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  • Markus Schlaich
2014

Response to letter regarding article, "ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension"

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 20 May 2014, In : Circulation. 129, 20

Research output: Contribution to journalLetter

Open Access

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access

Substantial blood pressure reduction with renal denervation in a drug-naïve patient intolerant to antihypertensive pharmacotherapy: A case report

Xu, J., Walton, A., Hering, D., Sata, Y. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 8, p. 517-518 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Krum, H., Narkiewicz, K., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 2014, In : Hypertension. 64, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

The role of renal denervation for the treatment of resistant hypertension

McLellan, A. J. A., Kistler, P. M., Walton, A. S. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 4, p. 218-223 6 p.

Research output: Contribution to journalReview article

2013

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 9 Jul 2013, In : Circulation. 128, 2, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
217 Citations (Scopus)

Blood pressure and sympathetic nervous system response to renal denervation

Schlaich, M., Hering, D., Lambert, G., Lambert, E. & Esler, M., Feb 2013, In : Hypertension. 61, 2

Research output: Contribution to journalLetter

Open Access
8 Citations (Scopus)

Chronic kidney disease: Role of sympathetic nervous system activation and potential benefits of renal denervation

Hering, D., Esler, M. D. & Schlaich, M. P., 2013, In : EuroIntervention. 9, p. R127-R135

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cognitive performance in patients with resistant hypertension following renal sympathetic denervation

Lambert, G. W., Dhar, A. K. & Schlaich, M. P., 1 Oct 2013, In : EuroIntervention. 9, 6, p. 665-667 3 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Dabigatran elimination: Is haemodialysis effective?

McLellan, A. J. A. & Schlaich, M. P., 7 Feb 2013, In : Thrombosis and Haemostasis. 109, 4, p. 580-581 2 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Reimann, M., Steyn, H. S., Schutte, R., Smith, W., Van Rooyen, J. M., Fourie, C. M. T. & Malan, N. T., 30 Sep 2013, In : International Journal of Cardiology. 168, 2, p. 999-1005 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Defensive coping facilitates higher blood pressure and early sub-clinical structural vascular disease via alterations in heart rate variability: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G., Ziemssen, T., Reimann, M., Frasure-Smith, N., Amirkhan, J. H., Schutte, R., van Rooyen, J. M., Mels, C. M., Fourie, C. M. T., Uys, A. S. & Malan, N. T., 1 Apr 2013, In : Atherosclerosis. 227, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Devices for Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2013, Hypertension: A Companion to Braunwald's Heart Disease: Second Edition. Elsevier, p. 230-235 6 p.

Research output: Chapter in Book/Conference paperChapter

Dyslipidemia is associated with sympathetic nervous activation and impaired endothelial function in young females

Lambert, E., Straznicky, N., Sari, C. I., Eikelis, N., Hering, D., Head, G., Dixon, J., Esler, M., Schlaich, M. & Lambert, G., 1 Feb 2013, In : American Journal of Hypertension. 26, 2, p. 250-256 7 p.

Research output: Contribution to journalArticle

Open Access
40 Citations (Scopus)

Effects of acute and chronic stress on the L-arginine nitric oxide pathway in black and white South Africans: The sympathetic activity and ambulatory blood pressure in Africans study

Reimann, M., Hamer, M., Malan, N. T., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Boeger, R. H. & Malan, L., 2013, In : Psychosomatic Medicine. 75, 8, p. 751-758 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Feasibility of catheter-based renal nerve ablation and effects on sympathetic nerve activity and blood pressure in patients with end-stage renal disease

Schlaich, M. P., Bart, B., Hering, D., Walton, A., Marusic, P., Mahfoud, F., Böhm, M., Lambert, E. A., Krum, H., Sobotka, P. A., Schmieder, R. E., Ika-Sari, C., Eikelis, N., Straznicky, N., Lambert, G. W. & Esler, M. D., 3 Oct 2013, In : International Journal of Cardiology. 168, 3, p. 2214-2220 7 p.

Research output: Contribution to journalArticle

99 Citations (Scopus)

Higher heart rate increases risk of diabetes among men: The Australian Diabetes Obesity and Lifestyle (AusDiab) study

Grantham, N. M., Magliano, D. J., Tanamas, S. K., Söderberg, S., Schlaich, M. P. & Shaw, J. E., Apr 2013, In : Diabetic Medicine. 30, 4, p. 421-427 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
Open Access
22 Citations (Scopus)

International expert consensus statement: Percutaneous transluminal renal denervation for the treatment of resistant hypertension

Schlaich, M. P., Schmieder, R. E., Bakris, G., Blankestijn, P. J., Böhm, M., Campese, V. M., Francis, D. P., Grassi, G., Hering, D., Katholi, R., Kjeldsen, S., Krum, H., Mahfoud, F., Mancia, G., Messerli, F. H., Narkiewicz, K., Parati, G., Rocha-Singh, K. J., Ruilope, L. M., Rump, L. C. & 8 others, Sica, D. A., Sobotka, P. A., Tsioufis, C., Vonend, O., Weber, M. A., Williams, B., Zeller, T. & Esler, M. D., 3 Dec 2013, In : Journal of the American College of Cardiology. 62, 22, p. 2031-2045 15 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Percutaneous transluminal renal denervation: A potential treatment option for polycystic kidney disease-related pain?

