research output: Contribution to journal › Review article

  • Inflammatory Bowel Diseases
  • Inflammation
  • Immunosuppression
  • Lymphoma
  • Colorectal Neoplasms
  7 Citations (Scopus)

• Prevention of cancer in IBD – a balancing act

  Lawrance, I., Sep 2013, In : Minerva Gastroenterologica e Dietologica.

  Research output: Contribution to journal › Review article

• Secreted Protein Acidic and Rich in Cysteine (SPARC) Exacerbates Colonic Inflammatory Symptoms in Dextran Sodium Sulphate-Induced Murine Colitis

  Ng, Y. L., Klopcic, B., Lloyd, F., Forrest, C., Greene, W. & Lawrance, I., 2013, In : PLoS One. 8, 10, p. 8pp

  Research output: Contribution to journal › Article

  Open Access
  16 Citations (Scopus)

• Vedolizumab as induction and maintenance therapy for Crohn's disease

  GEMINI 2 Study Group & Lawrance, I., 2013, In : New England Journal of Medicine. 369, 8, p. 711-721 11 p.

  Research output: Contribution to journal › Article

  • vedolizumab
  • Crohn Disease
  • Placebos
  • Therapeutics
  • Nasopharyngitis
  1048 Citations (Scopus)
• 2014

  Detection of liver injury in IBD using transient elastography

  Thin, L. W. Y., Lawrance, I., Spilsbury, K., Kava, J. & Olynyk, J. K., 2014, In : JOURNAL OF CROHNS & COLITIS. 8, 7, p. 671-677

  Research output: Contribution to journal › Article

  • Elasticity Imaging Techniques
  • Inflammatory Bowel Diseases
  • Liver
  • Wounds and Injuries
  • Inflammatory Bowel Disease 5
  9 Citations (Scopus)

• Dose tailoring of anti-tumour necrosis factor-alpha therapy delivers useful clinical efficacy in Crohn disease patients experiencing loss of response

  Ghaly, S., Costello, S., Beswick, L., Pudipeddi, A., Agarwal, A., Sechi, A., Antoniades, S., Headon, B., Connor, S., Lawrance, I., Sparrow, M., Walsh, A. & Andrews, J., 2014, In : Internal Medicine Journal. 45, 2, p. 170-177 8 p.

  Research output: Contribution to journal › Article

  • Crohn Disease
  • Tumor Necrosis Factor-alpha
  • Adrenal Cortex Hormones
  • Physicians
  • Steroids
  1 Citation (Scopus)

• HLA-DQA1–HLA-DRB1variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants

  Heap, G. A., Weedon, M. N., Bewshea, C., Singh, A., Chen, M., Satchwell, J. B., Vivian, J. P., So, K., Dubois, P. C., Andrews, J. M., Annese, V., Bampton, P., Barnardo, M., Bell, S., Cole, A., Connor, S. J., Creed, T., Cummings, F. R., D'Amato, M., Daneshmend, T. K. & 38 others, Fedorak, R. N., Florin, T. H., Gaya, D. R., Greig, E., Halfvarson, J., Hart, A., Irving, P., Jones, G., Karban, A., Lawrance, I., Lee, J. C., Lees, C., Lev-Tzion, R., Lindsay, J. O., Mansfield, J., Mawdsley, J., Mazhar, Z., Parkes, M., Parnell, K., Orchard, T. R., Radford-Smith, G., Russell, R. K., Reffitt, D., Satsangi, J., Silverberg, M. S., Sturniolo, G. C., Tremelling, M., Tsianos, V., Van Heel, D. A., Walsh, A., Watermeyer, G., Weersma, R. K., Zeissig, S., Rossjohn, J., Holden, A. L., International Serious Adverse Events Consortium, I. S. A. E. C., Ibd Pharmacogenetics Study Group, IBD. P. S. G. & Ahmad, T., 2014, In : Nature Genetics. 46, 10, p. 1131-1136

  Research output: Contribution to journal › Article
  106 Citations (Scopus)

• Mechanisms of initiation and progression of intestinal fibrosis in IBD

  Latella, G., Di Gregorio, J., Flati, V., Rieder, F. & Lawrance, I., 2014, In : Scandinavian Journal of Gastroenterology. 50, p. 53-65

