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Author

  • Markus Schlaich
2016

Overexpression and knock-down studies highlight that a disintegrin and metalloproteinase 28 controls proliferation and migration in human prostate cancer

Rudnicka, C., Mochizuki, S., Okada, Y., McLaughlin, C., Leedman, P. J., Stuart, L., Epis, M., Hoyne, G., Boulos, S., Johnson, L., Schlaich, M. & Matthews, V., 2016, In : Medicine (United States). 95, 40, p. 1-8 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Renal artery anatomy affects the blood pressure response to renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Duval, J., Lee, R., Sata, Y., Krum, H., Lambert, E., Peter, K., Head, G., Lambert, G., Esler, M. D. & Schlaich, M., 1 Jan 2016, In : International Journal of Cardiology. 202, p. 388-393 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Renal denervation for resistant hypertension: Closing in on potential confounders

Schlaich, M. P., Schultz, C. & Shetty, S., 2016, In : Journal of Hypertension. 34, 8, p. 1505-1506 2 p.

Research output: Contribution to journalLetter

Renal denervation in hypertensive patients not on blood pressure lowering drugs

De Jager, R. L., Sanders, M. F., Bots, M. L., Lobo, M. D., Ewen, S., Beeftink, M. M. A., Böhm, M., Daemen, J., Dörr, O., Hering, D., Mahfoud, F., Nef, H., Ott, C., Saxena, M., Schmieder, R. E., Schlaich, M., Spiering, W., Tonino, P. A. L., Verloop, W. L., Vink, E. E. & 4 others, Vonken, E. J., Voskuil, M., Worthley, S. G. & Blankestijn, P. J., 2016, In : Clinical Research in Cardiology. 105, 9, p. 755-762

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes fromthe global SYMPLICITY registry

Böhm, M., Ukena, C., Ewen, S., Linz, D., Zivanovic, I., Hoppe, U., Narkiewicz, K., Ruilope, L., Schlaich, M., Negoita, M., Schmieder, R., Williams, B., Zeymer, U., Zirlik, A., Mancia, G. & Mahfoud, F., 2016, In : Journal of Hypertension. 34, 12, p. 2480-2486 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Renal Nitric Oxide Deficiency and Chronic Kidney Disease in Young Sheep Born with a Solitary Functioning Kidney

Singh, R. R., Easton, L. K., Booth, L. C., Schlaich, M. P., Head, G. A., Moritz, K. M. & Denton, K. M., 26 May 2016, In : Scientific Reports. 6, 26777.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)

Residual sympathetic responsiveness after catheter-based renal denervation: Lessons from renal nerve stimulation

Schlaich, M. P., Sata, Y. & Hering, D., 2016, In : Hypertension. 67, 6, p. 1117-1118 2 p.

Research output: Contribution to journalLetter

2 Citations (Scopus)

Sympathetic nervous response to ischemia-reperfusion injury in humans is altered with remote ischemic preconditioning

Lambert, E. A., Thomas, C. J., Hemmes, R., Eikelis, N., Pathak, A., Schlaich, M. & Lambert, G. W., 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 311, 2, p. H364-H370

Research output: Contribution to journalArticle

27 Citations (Scopus)
8 Citations (Scopus)

Three-year changes of prothrombotic factors in a cohort of South Africans with a high clinical suspicion of obstructive sleep apnea

Von Känel, R., Malan, N. T., Hamer, M., Lambert, G. W., Schlaich, M., Reimann, M. & Malan, L., 2016, In : Thrombosis and Haemostasis. 115, 1, p. 63-72

Research output: Contribution to journalArticle

5 Citations (Scopus)
Open Access
File
5 Citations (Scopus)
238 Downloads (Pure)
2014

Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects

Forbes, J. M., Sourris, K. C., De Courten, M. P. J., Dougherty, S. L., Chand, V., Lyons, J. G., Bertovic, D., Coughlan, M. T., Schlaich, M. P., Soldatos, G., Cooper, M. E., Straznicky, N. E., Kingwell, B. A. & De Courten, B., 1 Feb 2014, In : Amino Acids. 46, 2, p. 321-326 6 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

A randomized controlled trial of the effects of pioglitazone treatment on sympathetic nervous system activity and cardiovascular function in obese subjects with metabolic syndrome