Shetty, S., Roberts, T. J. & Schlaich, M. P., 2013, In : International Journal of Cardiology. 162, 3, p. e58-e59

Research output: Contribution to journalLetter

18 Citations (Scopus)

Rationale and design of a large registry on renal denervation: The Global SYMPLICITY registry

Böhm, M., Mahfoud, F., Ukena, C., Bauer, A., Fleck, E., Hoppe, U. C., Kintscher, U., Narkiewicz, K., Negoita, M., Ruilope, L., Rump, L. C., Schlaich, M., Schmieder, R., Sievert, H., Weil, J., Williams, B., Zeymer, U. & Mancia, G., Aug 2013, In : EuroIntervention. 9, 4, p. 484-492 9 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Renal nerve ablation reduces augmentation index in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Ika-Sari, C., Walton, A. S., Krum, H., Sobotka, P. A., Mahfoud, F., Böhm, M., Lambert, G. W., Esler, M. D. & Schlaich, M. P., Sep 2013, In : Journal of Hypertension. 31, 9, p. 1893-1900 8 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)

Renal sympathetic nerve ablation for the management of resistant hypertension: An update

Thorp, A. A., Larsen, R. N. & Schlaich, M. P., Nov 2013, In : Current Opinion in Nephrology and Hypertension. 22, 6, p. 607-614 8 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)

Renal sympathetic nerve ablation for treatment-resistant hypertension

Krum, H., Schlaich, M. & Sobotka, P., Oct 2013, In : British Journal of Clinical Pharmacology. 76, 4, p. 495-503 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Response to quality of life after renal denervation

Lambert, G. W., Hering, D., Esler, M. D., Marusic, P., Lambert, E. A., Tanamas, S. K., Shaw, J., Krum, H., Dixon, J. B., Barton, D. A. & Schlaich, M. P., Apr 2013, In : Hypertension. 61, 4

Research output: Contribution to journalLetter

Open Access
2 Citations (Scopus)
2 Citations (Scopus)

Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension

Hering, D., Lambert, E. A., Marusic, P., Walton, A. S., Krum, H., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 1 Feb 2013, In : Hypertension. 61, 2, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
251 Citations (Scopus)

Sympathetic and vascular dysfunction in adult patients with Fontan circulation

Lambert, E., D'Udekem, Y., Cheung, M., Sari, C. I., Inman, J., Ahimastos, A., Eikelis, N., Pathak, A., King, I., Grigg, L., Schlaich, M. & Lambert, G., 20 Aug 2013, In : International Journal of Cardiology. 167, 4, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

The relation of glucose metabolism to left ventricular mass and function and sympathetic nervous system activity in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Karapanagiotidis, S., Wong, C., Eikelis, N., Richards, K. L., Lee, G., Nestel, P. J., Dixon, J. B., Lambert, G. W., Schlaich, M. P. & Lambert, E. A., 1 Feb 2013, In : Journal of Clinical Endocrinology and Metabolism. 98, 2

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)

Treating resistant hypertension now and in the future

Sata, Y., Xu, J., Hering, D. & Schlaich, M., 2013, In : Medicine Today. 14, 1, p. 20-27 8 p.

Research output: Contribution to journalShort survey

2010

Association between the sympathetic firing pattern and anxiety level in patients with the metabolic syndrome and elevated blood pressure

Lambert, E., Dawood, T., Straznicky, N., Sari, C., Schlaich, M., Esler, M. & Lambert, G., Mar 2010, In : Journal of Hypertension. 28, 3, p. 543-550 8 p.

Research output: Contribution to journalArticle

73 Citations (Scopus)
1 Citation (Scopus)

Controlling Blood Pressure without Drugs – Developing New Strategies

Schlaich, M. & Esler, M. D., 2010, In : European Cardiology. 6, 2, p. 18-21

Research output: Contribution to journalReview article

European Society of Hypertension Working Group on Obesity Antihypertensive effects of weight loss: Myth or reality?

Straznicky, N., Grassi, G., Esler, M., Lambert, G., Dixona, J., Lambert, E., Jordanc, J. & Schlaicha, M., 1 Apr 2010, In : Journal of Hypertension. 28, 4, p. 637-643 7 p.

Research output: Contribution to journalReview article

33 Citations (Scopus)

Interventionelle renale sympathektomie zur behandlung der therapieresistenten hypertonie

Translated title of the contribution: Interventional renal denervation for resistant hypertensionMahfoud, F., Kindermann, M., Ukena, C., Sobotka, P. A., Kindermann, I., Schlaich, M. & Böhm, M., 8 Oct 2010, In : Journal fur Hypertonie. 14, 3, p. 18-20 3 p.