  Research output: Contribution to journal › Review article
  78 Citations (Scopus)

• PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease

  Roberts, R. L., Wallace, M. C., Seinen, M. L., Krishnaprasad, K., Chew, A., Lawrance, I., Prosser, R., Bampton, P., Grafton, R., Simms, L., Radford-Smith, G., Andrews, J. M. & Barclay, M. L., 2014, In : American Journal of Gastroenterology. 109, p. 925-927

  Research output: Contribution to journal › Letter
  7 Citations (Scopus)

• Preventing infective complications in inflammatory bowel disease

  Mill, J. & Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 29, p. 9691-9698

  Research output: Contribution to journal › Review article

  Open Access

  • Inflammatory Bowel Diseases
  • Opportunistic Infections
  • Physicians
  • Biological Factors
  • Patient Education
  9 Citations (Scopus)

• Prostaglandin E2 and polyenylphosphatidylcholine protect against intestinal fibrosis and regulate myofibroblast function

  Baird, A., Lloyd, F. & Lawrance, I., 2014, In : Digestive Diseases & Sciences. 60, p. 1603–1616

  Research output: Contribution to journal › Article
  5 Citations (Scopus)

• Relationship between disease severity and quality of life and assessment of health care utilization and cost for ulcerative colitis in Australia: A cross-sectional, observational study

  Gibson, P. R., Vaizey, C. J., Black, C. M., Nicholls, R., Weston, A. R., Bampton, P. A., Sparrow, M. P., Lawrance, I., Selby, W. S., Andrews, J. M., Walsh, A. J., Hetzel, D. J., Macrae, F. A., Moore, G. T. C., Weltman, M., Leong, R. & Fan, T., 2014, In : Journal of Crohn's and Colitis. 8, 7, p. 598-606

  Research output: Contribution to journal › Article

  • Patient Acceptance of Health Care
  • Ulcerative Colitis
  • Health Care Costs
  • Observational Studies
  • Cross-Sectional Studies
  64 Citations (Scopus)

• Results of the 4th scientific workshop of the ECCO (I): Pathophysiology of intestinal fibrosis in IBD

  Latella, G., Rogler, G., Bamias, G., Breynaert, C., Florholmen, J. R., Pellino, G., Reif, S. S., Speca, S. & Lawrance, I., 2014, In : Journal of Crohn's and Colitis. 8, 10, p. 1147-1165

  Research output: Contribution to journal › Review article

  • Colitis
  • Inflammatory Bowel Diseases
  • Fibrosis
  • Education
  • Tissue Inhibitor of Metalloproteinases
  96 Citations (Scopus)

• The importance of validating proposed genetic profiles in IBD

  Lawrance, I., May 2014, In : Journal of Internal Medicine.

  Research output: Contribution to journal › Review article

• The role of vitamin D in gastrointestinal inflammation

  Ghaly, S. & Lawrance, I., 2014, In : Expert Review of Gastroenterology and Hepatology. 8, 8, p. 909-923

  Research output: Contribution to journal › Review article

  • Vitamin D
  • Inflammation
  • Crohn Disease
  • Inflammatory Bowel Diseases
  • Adaptive Immunity
  26 Citations (Scopus)

• What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

  Lawrance, I., 2014, In : World Journal of Gastroenterology. 20, 5, p. 1248-1258

  Research output: Contribution to journal › Article

  Open Access

  • Inflammatory Bowel Diseases
  • Tumor Necrosis Factor-alpha
  • Mercaptopurine
  • Physicians
  • Mycophenolic Acid
  9 Citations (Scopus)
• 2016

  Acute severe ulcerative colitis: Changing treatment paradigms

  Lawrance, I., 2016, In : Journal of Gastroenterology and Hepatology (Australia). 31, p. 16

  Research output: Contribution to journal › Article

• Acute Severe Ulcerative Colitis: Evidence Based Consensus Statements

  Lawrance, I., Jul 2016, In : Alimentary Pharmacology and Therapeutics.