Straznicky, N. E., Grima, M. T., Sari, C. I., Eikelis, N., Lambert, G. W., Nestel, P. J., Karapanagiotidis, S., Wong, C., Richards, K., Marusic, P., Dixon, J. B., Schlaich, M. P. & Lambert, E. A., 1 Sep 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 9, p. E1701-E1707

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)

Association of vitamin D status and blood pressure response after renal denervation

Pöss, J., Mahfoud, F., Ukena, C., Esler, M. D., Schlaich, M., Hering, D., Cremers, B., Laufs, U. & Böhm, M., 2014, In : Clinical Research in Cardiology. 103, 1, p. 41-47 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 2014, In : The Lancet. 383, 9932, p. 1885-1886 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Baroreflex sensitivity: A reliable predictor of response to renal denervation?

Hering, D., Esler, M. D. & Schlaich, M. P., 15 Jul 2014, In : Journal of the American College of Cardiology. 64, 2, p. 232-233 2 p.

Research output: Contribution to journalLetter

Open Access

Biomarkers for the prediction of blood pressure response to renal denervation: A long way to go

Schlaich, M., 2014, In : Hypertension. 63, 5, p. 907-908 2 p.

Research output: Contribution to journalComment/debate

Open Access
4 Citations (Scopus)

Catheter-based renal denervation for treatment of patients with treatment-resistant hypertension: 36 month results from the SYMPLICITY HTN-2 randomized clinical trial

Esler, M. D., Böhm, M., Sievert, H., Rump, C. L., Schmieder, R. E., Krum, H., Mahfoud, F. & Schlaich, M. P., 7 Jul 2014, In : European Heart Journal. 35, 26, p. 1752-1759 8 p.

Research output: Contribution to journalArticle

Open Access
167 Citations (Scopus)

Chronic distress and acute vascular stress responses associated with ambulatory blood pressure in low-testosterone African men: The SABPA Study

Malan, N. T., Stalder, T., Schlaich, M. P., Lambert, G. W., Hamer, M., Schutte, A. E., Huisman, H. W., Schutte, R., Smith, W., Mels, C. M. C., Van Rooyen, J. M. & Malan, L., Jun 2014, In : Journal of Human Hypertension. 28, 6, p. 393-398 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Critical issues in patient selection, efficacy, and safety of renal denervation

Schlaich, M. P., Esler, M. D., Fink, G. D., Osborn, J. W. & Euler, D. E., Mar 2014, In : Hypertension. 63, 3, p. 426-432 7 p.

Research output: Contribution to journalReview article

Open Access
26 Citations (Scopus)

CrossTalk opposing view: Which technique for controlling resistant hypertension? Renal nerve ablation

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, p. 3937-3940 4 p.

Research output: Contribution to journalComment/debate

Open Access
5 Citations (Scopus)

Effect of renal denervation on left ventricular mass and function in patients with resistant hypertension: Data from a multi-centre cardiovascular magnetic resonance imaging trial

Mahfoud, F., Urban, D., Teller, D., Linz, D., Stawowy, P., Hassel, J. H., Fries, P., Dreysse, S., Wellnhofer, E., Schneider, G., Buecker, A., Schneeweis, C., Doltra, A., Schlaich, M. P., Esler, M. D., Fleck, E., Böhm, M. & Kelle, S., 1 Sep 2014, In : European Heart Journal. 35, 33, p. 2224-2231 8 p.

Research output: Contribution to journalArticle

Open Access
96 Citations (Scopus)

From symplicity htn-3 to the renal denervation global registry: Where do we stand and where should we go

Pathak, A., Ewen, S., Fajadet, J., Honton, B., Mahfoud, F., Marco, J., Schlaich, M., Schmieder, R., Tsioufis, K., Ukena, C. & Zeller, T., 2014, In : EuroIntervention. 10, p. 21

Research output: Contribution to journalReview article

31 Citations (Scopus)

Hypertension: Treatment-resistant hypertension-A risk factor for ESRD

Schlaich, M. P., 2014, In : Nature Reviews Nephrology. 10, 4, p. 189-190 2 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Interventional Treatments for Resistant Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2014, Comprehensive Clinical Nephrology . Johnson, R., Feehally, J. & Floege, J. (eds.). 5 ed. Philadelphia: Elsevier, p. 447-452

Research output: Chapter in Book/Conference paperChapter

Morning surge in blood pressure is associated with reactivity of the sympathetic nervous system

Lambert, E. A., Chatzivlastou, K., Schlaich, M., Lambert, G. & Head, G. A., Jun 2014, In : American Journal of Hypertension. 27, 6, p. 783-792 10 p.