Research output: Contribution to journalShort survey

New therapeutic approaches to resistant hypertension

Schlaich, M. P., Krum, H. & Esler, M. D., Aug 2010, In : Current Hypertension Reports. 12, 4, p. 296-302 7 p.

Research output: Contribution to journalReview article

10 Citations (Scopus)

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

Esler, M., Lambert, E. & Schlaich, M., Dec 2010, In : Journal of Applied Physiology. 109, 6, p. 1996-1998 3 p.

Research output: Contribution to journalArticle

87 Citations (Scopus)

Rebuttal from Esler, Lambert, and Schlaich.

Esler, M., Lambert, E. & Schlaich, M., 2010, In : Journal of applied physiology (Bethesda, Md. : 1985). 109, 6, p. 2000-2001 2 p.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Renal artery radiofrequency ablation for refractory hypertension

Schlaich, M., 2010, In : Cardiology in General Practice. 113, p. 16-18

Research output: Contribution to journalReview article

Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves

Hennebry, S. C., Eikelis, N., Socratous, F., Desir, G., Lambert, G. & Schlaich, M., Mar 2010, In : Molecular Psychiatry. 15, 3, p. 234-236 3 p.

Research output: Contribution to journalLetter

Open Access
63 Citations (Scopus)

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): A randomised controlled trial

Esler, M. D., Krum, H., Sobotka, P. A., Schlaich, M. P., Schmieder, R. E., Böhm, M., Mahfoud, F., Sievert, H., Wunderlich, N., Rump, L. C., Vonend, O., Uder, M., Lobo, M., Caulfield, M., Erglis, A., Azizi, M., Sapoval, M., Thambar, S., Persu, A., Renkin, J. & 24 others, Schunkert, H., Weil, J., Hoppe, U. C., Walton, T., Scheinert, D., Binder, T., Januszewicz, A., Witkowski, A., Ruilope, L. M., Whitbourn, R., Bruck, H., Downes, M., Lüscher, T. F., Jardine, A. G., Webster, M. W., Zeller, T., Sadowski, J., Bartus, K., Straley, C. A., Barman, N. C., Lee, D. P., Witteles, R. M., Bhalla, V. & Massaro, J. M., 4 Dec 2010, In : The Lancet. 376, 9756, p. 1903-1909 7 p.

Research output: Contribution to journalArticle

1691 Citations (Scopus)

Renal sympathetic nerve ablation: The new frontier in the treatment of hypertension

Schlaich, M. P., Krum, H. & Sobotka, P. A., 1 Feb 2010, In : Current Hypertension Reports. 12, 1, p. 39-46 8 p.

Research output: Contribution to journalReview article

35 Citations (Scopus)

Stress reactivity and its association with increased cardiovascular risk: A role for the sympathetic nervous system?

Lambert, G., Schlaich, M., Lambert, E., Dawood, T. & Esler, M., Jun 2010, In : Hypertension. 55, 6

Research output: Contribution to journalLetter

Open Access
10 Citations (Scopus)

Sympathetic nervous activation in obesity and the metabolic syndrome-Causes, consequences and therapeutic implications

Lambert, G. W., Straznicky, N. E., Lambert, E. A., Dixon, J. B. & Schlaich, M. P., 1 May 2010, In : Pharmacology and Therapeutics. 126, 2, p. 159-172 14 p.

Research output: Contribution to journalReview article

219 Citations (Scopus)

Sympathetic nervous and adrenal medullary systems as targets for treatment in metabolic syndrome-associated disorders

Lambert, G. W., Straznicky, N. E., Lambert, E. A., Dixon, J. & Schlaich, M., 2010, In : Pharmacology & Therapeutics. 216, 2, p. 159-172

Research output: Contribution to journalReview article

Sympathetic nervous system activity is associated with obesity-induced subclinical organ damage in young adults

Lambert, E., Sari, C. I., Dawood, T., Nguyen, J., McGrane, M., Eikelis, N., Chopra, R., Wong, C., Chatzivlastou, K., Head, G., Straznicky, N., Esler, M., Schlaich, M. & Lambert, G., 1 Sep 2010, In : Hypertension. 56, 3, p. 351-358 8 p.

Research output: Contribution to journalArticle

Open Access
140 Citations (Scopus)

Sympathetic neural adaptation to hypocaloric diet with or without exercise training in obese metabolic syndrome subjects

Straznicky, N. E., Lambert, E. A., Nestel, P. J., McGrane, M. T., Dawood, T., Schlaich, M. P., Masuo, K., Eikelis, N., De Courten, B., Mariani, J. A., Esler, M. D., Socratous, F., Chopra, R., Sari, C. I., Paul, E. & Lambert, G. W., 2010, In : Diabetes. 59, 1, p. 71-79 9 p.

Research output: Contribution to journalArticle

Open Access
70 Citations (Scopus)

Sympathoexcitation in calcineurin inhibitor-induced hypertension: Villain or innocent bystander?

Schlaich, M. P. & Grassi, G., Sep 2010, In : Journal of Hypertension. 28, 9, p. 1809-1810 2 p.

Research output: Contribution to journalComment/debate

3 Citations (Scopus)