  Research output: Contribution to journal › Editorial

  Open Access
  33 Citations (Scopus)

• A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

  Bodea, C. A., Neale, B. M., Ripke, S., International Inflammatory Bowel Disease Genetics Consortium, Lawrance, I., Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In : American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

  Research output: Contribution to journal › Article

  Open Access
  6 Citations (Scopus)

• Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

  International Inflammatory Bowel Disease Genetics Consortium, International Genetics of Ankylosing Spondylitis Consortium, International PSC Study Group, Genetic Analysis of Psoriasis Consortium & Psoriasis Association Genetics Extension, 1 May 2016, In : Nature Genetics. 48, 5, p. 510-518 9 p.

  Research output: Contribution to journal › Article

  • Sclerosing Cholangitis
  • Comorbidity
  • Chronic Disease
  • Inflammatory Bowel Diseases
  • Molecular Pathology
  260 Citations (Scopus)

• Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease

  Heap, G. A., So, K., Weedon, M., Edney, N., Bewshea, C., Singh, A., Annese, V., Beckly, J., Buurman, D., Chaudhary, R., Cole, A. T., Cooper, S. C., Creed, T., Cummings, F., de Boer, N. K., D'Inca, R., Daneshmend, T. K., Delaney, M., Dhar, A., Direkze, N. & 43 others, Dunckley, P., Gaya, D. R., Gearry, R., Gore, S., Halfvarson, J., Hart, A., Hawkey, C. J., Hoentjen, F., Iqbal, T., Irving, P., Lal, S., Lawrence, I., Lees, C. W., Lewis, S., Lockett, M., Mann, S., Mansfield, J., Mowat, C., Muller, F., Murray, C., Orchard, T., Parkes, M., Phillips, R., Pollok, R., Radford-Smith, G., Sebastian, S., Sen, S., Shirazi, T., Silverberg, M., Solomon, L., Sturniolo, G. C., Thomas, M., Tremelling, M., Tsianos, E. V., Watts, D., Weaver, S., Wesley, E., Holden, A., D'Souza, R., Mulgrew, C. J., Oram, R., Weersma, R. K. & Ahmad, T., 1 Feb 2016, In : Journal of Crohn's and Colitis. 10, 2, p. 149-158 10 p.

  Research output: Contribution to journal › Article

  • Mesalamine
  • Inflammatory Bowel Diseases
  • Kidney
  • Genome-Wide Association Study
  • Pharmaceutical Preparations
  40 Citations (Scopus)

• Concentrations of Adalimumab and Infliximab in Mothers and Newborns, and Effects on Infection

  Julsgaard, M., Christensen, L. A., Gibson, P. R., Gearry, R. B., Fallingborg, J., Hvas, C. L., Bibby, B. M., Uldbjerg, N., Connell, W. R., Rosella, O., Grosen, A., Brown, S. J., Kjeldsen, J., Wildt, S., Svenningsen, L., Sparrow, M. P., Walsh, A., Connor, S. J., Radford-Smith, G., Lawrance, I. & 3 others, Andrews, J. M., Ellard, K. & Bell, S. J., 2016, In : Gastroenterology. 151, 1, p. 110-119

  Research output: Contribution to journal › Article

  • Adalimumab
  • Infliximab
  • Newborn Infant
  • Necrosis
  • Umbilical Cord
  136 Citations (Scopus)

• Dysregulation of innate immunity in ulcerative colitis patients who fail anti-Tumor necrosis factor therapy Basic Study

  Baird, A., Mallon, D., Radford-Smith, G., Boyer, J., Piche, T., Prescott, S., Lawrance, I. & Tulic, M. K., 2016, In : World Journal of Gastroenterology. 22, 41, p. 9104-9116 13 p.

  Research output: Contribution to journal › Article

  Open Access

  • Ulcerative Colitis
  • Innate Immunity
  • Tumor Necrosis Factor-alpha
  • Toll-Like Receptors
  • Cytokines
  10 Citations (Scopus)

• High Vitamin D-Binding Protein Concentration, Low Albumin, and Mode of Remission Predict Relapse in Crohn's Disease

  Ghaly, S., Murray, K., Baird, A., Martin, K., Prosser, R., Mill, J., Simms, L. A., Hart, P. H., Radford-Smith, G., Bampton, P. A. & Lawrance, I. C., Oct 2016, In : Inflammatory Bowel Diseases. 22, 10, p. 2456-2464 9 p.