Research output: Contribution to journalArticle

Open Access
33 Citations (Scopus)

Percutaneous renal denervation in patients with treatment-resistant hypertension: Final 3-year report of the Symplicity HTN-1 study

Krum, H., Schlaich, M. P., Sobotka, P. A., Böhm, M., Mahfoud, F., Rocha-Singh, K., Katholi, R. & Esler, M. D., 2014, In : The Lancet. 383, 9917, p. 622-629 8 p.

Research output: Contribution to journalArticle

429 Citations (Scopus)

Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure

Sourris, K. C., Lyons, J. G., Dougherty, S. L., Chand, V., Straznicky, N. E., Schlaich, M. P., Grima, M. T., Cooper, M. E., Kingwell, B. A., De Courten, M. P. J., Forbes, J. M. & De Courten, B., 2014, In : Clinical Chemistry and Laboratory Medicine. 52, 1, p. 129-138 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Potential future denervation targets

Gerard Leong, K. T., Walton, A., Krum, H. & Schlaich, M. P., 1 Dec 2014, In : Interventional Cardiology. 6, 6, p. 569-579 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Rebuttal from Markus P. Schlaich, Yusuke Sata and Murray D. Esler

Schlaich, M. P., Sata, Y. & Esler, M. D., 2014, In : Journal of Physiology. 592, 18, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Regulation of the sympathetic nervous system by the kidney

Larsen, R., Thorp, A. & Schlaich, M., 2014, In : Current Opinion in Nephrology and Hypertension. 23, 1, p. 61-68 8 p.

Research output: Contribution to journalReview article

11 Citations (Scopus)

Renal denervation: Current implications and future perspectives

Xu, J., Hering, D., Sata, Y., Walton, A., Krum, H., Esler, M. D. & Schlaich, M. P., 2014, In : Clinical Science. 126, 1, p. 41-53 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Renal denervation and pulmonary vein isolation in patients with drug resistant hypertension and symptomatic atrial fibrillation

Wilson, S., Kistler, P. M., Mclellan, A. J. A., Hering, D. & Schlaich, M., 2014, In : JOURNAL OF ATRIAL FIBRILLATION. 7, 4, p. 69-74

Research output: Contribution to journalReview article

1 Citation (Scopus)

Renal denervation for resistant hypertension—the Symplicity HTN-1 study – Authors' reply

Krum, H., Sobotka, P., Schlaich, M., Bohm, M. & Esler, M., 1 May 2014, In : The Lancet. 383, 9932, p. 1885-1886

Research output: Contribution to journalLetter

Renal oxygenation in acute renal ischemia-reperfusion injury

Abdelkader, A., Ho, J., Ow, C. P. C., Eppel, G. A., Rajapakse, N. W., Schlaich, M. P. & Evans, R. G., 1 May 2014, In : American Journal of Physiology - Renal Physiology. 306, 9

Research output: Contribution to journalArticle

47 Citations (Scopus)

Response to letter regarding article, "ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension"

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 20 May 2014, In : Circulation. 129, 20

Research output: Contribution to journalLetter

Open Access

Response to more research is needed to investigate the effect of denervation on blood pressure

Schlaich, M., Esler, M., Fink, G., Osborn, J. & Euler, D., Apr 2014, In : Hypertension. 63, 4

Research output: Contribution to journalLetter

Open Access

Substantial blood pressure reduction with renal denervation in a drug-naïve patient intolerant to antihypertensive pharmacotherapy: A case report

Xu, J., Walton, A., Hering, D., Sata, Y. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 8, p. 517-518 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension

Hering, D., Marusic, P., Walton, A. S., Lambert, E. A., Krum, H., Narkiewicz, K., Lambert, G. W., Esler, M. D. & Schlaich, M. P., 2014, In : Hypertension. 64, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Open Access
99 Citations (Scopus)