  Research output: Contribution to journal › Article

  • Vitamin D-Binding Protein
  • Crohn Disease
  • Albumins
  • Sunlight
  • Recurrence
  12 Citations (Scopus)

• Infliximab Reduces Endoscopic, but Not Clinical, Recurrence of Crohn's Disease after Ileocolonic Resection

  Regueiro, M., Feagan, B. G., Zou, B., Johanns, J., Blank, M. A., Chevrier, M., Plevy, S., Popp, J., Cornillie, F. J., Lukas, M., Danese, S., Gionchetti, P., Hanauer, S. B., Reinisch, W., Sandborn, W. J., Sorrentino, D., Rutgeerts, P., Debinski, H., Florin, T., Hetzel, D. & 136 others, Lawrance, I., Radford-Smith, G., Sloss, A., Sorrentino, D., Gassner, S., Haas, T., Reicht, G., Reinisch, W., Strasser, M., Vogelsang, H., Bossuyt, P., Dewit, O., D'Haens, G., Franchimont, D., Louis, E., Vermeire, S., Bernstein, C. N., Bourdages, R., Chiba, N., Dhalla, S. S., Feagan, B. G., Fedorak, R. N., Lachance, J. R., Panaccione, R., Ropeleski, M., Singh Salh, B., Lukas, M., Colombel, J. F., Allez, M., Desreumaux, P., Dupas, J. L., Grimaud, J. C., Hebuterne, X., Laharie, D., Lerebours, E., Peyrin-Biroulet, L., Reimund, J. M., Viennot, S., Zerbib, F., Antoni, C., Atreya, R., Baumgart, D. C., Berg, C., Boecker, U., Bramkamp, G., Bünning, C., Ehehalt, R., Howaldt, S., Kucharzik, T., Lamprecht, H. G., Mudter, J., Preiss, J. C., Schreiber, S., Seidler, U., Altorjay, I., Banai, J., Lakatos, P. L., Varga, M., Vincze, A., Avni-Biron, I., Fishman, S., Fraser, G. M., Goldin, E., Rachmilewitz, D., Annese, V., Ardizzone, S., Biancone, L., Bossa, F., Danese, S., Fries, W., Gionchetti, P., Maconi, G., Terrosu, G., Usai, P., D'Haens, G. R., Gearry, R. B., Hill, J., Rowbotham, D. S., Schultz, M., Stubbs, R. S., Wallace, D., Walmsley, R. S., Wyeth, J., Malecka-Panas, E., Paradowski, L., Regula, J., Beales, I. P., Campbell, S., Hawthorne, A. B., Parkes, M., Travis, S. P., Achkar, J. P., Behm, B. W., Bickston, S. J., Brown, K. J., Chiorean, M. V., Devilliers, W. J. S., Elliott, D. E., Grunkmeier, D., Hamilton, J. W., Hanauer, S. B., Hanson, J. S., Hardi, R., Helper, D. J., Herfarth, H., Higgins, P. D. R., Holderman, W. H., Kottoor, R., Kreines, M. D., Leman, B. I., Li, X., Loftus, E. V., Noar, M., Oikonomou, I., Onken, J., Peterson, K. A., Phillips, R. P., Randall, C. W., Ricci, M., Ritter, T., Rubin, D. T., Safdi, M., Sandborn, W. J., Sauberman, L., Scherl, E., Schwarz, R. P., Sedghi, S., Shafran, I., Sninsky, C. A., Stein, I., Swoger, J., Vecchio, J., Weinberg, D. I., Wruble, L. D., Yajnik, V. & Younes, Z., 1 Jun 2016, In : Gastroenterology. 150, 7, p. 1568-1578 11 p.

  Research output: Contribution to journal › Article

  Open Access

  • Infliximab
  • Crohn Disease
  • Recurrence
  • Placebos
  • Numbers Needed To Treat
  115 Citations (Scopus)