Sympathetic activity and markers of cardiovascular risk in nondiabetic severely obese patients: The effect of the initial 10% weight loss

Lambert, E. A., Rice, T., Eikelis, N., Straznicky, N. E., Lambert, G. W., Head, G. A., Hensman, C., Schlaich, M. P. & Dixon, J. B., 2014, In : American Journal of Hypertension. 27, 10, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

Open Access
23 Citations (Scopus)

The effects of dietary weight loss on indices of norepinephrine turnover: Modulatory influence of hyperinsulinemia

Straznicky, N. E., Lambert, E. A., Grima, M. T., Eikelis, N., Richards, K., Nestel, P. J., Dawood, T., Masuo, K., Sari, C. I., Dixon, J. B., Esler, M. D., Paul, E., Schlaich, M. P. & Lambert, G. W., 2014, In : Obesity. 22, 3, p. 652-662 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

The role of renal denervation for the treatment of resistant hypertension

McLellan, A. J. A., Kistler, P. M., Walton, A. S. & Schlaich, M. P., 2014, In : Journal of Human Hypertension. 28, 4, p. 218-223 6 p.

Research output: Contribution to journalReview article

2013

Ambulatory blood pressure changes after renal sympathetic denervation in patients with resistant hypertension

Mahfoud, F., Ukena, C., Schmieder, R. E., Cremers, B., Rump, L. C., Vonend, O., Weil, J., Schmidt, M., Hoppe, U. C., Zeller, T., Bauer, A., Ott, C., Blessing, E., Sobotka, P. A., Krum, H., Schlaich, M., Esler, M. & Böhm, M., 9 Jul 2013, In : Circulation. 128, 2, p. 132-140 9 p.

Research output: Contribution to journalArticle

Open Access
217 Citations (Scopus)

Blood pressure and sympathetic nervous system response to renal denervation

Schlaich, M., Hering, D., Lambert, G., Lambert, E. & Esler, M., Feb 2013, In : Hypertension. 61, 2

Research output: Contribution to journalLetter

Open Access
8 Citations (Scopus)

Chronic kidney disease: Role of sympathetic nervous system activation and potential benefits of renal denervation

Hering, D., Esler, M. D. & Schlaich, M. P., 2013, In : EuroIntervention. 9, p. R127-R135

Research output: Contribution to journalArticle

26 Citations (Scopus)

Cognitive performance in patients with resistant hypertension following renal sympathetic denervation

Lambert, G. W., Dhar, A. K. & Schlaich, M. P., 1 Oct 2013, In : EuroIntervention. 9, 6, p. 665-667 3 p.

Research output: Contribution to journalEditorial

1 Citation (Scopus)

Dabigatran elimination: Is haemodialysis effective?

McLellan, A. J. A. & Schlaich, M. P., 7 Feb 2013, In : Thrombosis and Haemostasis. 109, 4, p. 580-581 2 p.

Research output: Contribution to journalEditorial

3 Citations (Scopus)

Defensive active coping facilitates chronic hyperglycaemia and endothelial dysfunction in African men: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G. W., Ziemssen, T., Reimann, M., Steyn, H. S., Schutte, R., Smith, W., Van Rooyen, J. M., Fourie, C. M. T. & Malan, N. T., 30 Sep 2013, In : International Journal of Cardiology. 168, 2, p. 999-1005 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Defensive coping facilitates higher blood pressure and early sub-clinical structural vascular disease via alterations in heart rate variability: The SABPA study

Malan, L., Hamer, M., Schlaich, M. P., Lambert, G., Ziemssen, T., Reimann, M., Frasure-Smith, N., Amirkhan, J. H., Schutte, R., van Rooyen, J. M., Mels, C. M., Fourie, C. M. T., Uys, A. S. & Malan, N. T., 1 Apr 2013, In : Atherosclerosis. 227, 2, p. 391-397 7 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Devices for Hypertension

Krum, H., Schlaich, M. & Sobotka, P. A., 2013, Hypertension: A Companion to Braunwald's Heart Disease: Second Edition. Elsevier, p. 230-235 6 p.

Research output: Chapter in Book/Conference paperChapter